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The map label for this gene is adrA [H]

Identifier: 119900098

GI number: 119900098

Start: 4168926

End: 4170437

Strand: Direct

Name: adrA [H]

Synonym: azo3809

Alternate gene names: 119900098

Gene position: 4168926-4170437 (Clockwise)

Preceding gene: 119900097

Following gene: 119900099

Centisome position: 95.27

GC content: 69.91

Gene sequence:

>1512_bases
TTGAGCGCCGCACGCTGGGCGATCGCCGGGGCCATCGTGCTGCTGGTGACGGACCTGCTGCTGGCGTGGGTGCTGTGGAA
CGAACGCGAACGCGCGCTGGAGCGCGGTCAGGAGTCGGTCACGCTGGCGGCCGCAACCGCCCTGCGGCGCGCCGAGAGCC
TGTTCGAACTGCTCGACCGCACCCTGTCCGGCGTCAGCGAGGTGGTGGCGGCGCGCGCCAGCACCGCGCCGGACGACCTT
TACCTGCACCGCCTGCTGCTCCGGCGCAACGCGATCACGCCGGCCCTCGTCTCGATCAACCTCATCGGCGCCGACGGCCG
CCTCCTCAGCACCTCGCGCACCTATCCGGCGCCGCCGATCGACCTCTCCGACCGGGACTACGTGAAGGCGCAGATCGATG
ACTGGAACAAGGGCCTGTTCCTCGGCAGCCCGGTCACTTCGCGCCTGAGCGGCATCCAGATCGTGCCGATCAGCCGGCGC
ATCAACAACGACGGCGGCCGCCTGATCGGTGTCGTCTCGGGGGCGATCGATCCCCACTACCTTCACGATCTGGTGTCCAA
CGGCGCCGACGGCCTGCTGCTTGGCATCTTCCGCCGCGACGGCCATGCGCTGGCCTGCCTGCCGCACCGCGAGGAATGCC
CCGATGCGCCGCCGCAGGTAAAGCACATGATCGACAGCGACCTGGAAGGCGGCGCCGAGGCCGAGATCAGCAAAGTGCGC
CTGCTCGGCAAGGGCCGCGGCATTTCGGTCTATCTGCCCTCGCGCGACGGCCAGTTCTTCGTCGTTGCCGACCTGCCGAG
CAAGACCCTGCTCGCCTCCTGGCATGCGAACCTGCCGGTGTTCCTGGTGATCGCGCTCGGCGGCAACGTCGCGCTGATGG
TGATCGGGCTCTACGCCTACCGTCAGGTCACCCGCCGCCGCCAGGCACTGGACGAATTGGCCGCCACCAACCGCGAACTG
GAAGACCGGGTGCGCGAACGCACCCGCGAGCTGCACCGGCTGGCCCACACCGACGTGCTGACCGGCGCACGCAACCGGCG
CGCCTTCATGGACGAAGGCGAGGCGCTGTTCGCGCTCGCGCACCGCCACCATCGCGACCTCGCGGTGATGGTGCTCGACG
TGGACCGCTTCAAGTCGATCAACGACCGCTACGGCCACGCCGGTGGCGACGCGGTGCTGCGCGCGCTCGCCACCGTGCCC
GACAGCGTGCTGCGCACCTCCGACCTGTTCGCCCGCTTCGGCGGCGAGGAGTTCGCCATCGTGCTGCCGGAAACCGACTG
CATGGGTGCGATGGAAGTCGGCCAGCGCCTGCTCGCGGCCTTCCGCGAATGCGAGGTGCCACACGACGGCCAGGTGCTGC
GCTTCACGGTGTCGATCGGGCTGAGCGTGATCGGACCCGCCGACGCCAGCCTGGAAGCGCTGCTGCAGCGTGCCGACCTG
GCCCTCTACCGGGCCAAGGAAAGCGGCCGCGACCGCCTCGAATGGACGCCGGCCGACTCAGGCGTGTGCTAG

Upstream 100 bases:

>100_bases
CGGTGCCGTGCCGCATGCCCTTGGCCGCAGGAGCGGCAAGTGGATACCCTGTACCCGGACAGGTCGTGAAGGAGAGTGCG
TGAGGGCATCGGACTGGGGC

Downstream 100 bases:

>100_bases
CGTGAAGCCAGCCTGACCGCCGCTCGCCATCATGCCCGACCAGCCCCGCCATCCCGATCCGCTGCCGCCGCTGCAACACA
CCGGCCATCCCGGCGAACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSAARWAIAGAIVLLVTDLLLAWVLWNERERALERGQESVTLAAATALRRAESLFELLDRTLSGVSEVVAARASTAPDDL
YLHRLLLRRNAITPALVSINLIGADGRLLSTSRTYPAPPIDLSDRDYVKAQIDDWNKGLFLGSPVTSRLSGIQIVPISRR
INNDGGRLIGVVSGAIDPHYLHDLVSNGADGLLLGIFRRDGHALACLPHREECPDAPPQVKHMIDSDLEGGAEAEISKVR
LLGKGRGISVYLPSRDGQFFVVADLPSKTLLASWHANLPVFLVIALGGNVALMVIGLYAYRQVTRRRQALDELAATNREL
EDRVRERTRELHRLAHTDVLTGARNRRAFMDEGEALFALAHRHHRDLAVMVLDVDRFKSINDRYGHAGGDAVLRALATVP
DSVLRTSDLFARFGGEEFAIVLPETDCMGAMEVGQRLLAAFRECEVPHDGQVLRFTVSIGLSVIGPADASLEALLQRADL
ALYRAKESGRDRLEWTPADSGVC

Sequences:

>Translated_503_residues
MSAARWAIAGAIVLLVTDLLLAWVLWNERERALERGQESVTLAAATALRRAESLFELLDRTLSGVSEVVAARASTAPDDL
YLHRLLLRRNAITPALVSINLIGADGRLLSTSRTYPAPPIDLSDRDYVKAQIDDWNKGLFLGSPVTSRLSGIQIVPISRR
INNDGGRLIGVVSGAIDPHYLHDLVSNGADGLLLGIFRRDGHALACLPHREECPDAPPQVKHMIDSDLEGGAEAEISKVR
LLGKGRGISVYLPSRDGQFFVVADLPSKTLLASWHANLPVFLVIALGGNVALMVIGLYAYRQVTRRRQALDELAATNREL
EDRVRERTRELHRLAHTDVLTGARNRRAFMDEGEALFALAHRHHRDLAVMVLDVDRFKSINDRYGHAGGDAVLRALATVP
DSVLRTSDLFARFGGEEFAIVLPETDCMGAMEVGQRLLAAFRECEVPHDGQVLRFTVSIGLSVIGPADASLEALLQRADL
ALYRAKESGRDRLEWTPADSGVC
>Mature_502_residues
SAARWAIAGAIVLLVTDLLLAWVLWNERERALERGQESVTLAAATALRRAESLFELLDRTLSGVSEVVAARASTAPDDLY
LHRLLLRRNAITPALVSINLIGADGRLLSTSRTYPAPPIDLSDRDYVKAQIDDWNKGLFLGSPVTSRLSGIQIVPISRRI
NNDGGRLIGVVSGAIDPHYLHDLVSNGADGLLLGIFRRDGHALACLPHREECPDAPPQVKHMIDSDLEGGAEAEISKVRL
LGKGRGISVYLPSRDGQFFVVADLPSKTLLASWHANLPVFLVIALGGNVALMVIGLYAYRQVTRRRQALDELAATNRELE
DRVRERTRELHRLAHTDVLTGARNRRAFMDEGEALFALAHRHHRDLAVMVLDVDRFKSINDRYGHAGGDAVLRALATVPD
SVLRTSDLFARFGGEEFAIVLPETDCMGAMEVGQRLLAAFRECEVPHDGQVLRFTVSIGLSVIGPADASLEALLQRADLA
LYRAKESGRDRLEWTPADSGVC

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=172, Percent_Identity=35.4651162790698, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788381, Length=169, Percent_Identity=35.5029585798817, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=39.2857142857143, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=37.3417721518987, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI145693134, Length=163, Percent_Identity=35.5828220858896, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=37.3417721518987, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=32.5581395348837, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=34.5454545454545, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=33.7142857142857, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=32.5443786982249, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=168, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788956, Length=285, Percent_Identity=31.9298245614035, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787056, Length=177, Percent_Identity=31.0734463276836, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 55104; Mature: 54973

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAARWAIAGAIVLLVTDLLLAWVLWNERERALERGQESVTLAAATALRRAESLFELLDR
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TLSGVSEVVAARASTAPDDLYLHRLLLRRNAITPALVSINLIGADGRLLSTSRTYPAPPI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCC
DLSDRDYVKAQIDDWNKGLFLGSPVTSRLSGIQIVPISRRINNDGGRLIGVVSGAIDPHY
CCCCCCEEEEECCCCCCCEEECCCHHHHHCCEEEEEEHHHCCCCCCEEEEEEECCCCHHH
LHDLVSNGADGLLLGIFRRDGHALACLPHREECPDAPPQVKHMIDSDLEGGAEAEISKVR
HHHHHHCCCCEEEEEEEECCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCCCCHHHHHEE
LLGKGRGISVYLPSRDGQFFVVADLPSKTLLASWHANLPVFLVIALGGNVALMVIGLYAY
EEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
RQVTRRRQALDELAATNRELEDRVRERTRELHRLAHTDVLTGARNRRAFMDEGEALFALA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
HRHHRDLAVMVLDVDRFKSINDRYGHAGGDAVLRALATVPDSVLRTSDLFARFGGEEFAI
HHCCCCEEEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
VLPETDCMGAMEVGQRLLAAFRECEVPHDGQVLRFTVSIGLSVIGPADASLEALLQRADL
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEEEECCCCHHHHHHHHHHHH
ALYRAKESGRDRLEWTPADSGVC
HHHHHHHCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SAARWAIAGAIVLLVTDLLLAWVLWNERERALERGQESVTLAAATALRRAESLFELLDR
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
TLSGVSEVVAARASTAPDDLYLHRLLLRRNAITPALVSINLIGADGRLLSTSRTYPAPPI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEECCCCCCCCCC
DLSDRDYVKAQIDDWNKGLFLGSPVTSRLSGIQIVPISRRINNDGGRLIGVVSGAIDPHY
CCCCCCEEEEECCCCCCCEEECCCHHHHHCCEEEEEEHHHCCCCCCEEEEEEECCCCHHH
LHDLVSNGADGLLLGIFRRDGHALACLPHREECPDAPPQVKHMIDSDLEGGAEAEISKVR
HHHHHHCCCCEEEEEEEECCCCEEEECCCHHHCCCCCHHHHHHHHCCCCCCCCHHHHHEE
LLGKGRGISVYLPSRDGQFFVVADLPSKTLLASWHANLPVFLVIALGGNVALMVIGLYAY
EEECCCCEEEEEECCCCCEEEEEECCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHH
RQVTRRRQALDELAATNRELEDRVRERTRELHRLAHTDVLTGARNRRAFMDEGEALFALA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHH
HRHHRDLAVMVLDVDRFKSINDRYGHAGGDAVLRALATVPDSVLRTSDLFARFGGEEFAI
HHCCCCEEEEEEEHHHHHCCHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEE
VLPETDCMGAMEVGQRLLAAFRECEVPHDGQVLRFTVSIGLSVIGPADASLEALLQRADL
EECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECEEEECCCCHHHHHHHHHHHH
ALYRAKESGRDRLEWTPADSGVC
HHHHHHHCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]