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The map label for this gene is pgm [H]

Identifier: 119944640

GI number: 119944640

Start: 1098302

End: 1099954

Strand: Direct

Name: pgm [H]

Synonym: Ping_0879

Alternate gene names: 119944640

Gene position: 1098302-1099954 (Clockwise)

Preceding gene: 119944639

Following gene: 119944641

Centisome position: 24.09

GC content: 42.89

Gene sequence:

>1653_bases
ATGGCAATTCATCCCCGCGCAGGGCAACCTGCACAGGTTCAAGATTTAGTTAATATACCAAAATTGATTTCAGCGTATTA
TATTAACCTTCCCGATGTGAGTGTTGCAAGCGAGCAAGTTGCATTTGGTACCTCCGGGCATCGTGGCAGTTCATTTAACA
ATGCATTCACTGAGCTGCATATCTTAGCGATTAGCCAGGCATTAGCAGAATACCGCATTCAGCAAGGTTATACTGGGCCT
CTGTTTATTGGTAAAGATACCCATGCGTTATCTGAGCCTGCTTTTGTTTCTGCGGTGCAGGTTTTAGTTGCCAATAATAT
TAAAGTAATTGTACAAGCTGGCGGTGGTTACACGCCAACACCCGTTATTTCACATGCCATTCTGCAATACAATAAAGCCA
ATCCAGACAATTTAGCTGATGGTATTGTGATCACTCCCTCGCATAATCCACCGGAAGATGGCGGGTTTAAGTACAATCCA
CCCAACGGCGGTCCTGCAGACAGTGATGTGACAAAAATTATCCAAGACAGAGCCAATGAAATTTTAAATGATAATTTTGA
TGATATCGAACAATGGGATTTCAGCGAGGCAATGGCATCAGACTTGGTTGAAGAATACGATTATATTCAACCCTATGTTG
ATGATTTGAAAAATGTCCTTGATTTGGATGCTATTGCAAAAGCGGGGATCAAAATTGGTGTGGATACGCTAGGGGGTTCT
GGGGTTGCATACTGGCCTGTGATTGCGAAAACCTATGGTTTGAATATTGAAGTTGTCAACGATCGTGTCGATCCTACTTT
CTCTTTTATGACCTTAGATAAAGATGGCAAAATCCGCATGGATTGTTCTTCGCCTTATGCCATGGCGGGTTTAATTAAAT
TAAAAGACAAATTTGATGTTGCTATCGCTAACGACCCTGACTACGACCGTCACGGTATTGTTACCAAAAGCTCCGGTTTA
TTAAACCCAAATCATTACCTTGCCGTGGCTATTAATTACTTATTCACTCACCGCACTGGCTGGTCTGAGAATGCAAAAGT
AGGTAAAACACTAGTATCGAGCTCAATGATTGATCGTGTTGTTGCACAATTAGGTCGTCAGATGTCTGAAGTGCCCGTCG
GTTTTAAATGGTTTGTTGATGGTTTATTCGATGGCTCATTTGGTTTTGGTGGCGAAGAGAGTGCCGGTGCTTCTTTTCTG
CGCAAAGATGGTACGGTATGGACGACGGATAAAGACGGTATTATTTTGGCGTTATTAGCCGCGGAAATTATTGCTGTCAC
AGGTCGTGATCCTGGTGAGCATTATGCTGAATTTACAGAAAAATTTGGTTCACCTGTTTATACGCGTTTTGATGCGCCCG
CAAGCGCTGAACAGAAGAAAGTATTAGCCAACTTAACTGCGGATATGGTCGAAGCAGAAACATTAGCCGGTGAAAAAATT
ACCGCCAAATTAACCCACGCTTCAGGTAATGGCGCTGCTATTGGCGGTTTAAAGGTGACCACTGAAAACGGTTGGTTTGC
CGCGCGCCCATCGGGTACGGAAAACATCTACAAAATTTACTCAGAGTCATTTATTGGTGAAGAGCATATTGCATTGATTC
AAAAAGAAGCACAGGTAATTGTTGCCCAAGCCTTTGCCAAAGCCGGATTATAA

Upstream 100 bases:

>100_bases
GTTTGACGAACTAGGGTGAAGCAGTCTAGTCAAACGGTCGAAAATACATTTACGAACTTGTAACCACATTTTATTTAACC
TAATCGAGGTAGACATTATT

Downstream 100 bases:

>100_bases
TCCACTCTTTTACAGTGCATGATCAGCTTAAATAAAGTGAAATATTTTTTAAAAACGAGGGTTATCACCCTCGTTTTTTG
CTTTTAATTTTGTCATCTCA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MAIHPRAGQPAQVQDLVNIPKLISAYYINLPDVSVASEQVAFGTSGHRGSSFNNAFTELHILAISQALAEYRIQQGYTGP
LFIGKDTHALSEPAFVSAVQVLVANNIKVIVQAGGGYTPTPVISHAILQYNKANPDNLADGIVITPSHNPPEDGGFKYNP
PNGGPADSDVTKIIQDRANEILNDNFDDIEQWDFSEAMASDLVEEYDYIQPYVDDLKNVLDLDAIAKAGIKIGVDTLGGS
GVAYWPVIAKTYGLNIEVVNDRVDPTFSFMTLDKDGKIRMDCSSPYAMAGLIKLKDKFDVAIANDPDYDRHGIVTKSSGL
LNPNHYLAVAINYLFTHRTGWSENAKVGKTLVSSSMIDRVVAQLGRQMSEVPVGFKWFVDGLFDGSFGFGGEESAGASFL
RKDGTVWTTDKDGIILALLAAEIIAVTGRDPGEHYAEFTEKFGSPVYTRFDAPASAEQKKVLANLTADMVEAETLAGEKI
TAKLTHASGNGAAIGGLKVTTENGWFAARPSGTENIYKIYSESFIGEEHIALIQKEAQVIVAQAFAKAGL

Sequences:

>Translated_550_residues
MAIHPRAGQPAQVQDLVNIPKLISAYYINLPDVSVASEQVAFGTSGHRGSSFNNAFTELHILAISQALAEYRIQQGYTGP
LFIGKDTHALSEPAFVSAVQVLVANNIKVIVQAGGGYTPTPVISHAILQYNKANPDNLADGIVITPSHNPPEDGGFKYNP
PNGGPADSDVTKIIQDRANEILNDNFDDIEQWDFSEAMASDLVEEYDYIQPYVDDLKNVLDLDAIAKAGIKIGVDTLGGS
GVAYWPVIAKTYGLNIEVVNDRVDPTFSFMTLDKDGKIRMDCSSPYAMAGLIKLKDKFDVAIANDPDYDRHGIVTKSSGL
LNPNHYLAVAINYLFTHRTGWSENAKVGKTLVSSSMIDRVVAQLGRQMSEVPVGFKWFVDGLFDGSFGFGGEESAGASFL
RKDGTVWTTDKDGIILALLAAEIIAVTGRDPGEHYAEFTEKFGSPVYTRFDAPASAEQKKVLANLTADMVEAETLAGEKI
TAKLTHASGNGAAIGGLKVTTENGWFAARPSGTENIYKIYSESFIGEEHIALIQKEAQVIVAQAFAKAGL
>Mature_549_residues
AIHPRAGQPAQVQDLVNIPKLISAYYINLPDVSVASEQVAFGTSGHRGSSFNNAFTELHILAISQALAEYRIQQGYTGPL
FIGKDTHALSEPAFVSAVQVLVANNIKVIVQAGGGYTPTPVISHAILQYNKANPDNLADGIVITPSHNPPEDGGFKYNPP
NGGPADSDVTKIIQDRANEILNDNFDDIEQWDFSEAMASDLVEEYDYIQPYVDDLKNVLDLDAIAKAGIKIGVDTLGGSG
VAYWPVIAKTYGLNIEVVNDRVDPTFSFMTLDKDGKIRMDCSSPYAMAGLIKLKDKFDVAIANDPDYDRHGIVTKSSGLL
NPNHYLAVAINYLFTHRTGWSENAKVGKTLVSSSMIDRVVAQLGRQMSEVPVGFKWFVDGLFDGSFGFGGEESAGASFLR
KDGTVWTTDKDGIILALLAAEIIAVTGRDPGEHYAEFTEKFGSPVYTRFDAPASAEQKKVLANLTADMVEAETLAGEKIT
AKLTHASGNGAAIGGLKVTTENGWFAARPSGTENIYKIYSESFIGEEHIALIQKEAQVIVAQAFAKAGL

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=549, Percent_Identity=25.1366120218579, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI133922562, Length=404, Percent_Identity=26.2376237623762, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI21361621, Length=507, Percent_Identity=24.8520710059172, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1786904, Length=548, Percent_Identity=64.051094890511, Blast_Score=722, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=492, Percent_Identity=26.0162601626016, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322722, Length=487, Percent_Identity=28.1314168377823, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6323752, Length=467, Percent_Identity=27.8372591006424, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17864244, Length=401, Percent_Identity=26.1845386533666, Blast_Score=93, Evalue=6e-19,
Organism=Drosophila melanogaster, GI20129809, Length=408, Percent_Identity=26.2254901960784, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24651977, Length=408, Percent_Identity=26.2254901960784, Blast_Score=76, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59289; Mature: 59158

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHPRAGQPAQVQDLVNIPKLISAYYINLPDVSVASEQVAFGTSGHRGSSFNNAFTELH
CCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHH
ILAISQALAEYRIQQGYTGPLFIGKDTHALSEPAFVSAVQVLVANNIKVIVQAGGGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCH
PVISHAILQYNKANPDNLADGIVITPSHNPPEDGGFKYNPPNGGPADSDVTKIIQDRANE
HHHHHHHHHCCCCCCCHHCCCEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
ILNDNFDDIEQWDFSEAMASDLVEEYDYIQPYVDDLKNVLDLDAIAKAGIKIGVDTLGGS
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
GVAYWPVIAKTYGLNIEVVNDRVDPTFSFMTLDKDGKIRMDCSSPYAMAGLIKLKDKFDV
CEEEHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHEEEEECCCEEE
AIANDPDYDRHGIVTKSSGLLNPNHYLAVAINYLFTHRTGWSENAKVGKTLVSSSMIDRV
EECCCCCCCCCCEEECCCCCCCCCCEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VAQLGRQMSEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRKDGTVWTTDKDGIILALLA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEHHHHH
AEIIAVTGRDPGEHYAEFTEKFGSPVYTRFDAPASAEQKKVLANLTADMVEAETLAGEKI
HHHHEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TAKLTHASGNGAAIGGLKVTTENGWFAARPSGTENIYKIYSESFIGEEHIALIQKEAQVI
EEEEEECCCCCEEECCEEEEECCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
VAQAFAKAGL
HHHHHHHHCC
>Mature Secondary Structure 
AIHPRAGQPAQVQDLVNIPKLISAYYINLPDVSVASEQVAFGTSGHRGSSFNNAFTELH
CCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEECCCCCCCCCCCHHHHHHH
ILAISQALAEYRIQQGYTGPLFIGKDTHALSEPAFVSAVQVLVANNIKVIVQAGGGYTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCH
PVISHAILQYNKANPDNLADGIVITPSHNPPEDGGFKYNPPNGGPADSDVTKIIQDRANE
HHHHHHHHHCCCCCCCHHCCCEEECCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHH
ILNDNFDDIEQWDFSEAMASDLVEEYDYIQPYVDDLKNVLDLDAIAKAGIKIGVDTLGGS
HHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
GVAYWPVIAKTYGLNIEVVNDRVDPTFSFMTLDKDGKIRMDCSSPYAMAGLIKLKDKFDV
CEEEHHHHHHHHCCEEEEECCCCCCCEEEEEECCCCCEEEECCCCCHHHEEEEECCCEEE
AIANDPDYDRHGIVTKSSGLLNPNHYLAVAINYLFTHRTGWSENAKVGKTLVSSSMIDRV
EECCCCCCCCCCEEECCCCCCCCCCEEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VAQLGRQMSEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRKDGTVWTTDKDGIILALLA
HHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEHHHHH
AEIIAVTGRDPGEHYAEFTEKFGSPVYTRFDAPASAEQKKVLANLTADMVEAETLAGEKI
HHHHEECCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TAKLTHASGNGAAIGGLKVTTENGWFAARPSGTENIYKIYSESFIGEEHIALIQKEAQVI
EEEEEECCCCCEEECCEEEEECCCEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
VAQAFAKAGL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]