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The map label for this gene is hoxJ [H]

Identifier: 119900099

GI number: 119900099

Start: 4170469

End: 4171854

Strand: Direct

Name: hoxJ [H]

Synonym: azo3810

Alternate gene names: 119900099

Gene position: 4170469-4171854 (Clockwise)

Preceding gene: 119900098

Following gene: 119900101

Centisome position: 95.3

GC content: 68.83

Gene sequence:

>1386_bases
ATGCCCGACCAGCCCCGCCATCCCGATCCGCTGCCGCCGCTGCAACACACCGGCCATCCCGGCGAACTCGTCGGCGTCGG
CGAGGACGTGTGGATGGACGTCATCCACAAGATGGACGAGGTCTATTCCGACCTGCTGCAGTACGAAGTGGCGCTGGAGG
AAAAGAACGCCAAGCTGGAGGAATCGCAGCAGTTCATCCTGTCGGTGCTGACCTCGATCTCCGACATCCTGGTGGTGTGT
GACCGCCACGGTGCCATCGAGGAGGTCAACCGCTCGCTGGAGGACTTCACCGGGCGCGACCTCGACAGCCTGCGCGGCAC
CTCGGTGTTCGAGCTGCTGGCCGACGACCAGGCCCGCGCCCAGCTGCGGCACCTGTTCTCGCTGTTCGGCGACCAGGCCC
TGCACGACTGCGAACTGCCGCTGCGCGCGCGCGACGGCAGTGCAGTGCCGGTGTCGCTCAACTGCACGCCGCGCTTCAAC
GCGGTCGGCAAGGCGATGGGGATGGTGGTCACCGGCCGCCCGGTGGGCGAACTCAAGCGCGCCTATCAGGCGCTGCGCCA
GGCCCACGAAGACCTCAAGCGCACCCAGCAGCAGCTGCTGCATTCCGAGAAGATGGCCTCGCTCGGGCGCCTGGTGGCCG
GCGTCGCCCACGAGCTGAACAACCCGATCAGCTTCATCCTCGGCAACGTCCACGCGCTCAAGCGCTACGCCGGCCGGCTG
GAGAGCTACCTCGGCGCGATCCACGGCGGCGACAGCGCGGAACACCTCGCCCAGCTGCGCACGCGGCTGCGCATAGACCG
CCTGCTCGGCGACCTGCCGGCGCTGATCGACGGCACCATCGAGGGCGCCGAACGCACGCGCGACATCGTGGACGGCCTCA
AGCGCTTCTCCGCGATCGACCGCGAGGTGAACGAAGCCTTCGACCTCGCCGAGGTGATCGAGCGCGCGGTGAGTTGGGTG
CGGCGCGGCGCGCGCGACAGCTTCCACGTGCGCTTCTCGATGCCGCGCAAGATCCCGATGACCGGCTCGGCCGGGCAGAT
GCAGCAGGTGATGATGAATCTGGTGCAGAACGCCTGGGACGCCACCGCGGAACAGCCCGAACAGTGGCTGGACATCCTCG
CGGAGGTGGAGGCGGGCACGGATACCGGCGGCGCGCGCGTGCGGGTGAGCTTTCACGACAACGGGCCGGGCATCGCGGCC
CAGCATCTGCCGCAGGTGTTCGACCCCTTCTTTTCGACCAAGCAGGTGGGCAAGGGCACCGGGCTGGGGCTGTCGATCAG
CTACGGCATCATCGAGCGCCACGGCGGGCGCATCAGCGCCGCCAACCATCCGGCCGGCGGCGCCATCTTCACGGTCGAGC
TGCCGCTGGCAGGCGTGGGGGCGTAA

Upstream 100 bases:

>100_bases
CTCTACCGGGCCAAGGAAAGCGGCCGCGACCGCCTCGAATGGACGCCGGCCGACTCAGGCGTGTGCTAGCGTGAAGCCAG
CCTGACCGCCGCTCGCCATC

Downstream 100 bases:

>100_bases
GCCGCTTCAGGCGAGGCGGCGGTAAGCGCCGCCGTGGTAGATCAGCGGCGGCAGCTCGTTGCGGTCGAAATCCACGACTT
CGCTGATGAACACCACGTGG

Product: hydrogen uptake histidine-kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MPDQPRHPDPLPPLQHTGHPGELVGVGEDVWMDVIHKMDEVYSDLLQYEVALEEKNAKLEESQQFILSVLTSISDILVVC
DRHGAIEEVNRSLEDFTGRDLDSLRGTSVFELLADDQARAQLRHLFSLFGDQALHDCELPLRARDGSAVPVSLNCTPRFN
AVGKAMGMVVTGRPVGELKRAYQALRQAHEDLKRTQQQLLHSEKMASLGRLVAGVAHELNNPISFILGNVHALKRYAGRL
ESYLGAIHGGDSAEHLAQLRTRLRIDRLLGDLPALIDGTIEGAERTRDIVDGLKRFSAIDREVNEAFDLAEVIERAVSWV
RRGARDSFHVRFSMPRKIPMTGSAGQMQQVMMNLVQNAWDATAEQPEQWLDILAEVEAGTDTGGARVRVSFHDNGPGIAA
QHLPQVFDPFFSTKQVGKGTGLGLSISYGIIERHGGRISAANHPAGGAIFTVELPLAGVGA

Sequences:

>Translated_461_residues
MPDQPRHPDPLPPLQHTGHPGELVGVGEDVWMDVIHKMDEVYSDLLQYEVALEEKNAKLEESQQFILSVLTSISDILVVC
DRHGAIEEVNRSLEDFTGRDLDSLRGTSVFELLADDQARAQLRHLFSLFGDQALHDCELPLRARDGSAVPVSLNCTPRFN
AVGKAMGMVVTGRPVGELKRAYQALRQAHEDLKRTQQQLLHSEKMASLGRLVAGVAHELNNPISFILGNVHALKRYAGRL
ESYLGAIHGGDSAEHLAQLRTRLRIDRLLGDLPALIDGTIEGAERTRDIVDGLKRFSAIDREVNEAFDLAEVIERAVSWV
RRGARDSFHVRFSMPRKIPMTGSAGQMQQVMMNLVQNAWDATAEQPEQWLDILAEVEAGTDTGGARVRVSFHDNGPGIAA
QHLPQVFDPFFSTKQVGKGTGLGLSISYGIIERHGGRISAANHPAGGAIFTVELPLAGVGA
>Mature_460_residues
PDQPRHPDPLPPLQHTGHPGELVGVGEDVWMDVIHKMDEVYSDLLQYEVALEEKNAKLEESQQFILSVLTSISDILVVCD
RHGAIEEVNRSLEDFTGRDLDSLRGTSVFELLADDQARAQLRHLFSLFGDQALHDCELPLRARDGSAVPVSLNCTPRFNA
VGKAMGMVVTGRPVGELKRAYQALRQAHEDLKRTQQQLLHSEKMASLGRLVAGVAHELNNPISFILGNVHALKRYAGRLE
SYLGAIHGGDSAEHLAQLRTRLRIDRLLGDLPALIDGTIEGAERTRDIVDGLKRFSAIDREVNEAFDLAEVIERAVSWVR
RGARDSFHVRFSMPRKIPMTGSAGQMQQVMMNLVQNAWDATAEQPEQWLDILAEVEAGTDTGGARVRVSFHDNGPGIAAQ
HLPQVFDPFFSTKQVGKGTGLGLSISYGIIERHGGRISAANHPAGGAIFTVELPLAGVGA

Specific function: Member of the two-component regulatory system nodV/nodW probably involved in the regulation of the transcription of genes involved in the nodulation process. NodV may function as a membrane-associated protein kinase that phosphorylates nodW in response to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=30.188679245283, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788549, Length=404, Percent_Identity=24.7524752475248, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790300, Length=399, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=296, Percent_Identity=26.0135135135135, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=263, Percent_Identity=27.3764258555133, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI145693157, Length=128, Percent_Identity=37.5, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50543; Mature: 50412

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDQPRHPDPLPPLQHTGHPGELVGVGEDVWMDVIHKMDEVYSDLLQYEVALEEKNAKLE
CCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ESQQFILSVLTSISDILVVCDRHGAIEEVNRSLEDFTGRDLDSLRGTSVFELLADDQARA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCHHHHH
QLRHLFSLFGDQALHDCELPLRARDGSAVPVSLNCTPRFNAVGKAMGMVVTGRPVGELKR
HHHHHHHHHCCHHHHHCCCCCEECCCCEEEEEEECCCCHHHHHHHHCEEECCCCHHHHHH
AYQALRQAHEDLKRTQQQLLHSEKMASLGRLVAGVAHELNNPISFILGNVHALKRYAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ESYLGAIHGGDSAEHLAQLRTRLRIDRLLGDLPALIDGTIEGAERTRDIVDGLKRFSAID
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
REVNEAFDLAEVIERAVSWVRRGARDSFHVRFSMPRKIPMTGSAGQMQQVMMNLVQNAWD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHC
ATAEQPEQWLDILAEVEAGTDTGGARVRVSFHDNGPGIAAQHLPQVFDPFFSTKQVGKGT
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLGLSISYGIIERHGGRISAANHPAGGAIFTVELPLAGVGA
CCCEEEEHHHHHHCCCEEECCCCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
PDQPRHPDPLPPLQHTGHPGELVGVGEDVWMDVIHKMDEVYSDLLQYEVALEEKNAKLE
CCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
ESQQFILSVLTSISDILVVCDRHGAIEEVNRSLEDFTGRDLDSLRGTSVFELLADDQARA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHCHHHHH
QLRHLFSLFGDQALHDCELPLRARDGSAVPVSLNCTPRFNAVGKAMGMVVTGRPVGELKR
HHHHHHHHHCCHHHHHCCCCCEECCCCEEEEEEECCCCHHHHHHHHCEEECCCCHHHHHH
AYQALRQAHEDLKRTQQQLLHSEKMASLGRLVAGVAHELNNPISFILGNVHALKRYAGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ESYLGAIHGGDSAEHLAQLRTRLRIDRLLGDLPALIDGTIEGAERTRDIVDGLKRFSAID
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
REVNEAFDLAEVIERAVSWVRRGARDSFHVRFSMPRKIPMTGSAGQMQQVMMNLVQNAWD
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHC
ATAEQPEQWLDILAEVEAGTDTGGARVRVSFHDNGPGIAAQHLPQVFDPFFSTKQVGKGT
CCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GLGLSISYGIIERHGGRISAANHPAGGAIFTVELPLAGVGA
CCCEEEEHHHHHHCCCEEECCCCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2320582; 11157954; 12597275 [H]