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The map label for this gene is mmgC [H]

Identifier: 119775928

GI number: 119775928

Start: 3336103

End: 3337278

Strand: Reverse

Name: mmgC [H]

Synonym: Sama_2796

Alternate gene names: 119775928

Gene position: 3337278-3336103 (Counterclockwise)

Preceding gene: 119775934

Following gene: 119775927

Centisome position: 77.5

GC content: 56.97

Gene sequence:

>1176_bases
ATGGCCCGTGTGCAATTTGACTGGCAAGACCCACTGAATTTCAACTCTCTGCTGACCGAAGAAGAGCGGATGATCCGCGA
TATGGTGCACGAGTATGCTCAGGATAAATTGATGGCGCGGGTGCTGATGGCGAACCGTGACGAACATTTCGACCGTGAAA
TTATGAACGAGCTGGGTGAACTGGGACTGCTTGGCGCTACCTTGCCGGAAGAATACGGCTGCGCCAATGCCAACTATGTA
AGTTATGGTCTGGTGGCCCGTGAAATTGAGCGGGTCGACAGTGGTTATCGTTCCGCCATGAGCGTGCAGTCATCCCTGGT
AATGCACCCCATCTACACCTATGGCACTGAAGCCCAGCGTCGTAAATATCTGCCTAAGCTTGCCACCGGTGAGTGGGTGG
GCTGCTTTGGTCTGACCGAGCCGGATGTGGGCTCAGACCCTGCCGGCATGAAAACCCGCGCAGAGCGTATCGACGGCGGT
TATCGCATTACCGGCGCGAAGATGTGGATCACCAACTCACCCATTGCCGATGTGTTTGTGGTGTGGGCCAAGCTTGATGG
TGCCATCCGCGGCTTCGTGCTTGAGAAGGGCATGAAGGGCCTGTCGGCGCCCAAGATTGAGGGTAAATTCTCCCTGCGCG
CCTCCATTACCGGCGAAATCGTGATGGACAATGTGGAAGTGGGTGAAGATGCGCTGCTGCCCAATGTGGAAGGTCTAAAA
GGCCCCTTTGGTTGCCTGAACAAGGCGCGCTATGGCATCGCCTGGGGCGCCCTGGGGGCTGCCGAATTCTGTTGGCATGC
GGCCCGTCAGTATGGCCTCGATCGTATTCAGTTCAACCGACCGCTCGCGGCCAATCAGCTGTATCAGAAGAAACTGGCCG
ATATGCAAACCGAGATCACCACGGGTCTCTTTGCCTGCCTGCAGGCCGGGCGCCTGATGGACGTCGACGCCCTGCCGGTG
GAAGCCATCTCCCTGATTAAACGCAATTCCTGCGGCAAAGCCCTGGACATTGCCCGCATCGCCCGCGATATGCACGGCGG
TAATGGTATCAGCGACGAATTCCATGTAATACGCCATGTGATGAACCTCGAAGCGGTGAACACTTACGAGGGGACCCACG
ACATCCATGCCCTGATCCTGGGTCGTGCCCAGACTGATCTGCAGGCATTTTGCTGA

Upstream 100 bases:

>100_bases
GCTAGTGCAAATCACAAGTGGCGCTCTGGTCTCCCGTGTTGGCCATACAAGCCGCCTGCAAACCCGTTCAAACAATAAGA
CTCAATGAAAGGACTACCCT

Downstream 100 bases:

>100_bases
TGGGAAAGCGGGGGCCGGGTGCCCCCGCTTTTGACTCGTTCACCCAGTGAGGGATAAGCATGGAAGACAGGGCTATTGCC
GTTGAACGGCAGTTTATTGA

Product: acyl-CoA dehydrogenase-like protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MARVQFDWQDPLNFNSLLTEEERMIRDMVHEYAQDKLMARVLMANRDEHFDREIMNELGELGLLGATLPEEYGCANANYV
SYGLVAREIERVDSGYRSAMSVQSSLVMHPIYTYGTEAQRRKYLPKLATGEWVGCFGLTEPDVGSDPAGMKTRAERIDGG
YRITGAKMWITNSPIADVFVVWAKLDGAIRGFVLEKGMKGLSAPKIEGKFSLRASITGEIVMDNVEVGEDALLPNVEGLK
GPFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRIQFNRPLAANQLYQKKLADMQTEITTGLFACLQAGRLMDVDALPV
EAISLIKRNSCGKALDIARIARDMHGGNGISDEFHVIRHVMNLEAVNTYEGTHDIHALILGRAQTDLQAFC

Sequences:

>Translated_391_residues
MARVQFDWQDPLNFNSLLTEEERMIRDMVHEYAQDKLMARVLMANRDEHFDREIMNELGELGLLGATLPEEYGCANANYV
SYGLVAREIERVDSGYRSAMSVQSSLVMHPIYTYGTEAQRRKYLPKLATGEWVGCFGLTEPDVGSDPAGMKTRAERIDGG
YRITGAKMWITNSPIADVFVVWAKLDGAIRGFVLEKGMKGLSAPKIEGKFSLRASITGEIVMDNVEVGEDALLPNVEGLK
GPFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRIQFNRPLAANQLYQKKLADMQTEITTGLFACLQAGRLMDVDALPV
EAISLIKRNSCGKALDIARIARDMHGGNGISDEFHVIRHVMNLEAVNTYEGTHDIHALILGRAQTDLQAFC
>Mature_390_residues
ARVQFDWQDPLNFNSLLTEEERMIRDMVHEYAQDKLMARVLMANRDEHFDREIMNELGELGLLGATLPEEYGCANANYVS
YGLVAREIERVDSGYRSAMSVQSSLVMHPIYTYGTEAQRRKYLPKLATGEWVGCFGLTEPDVGSDPAGMKTRAERIDGGY
RITGAKMWITNSPIADVFVVWAKLDGAIRGFVLEKGMKGLSAPKIEGKFSLRASITGEIVMDNVEVGEDALLPNVEGLKG
PFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRIQFNRPLAANQLYQKKLADMQTEITTGLFACLQAGRLMDVDALPVE
AISLIKRNSCGKALDIARIARDMHGGNGISDEFHVIRHVMNLEAVNTYEGTHDIHALILGRAQTDLQAFC

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=392, Percent_Identity=68.8775510204082, Blast_Score=558, Evalue=1e-159,
Organism=Homo sapiens, GI7669494, Length=372, Percent_Identity=68.010752688172, Blast_Score=522, Evalue=1e-148,
Organism=Homo sapiens, GI226958412, Length=380, Percent_Identity=31.5789473684211, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=30.958904109589, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI4557233, Length=370, Percent_Identity=29.7297297297297, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI226958414, Length=349, Percent_Identity=31.8051575931232, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4557231, Length=384, Percent_Identity=27.6041666666667, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI187960098, Length=384, Percent_Identity=27.6041666666667, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI21361497, Length=342, Percent_Identity=30.9941520467836, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI76496475, Length=338, Percent_Identity=31.3609467455621, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4557235, Length=338, Percent_Identity=31.3609467455621, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=26.1780104712042, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI7656849, Length=382, Percent_Identity=26.4397905759162, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1786223, Length=379, Percent_Identity=25.065963060686, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=26.1213720316623, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=389, Percent_Identity=60.9254498714653, Blast_Score=494, Evalue=1e-140,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=32.7176781002639, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=31.9672131147541, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=372, Percent_Identity=30.6451612903226, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71985184, Length=386, Percent_Identity=29.5336787564767, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=35.2313167259786, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17569725, Length=374, Percent_Identity=27.807486631016, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=31.6831683168317, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=27.4666666666667, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=34.7826086956522, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17570075, Length=374, Percent_Identity=26.4705882352941, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=27.3062730627306, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=377, Percent_Identity=23.6074270557029, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=250, Percent_Identity=24.4, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562446, Length=261, Percent_Identity=28.735632183908, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=354, Percent_Identity=22.8813559322034, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920834, Length=391, Percent_Identity=63.9386189258312, Blast_Score=494, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=30.8707124010554, Blast_Score=175, Evalue=5e-44,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=29.0322580645161, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=30.0268096514745, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24660351, Length=374, Percent_Identity=29.6791443850267, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=28.5333333333333, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI281363737, Length=387, Percent_Identity=27.6485788113695, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 43388; Mature: 43257

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARVQFDWQDPLNFNSLLTEEERMIRDMVHEYAQDKLMARVLMANRDEHFDREIMNELGE
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGLLGATLPEEYGCANANYVSYGLVAREIERVDSGYRSAMSVQSSLVMHPIYTYGTEAQR
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RKYLPKLATGEWVGCFGLTEPDVGSDPAGMKTRAERIDGGYRITGAKMWITNSPIADVFV
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCHHHHHH
VWAKLDGAIRGFVLEKGMKGLSAPKIEGKFSLRASITGEIVMDNVEVGEDALLPNVEGLK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCHHCCCCCCCCC
GPFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRIQFNRPLAANQLYQKKLADMQTEIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHH
TGLFACLQAGRLMDVDALPVEAISLIKRNSCGKALDIARIARDMHGGNGISDEFHVIRHV
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNLEAVNTYEGTHDIHALILGRAQTDLQAFC
HHHHHHCCCCCCHHHHHHEECCCHHHHHHCC
>Mature Secondary Structure 
ARVQFDWQDPLNFNSLLTEEERMIRDMVHEYAQDKLMARVLMANRDEHFDREIMNELGE
CEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGLLGATLPEEYGCANANYVSYGLVAREIERVDSGYRSAMSVQSSLVMHPIYTYGTEAQR
CCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RKYLPKLATGEWVGCFGLTEPDVGSDPAGMKTRAERIDGGYRITGAKMWITNSPIADVFV
HHCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHCCCCEEEEEEEEEEECCCHHHHHH
VWAKLDGAIRGFVLEKGMKGLSAPKIEGKFSLRASITGEIVMDNVEVGEDALLPNVEGLK
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCCHHCCCCCCCCC
GPFGCLNKARYGIAWGALGAAEFCWHAARQYGLDRIQFNRPLAANQLYQKKLADMQTEIT
CCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHH
TGLFACLQAGRLMDVDALPVEAISLIKRNSCGKALDIARIARDMHGGNGISDEFHVIRHV
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNLEAVNTYEGTHDIHALILGRAQTDLQAFC
HHHHHHCCCCCCHHHHHHEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]