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The map label for this gene is serC [H]

Identifier: 119944872

GI number: 119944872

Start: 1398511

End: 1399599

Strand: Direct

Name: serC [H]

Synonym: Ping_1115

Alternate gene names: 119944872

Gene position: 1398511-1399599 (Clockwise)

Preceding gene: 119944871

Following gene: 119944873

Centisome position: 30.67

GC content: 43.53

Gene sequence:

>1089_bases
ATGAGTAAAATATTTAATTTCTGCGCAGGTCCGGCTATGTTACCTGAAGCCGTTATGGAAAAAGCACAAGAAGAGTTTTG
TAACTGGCAAGGGCTGGGGGTTTCTGTGATGGAAATCAGCCACCGTAGTCCCGAATATATTGAAATGGCCGAGCAAGCTG
AGCAAGATCTGCGTGATTTGTTGGCTGTACCTGATAATTATAAAGTCCTTTTTTGTCATGGTGGTGGACGCGGACAATTT
GCTGCGGTGCCATTAAATCTGCTGGGCGATAAACTGGATGTGGATTATTTAATCAGCGGACAATGGTCAAAGTTGGCGGT
AGATGAAGCGAAAAAACACGCCCGAGTGACCGAAACCAGTGTTCTCAGCGAAACAGCCGAGGGTAAGGTAAGTGTTAAAG
CCGCTGCTGACTGGAACGTTAATGCTGGCGCCGCTTACGTGCATTACTGCCCCAATGAAACAATCGAAGGTATTGAAATT
TTTGAAGTACCTGAAACAGGGGTTGTGCCGCTGGTTGCCGATATGAGTTCAACGATTTTATCCCGTCCAATTGATGTTTC
TAAATTCGGTGTTATTTACGCTGGCGCACAAAAAAATATCGGCCCATCGGGTTTGGCAATCGTGATCGTGCGTGACGATT
TAATCGGCAAAGCACGCAAAGTTATTCCGTCTATTTTTGATTATAAAGTGCAGGCTGATGCCGGATCAATGTTTAATACT
CCGCCAACTTATTCATGGTACCTGGCAGGCCTCGTTTTTAAGTGGTTAAAAGAGCAGGGTGGTTTGGTCGAAATAGAAAA
GAAAAATATAGCAAAAGCCGAGTTACTTTATAATTTTATCGACAGTTCCAAGTTGTATCGCAATAATATCGACAAATCAG
TGCGTAGCCGTATGAATATTCCCTTTCAACTTGCAGATGAAAACTTAAATGCACTTTTTCTAAAAGAGTCTAAAGACGCT
AACCTGCTGACCCTCAAAGGTCATCGGGCAGTCGGTGGAATGCGTGCCAGTATCTACAATGCAATGCCAATTGAAGGTGT
GCAGGCGTTAGTTGATTTTATGGCAAAGTTTGAAGCTAACTACGCATAA

Upstream 100 bases:

>100_bases
ATTTTGTTGGCACTAGCTGTTTCTTCATCTTACATTTAATGCTAGTTTTACCACCCTAAATAATTTAATTCACCCTCTTA
TATTCTAAAGAAGAAAACCG

Downstream 100 bases:

>100_bases
AATTGATTTATAATAAGCACTTAAAAAGTTCCCTAAAACCATCCAGTTTAAACACCCTCAGTAGAGGGGGTGATAATCGG
TTAATACAAATTGCTATTAG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSKIFNFCAGPAMLPEAVMEKAQEEFCNWQGLGVSVMEISHRSPEYIEMAEQAEQDLRDLLAVPDNYKVLFCHGGGRGQF
AAVPLNLLGDKLDVDYLISGQWSKLAVDEAKKHARVTETSVLSETAEGKVSVKAAADWNVNAGAAYVHYCPNETIEGIEI
FEVPETGVVPLVADMSSTILSRPIDVSKFGVIYAGAQKNIGPSGLAIVIVRDDLIGKARKVIPSIFDYKVQADAGSMFNT
PPTYSWYLAGLVFKWLKEQGGLVEIEKKNIAKAELLYNFIDSSKLYRNNIDKSVRSRMNIPFQLADENLNALFLKESKDA
NLLTLKGHRAVGGMRASIYNAMPIEGVQALVDFMAKFEANYA

Sequences:

>Translated_362_residues
MSKIFNFCAGPAMLPEAVMEKAQEEFCNWQGLGVSVMEISHRSPEYIEMAEQAEQDLRDLLAVPDNYKVLFCHGGGRGQF
AAVPLNLLGDKLDVDYLISGQWSKLAVDEAKKHARVTETSVLSETAEGKVSVKAAADWNVNAGAAYVHYCPNETIEGIEI
FEVPETGVVPLVADMSSTILSRPIDVSKFGVIYAGAQKNIGPSGLAIVIVRDDLIGKARKVIPSIFDYKVQADAGSMFNT
PPTYSWYLAGLVFKWLKEQGGLVEIEKKNIAKAELLYNFIDSSKLYRNNIDKSVRSRMNIPFQLADENLNALFLKESKDA
NLLTLKGHRAVGGMRASIYNAMPIEGVQALVDFMAKFEANYA
>Mature_361_residues
SKIFNFCAGPAMLPEAVMEKAQEEFCNWQGLGVSVMEISHRSPEYIEMAEQAEQDLRDLLAVPDNYKVLFCHGGGRGQFA
AVPLNLLGDKLDVDYLISGQWSKLAVDEAKKHARVTETSVLSETAEGKVSVKAAADWNVNAGAAYVHYCPNETIEGIEIF
EVPETGVVPLVADMSSTILSRPIDVSKFGVIYAGAQKNIGPSGLAIVIVRDDLIGKARKVIPSIFDYKVQADAGSMFNTP
PTYSWYLAGLVFKWLKEQGGLVEIEKKNIAKAELLYNFIDSSKLYRNNIDKSVRSRMNIPFQLADENLNALFLKESKDAN
LLTLKGHRAVGGMRASIYNAMPIEGVQALVDFMAKFEANYA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=362, Percent_Identity=46.6850828729282, Blast_Score=345, Evalue=4e-95,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=42.0168067226891, Blast_Score=294, Evalue=7e-80,
Organism=Escherichia coli, GI1787136, Length=365, Percent_Identity=62.4657534246575, Blast_Score=473, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI17506897, Length=359, Percent_Identity=46.2395543175487, Blast_Score=328, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6324758, Length=381, Percent_Identity=35.9580052493438, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=49.0358126721763, Blast_Score=349, Evalue=2e-96,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39842; Mature: 39711

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIFNFCAGPAMLPEAVMEKAQEEFCNWQGLGVSVMEISHRSPEYIEMAEQAEQDLRDL
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LAVPDNYKVLFCHGGGRGQFAAVPLNLLGDKLDVDYLISGQWSKLAVDEAKKHARVTETS
HCCCCCCEEEEEECCCCCCEEEECHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
VLSETAEGKVSVKAAADWNVNAGAAYVHYCPNETIEGIEIFEVPETGVVPLVADMSSTIL
HHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEHHHHHHHHH
SRPIDVSKFGVIYAGAQKNIGPSGLAIVIVRDDLIGKARKVIPSIFDYKVQADAGSMFNT
HCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCEEEEECCCCCCCC
PPTYSWYLAGLVFKWLKEQGGLVEIEKKNIAKAELLYNFIDSSKLYRNNIDKSVRSRMNI
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PFQLADENLNALFLKESKDANLLTLKGHRAVGGMRASIYNAMPIEGVQALVDFMAKFEAN
CEEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCC
YA
CC
>Mature Secondary Structure 
SKIFNFCAGPAMLPEAVMEKAQEEFCNWQGLGVSVMEISHRSPEYIEMAEQAEQDLRDL
CCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
LAVPDNYKVLFCHGGGRGQFAAVPLNLLGDKLDVDYLISGQWSKLAVDEAKKHARVTETS
HCCCCCCEEEEEECCCCCCEEEECHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
VLSETAEGKVSVKAAADWNVNAGAAYVHYCPNETIEGIEIFEVPETGVVPLVADMSSTIL
HHHHCCCCEEEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEHHHHHHHHH
SRPIDVSKFGVIYAGAQKNIGPSGLAIVIVRDDLIGKARKVIPSIFDYKVQADAGSMFNT
HCCCCCCCCEEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCEEEEECCCCCCCC
PPTYSWYLAGLVFKWLKEQGGLVEIEKKNIAKAELLYNFIDSSKLYRNNIDKSVRSRMNI
CCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
PFQLADENLNALFLKESKDANLLTLKGHRAVGGMRASIYNAMPIEGVQALVDFMAKFEAN
CEEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCC
YA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]