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The map label for this gene is yafV [C]

Identifier: 119944884

GI number: 119944884

Start: 1415617

End: 1416441

Strand: Direct

Name: yafV [C]

Synonym: Ping_1128

Alternate gene names: 119944884

Gene position: 1415617-1416441 (Clockwise)

Preceding gene: 119944883

Following gene: 119944885

Centisome position: 31.05

GC content: 40.48

Gene sequence:

>825_bases
ATGAGTTTTAGTCTATCAGCAATACAAATGCACAGTTTGAGTCTTCCTAGTGAGAATTTAGCGCGTTTAAGGGTCTTGTT
AGCGGCATTGTCTCCTATTCCAGGGCAATTGGTGCTATTGCCTGAGAATGCTCTCTGTATTGCAGACAAAGACCATTATT
TAGCTTTATCCGAAAATTTGGGAAAGGGTTATTATCAGTCACTGTTGAGCGCCCTTGCAAAGCATTACCAATGTTATTTA
ATCTGTGGCAGTTTCCCGATTAAAAGTACCATAACGGATAAAATATTTACAACTTGTTTGGTGTTTTCGCCTTTGGGTGA
ACTCATCAGTCACTACCATAAAATGCATCTTTTTGACGCACAGGTTGCGGACCACAAAGGAATTTATAAAGAGTCAGATA
CCTTTGTTCCCGGGCAAGAAGTGAAGTTGTTTAACTGGGACTGTGGCGCTTATTCAGTCAAAGTTGGATTAACTATCTGT
TACGATTTACGTTTCCCGGGTTTATTTCAAACATTACGCAAACAGGGAGCGGATATTTTATTAGTGCCCGCCGCCTTTAC
ACAAACAACAGGACAGGCGCACTGGTTACCTTTATTACAAGCCAGGGCAATAGAAAATCAGTGTTATATTATTGCTGCGA
ATCAGAGCAGCCATGAAACCTATGGTCATTCCATGATTATTTCACCCTGGGGTGAAGTACTTGAACAATTAGCAGAGGGT
GAAGGCAGTATTCACCACCTCTTTGAAAAATCACAGATAGAAAAAATTCGTCAAGCTATGCCGATACTTGAGCATAACCG
TTTTACAACCTTAACCAGCTTTTAA

Upstream 100 bases:

>100_bases
GTTTATTTCTGCACCTGTTTTTACTCATTAGCCGTGCAGATGTTAACGTCTGCAGTATTATTGAGGATCATGATCTGTAT
ACTATGAAAGGAAACTGACA

Downstream 100 bases:

>100_bases
AAGTTTAAAGGAAATATTCATGTCCTTCGATAAAGTATGCGAACGATTTTTAGCCCCTGCACAATTACAAATTAGTGATT
TAGAATCTCAGCTTGCAGCT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: beta-alanine; CO2; NH3

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSFSLSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLALSENLGKGYYQSLLSALAKHYQCYL
ICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTIC
YDLRFPGLFQTLRKQGADILLVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEG
EGSIHHLFEKSQIEKIRQAMPILEHNRFTTLTSF

Sequences:

>Translated_274_residues
MSFSLSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLALSENLGKGYYQSLLSALAKHYQCYL
ICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTIC
YDLRFPGLFQTLRKQGADILLVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEG
EGSIHHLFEKSQIEKIRQAMPILEHNRFTTLTSF
>Mature_273_residues
SFSLSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLALSENLGKGYYQSLLSALAKHYQCYLI
CGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDAQVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTICY
DLRFPGLFQTLRKQGADILLVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEGE
GSIHHLFEKSQIEKIRQAMPILEHNRFTTLTSF

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=271, Percent_Identity=33.9483394833948, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI297632348, Length=240, Percent_Identity=36.25, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI5031947, Length=240, Percent_Identity=36.25, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI297632350, Length=240, Percent_Identity=36.25, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI297632346, Length=166, Percent_Identity=34.3373493975904, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17556280, Length=271, Percent_Identity=31.7343173431734, Blast_Score=124, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323383, Length=242, Percent_Identity=35.1239669421488, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6322335, Length=203, Percent_Identity=32.512315270936, Blast_Score=113, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21355835, Length=247, Percent_Identity=35.2226720647773, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI17933642, Length=273, Percent_Identity=34.4322344322344, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.1.6

Molecular weight: Translated: 30642; Mature: 30511

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50263 CN_HYDROLASE ; PS00392 DDC_GAD_HDC_YDC ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSLSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLALSENL
CCCCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEECCCC
GKGYYQSLLSALAKHYQCYLICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDA
CCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTICYDLRFPGLFQTLRKQGADIL
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHHCCCCEE
LVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEG
EEECHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHCC
EGSIHHLFEKSQIEKIRQAMPILEHNRFTTLTSF
CCHHHHHHHHHHHHHHHHHCCHHHCCCEEEECCC
>Mature Secondary Structure 
SFSLSAIQMHSLSLPSENLARLRVLLAALSPIPGQLVLLPENALCIADKDHYLALSENL
CCCCHHHEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCEEEECCCC
GKGYYQSLLSALAKHYQCYLICGSFPIKSTITDKIFTTCLVFSPLGELISHYHKMHLFDA
CCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVADHKGIYKESDTFVPGQEVKLFNWDCGAYSVKVGLTICYDLRFPGLFQTLRKQGADIL
HHHCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEEEEECCCCHHHHHHHHCCCCEE
LVPAAFTQTTGQAHWLPLLQARAIENQCYIIAANQSSHETYGHSMIISPWGEVLEQLAEG
EEECHHHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHCC
EGSIHHLFEKSQIEKIRQAMPILEHNRFTTLTSF
CCHHHHHHHHHHHHHHHHHCCHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-carbamoyl-beta-alanine; H2O

Specific reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]