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The map label for this gene is purC

Identifier: 119773631

GI number: 119773631

Start: 602790

End: 603893

Strand: Reverse

Name: purC

Synonym: Sama_0491

Alternate gene names: 119773631

Gene position: 603893-602790 (Counterclockwise)

Preceding gene: 119773632

Following gene: 119773630

Centisome position: 14.02

GC content: 54.35

Gene sequence:

>1104_bases
ATGAGTCTTGCTGATTCCGTACTGGCCGTGAACAACGACCTGCCTATCCGTACCGACAAACCCGTGCACAGCGGTAAGGT
TCGCAGCGTTTATTGGCTGACCGAGGCCGACAGCGCCCGCCTTATCCGTGAACGCGGCTACGATGTGCCTGCCGACACGC
CGCTGGCCATCATGGTGATCTCTGACCGTATCTCCGCCTTCGATTGCATCTTCCACGGTGAAGGCGATCTGCGTGGTATT
CCCGGTAAGGGTGCGGCCCTCAATGCCATCTCCAACCACTGGTTTGGTCTGTTTAAAGAAAACGGCCTGGCAGACAGTCA
TATCCTCGACATCCCCCATCCTTTTGTGTGGATTGTGCAAAAGGCCCGACCCATTAAAGTGGAAGCCATTATTCGCCAGT
ACATCACAGGCTCCATGTGGCGCGCCTACCAAAAAGGTGAGCGGGTGTTCTGCGGTATCACATTGCCTGAGGGGCTGCAG
AAGGATCAGAAACTGCCTGAGCTTTTGATCACACCGTCCACCAAGGGCATCCTCACCGGTATTCCCGGCGTGCCAGAACA
GGATGACGTAAACATCAGCCGCGCCGATATCGAAGCTAACTTCGAAGCCTTTGGTTTTGAAAAGAAAGAAGATATCGACC
TCTATGAAAAGCTTTTGAAAGAAGGCTTTGGGGTGATTTCCGAGGCGCTGGCAAAGCTTGACCAGGTGTTTGTGGATACC
AAGTTTGAGTTTGGCTATGTCACCGACAGCAACGGTAATTCCAAGCTGATTTACATGGATGAAGTGGGCACACCGGATTC
TTCCCGTATTTGGGACGGCGCCGCCTACCGCGACGGCAAGATTGTGGAAAACTCCAAAGAAGGTTTCCGCCAGTTCCTGC
TGAACCACTTCCCGGATCCGGACATCCTGCTCAACAAAGACCGGATGCCTGAGCGTGAAGCCCTGGCCCGCGACAACGCC
CTGCCGCTGGATGCCATGATGAACGTATCCCGCACCTACACAGGTATCGCCGAGAAGGTCACCGGCCGCAAGATTGAGCT
GTCCGACAATCCCAAGGCGGAAATCATCGCCATCCTCAAAGAGCAGTACGCTTTGGTGGATTAA

Upstream 100 bases:

>100_bases
ATCATGCGCTGCAACACCCAATACCCCGGGAAACAGGCACAAACCACAATAAGCCTGCCCGATTTAACCCTTACCCCACA
CATTCAGAGGAATACTCGTC

Downstream 100 bases:

>100_bases
GGCTTACGCGCTCTGAAACGGCGCGCTTAATTTCTCGCAAGAAACCCCGGCCGATGTCGGGTTTTTTATTTCGCTGACAA
CCTTAAGCCTGCCCAAGCCA

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSLADSVLAVNNDLPIRTDKPVHSGKVRSVYWLTEADSARLIRERGYDVPADTPLAIMVISDRISAFDCIFHGEGDLRGI
PGKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQKARPIKVEAIIRQYITGSMWRAYQKGERVFCGITLPEGLQ
KDQKLPELLITPSTKGILTGIPGVPEQDDVNISRADIEANFEAFGFEKKEDIDLYEKLLKEGFGVISEALAKLDQVFVDT
KFEFGYVTDSNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKIVENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNA
LPLDAMMNVSRTYTGIAEKVTGRKIELSDNPKAEIIAILKEQYALVD

Sequences:

>Translated_367_residues
MSLADSVLAVNNDLPIRTDKPVHSGKVRSVYWLTEADSARLIRERGYDVPADTPLAIMVISDRISAFDCIFHGEGDLRGI
PGKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQKARPIKVEAIIRQYITGSMWRAYQKGERVFCGITLPEGLQ
KDQKLPELLITPSTKGILTGIPGVPEQDDVNISRADIEANFEAFGFEKKEDIDLYEKLLKEGFGVISEALAKLDQVFVDT
KFEFGYVTDSNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKIVENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNA
LPLDAMMNVSRTYTGIAEKVTGRKIELSDNPKAEIIAILKEQYALVD
>Mature_366_residues
SLADSVLAVNNDLPIRTDKPVHSGKVRSVYWLTEADSARLIRERGYDVPADTPLAIMVISDRISAFDCIFHGEGDLRGIP
GKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQKARPIKVEAIIRQYITGSMWRAYQKGERVFCGITLPEGLQK
DQKLPELLITPSTKGILTGIPGVPEQDDVNISRADIEANFEAFGFEKKEDIDLYEKLLKEGFGVISEALAKLDQVFVDTK
FEFGYVTDSNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKIVENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNAL
PLDAMMNVSRTYTGIAEKVTGRKIELSDNPKAEIIAILKEQYALVD

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=300, Percent_Identity=32.3333333333333, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PUR7_SHEAM (A1S2U5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926371.1
- ProteinModelPortal:   A1S2U5
- SMR:   A1S2U5
- STRING:   A1S2U5
- GeneID:   4602746
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0491
- NMPDR:   fig|326297.7.peg.462
- eggNOG:   COG0152
- HOGENOM:   HBG555040
- OMA:   SSRIWDG
- PhylomeDB:   A1S2U5
- ProtClustDB:   PRK13960
- HAMAP:   MF_00137
- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636
- InterPro:   IPR018236
- Gene3D:   G3DSA:3.30.470.20
- PANTHER:   PTHR11609
- TIGRFAMs:   TIGR02735

Pfam domain/function: PF01259 SAICAR_synt

EC number: =6.3.2.6

Molecular weight: Translated: 41013; Mature: 40882

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS01057 SAICAR_SYNTHETASE_1; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLADSVLAVNNDLPIRTDKPVHSGKVRSVYWLTEADSARLIRERGYDVPADTPLAIMVI
CCCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIFHGEGDLRGIPGKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQ
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCEEEECCCCEEEEEE
KARPIKVEAIIRQYITGSMWRAYQKGERVFCGITLPEGLQKDQKLPELLITPSTKGILTG
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCEEECCCCCCEEEC
IPGVPEQDDVNISRADIEANFEAFGFEKKEDIDLYEKLLKEGFGVISEALAKLDQVFVDT
CCCCCCCCCCCEEEECEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVTDSNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKIVENSKEGFRQFLLNHFPDP
CEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCC
DILLNKDRMPEREALARDNALPLDAMMNVSRTYTGIAEKVTGRKIELSDNPKAEIIAILK
CEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
EQYALVD
HHHHCCC
>Mature Secondary Structure 
SLADSVLAVNNDLPIRTDKPVHSGKVRSVYWLTEADSARLIRERGYDVPADTPLAIMVI
CCCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCEEEEEE
SDRISAFDCIFHGEGDLRGIPGKGAALNAISNHWFGLFKENGLADSHILDIPHPFVWIVQ
ECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHEEEEECCCCCCCEEEECCCCEEEEEE
KARPIKVEAIIRQYITGSMWRAYQKGERVFCGITLPEGLQKDQKLPELLITPSTKGILTG
CCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHCCCCEEECCCCCCEEEC
IPGVPEQDDVNISRADIEANFEAFGFEKKEDIDLYEKLLKEGFGVISEALAKLDQVFVDT
CCCCCCCCCCCEEEECEECCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KFEFGYVTDSNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKIVENSKEGFRQFLLNHFPDP
CEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCC
DILLNKDRMPEREALARDNALPLDAMMNVSRTYTGIAEKVTGRKIELSDNPKAEIIAILK
CEEECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHH
EQYALVD
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA