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The map label for this gene is icd2 [H]

Identifier: 119944742

GI number: 119944742

Start: 1239038

End: 1241266

Strand: Direct

Name: icd2 [H]

Synonym: Ping_0983

Alternate gene names: 119944742

Gene position: 1239038-1241266 (Clockwise)

Preceding gene: 119944735

Following gene: 119944746

Centisome position: 27.17

GC content: 42.75

Gene sequence:

>2229_bases
ATGACTGATAAATCTGCAAAGATCATCTACACACAGACGGATGAAGCACCCGCACTTGCAACCTATTCTCTACTTCCCAT
TGTTAGTGCCTTTACACAGGCCGCAGATATAACAGTTGAAACGCGCGATATCTCTTTAGCTGCCCGTATTCTGGCTACTT
TTCCTGATAATTTAAGTGCAGAACAAAAACAGGCCGATGCATTGACCGAATTGGGTGAGCTTGCTCAACAACCGCAGGCC
AATATTATTAAATTGCCTAATGTGAGCGCTTCGGTTCCACAGCTTCATGCCGCAATTAAAGAATTACAATCACACGGTTT
TGATATTCCAAACTACCCTGAAGACCCAAAAACCGAAGCAGAAAAAGAAGCAAAAGCCCGTTACGCAAAAGTATTAGGCA
GTGCTGTAAATCCGGTTTTACGTGAAGGTAACTCAGACCGCCGTGTGGCTGATGCGGTTAAACAGTATGCACAGGATCAT
CCTCACCGTATGGGAGCTTGGTCTAAAGAGTCAAAATCACATGTTGCGGATATGTCCGAAGGTGATTTTTATGGCAGCGA
ACAGTCAGTTGTATTAAAGGAAGCTGATGATGTCAAAATTGAATTTACTTCTACTTCCGGTGCAGTCTCAGTATTAAAAG
CATCAACACCCGTATTAAAAGATGAAGTCATTGATGCATCGGTAATGAGCTGTTCTGCATTACGTGATTTTTACGAAACA
CAAATGCAGGATGCCAAAGAGAATAACATTATGCTCTCGTTGCATCTTAAAGCGACCATGATGAAAGTATCCGATCCTGT
TATGTTTGGTCATGCAGTGACGGTTTACTTTAAAGACGTGTTTGCTAAACACGCAGTGCTATTTGCCGAGTTAGGTGTTG
ATCCCCGTAACGGTCTGGGTGATGTTTACAGCAAAATAGCAAATTTACCCGCAGAACAAAAAGAGCAGATAGAAGCGGAT
ATTCAAGAAGCTTATGCAACGGGTCCTGCGCTTGCAATGGTTGATTCAGACAAAGGAATCAGTAATTTACATGTACCAAG
TGATGTGATTATTGATGCCTCTATGCCGGCTGCTATCCGTACTTCAGGGTGCATGTGGGGCTTAGACGGAAAACTTCATG
ATACTAAAGCGATGATTCCAGATCGTTGTTACTCAGGCATTTATCAAGAGACTATCTCTTTCTGTCGTGAACACGGTGCA
TTTGACCCTGCGACTATGGGTAATGTATCTAACGTAGGTTTAATGGCTCAAAAAGCCGAAGAGTACGGCTCGCACGATAA
AACTTTTATTATTAAAGAAGCTGGTAGCGTTAAAGTGATTGATCAAGCGGGCAATACTTTAATGGAACATGCTGTTGAAG
AAGGTGATATCTGGCGCATGTGTCAGGCTAAAGATATTCCAATTCAAGATTGGGTGCGTCTTGCGGTCAGCCGTGCCAGA
GCAACCGGACAACCCGCTATTTTCTGGTTAGATGAAAAACGTGCTCACGATGGGAATCTCATCACTAAAGTAAATCATTA
CTTAAAAGATCACGATACAGATGGTTTGGATATTAGCATTTTATCGCCTATCGACGCGATTAAAATTACCCTGCAGCGTG
TCTCAGAAGGTAAAAATACAATCTCTGTTACAGGGAATGTATTACGTGATTACCTAACCGATCTGTTCCCAATTCTAGAA
CTTGGTACCAGTGCGAAAATGCTTTCAATTGTTCCTCTTCTTGCTGGTGGTGGTTTATTTGAAACAGGTGCTGGTGGCAG
TGCACCTAAACACGTTCAGCAGTTTATTGAAGAAGGGCATTTACGTTGGGATTCGATCGGTGAATTCTTAGCCATTGCTG
TGTCCATTGAAGATATGGCAGAAAAAACAGGCAATAAGAAAGCCCTCGTTCTTGCAGAAACACTGCATGTAGCTAATGGA
AAATTCTTAAAAGAAGACAGATCCCCATCACGTAAAGTCAAAGAAATTGATAACCGTGGTAGCCATTTCTATCTTGCAAT
GTATTGGGCAGAGGCACTTGCAGCACAGTCTAAAGATACTGAACTGCAGGCGAAATTTGCACCCCTTGCCAAAGTACTTA
CTGACAATGAAGAAAAGATTCTGGCTGAGTTAGCTGCAGCGCAGGGTACTCCAGTTGATTTAGGCGGTTACTTCCACACA
GATCCGGTGAAAATGGCAGCAGCAATGCGTCCAAGCACAATATTAAATGCTGCACTGGCAACGCTTTAA

Upstream 100 bases:

>100_bases
TTGTCACCCATGCGTTATAACTAATAAATCTGCTCTACGGTCCATTGTTTTAGTAGATAACTAGCCAATAAACATCTTAA
AACTTGTTAAAGGAATAAAT

Downstream 100 bases:

>100_bases
TTTTAGAATTAGGTTCTGCGAGGGACTTTCTTTAATTAAATGATCAGGGAAATCTGGTTTTGAGGTAAGTTGATATTTTT
ACCCTTTTAAAACGCTCGAT

Product: isocitrate dehydrogenase, NADP-dependent

Products: NA

Alternate protein names: IDH-II; IDP-2; NADP+-specific ICDH 2; Oxalosuccinate decarboxylase 2 [H]

Number of amino acids: Translated: 742; Mature: 741

Protein sequence:

>742_residues
MTDKSAKIIYTQTDEAPALATYSLLPIVSAFTQAADITVETRDISLAARILATFPDNLSAEQKQADALTELGELAQQPQA
NIIKLPNVSASVPQLHAAIKELQSHGFDIPNYPEDPKTEAEKEAKARYAKVLGSAVNPVLREGNSDRRVADAVKQYAQDH
PHRMGAWSKESKSHVADMSEGDFYGSEQSVVLKEADDVKIEFTSTSGAVSVLKASTPVLKDEVIDASVMSCSALRDFYET
QMQDAKENNIMLSLHLKATMMKVSDPVMFGHAVTVYFKDVFAKHAVLFAELGVDPRNGLGDVYSKIANLPAEQKEQIEAD
IQEAYATGPALAMVDSDKGISNLHVPSDVIIDASMPAAIRTSGCMWGLDGKLHDTKAMIPDRCYSGIYQETISFCREHGA
FDPATMGNVSNVGLMAQKAEEYGSHDKTFIIKEAGSVKVIDQAGNTLMEHAVEEGDIWRMCQAKDIPIQDWVRLAVSRAR
ATGQPAIFWLDEKRAHDGNLITKVNHYLKDHDTDGLDISILSPIDAIKITLQRVSEGKNTISVTGNVLRDYLTDLFPILE
LGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFIEEGHLRWDSIGEFLAIAVSIEDMAEKTGNKKALVLAETLHVANG
KFLKEDRSPSRKVKEIDNRGSHFYLAMYWAEALAAQSKDTELQAKFAPLAKVLTDNEEKILAELAAAQGTPVDLGGYFHT
DPVKMAAAMRPSTILNAALATL

Sequences:

>Translated_742_residues
MTDKSAKIIYTQTDEAPALATYSLLPIVSAFTQAADITVETRDISLAARILATFPDNLSAEQKQADALTELGELAQQPQA
NIIKLPNVSASVPQLHAAIKELQSHGFDIPNYPEDPKTEAEKEAKARYAKVLGSAVNPVLREGNSDRRVADAVKQYAQDH
PHRMGAWSKESKSHVADMSEGDFYGSEQSVVLKEADDVKIEFTSTSGAVSVLKASTPVLKDEVIDASVMSCSALRDFYET
QMQDAKENNIMLSLHLKATMMKVSDPVMFGHAVTVYFKDVFAKHAVLFAELGVDPRNGLGDVYSKIANLPAEQKEQIEAD
IQEAYATGPALAMVDSDKGISNLHVPSDVIIDASMPAAIRTSGCMWGLDGKLHDTKAMIPDRCYSGIYQETISFCREHGA
FDPATMGNVSNVGLMAQKAEEYGSHDKTFIIKEAGSVKVIDQAGNTLMEHAVEEGDIWRMCQAKDIPIQDWVRLAVSRAR
ATGQPAIFWLDEKRAHDGNLITKVNHYLKDHDTDGLDISILSPIDAIKITLQRVSEGKNTISVTGNVLRDYLTDLFPILE
LGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFIEEGHLRWDSIGEFLAIAVSIEDMAEKTGNKKALVLAETLHVANG
KFLKEDRSPSRKVKEIDNRGSHFYLAMYWAEALAAQSKDTELQAKFAPLAKVLTDNEEKILAELAAAQGTPVDLGGYFHT
DPVKMAAAMRPSTILNAALATL
>Mature_741_residues
TDKSAKIIYTQTDEAPALATYSLLPIVSAFTQAADITVETRDISLAARILATFPDNLSAEQKQADALTELGELAQQPQAN
IIKLPNVSASVPQLHAAIKELQSHGFDIPNYPEDPKTEAEKEAKARYAKVLGSAVNPVLREGNSDRRVADAVKQYAQDHP
HRMGAWSKESKSHVADMSEGDFYGSEQSVVLKEADDVKIEFTSTSGAVSVLKASTPVLKDEVIDASVMSCSALRDFYETQ
MQDAKENNIMLSLHLKATMMKVSDPVMFGHAVTVYFKDVFAKHAVLFAELGVDPRNGLGDVYSKIANLPAEQKEQIEADI
QEAYATGPALAMVDSDKGISNLHVPSDVIIDASMPAAIRTSGCMWGLDGKLHDTKAMIPDRCYSGIYQETISFCREHGAF
DPATMGNVSNVGLMAQKAEEYGSHDKTFIIKEAGSVKVIDQAGNTLMEHAVEEGDIWRMCQAKDIPIQDWVRLAVSRARA
TGQPAIFWLDEKRAHDGNLITKVNHYLKDHDTDGLDISILSPIDAIKITLQRVSEGKNTISVTGNVLRDYLTDLFPILEL
GTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFIEEGHLRWDSIGEFLAIAVSIEDMAEKTGNKKALVLAETLHVANGK
FLKEDRSPSRKVKEIDNRGSHFYLAMYWAEALAAQSKDTELQAKFAPLAKVLTDNEEKILAELAAAQGTPVDLGGYFHTD
PVKMAAAMRPSTILNAALATL

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 80725; Mature: 80594

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSAKIIYTQTDEAPALATYSLLPIVSAFTQAADITVETRDISLAARILATFPDNLSA
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHCCCCCCH
EQKQADALTELGELAQQPQANIIKLPNVSASVPQLHAAIKELQSHGFDIPNYPEDPKTEA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
EKEAKARYAKVLGSAVNPVLREGNSDRRVADAVKQYAQDHPHRMGAWSKESKSHVADMSE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHCCCCCCCHHHHHCCCCC
GDFYGSEQSVVLKEADDVKIEFTSTSGAVSVLKASTPVLKDEVIDASVMSCSALRDFYET
CCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QMQDAKENNIMLSLHLKATMMKVSDPVMFGHAVTVYFKDVFAKHAVLFAELGVDPRNGLG
HHHCCCCCCEEEEEEEEEEHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DVYSKIANLPAEQKEQIEADIQEAYATGPALAMVDSDKGISNLHVPSDVIIDASMPAAIR
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHH
TSGCMWGLDGKLHDTKAMIPDRCYSGIYQETISFCREHGAFDPATMGNVSNVGLMAQKAE
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHH
EYGSHDKTFIIKEAGSVKVIDQAGNTLMEHAVEEGDIWRMCQAKDIPIQDWVRLAVSRAR
HHCCCCCEEEEECCCCEEEEHHCCHHHHHHHHCCCCEEEHHCCCCCCHHHHHHHHHHHHH
ATGQPAIFWLDEKRAHDGNLITKVNHYLKDHDTDGLDISILSPIDAIKITLQRVSEGKNT
CCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCE
ISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFIEEGH
EEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSIGEFLAIAVSIEDMAEKTGNKKALVLAETLHVANGKFLKEDRSPSRKVKEIDNRG
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHCCC
SHFYLAMYWAEALAAQSKDTELQAKFAPLAKVLTDNEEKILAELAAAQGTPVDLGGYFHT
CEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCEECC
DPVKMAAAMRPSTILNAALATL
CHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
TDKSAKIIYTQTDEAPALATYSLLPIVSAFTQAADITVETRDISLAARILATFPDNLSA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHCCCCCCH
EQKQADALTELGELAQQPQANIIKLPNVSASVPQLHAAIKELQSHGFDIPNYPEDPKTEA
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHH
EKEAKARYAKVLGSAVNPVLREGNSDRRVADAVKQYAQDHPHRMGAWSKESKSHVADMSE
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHCCCCCCCHHHHHCCCCC
GDFYGSEQSVVLKEADDVKIEFTSTSGAVSVLKASTPVLKDEVIDASVMSCSALRDFYET
CCCCCCCCCEEEECCCCEEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QMQDAKENNIMLSLHLKATMMKVSDPVMFGHAVTVYFKDVFAKHAVLFAELGVDPRNGLG
HHHCCCCCCEEEEEEEEEEHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DVYSKIANLPAEQKEQIEADIQEAYATGPALAMVDSDKGISNLHVPSDVIIDASMPAAIR
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCHHHH
TSGCMWGLDGKLHDTKAMIPDRCYSGIYQETISFCREHGAFDPATMGNVSNVGLMAQKAE
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHH
EYGSHDKTFIIKEAGSVKVIDQAGNTLMEHAVEEGDIWRMCQAKDIPIQDWVRLAVSRAR
HHCCCCCEEEEECCCCEEEEHHCCHHHHHHHHCCCCEEEHHCCCCCCHHHHHHHHHHHHH
ATGQPAIFWLDEKRAHDGNLITKVNHYLKDHDTDGLDISILSPIDAIKITLQRVSEGKNT
CCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCE
ISVTGNVLRDYLTDLFPILELGTSAKMLSIVPLLAGGGLFETGAGGSAPKHVQQFIEEGH
EEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCC
LRWDSIGEFLAIAVSIEDMAEKTGNKKALVLAETLHVANGKFLKEDRSPSRKVKEIDNRG
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHCCC
SHFYLAMYWAEALAAQSKDTELQAKFAPLAKVLTDNEEKILAELAAAQGTPVDLGGYFHT
CEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCEECC
DPVKMAAAMRPSTILNAALATL
CHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226630; 1295895 [H]