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The map label for this gene is rpiA

Identifier: 119944374

GI number: 119944374

Start: 783748

End: 784404

Strand: Reverse

Name: rpiA

Synonym: Ping_0601

Alternate gene names: 119944374

Gene position: 784404-783748 (Counterclockwise)

Preceding gene: 119944375

Following gene: 119944373

Centisome position: 17.2

GC content: 40.79

Gene sequence:

>657_bases
ATGACACAAGATGAAATGAAAAAAGCAGCCGCCTATGCAGCCTTGGAATATGTACAGCCAGATTCAATTGTTGGCGTCGG
CACTGGCTCAACAGTGACTCATTTTATTGATGCGCTGGCAACCATAAAGGATCTTATCAAAGGTGCGGTTTCAAGCTCCG
ATGAGTCAACTGCAAGGTTACAATCCTATGGTATCGATGTTTTTGATCTTAATGAGGTTTCTGAATTGAGCATTTATGTC
GATGGTGCGGATGAAATAAATCCCTATAACCACATGATCAAAGGTGGCGGTGCAGCCTTAACGCGTGAAAAGATAATTTC
AGCGGTTGCTGAAAAATTTATCTGTATTGTGGATAACACTAAAAATGTTGATATTCTGGGTGACTTTCCATTACCTATTG
AAGTGATTCCGATGGCGCGCAGTTATGTCGCACGTGAATTGGTTAAATTAGGTGGAGATCCTGTTTATCGTCAGGGTGTG
GTAACAGACAATGGCAATGTGATTTTAGATGTTCATAACTTAAAAATTGCTGAACCCCTTAAATTAGAGGCGCAAATCAA
TGCGATTGTTGGCGTAGTCACCAATGGTTTATTTGCAAACCGTGCGGCTGATGTTGTTTTAGTTGGTACACCAGAAGGTG
TTAAAACGCTAAAATAA

Upstream 100 bases:

>100_bases
AAATCGCCCTATTTGATCATTATCACATGGATAACTAAACAGGATTGAGTATAATCTCCGCAACTTTTATAGCGAATGAT
AAAAACAGGAAGCCCGGACT

Downstream 100 bases:

>100_bases
GAACATCTTTGAGTGTGAGTGAGTATGGAAAACGCTGCACACACTCACCTCAAAAATAAAACGTAATAACTAAGTCAAAA
CTTTTATTTGTGAATTTCAT

Product: ribose 5-phosphate isomerase

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDEMKKAAAYAALEYVQPDSIVGVGTGSTVTHFIDALATIKDLIKGAVSSSDESTARLQSYGIDVFDLNEVSELSIYV
DGADEINPYNHMIKGGGAALTREKIISAVAEKFICIVDNTKNVDILGDFPLPIEVIPMARSYVARELVKLGGDPVYRQGV
VTDNGNVILDVHNLKIAEPLKLEAQINAIVGVVTNGLFANRAADVVLVGTPEGVKTLK

Sequences:

>Translated_218_residues
MTQDEMKKAAAYAALEYVQPDSIVGVGTGSTVTHFIDALATIKDLIKGAVSSSDESTARLQSYGIDVFDLNEVSELSIYV
DGADEINPYNHMIKGGGAALTREKIISAVAEKFICIVDNTKNVDILGDFPLPIEVIPMARSYVARELVKLGGDPVYRQGV
VTDNGNVILDVHNLKIAEPLKLEAQINAIVGVVTNGLFANRAADVVLVGTPEGVKTLK
>Mature_217_residues
TQDEMKKAAAYAALEYVQPDSIVGVGTGSTVTHFIDALATIKDLIKGAVSSSDESTARLQSYGIDVFDLNEVSELSIYVD
GADEINPYNHMIKGGGAALTREKIISAVAEKFICIVDNTKNVDILGDFPLPIEVIPMARSYVARELVKLGGDPVYRQGVV
TDNGNVILDVHNLKIAEPLKLEAQINAIVGVVTNGLFANRAADVVLVGTPEGVKTLK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=229, Percent_Identity=36.2445414847162, Blast_Score=117, Evalue=7e-27,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=74.1935483870968, Blast_Score=328, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=36.4485981308411, Blast_Score=109, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=224, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281364072, Length=207, Percent_Identity=33.8164251207729, Blast_Score=94, Evalue=9e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_PSYIN (A1SSJ0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942054.1
- ProteinModelPortal:   A1SSJ0
- SMR:   A1SSJ0
- STRING:   A1SSJ0
- GeneID:   4624247
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_0601
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   VFDLNSV
- PhylomeDB:   A1SSJ0
- BioCyc:   PING357804:PING_0601-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23258; Mature: 23127

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAAYAALEYVQPDSIVGVGTGSTVTHFIDALATIKDLIKGAVSSSDESTARL
CCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QSYGIDVFDLNEVSELSIYVDGADEINPYNHMIKGGGAALTREKIISAVAEKFICIVDNT
HHHCCCEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECC
KNVDILGDFPLPIEVIPMARSYVARELVKLGGDPVYRQGVVTDNGNVILDVHNLKIAEPL
CCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCHHCCCEEECCCCEEEEECCCEECCCE
KLEAQINAIVGVVTNGLFANRAADVVLVGTPEGVKTLK
EEHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure 
TQDEMKKAAAYAALEYVQPDSIVGVGTGSTVTHFIDALATIKDLIKGAVSSSDESTARL
CHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QSYGIDVFDLNEVSELSIYVDGADEINPYNHMIKGGGAALTREKIISAVAEKFICIVDNT
HHHCCCEEECCCCEEEEEEECCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHEEEEEECC
KNVDILGDFPLPIEVIPMARSYVARELVKLGGDPVYRQGVVTDNGNVILDVHNLKIAEPL
CCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCHHCCCEEECCCCEEEEECCCEECCCE
KLEAQINAIVGVVTNGLFANRAADVVLVGTPEGVKTLK
EEHHHHHHHHHHHHCCHHCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA