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The map label for this gene is hypA

Identifier: 119900088

GI number: 119900088

Start: 4157987

End: 4158331

Strand: Direct

Name: hypA

Synonym: azo3799

Alternate gene names: 119900088

Gene position: 4157987-4158331 (Clockwise)

Preceding gene: 119900087

Following gene: 119900089

Centisome position: 95.02

GC content: 69.28

Gene sequence:

>345_bases
ATGCATGAGATGTCGCTCGCCGAGGGCATACGCGGCATCGTCGAAGACGTCGCGCGCGAGAACGGCGCGACACGGGTGGC
GCGGGTGGTGCTGGAAATCGGCGAACTCGCCTCGGTCGAGGTCGAGGCGCTGCGCTTCTGCCTGGACGTGGTGCTGAAGG
ACAGCGTCGCGGACGGCGCCGCCGTGGACATCGAGGCGGTGCCCGGCAGCGGCTGGTGCATGCAGTGCGCCACAGTGGTG
CCGATCGCCCAGCGCTACGATGCCTGTCCACAGTGCGGCGGCTATCAGGTGCAGCCGACGGGCGGCACCGAGATGCGGGT
GAAGGAACTGGCGCTGGGCGACTGA

Upstream 100 bases:

>100_bases
CACGCCGCCGACGAGGCCGGCACCCGGCTGCGGCTGCACGCACTCGCGCTGTCGCTCGACCCCTGCGTGGCCTTCGAGCT
GAGCGTGGAGGACAGCGTCC

Downstream 100 bases:

>100_bases
CTGAACGACACCCGCCCGAGGGATGGAACGGAAACGTAAGCAGGCGCCGGGACAGGCCTGATTTACTCCCTCCCCTTCAA
GGGGAGAAACGACAAAGCCG

Product: hydrogenase nickel inorporation protein hypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 114; Mature: 114

Protein sequence:

>114_residues
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGAAVDIEAVPGSGWCMQCATVV
PIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD

Sequences:

>Translated_114_residues
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGAAVDIEAVPGSGWCMQCATVV
PIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD
>Mature_114_residues
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGAAVDIEAVPGSGWCMQCATVV
PIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=110, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=9e-16,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=33.6283185840708, Blast_Score=74, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_AZOSB (A1KC59)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_935301.1
- STRING:   A1KC59
- GeneID:   4609050
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo3799
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- PhylomeDB:   A1KC59
- ProtClustDB:   CLSK2487522
- BioCyc:   ASP62928:AZO3799-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12064; Mature: 12064

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVDIEAVPGSGWCMQCATVVPIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MHEMSLAEGIRGIVEDVARENGATRVARVVLEIGELASVEVEALRFCLDVVLKDSVADGA
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AVDIEAVPGSGWCMQCATVVPIAQRYDACPQCGGYQVQPTGGTEMRVKELALGD
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA