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The map label for this gene is hypB [H]

Identifier: 119900089

GI number: 119900089

Start: 4158470

End: 4159393

Strand: Direct

Name: hypB [H]

Synonym: azo3800

Alternate gene names: 119900089

Gene position: 4158470-4159393 (Clockwise)

Preceding gene: 119900088

Following gene: 119900090

Centisome position: 95.03

GC content: 70.45

Gene sequence:

>924_bases
ATGTGCACGGTTTGCGGCTGCGGCAGTGGCGAATTGCGATACAACGGTCAGCCCGCGACGGCCAAGGCGGCGCGCAAACC
CGCGGTCGCGACCGGCTTTCGCCCGCTGCCGGCTTCGCCCGCGGTGGGTGAGCCGCCCGCGCATGCACATCACGACCCTG
CGCCGGTTGCCCGCGCCGGCGCGCTCGACTACGGCCAGGGCCCGGCCCATGCCCATGCGCCGGGGCTGTCGCAGCAGCAG
ATGGTGAAGATCGAGCGCGACATCCTCGGCAAGAACGACGCGCTCGCCGCCGCCAACCGCAACTGGCTCGCGCGGCGCGG
CGTGTTCGCACTCAACCTCGTCTCCAGCCCGGGCTCGGGCAAGACCACGCTGCTGGTGAAGACCATCGAACGCCTCGCCG
GCCGCGTGCCGGTGGCGGTGATCGAGGGCGACCAGCAGACCGAGTTCGACGCCGAGCGCATCCGCGCCACCGGCGCGCCG
GCGCTGCAGATCAACACCGGCAAGGGCTGTCACCTCGACGCCCACATGGTGGGCGAAGCCTTCTCGCGGCTGCCGATCGC
CGAGCGCAGCCTGCTGCTGATCGAGAACGTCGGCAACCTCGTCTGTCCGGCCGCGTTCGACCTCGGCGAGGCCCACAAGG
TGGTGATCCTGTCGGTGACCGAGGGCGAGGACAAGCCGCTGAAGTATCCGGACATGTTCGCCGCGGCCGACCTGATGCTG
CTCTCCAAGGTCGACCTGCTGCCCTACCTCAGTTTCGACGTCGCGCGCGCGATCGGCTATGCGCGCCGGGTCAATCCGCG
GCTGCAGGTGCTGCAGCTGTCGTCCACCAGCGGAAGCGGTTTCGACGAATGGCTGGCGTGGATCGACGCCGGCCTCGCAG
ACCGGGCCGGCGCCGCGGCCCGCGCAGCGGAGAACCCATCATGA

Upstream 100 bases:

>100_bases
AGCAGGCGCCGGGACAGGCCTGATTTACTCCCTCCCCTTCAAGGGGAGAAACGACAAAGCCGCCGCGGATGGTCGCGGCA
ACACATGGAGAACACACGAG

Downstream 100 bases:

>100_bases
GCGAAGACACCAGCACCAGTCCGCGGCAGCCGCGCTTCGAACGGCGGCGCTTCTACGTGCGCGGGGTGGTCCAGGGCGTG
GGTTTCCGGCCCTTCGTGTA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MCTVCGCGSGELRYNGQPATAKAARKPAVATGFRPLPASPAVGEPPAHAHHDPAPVARAGALDYGQGPAHAHAPGLSQQQ
MVKIERDILGKNDALAAANRNWLARRGVFALNLVSSPGSGKTTLLVKTIERLAGRVPVAVIEGDQQTEFDAERIRATGAP
ALQINTGKGCHLDAHMVGEAFSRLPIAERSLLLIENVGNLVCPAAFDLGEAHKVVILSVTEGEDKPLKYPDMFAAADLML
LSKVDLLPYLSFDVARAIGYARRVNPRLQVLQLSSTSGSGFDEWLAWIDAGLADRAGAAARAAENPS

Sequences:

>Translated_307_residues
MCTVCGCGSGELRYNGQPATAKAARKPAVATGFRPLPASPAVGEPPAHAHHDPAPVARAGALDYGQGPAHAHAPGLSQQQ
MVKIERDILGKNDALAAANRNWLARRGVFALNLVSSPGSGKTTLLVKTIERLAGRVPVAVIEGDQQTEFDAERIRATGAP
ALQINTGKGCHLDAHMVGEAFSRLPIAERSLLLIENVGNLVCPAAFDLGEAHKVVILSVTEGEDKPLKYPDMFAAADLML
LSKVDLLPYLSFDVARAIGYARRVNPRLQVLQLSSTSGSGFDEWLAWIDAGLADRAGAAARAAENPS
>Mature_307_residues
MCTVCGCGSGELRYNGQPATAKAARKPAVATGFRPLPASPAVGEPPAHAHHDPAPVARAGALDYGQGPAHAHAPGLSQQQ
MVKIERDILGKNDALAAANRNWLARRGVFALNLVSSPGSGKTTLLVKTIERLAGRVPVAVIEGDQQTEFDAERIRATGAP
ALQINTGKGCHLDAHMVGEAFSRLPIAERSLLLIENVGNLVCPAAFDLGEAHKVVILSVTEGEDKPLKYPDMFAAADLML
LSKVDLLPYLSFDVARAIGYARRVNPRLQVLQLSSTSGSGFDEWLAWIDAGLADRAGAAARAAENPS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=295, Percent_Identity=56.6101694915254, Blast_Score=330, Evalue=7e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 32330; Mature: 32330

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTVCGCGSGELRYNGQPATAKAARKPAVATGFRPLPASPAVGEPPAHAHHDPAPVARAG
CCEEECCCCCCEEECCCCCHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
ALDYGQGPAHAHAPGLSQQQMVKIERDILGKNDALAAANRNWLARRGVFALNLVSSPGSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCHHHHCCEEEEEEECCCCCC
KTTLLVKTIERLAGRVPVAVIEGDQQTEFDAERIRATGAPALQINTGKGCHLDAHMVGEA
CEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEECCCCCEEHHHHHHHH
FSRLPIAERSLLLIENVGNLVCPAAFDLGEAHKVVILSVTEGEDKPLKYPDMFAAADLML
HHHCCCCCCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LSKVDLLPYLSFDVARAIGYARRVNPRLQVLQLSSTSGSGFDEWLAWIDAGLADRAGAAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHCCHHH
RAAENPS
HCCCCCC
>Mature Secondary Structure
MCTVCGCGSGELRYNGQPATAKAARKPAVATGFRPLPASPAVGEPPAHAHHDPAPVARAG
CCEEECCCCCCEEECCCCCHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHC
ALDYGQGPAHAHAPGLSQQQMVKIERDILGKNDALAAANRNWLARRGVFALNLVSSPGSG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCHHHHCCEEEEEEECCCCCC
KTTLLVKTIERLAGRVPVAVIEGDQQTEFDAERIRATGAPALQINTGKGCHLDAHMVGEA
CEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHCCCCEEEEECCCCCEEHHHHHHHH
FSRLPIAERSLLLIENVGNLVCPAAFDLGEAHKVVILSVTEGEDKPLKYPDMFAAADLML
HHHCCCCCCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHH
LSKVDLLPYLSFDVARAIGYARRVNPRLQVLQLSSTSGSGFDEWLAWIDAGLADRAGAAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCHHHCCHHH
RAAENPS
HCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]