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The map label for this gene is 119775927

Identifier: 119775927

GI number: 119775927

Start: 3333758

End: 3336043

Strand: Reverse

Name: 119775927

Synonym: Sama_2795

Alternate gene names: NA

Gene position: 3336043-3333758 (Counterclockwise)

Preceding gene: 119775928

Following gene: 119775926

Centisome position: 77.47

GC content: 58.27

Gene sequence:

>2286_bases
ATGGAAGACAGGGCTATTGCCGTTGAACGGCAGTTTATTGAGGCGCTGGAAACCGGCTCGGTCGGTGCCTTTATCGATAA
TACCCAGGGCTGGGACCATCGCCGTCTCGGGCTCAGTGATGCCGAGTTTGTGGGGATTTTCGAGTCCCAGCTAAAGAGTC
GTTTGCTTGATTTGGAGTCGCGCCGTATGAGGGCGCGCAACGAAGGCTTTTATACCATTGGCTCCTCGGGCCATGAGGGC
AATGCGGCCATTGCCGCAGTGCTCAACACCACCGATATGGCGCTGCTGCATTACCGCAGCGGCGCCTTTATGGTGGAGCG
CAGCCGCCATGAGGCGAGTGAGACCGTGCTGTGGGACATGATGCTCTCCTTCGCGGCTTCCAGCGAAGACCCCATCTCCG
GCGGCCGCCATAAGGTGCTTGGCAGCAAGTCACTCAATATTCCGCCGCAAACCTCCACTATTGCTTCCCATCTGCCCAAG
GCGGTTGGGGTCGCCCTGAGTATTCCGCTTACCGAGCGCTTGGGTGTTGACGGGGTTTTACCCCCTGATGCCATCGCCAT
GTGTAACTTCGGTGATGCCTCGGCCAACCATGCCAGTGCCCAGACCGCTATTAACGCGGCCTGCTGGGCGGCATTTCAGA
ATATTCCCATGCCGCTGATGTTTGTCTGTGAAGACAACGGCATAGGCATTTCTACCCCCACCCCCAAGGGCTGGATTGGG
GCCAATTTCAGCCAAAGACCCGGGCTTAAGTATTTTTGCTGTGATGGGCTGGATTTGCTCGACACCTACAAGGTGGCCAA
AGAGGCGGCCCACTGGTGTCGCAGCCATCGCCAGCCGGTGTTTTTGCATGTGCGTACCGTGCGCCTGATGGGCCATGCCG
GCAGCGATGCCGAGATTGCCTATCTGCCCAAGGCGAAAATTCTTGAAAACGAAGCCCTGGACCCCTTGCTTCGCAGCGCC
GCCATGCTGATAGAGGCGGGCGTACTGAGTGCCGAGCAGATCCTGGCAATGTATCAGGAGCTCAAAGACCGGATTGCTGC
CATTGCCAGAGTGGCGGCTACCCGTCCGAAGCTGACAACGGCAAAAGATGCCATGGCGAGCGTGGTGCCGCCCAAACTCG
CCAATCCCCGCGCGGTAAAAACGCTGGATGAAGAAGCTTTTGCGAGTCTTTTTGCCGCCGACAAGCAGTCCCTCGGCAAA
CCTGTGCATATGGGAAAGCTCATTAACCTGACCCTTACTGAGCTCATGGCGAGCCACGATAATGTGGTTGTCTGTGGTGA
GGACGTGGGCAAAAAGGGCGGCGTGTATCATGTTACTTCGCGGCTGGTGGAGCGCTTTGGCCCCAGCAGGGTCATCAATA
CCCTGCTGGATGAAACCTCCATTTTGGGCCTCGCCACCGGTATGGCCCATAACGGATTGCTGCCCATTCCCGAAATCCAG
TTTCTGGCCTATGTGCATAACGCCGAAGACCAAATTCGCGGCGAGGCGGCTACCTTGCCGTTTTTCTCCAACGGTCAGTA
CACCAACCCCATGGTTATTCGCATCGCGGGTTTGGCGTACCAGAAGGGCTTCGGTGGCCACTTCCATAACGACAACTCCT
TTACCGTGTTTCGCGATATTCCAGGGCTTATCCTCGCCTGTCCATCCAATGGCGCCGATGCCCAGGGGATGCTGAGGGAG
TGCGTGCGTCTTGCCCGTGAGGAGCAGCGGCTGGTGATTTTCCTTGAGCCCATCGCGCTCTACATGACCCGCGACCTGCA
TGAGCCAGGCGACAGCCTGTGGGCGGCACAATATGTGCCCGAGCGTGAAGCAACCCCATTGCCTTTCGGTGAGCCCGGCC
GCTTCGGTGAAGGTAAGGATTTGTGCATTATCAGCTACGGCAATGGTTACTACTTGAGTCGTCAGGCCGAAAAGGCGCTG
GCGGAGGCTGGTATTGACTGCACCCTGGTGGACTTGCGGTATCTTGCGCCGCTCAACGAGGCTGCCATTTGTGATATCGC
CGCCAACTGCCGCCATGTGCTGGTGGTGGATGAGTGTCGCCGCTCAGGCTCTGTGTCTGAAGCCATAGTGACGGCGCTGC
ATGAACGTCTGGGCAGCGCCTGCCCGAAACTTGCCCGCCTTAACGCCGAAGACTGTTTTATTCCGCTGGCCGATGCCGCC
ACCTTGCCGCTGCCGGGTAAAGACAGCATAGTGGCTGCTGCCCTCAAGCTGGTGCAGGGCTCGGATGCTGGCACAGGCAA
GGGCACTGACACAGGCATAGTGATTGGACTGGAGGCATCGGCATGA

Upstream 100 bases:

>100_bases
TCCTGGGTCGTGCCCAGACTGATCTGCAGGCATTTTGCTGATGGGAAAGCGGGGGCCGGGTGCCCCCGCTTTTGACTCGT
TCACCCAGTGAGGGATAAGC

Downstream 100 bases:

>100_bases
ACACAAGTGCAACCAAAGAAAGAGTATTGGTGATAGCCCCGGGCCGCGGTTGTTATAACAAAGAGGAACTGGGCTACCTT
AAGCGTCTTCATGGCGATAA

Product: transketolase, central region

Products: NA

Alternate protein names: Branched-chain alpha-keto acid dehydrogenase E1 component beta chain; BCKDH E1-beta [H]

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MEDRAIAVERQFIEALETGSVGAFIDNTQGWDHRRLGLSDAEFVGIFESQLKSRLLDLESRRMRARNEGFYTIGSSGHEG
NAAIAAVLNTTDMALLHYRSGAFMVERSRHEASETVLWDMMLSFAASSEDPISGGRHKVLGSKSLNIPPQTSTIASHLPK
AVGVALSIPLTERLGVDGVLPPDAIAMCNFGDASANHASAQTAINAACWAAFQNIPMPLMFVCEDNGIGISTPTPKGWIG
ANFSQRPGLKYFCCDGLDLLDTYKVAKEAAHWCRSHRQPVFLHVRTVRLMGHAGSDAEIAYLPKAKILENEALDPLLRSA
AMLIEAGVLSAEQILAMYQELKDRIAAIARVAATRPKLTTAKDAMASVVPPKLANPRAVKTLDEEAFASLFAADKQSLGK
PVHMGKLINLTLTELMASHDNVVVCGEDVGKKGGVYHVTSRLVERFGPSRVINTLLDETSILGLATGMAHNGLLPIPEIQ
FLAYVHNAEDQIRGEAATLPFFSNGQYTNPMVIRIAGLAYQKGFGGHFHNDNSFTVFRDIPGLILACPSNGADAQGMLRE
CVRLAREEQRLVIFLEPIALYMTRDLHEPGDSLWAAQYVPEREATPLPFGEPGRFGEGKDLCIISYGNGYYLSRQAEKAL
AEAGIDCTLVDLRYLAPLNEAAICDIAANCRHVLVVDECRRSGSVSEAIVTALHERLGSACPKLARLNAEDCFIPLADAA
TLPLPGKDSIVAAALKLVQGSDAGTGKGTDTGIVIGLEASA

Sequences:

>Translated_761_residues
MEDRAIAVERQFIEALETGSVGAFIDNTQGWDHRRLGLSDAEFVGIFESQLKSRLLDLESRRMRARNEGFYTIGSSGHEG
NAAIAAVLNTTDMALLHYRSGAFMVERSRHEASETVLWDMMLSFAASSEDPISGGRHKVLGSKSLNIPPQTSTIASHLPK
AVGVALSIPLTERLGVDGVLPPDAIAMCNFGDASANHASAQTAINAACWAAFQNIPMPLMFVCEDNGIGISTPTPKGWIG
ANFSQRPGLKYFCCDGLDLLDTYKVAKEAAHWCRSHRQPVFLHVRTVRLMGHAGSDAEIAYLPKAKILENEALDPLLRSA
AMLIEAGVLSAEQILAMYQELKDRIAAIARVAATRPKLTTAKDAMASVVPPKLANPRAVKTLDEEAFASLFAADKQSLGK
PVHMGKLINLTLTELMASHDNVVVCGEDVGKKGGVYHVTSRLVERFGPSRVINTLLDETSILGLATGMAHNGLLPIPEIQ
FLAYVHNAEDQIRGEAATLPFFSNGQYTNPMVIRIAGLAYQKGFGGHFHNDNSFTVFRDIPGLILACPSNGADAQGMLRE
CVRLAREEQRLVIFLEPIALYMTRDLHEPGDSLWAAQYVPEREATPLPFGEPGRFGEGKDLCIISYGNGYYLSRQAEKAL
AEAGIDCTLVDLRYLAPLNEAAICDIAANCRHVLVVDECRRSGSVSEAIVTALHERLGSACPKLARLNAEDCFIPLADAA
TLPLPGKDSIVAAALKLVQGSDAGTGKGTDTGIVIGLEASA
>Mature_761_residues
MEDRAIAVERQFIEALETGSVGAFIDNTQGWDHRRLGLSDAEFVGIFESQLKSRLLDLESRRMRARNEGFYTIGSSGHEG
NAAIAAVLNTTDMALLHYRSGAFMVERSRHEASETVLWDMMLSFAASSEDPISGGRHKVLGSKSLNIPPQTSTIASHLPK
AVGVALSIPLTERLGVDGVLPPDAIAMCNFGDASANHASAQTAINAACWAAFQNIPMPLMFVCEDNGIGISTPTPKGWIG
ANFSQRPGLKYFCCDGLDLLDTYKVAKEAAHWCRSHRQPVFLHVRTVRLMGHAGSDAEIAYLPKAKILENEALDPLLRSA
AMLIEAGVLSAEQILAMYQELKDRIAAIARVAATRPKLTTAKDAMASVVPPKLANPRAVKTLDEEAFASLFAADKQSLGK
PVHMGKLINLTLTELMASHDNVVVCGEDVGKKGGVYHVTSRLVERFGPSRVINTLLDETSILGLATGMAHNGLLPIPEIQ
FLAYVHNAEDQIRGEAATLPFFSNGQYTNPMVIRIAGLAYQKGFGGHFHNDNSFTVFRDIPGLILACPSNGADAQGMLRE
CVRLAREEQRLVIFLEPIALYMTRDLHEPGDSLWAAQYVPEREATPLPFGEPGRFGEGKDLCIISYGNGYYLSRQAEKAL
AEAGIDCTLVDLRYLAPLNEAAICDIAANCRHVLVVDECRRSGSVSEAIVTALHERLGSACPKLARLNAEDCFIPLADAA
TLPLPGKDSIVAAALKLVQGSDAGTGKGTDTGIVIGLEASA

Specific function: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components:branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltran

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557353, Length=297, Percent_Identity=28.6195286195286, Blast_Score=113, Evalue=7e-25,
Organism=Homo sapiens, GI34101272, Length=297, Percent_Identity=28.6195286195286, Blast_Score=113, Evalue=7e-25,
Organism=Homo sapiens, GI156564403, Length=277, Percent_Identity=24.5487364620939, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4885543, Length=328, Percent_Identity=23.1707317073171, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI4505685, Length=210, Percent_Identity=25.2380952380952, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI291084744, Length=210, Percent_Identity=25.2380952380952, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI291084742, Length=210, Percent_Identity=25.2380952380952, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI291084858, Length=272, Percent_Identity=23.1617647058824, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI258645172, Length=318, Percent_Identity=23.5849056603774, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI11386135, Length=319, Percent_Identity=23.5109717868339, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI291084757, Length=157, Percent_Identity=26.7515923566879, Blast_Score=73, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538422, Length=275, Percent_Identity=28.3636363636364, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17506935, Length=291, Percent_Identity=28.8659793814433, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86563355, Length=349, Percent_Identity=26.9340974212034, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI86563357, Length=349, Percent_Identity=26.9340974212034, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536047, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32564172, Length=232, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319698, Length=305, Percent_Identity=29.5081967213115, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6321026, Length=160, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI160714832, Length=308, Percent_Identity=27.9220779220779, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI160714828, Length=308, Percent_Identity=27.9220779220779, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21358145, Length=365, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24650940, Length=365, Percent_Identity=26.027397260274, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355903, Length=321, Percent_Identity=23.6760124610592, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =1.2.4.4 [H]

Molecular weight: Translated: 81994; Mature: 81994

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDRAIAVERQFIEALETGSVGAFIDNTQGWDHRRLGLSDAEFVGIFESQLKSRLLDLES
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RRMRARNEGFYTIGSSGHEGNAAIAAVLNTTDMALLHYRSGAFMVERSRHEASETVLWDM
HHHHHCCCCCEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCHHHHHHHHHHHH
MLSFAASSEDPISGGRHKVLGSKSLNIPPQTSTIASHLPKAVGVALSIPLTERLGVDGVL
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCEEEECCCHHHCCCCCCC
PPDAIAMCNFGDASANHASAQTAINAACWAAFQNIPMPLMFVCEDNGIGISTPTPKGWIG
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCC
ANFSQRPGLKYFCCDGLDLLDTYKVAKEAAHWCRSHRQPVFLHVRTVRLMGHAGSDAEIA
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEE
YLPKAKILENEALDPLLRSAAMLIEAGVLSAEQILAMYQELKDRIAAIARVAATRPKLTT
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AKDAMASVVPPKLANPRAVKTLDEEAFASLFAADKQSLGKPVHMGKLINLTLTELMASHD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
NVVVCGEDVGKKGGVYHVTSRLVERFGPSRVINTLLDETSILGLATGMAHNGLLPIPEIQ
CEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FLAYVHNAEDQIRGEAATLPFFSNGQYTNPMVIRIAGLAYQKGFGGHFHNDNSFTVFRDI
EHHEECCCHHHHCCCEEECCEECCCCCCCCEEEEEECHHHCCCCCCCCCCCCCEEEEECC
PGLILACPSNGADAQGMLRECVRLAREEQRLVIFLEPIALYMTRDLHEPGDSLWAAQYVP
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHCCC
EREATPLPFGEPGRFGEGKDLCIISYGNGYYLSRQAEKALAEAGIDCTLVDLRYLAPLNE
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHCCCCEEEEEHHHHCCCCC
AAICDIAANCRHVLVVDECRRSGSVSEAIVTALHERLGSACPKLARLNAEDCFIPLADAA
HHEEEHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCC
TLPLPGKDSIVAAALKLVQGSDAGTGKGTDTGIVIGLEASA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MEDRAIAVERQFIEALETGSVGAFIDNTQGWDHRRLGLSDAEFVGIFESQLKSRLLDLES
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
RRMRARNEGFYTIGSSGHEGNAAIAAVLNTTDMALLHYRSGAFMVERSRHEASETVLWDM
HHHHHCCCCCEEECCCCCCCCEEEEEEECCCCEEEEEECCCCEEEECCHHHHHHHHHHHH
MLSFAASSEDPISGGRHKVLGSKSLNIPPQTSTIASHLPKAVGVALSIPLTERLGVDGVL
HHHHHCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCEEEECCCHHHCCCCCCC
PPDAIAMCNFGDASANHASAQTAINAACWAAFQNIPMPLMFVCEDNGIGISTPTPKGWIG
CCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCC
ANFSQRPGLKYFCCDGLDLLDTYKVAKEAAHWCRSHRQPVFLHVRTVRLMGHAGSDAEIA
CCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCCEEE
YLPKAKILENEALDPLLRSAAMLIEAGVLSAEQILAMYQELKDRIAAIARVAATRPKLTT
ECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
AKDAMASVVPPKLANPRAVKTLDEEAFASLFAADKQSLGKPVHMGKLINLTLTELMASHD
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCC
NVVVCGEDVGKKGGVYHVTSRLVERFGPSRVINTLLDETSILGLATGMAHNGLLPIPEIQ
CEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FLAYVHNAEDQIRGEAATLPFFSNGQYTNPMVIRIAGLAYQKGFGGHFHNDNSFTVFRDI
EHHEECCCHHHHCCCEEECCEECCCCCCCCEEEEEECHHHCCCCCCCCCCCCCEEEEECC
PGLILACPSNGADAQGMLRECVRLAREEQRLVIFLEPIALYMTRDLHEPGDSLWAAQYVP
CCEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCHHHHHHCCC
EREATPLPFGEPGRFGEGKDLCIISYGNGYYLSRQAEKALAEAGIDCTLVDLRYLAPLNE
CCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECHHHHHHHHHCCCCEEEEEHHHHCCCCC
AAICDIAANCRHVLVVDECRRSGSVSEAIVTALHERLGSACPKLARLNAEDCFIPLADAA
HHEEEHHCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEECCCC
TLPLPGKDSIVAAALKLVQGSDAGTGKGTDTGIVIGLEASA
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA