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The map label for this gene is seqA [H]

Identifier: 119944639

GI number: 119944639

Start: 1097181

End: 1097804

Strand: Direct

Name: seqA [H]

Synonym: Ping_0878

Alternate gene names: 119944639

Gene position: 1097181-1097804 (Clockwise)

Preceding gene: 119944633

Following gene: 119944640

Centisome position: 24.06

GC content: 40.87

Gene sequence:

>624_bases
ATGAAAAATATAGAGATAGAAGATGACCTTTATAAATATATTTTGGCTAATATAGAAGCCTTTGGAGAAACACCCTCGCA
GATTCTGCGCAGATTGTTATCTTTACCGAATGCATCCCCAGACAATGCAACCCCAATTACCTCATCCGTAACGCCAAGCG
CTCCCCGTCAAGAAGCCGTTAATGATGAGTCCTCTGTTTTTGAGGCGGTCACGCCTAAGGTGCTTGATCGTGCGAATATT
TCATTGCCAGAGCCCCTTGCTCACGGTGTTAATGCTTTATTTGATAGCGAGGTATTTAAAACAGAAGCCGTTGTGACTAA
TAAATTTATGATGTTGTTGGCGACTATGTATTATGAAAATAAAAATGCATTTGAAGACGCTGCGGATAAAACCAAGGGAC
GTACCCGGGATTATCTGGGGCAGAATTTAAATGCTTTATTGGCAGCGGATAGCGAGGAAGAGCAGAACTTTTTTAAAGCC
AGCAAACCTCGTAACATTCCCCATACGCCATTTTGGGTTATAACCAATGCAAACACGGGGAGGAAACGTATTATTATTAC
CCAAATGATGGCATCAATGGGATACCCCCATTATTTAATTGAACGTATAAAAGAAGAAATTTAG

Upstream 100 bases:

>100_bases
TGATTTTTTTGAGTAGTTTTTTTAATTTTCAGATTGAAATAGAATAGAATAGAATAAAGCAAAATAACTCGTGAAGTGGT
GAATATCGCATGGTGAAAGA

Downstream 100 bases:

>100_bases
TAAGGGTTAATGTTATTTTTTGACGGACCACAGTGAAGTAGTTTAGCCAAACCGTTGAAAATGTTTTGCGAGTGCTTTGA
ATATATTTACGAATTTGTAA

Product: regulatory protein for replication initiation in SeqA family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLPNASPDNATPITSSVTPSAPRQEAVNDESSVFEAVTPKVLDRANI
SLPEPLAHGVNALFDSEVFKTEAVVTNKFMMLLATMYYENKNAFEDAADKTKGRTRDYLGQNLNALLAADSEEEQNFFKA
SKPRNIPHTPFWVITNANTGRKRIIITQMMASMGYPHYLIERIKEEI

Sequences:

>Translated_207_residues
MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLPNASPDNATPITSSVTPSAPRQEAVNDESSVFEAVTPKVLDRANI
SLPEPLAHGVNALFDSEVFKTEAVVTNKFMMLLATMYYENKNAFEDAADKTKGRTRDYLGQNLNALLAADSEEEQNFFKA
SKPRNIPHTPFWVITNANTGRKRIIITQMMASMGYPHYLIERIKEEI
>Mature_207_residues
MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLPNASPDNATPITSSVTPSAPRQEAVNDESSVFEAVTPKVLDRANI
SLPEPLAHGVNALFDSEVFKTEAVVTNKFMMLLATMYYENKNAFEDAADKTKGRTRDYLGQNLNALLAADSEEEQNFFKA
SKPRNIPHTPFWVITNANTGRKRIIITQMMASMGYPHYLIERIKEEI

Specific function: Negative regulator of replication initiation. Required for sequestration, a process that blocks secondary initiation events. Could block the allosteric transition of dnaA from an inactive form to an active form [H]

COG id: COG3057

COG function: function code L; Negative regulator of replication initiationR

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786903, Length=203, Percent_Identity=34.4827586206897, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005621
- InterPro:   IPR010985 [H]

Pfam domain/function: PF03925 SeqA [H]

EC number: NA

Molecular weight: Translated: 23300; Mature: 23300

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLPNASPDNATPITSSVTPSAPRQEAV
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHC
NDESSVFEAVTPKVLDRANISLPEPLAHGVNALFDSEVFKTEAVVTNKFMMLLATMYYEN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNAFEDAADKTKGRTRDYLGQNLNALLAADSEEEQNFFKASKPRNIPHTPFWVITNANTG
CCHHHHHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEEEECCCCC
RKRIIITQMMASMGYPHYLIERIKEEI
CHHHHHHHHHHHCCCHHHHHHHHHHHC
>Mature Secondary Structure
MKNIEIEDDLYKYILANIEAFGETPSQILRRLLSLPNASPDNATPITSSVTPSAPRQEAV
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHC
NDESSVFEAVTPKVLDRANISLPEPLAHGVNALFDSEVFKTEAVVTNKFMMLLATMYYEN
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNAFEDAADKTKGRTRDYLGQNLNALLAADSEEEQNFFKASKPRNIPHTPFWVITNANTG
CCHHHHHHHHHCCCCHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEEEECCCCC
RKRIIITQMMASMGYPHYLIERIKEEI
CHHHHHHHHHHHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]