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The map label for this gene is pheA [H]

Identifier: 119774035

GI number: 119774035

Start: 1086123

End: 1088102

Strand: Reverse

Name: pheA [H]

Synonym: Sama_0898

Alternate gene names: 119774035

Gene position: 1088102-1086123 (Counterclockwise)

Preceding gene: 119774036

Following gene: 119774024

Centisome position: 25.27

GC content: 55.3

Gene sequence:

>1980_bases
ATGGAGAAACCACAGCCCCTGAGTGAAACCCGGGAGCAGATCACCGACATCGACAACACAGTGCTGCAATTGCTGGCACG
GCGTCGGGAGCTCAGCCTCGAAGTCGCTCGCAGTAAAGAAGTGGATGTGCGCCCCGTGCGCGATACTCAGCGCGAGCGCG
AGCTGTTGTCGAGACTGGTACAAAAAGGCCGCGAGCAGGGGCTGGATCCGCACTTTGTTATGCAGCTATATCAAAGCATT
ATCGAAGACTCAGTACTCAACCAGCAGGCCTATCTCCATGGCCGGGCCAACCCGGAAACCCAAAAACAACAGTATTGCAT
TGCTTATCTGGGTGCCAGAGGCTCCTACTCATACCTCGCCGCCAATCGATACTGTCAACGCCGCCAGGTAGACATGGTGG
ATCTGGGCTGTCAAAGCTTCGATGAAATAGTTCATGCAGTGGAATCCGGACATGCCGATTACGGTTTCCTACCAATTGAA
AACACTTCCTCTGGCTCCATTAACGAAGTCTATGATGTGCTTCAGCACACCAGCCTGGCCATTGTGGGTGAAACCACCAT
CGAGGTGGGTCATTGCCTGCTTGCGAAGCCCGGTACCAAGGCATCGGATATCAAGACCCTGTATGCCCATCCGCAGCCAA
TCAGCCAATGCAGCCGCTATCTGGCACGCCACCCCGGTCTTAGACTCGAATACTGCGCCTCCAGCGCCGAAGCCATGGAA
AAGGTGCAGGCTGCTGACAGCAAGGATGTCGCCGCCATCGGCAGCGCCGAAGGGGGGGGCCTGTACCAGCTGGAAGCAAT
CGAAAAGGGACTCGCCAATCAAAAGGTCAACCAAAGCCGCTTTATTGTAGTAGCCCGTAAAGCCGTGGCAGTGCCCGAAC
AGTTGCCCGCCAAATGCACCCTCATTATGGCAACAGGCCAAAAGCCAGGAGCCCTAGTAGAAGCCTTGCTGGTGCTCAAG
GCCAACAACCTTAATATGAGCAAGCTCGAGAGCCGCCCGATCCCAGGTACGCCCTGGGAGGAAATGTTTTATCTCGATAT
CGACGCCAACCTGGCCAGTGTCCCTATGCAACTGGCGCTGAAAGAGCTTGAACGCATTACCCGTTTTATTAAGGTGCTGG
GTTGCTACCCCTGTGAAACAGTAGCACCCACGCAGCTATCCAACGCCCAGCTGTTAATCGAGCCCGAGCATTTCCGTACC
GATGCGCCAGAGCCAGCCGCCGCACAGGCCCGGGATGGCGATTCGGTACCTGCCCGCCATAGTCTGGGGTACAAAGAAAC
CGTCAGCGAAGTACAAGCGGGCGCCTTGCTCATCGGCAATGGTCATTCGGGTGCACTCGCGATGCTTTCGTTACCTGATA
CTCTTGAAGGGTTCGAACCCTTCCTTAAGCAGCTAAAGGCGGCCGGTTTTGCTGGCCTTGTGCTGGATAATCTGTCTGAG
CGACCAGATCCCGCCAAAGCACTGGATGCCTGCACCAAGGCCGCTGAAAAGTTTGGCCTCATCACCGCTGCGGCAGTGAA
CAGGGAAGATGAGCTTGAGCATGCCATCTCCCGGGTCGAACTTATCCTGATAAGGGGCAAGCAAATGTTCAATCAGCCCC
TGCTGGAACGCCTTGGTAAGCTGCATCTACCTGTGGTGCTTGAACGCAATACCATGGCCGATATTGACGAACTCCTGGCC
GCTGCCGATACCATTCTGGCAGAAGGTAACCAACAGCTGATGCTGTGTGAGTCAGGAGTCAGCAGCTTTAAGAGCAGCAC
ACTTGCCACCCTGGATTTAGCCGGCTTAGTGGAGCTGAAAGCCAGAAGTCATCTGCCGGTGCTGGTCAACCCCAGCTATG
CAGTAACCCCTGAAGCCTGTCCACGTCAGGCTAAAGCGGTTAAACGTCTCGGGGCCGATGGATTGTTGCTTGAGGTGTCG
CTGGACACCTCGATGGCTGACAGTTATTTGGGTGAAACTTTGCGGCAGTTTTTTGTGTAA

Upstream 100 bases:

>100_bases
GGATTTTCTGTGTAAAAACGAAAGTGAAAATTCAAAGCCTCCCACCACCGGGAGGCTTTTTTGTTCTTAGGCGATGCAGT
TAATACCAACAGAGGTCAGC

Downstream 100 bases:

>100_bases
AGGATAGTAGAGTCGTAATGCAAAAGGGGCCAACAGGCCCCCTTTTGATTAACCGGATAGCGCAATGCCCTTACTTCAAG
CTATCAATCGCTTCGTCAGA

Product: prephenate dehydratase / chorismate mutase / phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 659; Mature: 659

Protein sequence:

>659_residues
MEKPQPLSETREQITDIDNTVLQLLARRRELSLEVARSKEVDVRPVRDTQRERELLSRLVQKGREQGLDPHFVMQLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAANRYCQRRQVDMVDLGCQSFDEIVHAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLAKPGTKASDIKTLYAHPQPISQCSRYLARHPGLRLEYCASSAEAME
KVQAADSKDVAAIGSAEGGGLYQLEAIEKGLANQKVNQSRFIVVARKAVAVPEQLPAKCTLIMATGQKPGALVEALLVLK
ANNLNMSKLESRPIPGTPWEEMFYLDIDANLASVPMQLALKELERITRFIKVLGCYPCETVAPTQLSNAQLLIEPEHFRT
DAPEPAAAQARDGDSVPARHSLGYKETVSEVQAGALLIGNGHSGALAMLSLPDTLEGFEPFLKQLKAAGFAGLVLDNLSE
RPDPAKALDACTKAAEKFGLITAAAVNREDELEHAISRVELILIRGKQMFNQPLLERLGKLHLPVVLERNTMADIDELLA
AADTILAEGNQQLMLCESGVSSFKSSTLATLDLAGLVELKARSHLPVLVNPSYAVTPEACPRQAKAVKRLGADGLLLEVS
LDTSMADSYLGETLRQFFV

Sequences:

>Translated_659_residues
MEKPQPLSETREQITDIDNTVLQLLARRRELSLEVARSKEVDVRPVRDTQRERELLSRLVQKGREQGLDPHFVMQLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAANRYCQRRQVDMVDLGCQSFDEIVHAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLAKPGTKASDIKTLYAHPQPISQCSRYLARHPGLRLEYCASSAEAME
KVQAADSKDVAAIGSAEGGGLYQLEAIEKGLANQKVNQSRFIVVARKAVAVPEQLPAKCTLIMATGQKPGALVEALLVLK
ANNLNMSKLESRPIPGTPWEEMFYLDIDANLASVPMQLALKELERITRFIKVLGCYPCETVAPTQLSNAQLLIEPEHFRT
DAPEPAAAQARDGDSVPARHSLGYKETVSEVQAGALLIGNGHSGALAMLSLPDTLEGFEPFLKQLKAAGFAGLVLDNLSE
RPDPAKALDACTKAAEKFGLITAAAVNREDELEHAISRVELILIRGKQMFNQPLLERLGKLHLPVVLERNTMADIDELLA
AADTILAEGNQQLMLCESGVSSFKSSTLATLDLAGLVELKARSHLPVLVNPSYAVTPEACPRQAKAVKRLGADGLLLEVS
LDTSMADSYLGETLRQFFV
>Mature_659_residues
MEKPQPLSETREQITDIDNTVLQLLARRRELSLEVARSKEVDVRPVRDTQRERELLSRLVQKGREQGLDPHFVMQLYQSI
IEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLAANRYCQRRQVDMVDLGCQSFDEIVHAVESGHADYGFLPIE
NTSSGSINEVYDVLQHTSLAIVGETTIEVGHCLLAKPGTKASDIKTLYAHPQPISQCSRYLARHPGLRLEYCASSAEAME
KVQAADSKDVAAIGSAEGGGLYQLEAIEKGLANQKVNQSRFIVVARKAVAVPEQLPAKCTLIMATGQKPGALVEALLVLK
ANNLNMSKLESRPIPGTPWEEMFYLDIDANLASVPMQLALKELERITRFIKVLGCYPCETVAPTQLSNAQLLIEPEHFRT
DAPEPAAAQARDGDSVPARHSLGYKETVSEVQAGALLIGNGHSGALAMLSLPDTLEGFEPFLKQLKAAGFAGLVLDNLSE
RPDPAKALDACTKAAEKFGLITAAAVNREDELEHAISRVELILIRGKQMFNQPLLERLGKLHLPVVLERNTMADIDELLA
AADTILAEGNQQLMLCESGVSSFKSSTLATLDLAGLVELKARSHLPVLVNPSYAVTPEACPRQAKAVKRLGADGLLLEVS
LDTSMADSYLGETLRQFFV

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=55.1813471502591, Blast_Score=431, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6324013, Length=289, Percent_Identity=24.9134948096886, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 72069; Mature: 72069

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKPQPLSETREQITDIDNTVLQLLARRRELSLEVARSKEVDVRPVRDTQRERELLSRLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
QKGREQGLDPHFVMQLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEHHEECCCCCCHHHH
ANRYCQRRQVDMVDLGCQSFDEIVHAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLA
HHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVGHCLLAKPGTKASDIKTLYAHPQPISQCSRYLARHPGLRLEYCASSAEAME
EEECCHHHHCCEEEECCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCEEHHHHCHHHHHH
KVQAADSKDVAAIGSAEGGGLYQLEAIEKGLANQKVNQSRFIVVARKAVAVPEQLPAKCT
HHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCEEE
LIMATGQKPGALVEALLVLKANNLNMSKLESRPIPGTPWEEMFYLDIDANLASVPMQLAL
EEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHEEEEEECCCHHHHHHHHHH
KELERITRFIKVLGCYPCETVAPTQLSNAQLLIEPEHFRTDAPEPAAAQARDGDSVPARH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHH
SLGYKETVSEVQAGALLIGNGHSGALAMLSLPDTLEGFEPFLKQLKAAGFAGLVLDNLSE
CCCHHHHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCC
RPDPAKALDACTKAAEKFGLITAAAVNREDELEHAISRVELILIRGKQMFNQPLLERLGK
CCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCC
LHLPVVLERNTMADIDELLAAADTILAEGNQQLMLCESGVSSFKSSTLATLDLAGLVELK
CCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHH
ARSHLPVLVNPSYAVTPEACPRQAKAVKRLGADGLLLEVSLDTSMADSYLGETLRQFFV
HCCCCCEEECCCCEECCHHCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKPQPLSETREQITDIDNTVLQLLARRRELSLEVARSKEVDVRPVRDTQRERELLSRLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
QKGREQGLDPHFVMQLYQSIIEDSVLNQQAYLHGRANPETQKQQYCIAYLGARGSYSYLA
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHEECCCCCCHHHHHEEHHEECCCCCCHHHH
ANRYCQRRQVDMVDLGCQSFDEIVHAVESGHADYGFLPIENTSSGSINEVYDVLQHTSLA
HHHHHHHHCCCHHHHCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHCCEE
IVGETTIEVGHCLLAKPGTKASDIKTLYAHPQPISQCSRYLARHPGLRLEYCASSAEAME
EEECCHHHHCCEEEECCCCCHHHHHHEECCCCCHHHHHHHHHHCCCCEEHHHHCHHHHHH
KVQAADSKDVAAIGSAEGGGLYQLEAIEKGLANQKVNQSRFIVVARKAVAVPEQLPAKCT
HHHHCCCCCEEEECCCCCCCEEEHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCCCCEEE
LIMATGQKPGALVEALLVLKANNLNMSKLESRPIPGTPWEEMFYLDIDANLASVPMQLAL
EEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCCHHHEEEEEECCCHHHHHHHHHH
KELERITRFIKVLGCYPCETVAPTQLSNAQLLIEPEHFRTDAPEPAAAQARDGDSVPARH
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCCCCCCCCCCCHH
SLGYKETVSEVQAGALLIGNGHSGALAMLSLPDTLEGFEPFLKQLKAAGFAGLVLDNLSE
CCCHHHHHHHHHCCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCC
RPDPAKALDACTKAAEKFGLITAAAVNREDELEHAISRVELILIRGKQMFNQPLLERLGK
CCCHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHEECCHHHHHHHHHHHHCC
LHLPVVLERNTMADIDELLAAADTILAEGNQQLMLCESGVSSFKSSTLATLDLAGLVELK
CCCCEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCHHHHHHHHHHHHHH
ARSHLPVLVNPSYAVTPEACPRQAKAVKRLGADGLLLEVSLDTSMADSYLGETLRQFFV
HCCCCCEEECCCCEECCHHCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]