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The map label for this gene is hisC1 [H]

Identifier: 119944873

GI number: 119944873

Start: 1399716

End: 1400828

Strand: Direct

Name: hisC1 [H]

Synonym: Ping_1116

Alternate gene names: 119944873

Gene position: 1399716-1400828 (Clockwise)

Preceding gene: 119944872

Following gene: 119944874

Centisome position: 30.7

GC content: 43.85

Gene sequence:

>1113_bases
ATGAGCTGTGATTTTTTAACGCTTGCTAATGCGGGGGTGCAAAAACTGCATCCCTACCAAGCCGGTAAACCAACGTCTGA
ATTAGAACGAGAACTTGGCATCAGTGATATTGTCAAACTTGCTTCCAATGAAAATCCGTTAGGTCTGAGTGAGAAAGTGA
AATCTGCACTGCAAAGTGAATTTTCTGAATTAGCCCGTTATCCAGATGCCAACGGTTTTTACCTTAAGCAGGCACTTGCC
GATAAATATAACGTCGGGTTAAATCAGGTGACCCTAGGAAACGGCTCAAATGATTTGCTTGAACTGGTTGCGCGGGCATT
TGTAAGCGCTGAAAATGAAGTGATATTTGCGCAGTTTGCTTTTGTTGTTTATCCAATAGTGACACAAGCGATTGGCGCAA
AAGCAGTGGTTGTTCCGGCAAAGCATTACGGTCATGATTTAGCGGCAATGGCCGCTGCCGTGACGGATAAAACAAAACTT
ATCTTTATTGCCAATCCGAATAACCCAACGGGCACTTTTCTAGAAGCGGCTGACATTCTAGCCTTTCTGAGTAAGGTGCC
GGCGCATGTCTTAGTCGTATTGGATGAGGCCTATTTTGAATATGCAGCGCCCGAACGACGTGGTAATGCTATCGCATGGA
TTAAAGATTTTCCCAATTTAATTGTTTCCCGAACCTTCTCAAAAGCCTATGGTCTTGCGGGCTTGCGTGTCGGTTACAGC
GTTTCAAATCCGCAAATTGCAGATATCCTTAATCGCGTACGCCAACCCTTTAACTGTAATGCTCTAGCGCTTAAAGCGGC
AGAGACCGTTTTACAAGATGATGAGTATTTACAGGCGGGGATTAAGTTAAATAATGCGGGCATGGCAGACTTAAGTGCTT
TTTTCAGTCAACATAACCTTGAATATATTCCTTCAATGGGAAACTTTATTACGGTCAATGTTGGCCAATCTGGGGACGTT
GTCTATCAGGCGTTATTACATGAAGGTGTGATTGTACGCCCGATAACGGGCTACGGCTTAAGCGACCATCTGCGTATTAG
CATCGGCCTGTTCGATGAAAACCAGCGTTTTAAACAAGCCTTAGTTAAAGTGCTTAAGTTAGATCAAAAATAG

Upstream 100 bases:

>100_bases
GCACTTAAAAAGTTCCCTAAAACCATCCAGTTTAAACACCCTCAGTAGAGGGGGTGATAATCGGTTAATACAAATTGCTA
TTAGAAACTAAGGATTAAAG

Downstream 100 bases:

>100_bases
AGGATAGGATGGAACAATTATTATTACAGCCAATTGCTAAGGTGGACGGTGAAATTAACCTACCTGGCTCTAAGAGCCTT
TCTAATCGTGCGCTTTTGCT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSCDFLTLANAGVQKLHPYQAGKPTSELERELGISDIVKLASNENPLGLSEKVKSALQSEFSELARYPDANGFYLKQALA
DKYNVGLNQVTLGNGSNDLLELVARAFVSAENEVIFAQFAFVVYPIVTQAIGAKAVVVPAKHYGHDLAAMAAAVTDKTKL
IFIANPNNPTGTFLEAADILAFLSKVPAHVLVVLDEAYFEYAAPERRGNAIAWIKDFPNLIVSRTFSKAYGLAGLRVGYS
VSNPQIADILNRVRQPFNCNALALKAAETVLQDDEYLQAGIKLNNAGMADLSAFFSQHNLEYIPSMGNFITVNVGQSGDV
VYQALLHEGVIVRPITGYGLSDHLRISIGLFDENQRFKQALVKVLKLDQK

Sequences:

>Translated_370_residues
MSCDFLTLANAGVQKLHPYQAGKPTSELERELGISDIVKLASNENPLGLSEKVKSALQSEFSELARYPDANGFYLKQALA
DKYNVGLNQVTLGNGSNDLLELVARAFVSAENEVIFAQFAFVVYPIVTQAIGAKAVVVPAKHYGHDLAAMAAAVTDKTKL
IFIANPNNPTGTFLEAADILAFLSKVPAHVLVVLDEAYFEYAAPERRGNAIAWIKDFPNLIVSRTFSKAYGLAGLRVGYS
VSNPQIADILNRVRQPFNCNALALKAAETVLQDDEYLQAGIKLNNAGMADLSAFFSQHNLEYIPSMGNFITVNVGQSGDV
VYQALLHEGVIVRPITGYGLSDHLRISIGLFDENQRFKQALVKVLKLDQK
>Mature_369_residues
SCDFLTLANAGVQKLHPYQAGKPTSELERELGISDIVKLASNENPLGLSEKVKSALQSEFSELARYPDANGFYLKQALAD
KYNVGLNQVTLGNGSNDLLELVARAFVSAENEVIFAQFAFVVYPIVTQAIGAKAVVVPAKHYGHDLAAMAAAVTDKTKLI
FIANPNNPTGTFLEAADILAFLSKVPAHVLVVLDEAYFEYAAPERRGNAIAWIKDFPNLIVSRTFSKAYGLAGLRVGYSV
SNPQIADILNRVRQPFNCNALALKAAETVLQDDEYLQAGIKLNNAGMADLSAFFSQHNLEYIPSMGNFITVNVGQSGDVV
YQALLHEGVIVRPITGYGLSDHLRISIGLFDENQRFKQALVKVLKLDQK

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=374, Percent_Identity=26.4705882352941, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1786816, Length=231, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322075, Length=403, Percent_Identity=24.5657568238213, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40295; Mature: 40163

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCDFLTLANAGVQKLHPYQAGKPTSELERELGISDIVKLASNENPLGLSEKVKSALQSE
CCCCEEECCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
FSELARYPDANGFYLKQALADKYNVGLNQVTLGNGSNDLLELVARAFVSAENEVIFAQFA
HHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEHHHHH
FVVYPIVTQAIGAKAVVVPAKHYGHDLAAMAAAVTDKTKLIFIANPNNPTGTFLEAADIL
HHHHHHHHHHCCCCEEEECHHHHCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
AFLSKVPAHVLVVLDEAYFEYAAPERRGNAIAWIKDFPNLIVSRTFSKAYGLAGLRVGYS
HHHHHCCHHEEEEEHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEECCC
VSNPQIADILNRVRQPFNCNALALKAAETVLQDDEYLQAGIKLNNAGMADLSAFFSQHNL
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCEECCCCHHHHHHHHHHCCC
EYIPSMGNFITVNVGQSGDVVYQALLHEGVIVRPITGYGLSDHLRISIGLFDENQRFKQA
CCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEEECCCHHHHHH
LVKVLKLDQK
HHHHHHCCCC
>Mature Secondary Structure 
SCDFLTLANAGVQKLHPYQAGKPTSELERELGISDIVKLASNENPLGLSEKVKSALQSE
CCCEEECCCCCHHHCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
FSELARYPDANGFYLKQALADKYNVGLNQVTLGNGSNDLLELVARAFVSAENEVIFAQFA
HHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCEEHHHHH
FVVYPIVTQAIGAKAVVVPAKHYGHDLAAMAAAVTDKTKLIFIANPNNPTGTFLEAADIL
HHHHHHHHHHCCCCEEEECHHHHCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHH
AFLSKVPAHVLVVLDEAYFEYAAPERRGNAIAWIKDFPNLIVSRTFSKAYGLAGLRVGYS
HHHHHCCHHEEEEEHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCEEECCC
VSNPQIADILNRVRQPFNCNALALKAAETVLQDDEYLQAGIKLNNAGMADLSAFFSQHNL
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCEECCCCHHHHHHHHHHCCC
EYIPSMGNFITVNVGQSGDVVYQALLHEGVIVRPITGYGLSDHLRISIGLFDENQRFKQA
CCCCCCCCEEEEEECCCCHHHHHHHHHCCEEEEEECCCCCCCCEEEEEEEECCCHHHHHH
LVKVLKLDQK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA