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The map label for this gene is ygfA [H]

Identifier: 119944375

GI number: 119944375

Start: 784935

End: 785525

Strand: Reverse

Name: ygfA [H]

Synonym: Ping_0602

Alternate gene names: 119944375

Gene position: 785525-784935 (Counterclockwise)

Preceding gene: 119944376

Following gene: 119944374

Centisome position: 17.23

GC content: 41.62

Gene sequence:

>591_bases
ATGAACAAAACACTTTCTCGAACAGAAATACGGCATCAAATCCGCACAGCAAGACGTGATCTTTCCGGCTTACAGCAAAA
ACAAGATGCAGACAGCTTATTCTCCCGTTTAATTAAACATTCGCGGGTTCAACAAGCGGGAAAAATATCGGTCACTCTTG
CTTATGATGGTGAAATAGATACGCTTCGATTTGTTGAGTGGTGCTGGCAAAAAAACAAAAAAATATACTTACCCGTTATA
CACCCCTTTAACAAAGGTCACTTGTTGTTTCTGGAGTACACCACAAAAACTGAAATGGTGCTTAATCAACACGGGATATT
TGAGCCCAAATTAAATCAATTAGATGCCTGCCCAATGAAAGAGTTAGATCTTATTTTCACTCCTCTGGTCGCATTTGATA
CACAGGGAAATAGGATTGGCATGGGAGGGGGGTATTACGACAGAATGCTGGCTCCCTGGTTTAAAGATAAAACCGGCCCC
TATCCAATAGGGTTAGCCCATGATTGCCAGCAAGTGCAGCAACTACCCGTTGAAGAATGGGATGTGCCTTTACCTGAAAT
AATAACTCCTTCAATGCACTTTTGTTGGTAA

Upstream 100 bases:

>100_bases
GGATAGCGTTAATAAAAAACGACCTGTCTGAGCCACTGTCAAAAATGTATTATGCGTAGTATTATTTCTCCACTCTACCG
CCATGGATTAGCATTGACCT

Downstream 100 bases:

>100_bases
GAACAAAACCCTAGAAAATGAATAAACAGCTAGCTACTTTAAGATCGAGAAATCAGCAAGTAGCTTGGGTACTGCTCTCC
CATAACGAACTTTCCGCTTT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MNKTLSRTEIRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCWQKNKKIYLPVI
HPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQLDACPMKELDLIFTPLVAFDTQGNRIGMGGGYYDRMLAPWFKDKTGP
YPIGLAHDCQQVQQLPVEEWDVPLPEIITPSMHFCW

Sequences:

>Translated_196_residues
MNKTLSRTEIRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCWQKNKKIYLPVI
HPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQLDACPMKELDLIFTPLVAFDTQGNRIGMGGGYYDRMLAPWFKDKTGP
YPIGLAHDCQQVQQLPVEEWDVPLPEIITPSMHFCW
>Mature_196_residues
MNKTLSRTEIRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEIDTLRFVEWCWQKNKKIYLPVI
HPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQLDACPMKELDLIFTPLVAFDTQGNRIGMGGGYYDRMLAPWFKDKTGP
YPIGLAHDCQQVQQLPVEEWDVPLPEIITPSMHFCW

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=189, Percent_Identity=28.042328042328, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI1789278, Length=183, Percent_Identity=48.0874316939891, Blast_Score=187, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17510857, Length=191, Percent_Identity=28.2722513089005, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22773; Mature: 22773

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTLSRTEIRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEID
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
TLRFVEWCWQKNKKIYLPVIHPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQLDACPMK
HHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCH
ELDLIFTPLVAFDTQGNRIGMGGGYYDRMLAPWFKDKTGPYPIGLAHDCQQVQQLPVEEW
HHHHHHHHHHEECCCCCEEECCCCHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHCCHHHC
DVPLPEIITPSMHFCW
CCCCHHHCCCCCCCCC
>Mature Secondary Structure
MNKTLSRTEIRHQIRTARRDLSGLQQKQDADSLFSRLIKHSRVQQAGKISVTLAYDGEID
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
TLRFVEWCWQKNKKIYLPVIHPFNKGHLLFLEYTTKTEMVLNQHGIFEPKLNQLDACPMK
HHHHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCCCCCH
ELDLIFTPLVAFDTQGNRIGMGGGYYDRMLAPWFKDKTGPYPIGLAHDCQQVQQLPVEEW
HHHHHHHHHHEECCCCCEEECCCCHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHCCHHHC
DVPLPEIITPSMHFCW
CCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]