Click here to switch to the map view.

The map label for this gene is qseC2 [H]

Identifier: 119899962

GI number: 119899962

Start: 4032106

End: 4033452

Strand: Direct

Name: qseC2 [H]

Synonym: azo3673

Alternate gene names: 119899962

Gene position: 4032106-4033452 (Clockwise)

Preceding gene: 119899961

Following gene: 119899963

Centisome position: 92.14

GC content: 72.61

Gene sequence:

>1347_bases
TTGCGGCGCCAGTTGCTGATCACGCTGCTCGGCGCGGTGCTCGGCGTATTCCTGATCGGCAGCCTCGCCACCTACCAGAC
CACGCGCGGCGAGGTGGACGAGATCATGGACTACCACCTGCGCCAGCTCGCGCTCTCGCTGCGGGCGCCGCAATACGGCG
CCCAACCGGAGCTCGGCCCCGACGACCAGCTCTTCGACATGGTCATCCAGGTGTGGGACGAACAGGGGCTGCGCCTCTAT
CTGTCGCGCCCCCACACCGCGCTGCCCGACCGCGCGCAGCTCGGCTACGCCACGGTACCGACGGCCGAAGGCGACTGGCG
CACCTATTCCATCGTGATGGGCAGCCGTGTGGTCCAGGTGGCGCAGCCGATGTCTCACCGTAACCGTCTCGCCGCCGCGG
CGGCGCTGCGCACGCTGACGCCGCTGCTGGTGATCCTTCCGCTGCTGGCCGGCTTGATCTGGTATCTCGTGGGGCGCGGC
CTGCGCCCGCTGGAGCGGCTGGCGCGCGCGGTGGGCCAACGCCGGCCGGACAGCCTTGCACCGCTCGCGGTCGCTGGCGT
GCCGGACGAGGCCCAGCCGCTGGTGCAGGCGCTGAACGGACTGCTCGGCCGGCTCGACCACGCGATGAGCGCGCAGCGTG
CCTTCGTCGCCGACGCCGCGCACGAGCTGCGCACGCCGCTGGCGGCGCTCCAGCTGCAACTGCAACTGACCGAACGCGCC
GGGTCCGAAGCGGAGCGCCGCGCCGCCCTCGGCGAACTGCGCCAGGGGCTGCTGCGCGCCACCCGCGTGGTCCAGCAACT
GCTCACGCTGGCGCGCCAGACGCCGGACGCCGCCGCGGCGGGTGCGCCCCCGGCCGTCGTGGACCTGGTCGAACTGGTTG
CACTGGTCACCGCCGAACTGCAAGCGCTGGCCGAAGCGCGCGGCATTGACCTGGGCGCCGAGCAGTTGGACAGCGGCAGC
ACCGTCCACGGTGACCGCGACAGCCTGCGCACGCTGGTGGTCAACCTGATCGACAACGCGATCCGCTACACCCCCGCCGG
GGGCCGGGTGGACCTGCGGGTATGGCACGAGAACGGCCGCGTGTGGCTGGAGGTCGCGGACGACGGGCCCGGCATCCCGG
TCGAGGAACGCGAGCGGGTGCTCGACCGCTTCTACCGCCGCGCCGGGCAGGAGCAACCCGGCAGCGGCCTCGGACTGGCG
ATCGTGAAGGCGATTGCCGACCGGCACGGCGCCGAACTGCGGCTCGACGAATCGGCGCGCGGCGGACTGGCGGTCCGCGT
CGGCCTGCCGGCCGCGCCGGTCGCGGCGGAAGAGACATCCGGTAACACGGCAGGGGTAGAACCTTAA

Upstream 100 bases:

>100_bases
CCGGCCGCACCCGGATGACGCGGGCACGCCCCCCGCCCGGCCGGCCCGCCGCGGCCTCGCGCGGCGCGCCGGCCCGCGCC
ACCGGCCCGGCTGGCTGTCC

Downstream 100 bases:

>100_bases
GTCTGCTTTAAGTCGGCCTCCCTTAAGGTGCCGGGCAAGCGGAACAACCGCATACCGAGCCTTCCAGGAGACCGAGCATG
CAACACCCCCTGCGCGCCAC

Product: two-component system histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MRRQLLITLLGAVLGVFLIGSLATYQTTRGEVDEIMDYHLRQLALSLRAPQYGAQPELGPDDQLFDMVIQVWDEQGLRLY
LSRPHTALPDRAQLGYATVPTAEGDWRTYSIVMGSRVVQVAQPMSHRNRLAAAAALRTLTPLLVILPLLAGLIWYLVGRG
LRPLERLARAVGQRRPDSLAPLAVAGVPDEAQPLVQALNGLLGRLDHAMSAQRAFVADAAHELRTPLAALQLQLQLTERA
GSEAERRAALGELRQGLLRATRVVQQLLTLARQTPDAAAAGAPPAVVDLVELVALVTAELQALAEARGIDLGAEQLDSGS
TVHGDRDSLRTLVVNLIDNAIRYTPAGGRVDLRVWHENGRVWLEVADDGPGIPVEERERVLDRFYRRAGQEQPGSGLGLA
IVKAIADRHGAELRLDESARGGLAVRVGLPAAPVAAEETSGNTAGVEP

Sequences:

>Translated_448_residues
MRRQLLITLLGAVLGVFLIGSLATYQTTRGEVDEIMDYHLRQLALSLRAPQYGAQPELGPDDQLFDMVIQVWDEQGLRLY
LSRPHTALPDRAQLGYATVPTAEGDWRTYSIVMGSRVVQVAQPMSHRNRLAAAAALRTLTPLLVILPLLAGLIWYLVGRG
LRPLERLARAVGQRRPDSLAPLAVAGVPDEAQPLVQALNGLLGRLDHAMSAQRAFVADAAHELRTPLAALQLQLQLTERA
GSEAERRAALGELRQGLLRATRVVQQLLTLARQTPDAAAAGAPPAVVDLVELVALVTAELQALAEARGIDLGAEQLDSGS
TVHGDRDSLRTLVVNLIDNAIRYTPAGGRVDLRVWHENGRVWLEVADDGPGIPVEERERVLDRFYRRAGQEQPGSGLGLA
IVKAIADRHGAELRLDESARGGLAVRVGLPAAPVAAEETSGNTAGVEP
>Mature_448_residues
MRRQLLITLLGAVLGVFLIGSLATYQTTRGEVDEIMDYHLRQLALSLRAPQYGAQPELGPDDQLFDMVIQVWDEQGLRLY
LSRPHTALPDRAQLGYATVPTAEGDWRTYSIVMGSRVVQVAQPMSHRNRLAAAAALRTLTPLLVILPLLAGLIWYLVGRG
LRPLERLARAVGQRRPDSLAPLAVAGVPDEAQPLVQALNGLLGRLDHAMSAQRAFVADAAHELRTPLAALQLQLQLTERA
GSEAERRAALGELRQGLLRATRVVQQLLTLARQTPDAAAAGAPPAVVDLVELVALVTAELQALAEARGIDLGAEQLDSGS
TVHGDRDSLRTLVVNLIDNAIRYTPAGGRVDLRVWHENGRVWLEVADDGPGIPVEERERVLDRFYRRAGQEQPGSGLGLA
IVKAIADRHGAELRLDESARGGLAVRVGLPAAPVAAEETSGNTAGVEP

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=452, Percent_Identity=32.5221238938053, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1790551, Length=277, Percent_Identity=32.129963898917, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=31.5018315018315, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786783, Length=309, Percent_Identity=31.7152103559871, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=34.1991341991342, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788279, Length=299, Percent_Identity=29.7658862876254, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=30.8035714285714, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789808, Length=302, Percent_Identity=27.8145695364238, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=28.2700421940928, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1787374, Length=282, Percent_Identity=26.9503546099291, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=308, Percent_Identity=29.8701298701299, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI87082128, Length=335, Percent_Identity=25.3731343283582, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=25.4545454545455, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=28.9915966386555, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788713, Length=285, Percent_Identity=25.2631578947368, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=28.6363636363636, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI48994928, Length=246, Percent_Identity=26.0162601626016, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48275; Mature: 48275

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRQLLITLLGAVLGVFLIGSLATYQTTRGEVDEIMDYHLRQLALSLRAPQYGAQPELGP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DDQLFDMVIQVWDEQGLRLYLSRPHTALPDRAQLGYATVPTAEGDWRTYSIVMGSRVVQV
CHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCEECCCCCCCCEEEEEHHHHHHHHH
AQPMSHRNRLAAAAALRTLTPLLVILPLLAGLIWYLVGRGLRPLERLARAVGQRRPDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
PLAVAGVPDEAQPLVQALNGLLGRLDHAMSAQRAFVADAAHELRTPLAALQLQLQLTERA
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
GSEAERRAALGELRQGLLRATRVVQQLLTLARQTPDAAAAGAPPAVVDLVELVALVTAEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QALAEARGIDLGAEQLDSGSTVHGDRDSLRTLVVNLIDNAIRYTPAGGRVDLRVWHENGR
HHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCE
VWLEVADDGPGIPVEERERVLDRFYRRAGQEQPGSGLGLAIVKAIADRHGAELRLDESAR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GGLAVRVGLPAAPVAAEETSGNTAGVEP
CCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRQLLITLLGAVLGVFLIGSLATYQTTRGEVDEIMDYHLRQLALSLRAPQYGAQPELGP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
DDQLFDMVIQVWDEQGLRLYLSRPHTALPDRAQLGYATVPTAEGDWRTYSIVMGSRVVQV
CHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHCCCEECCCCCCCCEEEEEHHHHHHHHH
AQPMSHRNRLAAAAALRTLTPLLVILPLLAGLIWYLVGRGLRPLERLARAVGQRRPDSLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
PLAVAGVPDEAQPLVQALNGLLGRLDHAMSAQRAFVADAAHELRTPLAALQLQLQLTERA
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHC
GSEAERRAALGELRQGLLRATRVVQQLLTLARQTPDAAAAGAPPAVVDLVELVALVTAEL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
QALAEARGIDLGAEQLDSGSTVHGDRDSLRTLVVNLIDNAIRYTPAGGRVDLRVWHENGR
HHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEEEEEECCCE
VWLEVADDGPGIPVEERERVLDRFYRRAGQEQPGSGLGLAIVKAIADRHGAELRLDESAR
EEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCC
GGLAVRVGLPAAPVAAEETSGNTAGVEP
CCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]