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The map label for this gene is tldD [H]

Identifier: 119944885

GI number: 119944885

Start: 1416461

End: 1417906

Strand: Direct

Name: tldD [H]

Synonym: Ping_1129

Alternate gene names: 119944885

Gene position: 1416461-1417906 (Clockwise)

Preceding gene: 119944884

Following gene: 119944886

Centisome position: 31.07

GC content: 44.05

Gene sequence:

>1446_bases
ATGTCCTTCGATAAAGTATGCGAACGATTTTTAGCCCCTGCACAATTACAAATTAGTGATTTAGAATCTCAGCTTGCAGC
TCTTAATAGCAATCAAATTGATTATGCCGACTTTTATTTTCAGTCAAGTCGACACGAATCGTGGTTGTTGGAAGATGGGA
TTGTCAAAGATGGCAGTTATAACATTGAGAAAGGTGTTGGCATCCGTGCGGTTTCAGGAGAAAAAACAGGTTTTGCCTAT
TCTGATCAAATTTCGTTAAAAGCAATTAAAGAGGCCGCTGATGCGGCTAAAAGTATTGTTAAAAGTGGTCAGGAAAAACA
GCTAAAACTTATTCTGCCAACCCCTTCGAAGTTAATTTATGGTGAATCCGATCCTCTGATAAGTTTATCGAGAGAGAAAA
AAATTGCGCTCTTAAAGCAGGTTGATCAGTTTACCCGCGCCTTAGAGCCTTCGGTCACCGATGTCACTGTCTCTCTAAAT
GCTGTTTATGAAGAAATTCTGGTGGCCGCGACCGACGGTACCTTAGCCACTGATATTCGCCCGTTAGTTCGTTTTGGTTG
CTCGGTGTTGATTGAAAAAAAGGGTAAACGAGAGCGTGGCAGTGCAGGTGGCGGTGGACGTTTTGATTTGGACTATTTTA
TTGATAGCAGCGAAGGAGAAGAAGTTGTGTTCGGTTATGCGCGTGCAGCCGTTCATCAAGCTTTGACTAATATTGAGGCT
ATCGACGCGCCCGCAGGCTCAATGCCTGTTATTGTTGGTGCAGGCTGGCCGGGTGTGTTATTACATGAAGCAGTAGGACA
TGGTTTAGAAGGTGACTTTAATCGTAAAGGTTCATCGGCTTACGCGGGACGCATTGGTGACAAAGTCGCGTCAGAGCAGT
GTACTATCATTGATGACGGTACCCTTGGAGATCGTCGCGGCTCTCTTAATATCGATGATGAAGGCACTAAAACTCAACGT
AATGTGTTAATCGAAAAAGGTGTTTTAAAAGGTTATATGCAGGATAAAATGAATGCTCGATTGATGGGGGTTGCACCTAC
CGGCAACGGCCGCCGAGAATCCTATGCCCATTTGCCAATGCCGCGTATGACCAACACTTTTATGCTTAATGGCACTTATG
CTCATGAAGAATTAATTGAAAGTGTTAAAAAAGGTATTTATGCACCTAACTTTGGTGGAGGTCAGGTTGACATCACCTCG
GGAAAATTTGTGTTCTCCGCTTCCGAGGCTTACCTGATTGAAAATGGTAAAATCACTACACCGATTAAAGGTGCTACCCT
GATTGGTAACGGTTTTGATACGATGCAACAAATCTCTATGGTCGCCAATAATATGGCGCTGGATTCAGGTGTCGGTGTAT
GCGGTAAAGAGGGGCAGAGTTTGCCTGTGGGCGTGGGACAACCCTCAGTGAAAGTTGATCAACTAACTGTTGGCGGGACT
AATTAA

Upstream 100 bases:

>100_bases
GAAAAATCACAGATAGAAAAAATTCGTCAAGCTATGCCGATACTTGAGCATAACCGTTTTACAACCTTAACCAGCTTTTA
AAAGTTTAAAGGAAATATTC

Downstream 100 bases:

>100_bases
ACAAATTTTCTGCAAAGTAAACTGGTCTAGTGTGAAGCGCTAGGCTTAGGCTGGTTATTTTAGGGATTTAAAATAATTAA
GTTAGGGTTAATGTTAACGC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSFDKVCERFLAPAQLQISDLESQLAALNSNQIDYADFYFQSSRHESWLLEDGIVKDGSYNIEKGVGIRAVSGEKTGFAY
SDQISLKAIKEAADAAKSIVKSGQEKQLKLILPTPSKLIYGESDPLISLSREKKIALLKQVDQFTRALEPSVTDVTVSLN
AVYEEILVAATDGTLATDIRPLVRFGCSVLIEKKGKRERGSAGGGGRFDLDYFIDSSEGEEVVFGYARAAVHQALTNIEA
IDAPAGSMPVIVGAGWPGVLLHEAVGHGLEGDFNRKGSSAYAGRIGDKVASEQCTIIDDGTLGDRRGSLNIDDEGTKTQR
NVLIEKGVLKGYMQDKMNARLMGVAPTGNGRRESYAHLPMPRMTNTFMLNGTYAHEELIESVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIENGKITTPIKGATLIGNGFDTMQQISMVANNMALDSGVGVCGKEGQSLPVGVGQPSVKVDQLTVGGT
N

Sequences:

>Translated_481_residues
MSFDKVCERFLAPAQLQISDLESQLAALNSNQIDYADFYFQSSRHESWLLEDGIVKDGSYNIEKGVGIRAVSGEKTGFAY
SDQISLKAIKEAADAAKSIVKSGQEKQLKLILPTPSKLIYGESDPLISLSREKKIALLKQVDQFTRALEPSVTDVTVSLN
AVYEEILVAATDGTLATDIRPLVRFGCSVLIEKKGKRERGSAGGGGRFDLDYFIDSSEGEEVVFGYARAAVHQALTNIEA
IDAPAGSMPVIVGAGWPGVLLHEAVGHGLEGDFNRKGSSAYAGRIGDKVASEQCTIIDDGTLGDRRGSLNIDDEGTKTQR
NVLIEKGVLKGYMQDKMNARLMGVAPTGNGRRESYAHLPMPRMTNTFMLNGTYAHEELIESVKKGIYAPNFGGGQVDITS
GKFVFSASEAYLIENGKITTPIKGATLIGNGFDTMQQISMVANNMALDSGVGVCGKEGQSLPVGVGQPSVKVDQLTVGGT
N
>Mature_480_residues
SFDKVCERFLAPAQLQISDLESQLAALNSNQIDYADFYFQSSRHESWLLEDGIVKDGSYNIEKGVGIRAVSGEKTGFAYS
DQISLKAIKEAADAAKSIVKSGQEKQLKLILPTPSKLIYGESDPLISLSREKKIALLKQVDQFTRALEPSVTDVTVSLNA
VYEEILVAATDGTLATDIRPLVRFGCSVLIEKKGKRERGSAGGGGRFDLDYFIDSSEGEEVVFGYARAAVHQALTNIEAI
DAPAGSMPVIVGAGWPGVLLHEAVGHGLEGDFNRKGSSAYAGRIGDKVASEQCTIIDDGTLGDRRGSLNIDDEGTKTQRN
VLIEKGVLKGYMQDKMNARLMGVAPTGNGRRESYAHLPMPRMTNTFMLNGTYAHEELIESVKKGIYAPNFGGGQVDITSG
KFVFSASEAYLIENGKITTPIKGATLIGNGFDTMQQISMVANNMALDSGVGVCGKEGQSLPVGVGQPSVKVDQLTVGGTN

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=480, Percent_Identity=64.375, Blast_Score=623, Evalue=1e-180,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51506; Mature: 51375

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDKVCERFLAPAQLQISDLESQLAALNSNQIDYADFYFQSSRHESWLLEDGIVKDGSY
CCHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHEEECCCCCCEEECCCEECCCCC
NIEKGVGIRAVSGEKTGFAYSDQISLKAIKEAADAAKSIVKSGQEKQLKLILPTPSKLIY
CCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
GESDPLISLSREKKIALLKQVDQFTRALEPSVTDVTVSLNAVYEEILVAATDGTLATDIR
CCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHEEEECCCCHHHHHH
PLVRFGCSVLIEKKGKRERGSAGGGGRFDLDYFIDSSEGEEVVFGYARAAVHQALTNIEA
HHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCHH
IDAPAGSMPVIVGAGWPGVLLHEAVGHGLEGDFNRKGSSAYAGRIGDKVASEQCTIIDDG
CCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
TLGDRRGSLNIDDEGTKTQRNVLIEKGVLKGYMQDKMNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTFMLNGTYAHEELIESVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITT
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PIKGATLIGNGFDTMQQISMVANNMALDSGVGVCGKEGQSLPVGVGQPSVKVDQLTVGGT
CCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
N
C
>Mature Secondary Structure 
SFDKVCERFLAPAQLQISDLESQLAALNSNQIDYADFYFQSSRHESWLLEDGIVKDGSY
CHHHHHHHHCCCCEEEHHHHHHHHHHHCCCCCCHHHHEEECCCCCCEEECCCEECCCCC
NIEKGVGIRAVSGEKTGFAYSDQISLKAIKEAADAAKSIVKSGQEKQLKLILPTPSKLIY
CCCCCCEEEEECCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEE
GESDPLISLSREKKIALLKQVDQFTRALEPSVTDVTVSLNAVYEEILVAATDGTLATDIR
CCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHEEEECCCCHHHHHH
PLVRFGCSVLIEKKGKRERGSAGGGGRFDLDYFIDSSEGEEVVFGYARAAVHQALTNIEA
HHHHHCCCEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHHHCCHH
IDAPAGSMPVIVGAGWPGVLLHEAVGHGLEGDFNRKGSSAYAGRIGDKVASEQCTIIDDG
CCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECC
TLGDRRGSLNIDDEGTKTQRNVLIEKGVLKGYMQDKMNARLMGVAPTGNGRRESYAHLPM
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEECCCC
PRMTNTFMLNGTYAHEELIESVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIENGKITT
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCEEEEECCEEEEECCCEEEEECCEEEC
PIKGATLIGNGFDTMQQISMVANNMALDSGVGVCGKEGQSLPVGVGQPSVKVDQLTVGGT
CCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
N
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]