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The map label for this gene is modF [H]

Identifier: 119944735

GI number: 119944735

Start: 1225549

End: 1226928

Strand: Direct

Name: modF [H]

Synonym: Ping_0976

Alternate gene names: 119944735

Gene position: 1225549-1226928 (Clockwise)

Preceding gene: 119944733

Following gene: 119944742

Centisome position: 26.88

GC content: 36.38

Gene sequence:

>1380_bases
ATGATAAATATTGTAAATTTTGAGCATAACAAGTTAACCATCAAAAACTGGCAACTACGTGAAAATGAAAATTGGTGTGT
ATTAGGCCGTAATGGCTCTGGAAAGCAGTATCTGAATCAGCTTTTAACCGGCGCGCTAGAGCCAACGAGTTTTGAACAAT
TACAATCACCTGATAAAGAGAAAGTAGGGATCATTTCATTTGAAATGCAGCAAGATACCTATGAGCAGACGCTTAAACTA
GAAGCACCAGATGATATCGATGCAGACGATGTGGGCACTAAAGCAAAAAACTTTCTCCCAAAAGATAGATTGAATGATCC
ACTTATTAATGAATTTGGTTTAAGCCACCGACTTGAAACAAGGTATATTCAATTAAGCACAGGTGAAAGTAGAAAGCTTT
TAATTCTACAAGCCATCTTTAGCGGCATTGAGCTTTTAGTCTGCGATAATCCTTTTGACAGCTTAGATAGCGAATCATGT
GAAGCATTGTCCATTGCCTTAGAGCGCTTATCTAAGACAGGTGTGACTGTATTGCTGATGTTAAGTAACCGACAAGATAT
CCCTGTTTGGTGTCACAATATTGCCTTTATTGAACGAGGTCGATTTGATGTGATTGGTAAATTGGACAATATTGACACTA
AAAATCAATTGGATGCTTTATTAAGTCCTGCAACTGATAAAACCAGTTGGCCAGAAAATATGCAAGAATTATCAGATTAT
AAGCATCCATATTTAGTTAAGCTTTCTAAAGGCACTGTTCATTATAATGGTGTCAATGTTTTTGAAAACTTAGATGTTGA
AATAAAACCCTTGCAGCATACTTTGATAACTGGTGCTAACGGCAGTGGAAAATCAACCCTAATGCAGTTAATTACAGGGG
ATTGCCCACAATGTTATAGCAACGATATTCATGTACTTGGATATAAACGCGGTTCCGGTGAGGCTATTTGGGAAATTAAA
AAACAGATGGGTATTGTGAGCTCAGAACTCCATCGACAATACAGAGTAAATGGTGACCTATTAACGGTTGTTCTTTCAGG
GTTTTATGACTCTATTGGTGTTTACCAACAAACAACACCATACCAGATAAATATTGCTCGCCAGTGGTTAGATAAAATAG
GGTTATTAACACACCAAAAGAGTTTATTTCAAAGCTTAAGCTATGGTGAACAACGGCTCGCATTAATTGCGCGAGCGTTA
GTTAAATCGCCTTATTTATTAATTTTAGATGAGCCAACCCAAGGTTTAGATGAACTTAATAGGCATAGAGTACTTAACTT
TTTAGAGCATTTAGCAACACAAAAACACAGTACAATGTTATTAGTAAGCCATCGTAAGGATGAGTTTTTATCCATATTTA
AGCAACATATTAAGCTTTAA

Upstream 100 bases:

>100_bases
TGTGGTGCGTCCATAGTTGTCCAGTCTTCCTCAATCAAATAGTTTGATATAAGATACCAAAGAAAACAAATAACCCCCTT
TAAAAGAAACTGAATACGCT

Downstream 100 bases:

>100_bases
GGCGTGCATTACTATCGAACATACTTATGCAAAGGGTATAAGTATGTGGCCTTTGGCTATTCTATTTTTCGTTATTTTAT
TTGTTATGTTTCACTAATTC

Product: ABC transporter for molybdenum ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MINIVNFEHNKLTIKNWQLRENENWCVLGRNGSGKQYLNQLLTGALEPTSFEQLQSPDKEKVGIISFEMQQDTYEQTLKL
EAPDDIDADDVGTKAKNFLPKDRLNDPLINEFGLSHRLETRYIQLSTGESRKLLILQAIFSGIELLVCDNPFDSLDSESC
EALSIALERLSKTGVTVLLMLSNRQDIPVWCHNIAFIERGRFDVIGKLDNIDTKNQLDALLSPATDKTSWPENMQELSDY
KHPYLVKLSKGTVHYNGVNVFENLDVEIKPLQHTLITGANGSGKSTLMQLITGDCPQCYSNDIHVLGYKRGSGEAIWEIK
KQMGIVSSELHRQYRVNGDLLTVVLSGFYDSIGVYQQTTPYQINIARQWLDKIGLLTHQKSLFQSLSYGEQRLALIARAL
VKSPYLLILDEPTQGLDELNRHRVLNFLEHLATQKHSTMLLVSHRKDEFLSIFKQHIKL

Sequences:

>Translated_459_residues
MINIVNFEHNKLTIKNWQLRENENWCVLGRNGSGKQYLNQLLTGALEPTSFEQLQSPDKEKVGIISFEMQQDTYEQTLKL
EAPDDIDADDVGTKAKNFLPKDRLNDPLINEFGLSHRLETRYIQLSTGESRKLLILQAIFSGIELLVCDNPFDSLDSESC
EALSIALERLSKTGVTVLLMLSNRQDIPVWCHNIAFIERGRFDVIGKLDNIDTKNQLDALLSPATDKTSWPENMQELSDY
KHPYLVKLSKGTVHYNGVNVFENLDVEIKPLQHTLITGANGSGKSTLMQLITGDCPQCYSNDIHVLGYKRGSGEAIWEIK
KQMGIVSSELHRQYRVNGDLLTVVLSGFYDSIGVYQQTTPYQINIARQWLDKIGLLTHQKSLFQSLSYGEQRLALIARAL
VKSPYLLILDEPTQGLDELNRHRVLNFLEHLATQKHSTMLLVSHRKDEFLSIFKQHIKL
>Mature_459_residues
MINIVNFEHNKLTIKNWQLRENENWCVLGRNGSGKQYLNQLLTGALEPTSFEQLQSPDKEKVGIISFEMQQDTYEQTLKL
EAPDDIDADDVGTKAKNFLPKDRLNDPLINEFGLSHRLETRYIQLSTGESRKLLILQAIFSGIELLVCDNPFDSLDSESC
EALSIALERLSKTGVTVLLMLSNRQDIPVWCHNIAFIERGRFDVIGKLDNIDTKNQLDALLSPATDKTSWPENMQELSDY
KHPYLVKLSKGTVHYNGVNVFENLDVEIKPLQHTLITGANGSGKSTLMQLITGDCPQCYSNDIHVLGYKRGSGEAIWEIK
KQMGIVSSELHRQYRVNGDLLTVVLSGFYDSIGVYQQTTPYQINIARQWLDKIGLLTHQKSLFQSLSYGEQRLALIARAL
VKSPYLLILDEPTQGLDELNRHRVLNFLEHLATQKHSTMLLVSHRKDEFLSIFKQHIKL

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI27262626, Length=193, Percent_Identity=28.4974093264249, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI116734710, Length=188, Percent_Identity=30.3191489361702, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786975, Length=465, Percent_Identity=36.5591397849462, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1787029, Length=201, Percent_Identity=28.8557213930348, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789864, Length=208, Percent_Identity=27.8846153846154, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789991, Length=214, Percent_Identity=28.0373831775701, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789873, Length=198, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=492, Percent_Identity=25.8130081300813, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24650855, Length=239, Percent_Identity=28.8702928870293, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24650853, Length=239, Percent_Identity=28.8702928870293, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281362751, Length=247, Percent_Identity=28.7449392712551, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 52211; Mature: 52211

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIVNFEHNKLTIKNWQLRENENWCVLGRNGSGKQYLNQLLTGALEPTSFEQLQSPDKE
CEEEEEECCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCC
KVGIISFEMQQDTYEQTLKLEAPDDIDADDVGTKAKNFLPKDRLNDPLINEFGLSHRLET
CEEEEEEEECCCHHHHEEEECCCCCCCCCCCCCHHHHCCCHHHCCCCCHHHHCCCCCCEE
RYIQLSTGESRKLLILQAIFSGIELLVCDNPFDSLDSESCEALSIALERLSKTGVTVLLM
EEEEEECCCCCEEEHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
LSNRQDIPVWCHNIAFIERGRFDVIGKLDNIDTKNQLDALLSPATDKTSWPENMQELSDY
ECCCCCCCCHHHCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHC
KHPYLVKLSKGTVHYNGVNVFENLDVEIKPLQHTLITGANGSGKSTLMQLITGDCPQCYS
CCCEEEEEECCEEEECCEEEEECCCEEEEECEEEEEECCCCCCHHHHHHHHHCCCCHHHC
NDIHVLGYKRGSGEAIWEIKKQMGIVSSELHRQYRVNGDLLTVVLSGFYDSIGVYQQTTP
CCEEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
YQINIARQWLDKIGLLTHQKSLFQSLSYGEQRLALIARALVKSPYLLILDEPTQGLDELN
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
RHRVLNFLEHLATQKHSTMLLVSHRKDEFLSIFKQHIKL
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MINIVNFEHNKLTIKNWQLRENENWCVLGRNGSGKQYLNQLLTGALEPTSFEQLQSPDKE
CEEEEEECCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHCCCCCC
KVGIISFEMQQDTYEQTLKLEAPDDIDADDVGTKAKNFLPKDRLNDPLINEFGLSHRLET
CEEEEEEEECCCHHHHEEEECCCCCCCCCCCCCHHHHCCCHHHCCCCCHHHHCCCCCCEE
RYIQLSTGESRKLLILQAIFSGIELLVCDNPFDSLDSESCEALSIALERLSKTGVTVLLM
EEEEEECCCCCEEEHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEE
LSNRQDIPVWCHNIAFIERGRFDVIGKLDNIDTKNQLDALLSPATDKTSWPENMQELSDY
ECCCCCCCCHHHCEEEEECCCEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHC
KHPYLVKLSKGTVHYNGVNVFENLDVEIKPLQHTLITGANGSGKSTLMQLITGDCPQCYS
CCCEEEEEECCEEEECCEEEEECCCEEEEECEEEEEECCCCCCHHHHHHHHHCCCCHHHC
NDIHVLGYKRGSGEAIWEIKKQMGIVSSELHRQYRVNGDLLTVVLSGFYDSIGVYQQTTP
CCEEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
YQINIARQWLDKIGLLTHQKSLFQSLSYGEQRLALIARALVKSPYLLILDEPTQGLDELN
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHH
RHRVLNFLEHLATQKHSTMLLVSHRKDEFLSIFKQHIKL
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]