Click here to switch to the map view.

The map label for this gene is malP [H]

Identifier: 119944641

GI number: 119944641

Start: 1100853

End: 1103357

Strand: Direct

Name: malP [H]

Synonym: Ping_0880

Alternate gene names: 119944641

Gene position: 1100853-1103357 (Clockwise)

Preceding gene: 119944640

Following gene: 119944642

Centisome position: 24.14

GC content: 39.92

Gene sequence:

>2505_bases
ATGACTAAGAAACAGGCAGCAAAAAAAACAATCATTAAAAATAAATCAGCTGAAATAGTGCCAGCCGTAGCCTGCACAAC
AAAGCAAATGCGACAAGCTATTCTGGATCGTCTGCATAAAAGTTTAGCGACAGAAGAAAGCAAGGCAAATAACAAAGCGT
GGTGGAATGCAACTTGTTACGCTGTGAATGAATTACTTTTTGAAAAATTAACAGATACACAAAAGAGTCACTCAGGGCAT
GATACCCGGGCTGTCAATTACCTGTCACTTGAATTTTTGATGGGCCGTCTGCTTTCAAATAACTTACATAACCTGGAATT
ATTCAATGTAGCACAGGATGCATTAAAAGGTTTAGGCAAAGACTTATATGAAATTTGCGAGGAAGAGCCGGATATGGCCC
TCGGTAATGGGGGACTTGGCCGTTTAGCTGCGTGTTTTATTGATTCTTTAGCAACATTAGGCTACCCGGCAATTGGCTAC
GGTATCCATTATGAAAATGGTCTCTTTGCTCAATCATTCCAAGACGGCCGTCAAATTGAACGCCCTGATACATGGCGTGA
ATACGGTAATCCTTGGGAAATTTGTCGCCCTGAATCTATTCAGCATGTGCCATTATATGGTTACGTTGAAACCGTTATTG
ATGAAAACGGTATCTCACATAAAGTTTGGCATGCGGGTCAAAAACTTAAAGGCGTACCATGGGATGTGCCCATTGTGGGT
TATGGTGCTAAAACTGTCAATATTCTACGTTTATGGGAAAGCCGTGCCGATGAAGCATTTGACTGGGATGTCTTTAATGC
CGGTGGTTATGTTGATGCGCAAGTTGAAAAATCAAAAGCTGAGACAATCTCAAAAGTATTATACCCAAATGACTCAACAG
ATGAAGGGAAAGAATTACGCTTAATTCAACAATACTTTTTCTGTGCATGTTCAGTTAAAGATATTTTACGTCGCTTTAGA
CGTGCAGGAAATAAGTGGCCAATATTAGCTGAAAAAGTGGCAATTCAATTAAATGATACCCATCCAACCATCGCCATTCC
CGAGTTAATGCGTATTCTGGTTGATGAAGAGCGTCTTGACTGGAATTTTGCATGGTCACTTTGTGAGAAGATTTTTTCTT
ACACAAACCATACTTTATTGCCAGAGGCGTTAGAAAAATGGTCCGTCGCATTATTTGAAAAAGTATTACCTCGCCATTTA
GAAATTATTTATGAAATTAACCGTCGTTTTCTTGAAACAGTTGAACAAAAATGGCCTGGTGATAACGACATAAAAGCTAA
ATTATCTATTGTTGAGGAAGGTTCGCAGCGCATGGTCCGCATGGCTAATTTGTGTGTTGTAACCTCTCACAAAGTTAATG
GCGTTGCAGCGGTTCATTCTGAATTGGTGAAAACAGATTTGTTCCCTGAATTTGATCAACTGTACCCGACTAAATTAATT
AATGTTACTAACGGTATTACTCCACGTCGTTGGTTAAAAGCTTGTAATCCCGCACTTGCTGCATTATATGATGAAACGGT
GGGTAAAGATTGGGTAGTAAATCTTGATAAATTAAAAGATGCATTACCAAAAGCGACTGACACTGTCTTCCAAAAGCGCT
TTATGGAGATTAAACGCGACAATAAAGTTGAGTTAGTTAACATCATTAAAGACTTGACCGGTATTGAAGTTTCTGCAGAT
GCCATTTTTGACATTCAAATTAAACGTCTGCACGAATACAAACGTCAGCAGTTAAACCTGATTCATATTTTAACCTTGTA
CAGGCGTTTATTGGATAATCCAGATTACGATATGGTTCCGCGGGTTTTCTTATTTGGTGCAAAAGCCGCGCCTGGTTACC
ATATGGCAAAACAGATCATTTATGCATTGAACAAAGTTGCAGAGAAAGTAAACAGTGATAAACGTATCAAAGGTAAGCTG
AAAGTTGTTTTCTTACCAAATTACCGTGTCTCACTTGCTGAAAAAATGTTCCCGGCAGCCGACATATCTGAACAGATTTC
AACGGCAGGTTTGGAAGCTTCCGGTACAGGTAACATGAAATTTGCGCTTAATGGTGCCTTAACCGTCGGTACTATGGATG
GTGCAAATATTGAAATGGCCGAGGAGATCGGTGCTGAGCACATGTTTATTTTCGGTTTAAGTGTTGCTGAAGTTAAAGAG
CTGAAAACAGCGGGTTACAACCCTTACGATTATTATTACAATAATCCTGAGCTGAAAGCGGTGCTTGATTGGTTAGACAC
TGATTTCTTTACACCGGGACAGCCGGGCGCGTTATCCGATATCAAACGCAGCTTGCTTGAATACGGTGATGAGTACCTTT
GTTTAGCTGATTATGAGTCTTACTGTAAAGCTCACGACGCAATTGATACAACCTACCGAAATAAAGCCTTATGGGCCGAA
AAAGCGATTAGAAACTCCGCCGCAATGGGTAAATTTAATTCTGATCGATCCATTGAGGACTATGTAGAAAATGTTTGGCA
TTTGAAAAAATACCCGTTAGCGTGA

Upstream 100 bases:

>100_bases
TTACTTATAAGAATGGTAGGAATATTATATGCCAACTAAAACGAACAAGAAAAAAAACACAATAAAAGCGGATCTAAAAG
CGGCAGTAGAGGAAAAAAAA

Downstream 100 bases:

>100_bases
TCTAGAAGCTTAATTAATTAAAAGGCGATATTCTTATATCGCCTTTTTTTTACCTGATTAGAAGGGGAAATAACTAATAT
CAACGCCTTTCAAATTTGTT

Product: glycogen/starch/alpha-glucan phosphorylases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 834; Mature: 833

Protein sequence:

>834_residues
MTKKQAAKKTIIKNKSAEIVPAVACTTKQMRQAILDRLHKSLATEESKANNKAWWNATCYAVNELLFEKLTDTQKSHSGH
DTRAVNYLSLEFLMGRLLSNNLHNLELFNVAQDALKGLGKDLYEICEEEPDMALGNGGLGRLAACFIDSLATLGYPAIGY
GIHYENGLFAQSFQDGRQIERPDTWREYGNPWEICRPESIQHVPLYGYVETVIDENGISHKVWHAGQKLKGVPWDVPIVG
YGAKTVNILRLWESRADEAFDWDVFNAGGYVDAQVEKSKAETISKVLYPNDSTDEGKELRLIQQYFFCACSVKDILRRFR
RAGNKWPILAEKVAIQLNDTHPTIAIPELMRILVDEERLDWNFAWSLCEKIFSYTNHTLLPEALEKWSVALFEKVLPRHL
EIIYEINRRFLETVEQKWPGDNDIKAKLSIVEEGSQRMVRMANLCVVTSHKVNGVAAVHSELVKTDLFPEFDQLYPTKLI
NVTNGITPRRWLKACNPALAALYDETVGKDWVVNLDKLKDALPKATDTVFQKRFMEIKRDNKVELVNIIKDLTGIEVSAD
AIFDIQIKRLHEYKRQQLNLIHILTLYRRLLDNPDYDMVPRVFLFGAKAAPGYHMAKQIIYALNKVAEKVNSDKRIKGKL
KVVFLPNYRVSLAEKMFPAADISEQISTAGLEASGTGNMKFALNGALTVGTMDGANIEMAEEIGAEHMFIFGLSVAEVKE
LKTAGYNPYDYYYNNPELKAVLDWLDTDFFTPGQPGALSDIKRSLLEYGDEYLCLADYESYCKAHDAIDTTYRNKALWAE
KAIRNSAAMGKFNSDRSIEDYVENVWHLKKYPLA

Sequences:

>Translated_834_residues
MTKKQAAKKTIIKNKSAEIVPAVACTTKQMRQAILDRLHKSLATEESKANNKAWWNATCYAVNELLFEKLTDTQKSHSGH
DTRAVNYLSLEFLMGRLLSNNLHNLELFNVAQDALKGLGKDLYEICEEEPDMALGNGGLGRLAACFIDSLATLGYPAIGY
GIHYENGLFAQSFQDGRQIERPDTWREYGNPWEICRPESIQHVPLYGYVETVIDENGISHKVWHAGQKLKGVPWDVPIVG
YGAKTVNILRLWESRADEAFDWDVFNAGGYVDAQVEKSKAETISKVLYPNDSTDEGKELRLIQQYFFCACSVKDILRRFR
RAGNKWPILAEKVAIQLNDTHPTIAIPELMRILVDEERLDWNFAWSLCEKIFSYTNHTLLPEALEKWSVALFEKVLPRHL
EIIYEINRRFLETVEQKWPGDNDIKAKLSIVEEGSQRMVRMANLCVVTSHKVNGVAAVHSELVKTDLFPEFDQLYPTKLI
NVTNGITPRRWLKACNPALAALYDETVGKDWVVNLDKLKDALPKATDTVFQKRFMEIKRDNKVELVNIIKDLTGIEVSAD
AIFDIQIKRLHEYKRQQLNLIHILTLYRRLLDNPDYDMVPRVFLFGAKAAPGYHMAKQIIYALNKVAEKVNSDKRIKGKL
KVVFLPNYRVSLAEKMFPAADISEQISTAGLEASGTGNMKFALNGALTVGTMDGANIEMAEEIGAEHMFIFGLSVAEVKE
LKTAGYNPYDYYYNNPELKAVLDWLDTDFFTPGQPGALSDIKRSLLEYGDEYLCLADYESYCKAHDAIDTTYRNKALWAE
KAIRNSAAMGKFNSDRSIEDYVENVWHLKKYPLA
>Mature_833_residues
TKKQAAKKTIIKNKSAEIVPAVACTTKQMRQAILDRLHKSLATEESKANNKAWWNATCYAVNELLFEKLTDTQKSHSGHD
TRAVNYLSLEFLMGRLLSNNLHNLELFNVAQDALKGLGKDLYEICEEEPDMALGNGGLGRLAACFIDSLATLGYPAIGYG
IHYENGLFAQSFQDGRQIERPDTWREYGNPWEICRPESIQHVPLYGYVETVIDENGISHKVWHAGQKLKGVPWDVPIVGY
GAKTVNILRLWESRADEAFDWDVFNAGGYVDAQVEKSKAETISKVLYPNDSTDEGKELRLIQQYFFCACSVKDILRRFRR
AGNKWPILAEKVAIQLNDTHPTIAIPELMRILVDEERLDWNFAWSLCEKIFSYTNHTLLPEALEKWSVALFEKVLPRHLE
IIYEINRRFLETVEQKWPGDNDIKAKLSIVEEGSQRMVRMANLCVVTSHKVNGVAAVHSELVKTDLFPEFDQLYPTKLIN
VTNGITPRRWLKACNPALAALYDETVGKDWVVNLDKLKDALPKATDTVFQKRFMEIKRDNKVELVNIIKDLTGIEVSADA
IFDIQIKRLHEYKRQQLNLIHILTLYRRLLDNPDYDMVPRVFLFGAKAAPGYHMAKQIIYALNKVAEKVNSDKRIKGKLK
VVFLPNYRVSLAEKMFPAADISEQISTAGLEASGTGNMKFALNGALTVGTMDGANIEMAEEIGAEHMFIFGLSVAEVKEL
KTAGYNPYDYYYNNPELKAVLDWLDTDFFTPGQPGALSDIKRSLLEYGDEYLCLADYESYCKAHDAIDTTYRNKALWAEK
AIRNSAAMGKFNSDRSIEDYVENVWHLKKYPLA

Specific function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties [

COG id: COG0058

COG function: function code G; Glucan phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycogen phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI71037379, Length=809, Percent_Identity=48.4548825710754, Blast_Score=753, Evalue=0.0,
Organism=Homo sapiens, GI21361370, Length=806, Percent_Identity=48.6352357320099, Blast_Score=753, Evalue=0.0,
Organism=Homo sapiens, GI5032009, Length=797, Percent_Identity=48.5570890840652, Blast_Score=751, Evalue=0.0,
Organism=Homo sapiens, GI255653002, Length=695, Percent_Identity=50.3597122302158, Blast_Score=718, Evalue=0.0,
Organism=Homo sapiens, GI257900462, Length=659, Percent_Identity=49.3171471927162, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI48994936, Length=809, Percent_Identity=50.8034610630408, Blast_Score=805, Evalue=0.0,
Organism=Escherichia coli, GI2367228, Length=805, Percent_Identity=45.8385093167702, Blast_Score=738, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32566204, Length=813, Percent_Identity=47.7244772447724, Blast_Score=780, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17564550, Length=813, Percent_Identity=47.7244772447724, Blast_Score=780, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325418, Length=834, Percent_Identity=45.2038369304556, Blast_Score=682, Evalue=0.0,
Organism=Drosophila melanogaster, GI78706832, Length=797, Percent_Identity=49.5608531994981, Blast_Score=773, Evalue=0.0,
Organism=Drosophila melanogaster, GI24581010, Length=797, Percent_Identity=49.5608531994981, Blast_Score=773, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011833
- InterPro:   IPR000811 [H]

Pfam domain/function: PF00343 Phosphorylase [H]

EC number: =2.4.1.1 [H]

Molecular weight: Translated: 94790; Mature: 94659

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00102 PHOSPHORYLASE ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKQAAKKTIIKNKSAEIVPAVACTTKQMRQAILDRLHKSLATEESKANNKAWWNATCY
CCCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AVNELLFEKLTDTQKSHSGHDTRAVNYLSLEFLMGRLLSNNLHNLELFNVAQDALKGLGK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCH
DLYEICEEEPDMALGNGGLGRLAACFIDSLATLGYPAIGYGIHYENGLFAQSFQDGRQIE
HHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHCCCEEECCCCCHHHHHCCCCCC
RPDTWREYGNPWEICRPESIQHVPLYGYVETVIDENGISHKVWHAGQKLKGVPWDVPIVG
CCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEE
YGAKTVNILRLWESRADEAFDWDVFNAGGYVDAQVEKSKAETISKVLYPNDSTDEGKELR
CCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIQQYFFCACSVKDILRRFRRAGNKWPILAEKVAIQLNDTHPTIAIPELMRILVDEERLD
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHCC
WNFAWSLCEKIFSYTNHTLLPEALEKWSVALFEKVLPRHLEIIYEINRRFLETVEQKWPG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNDIKAKLSIVEEGSQRMVRMANLCVVTSHKVNGVAAVHSELVKTDLFPEFDQLYPTKLI
CCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHCCHHHH
NVTNGITPRRWLKACNPALAALYDETVGKDWVVNLDKLKDALPKATDTVFQKRFMEIKRD
HHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHCC
NKVELVNIIKDLTGIEVSADAIFDIQIKRLHEYKRQQLNLIHILTLYRRLLDNPDYDMVP
CCHHHHHHHHHHCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RVFLFGAKAAPGYHMAKQIIYALNKVAEKVNSDKRIKGKLKVVFLPNYRVSLAEKMFPAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEEECCCHHHHHHHHCCCC
DISEQISTAGLEASGTGNMKFALNGALTVGTMDGANIEMAEEIGAEHMFIFGLSVAEVKE
CHHHHHHHCCCCCCCCCCEEEEEECEEEEEECCCCCCHHHHHCCCCEEEEEECCHHHHHH
LKTAGYNPYDYYYNNPELKAVLDWLDTDFFTPGQPGALSDIKRSLLEYGDEYLCLADYES
HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHH
YCKAHDAIDTTYRNKALWAEKAIRNSAAMGKFNSDRSIEDYVENVWHLKKYPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKKQAAKKTIIKNKSAEIVPAVACTTKQMRQAILDRLHKSLATEESKANNKAWWNATCY
CCHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
AVNELLFEKLTDTQKSHSGHDTRAVNYLSLEFLMGRLLSNNLHNLELFNVAQDALKGLGK
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCH
DLYEICEEEPDMALGNGGLGRLAACFIDSLATLGYPAIGYGIHYENGLFAQSFQDGRQIE
HHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHCCCCHHCCCEEECCCCCHHHHHCCCCCC
RPDTWREYGNPWEICRPESIQHVPLYGYVETVIDENGISHKVWHAGQKLKGVPWDVPIVG
CCCHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCEEE
YGAKTVNILRLWESRADEAFDWDVFNAGGYVDAQVEKSKAETISKVLYPNDSTDEGKELR
CCCHHHHHHHHHHHCCCCCCCCCEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LIQQYFFCACSVKDILRRFRRAGNKWPILAEKVAIQLNDTHPTIAIPELMRILVDEERLD
HHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEHHHHHHHHHHHHHCC
WNFAWSLCEKIFSYTNHTLLPEALEKWSVALFEKVLPRHLEIIYEINRRFLETVEQKWPG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DNDIKAKLSIVEEGSQRMVRMANLCVVTSHKVNGVAAVHSELVKTDLFPEFDQLYPTKLI
CCCCEEHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHCCCCHHHHCCHHHH
NVTNGITPRRWLKACNPALAALYDETVGKDWVVNLDKLKDALPKATDTVFQKRFMEIKRD
HHCCCCCHHHHHHHCCHHHHHHHHHHCCCCCEEEHHHHHHHCCHHHHHHHHHHHHHHHCC
NKVELVNIIKDLTGIEVSADAIFDIQIKRLHEYKRQQLNLIHILTLYRRLLDNPDYDMVP
CCHHHHHHHHHHCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
RVFLFGAKAAPGYHMAKQIIYALNKVAEKVNSDKRIKGKLKVVFLPNYRVSLAEKMFPAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEEECCCHHHHHHHHCCCC
DISEQISTAGLEASGTGNMKFALNGALTVGTMDGANIEMAEEIGAEHMFIFGLSVAEVKE
CHHHHHHHCCCCCCCCCCEEEEEECEEEEEECCCCCCHHHHHCCCCEEEEEECCHHHHHH
LKTAGYNPYDYYYNNPELKAVLDWLDTDFFTPGQPGALSDIKRSLLEYGDEYLCLADYES
HHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECHHH
YCKAHDAIDTTYRNKALWAEKAIRNSAAMGKFNSDRSIEDYVENVWHLKKYPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3037809; 9278503; 3155826; 2845225; 6283313; 6339728; 6986282; 9009262; 10220320; 10469642 [H]