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The map label for this gene is zntR [H]

Identifier: 119773536

GI number: 119773536

Start: 493097

End: 493630

Strand: Direct

Name: zntR [H]

Synonym: Sama_0396

Alternate gene names: 119773536

Gene position: 493097-493630 (Clockwise)

Preceding gene: 119773532

Following gene: 119773537

Centisome position: 11.45

GC content: 55.62

Gene sequence:

>534_bases
ATGTATCGCATTGGTGAATTGGCGAGCCTCTGTGAGGTGAAAGCCGATACCTTGAGGTTTTACGAAAAGCACGGCTTGCT
GGCGCCCTCGATGCGCAGCGATTCGGGCTATCGGCTTTACAGCCGCGATGATGCCGCCCGGCTCAAGTTTATTCTGCGCG
CCAAGGCGGTGGGCTTCAGCCTGAATGAAATCACCGAGCTCTTGTCTATCGAGCTGAATAAGGCTGAGTGGGCCTGCGCC
GATGTGAAAGGCATGGTGGATGACAAGCTGGCGCAGGTCAGTACCAAAATTGCTGAGCTCACGGTGTTTCGTGATTCCCT
CAAACGCCTGTCGGACGCCTGCTGCGGCGGCCCAGAGAGTGCCGAACATTGTTCCATTCTGGAAGCGCTGGAGACCAATC
ATCAGGTGCGCGCCGAATCCCATGGCGCATTGGCAAAGGCTTCCCAAGAAAAAAACTCCGGCGATAACGTATCCACAGAA
CACTCGCCCGCAGTTAACGCGGTAAAGCCAAAGGGTCATGATTCATGCTGCTGA

Upstream 100 bases:

>100_bases
TATCGTTCTGCGAACGACACGTCAGACAATACAGACCCTTGACCTTGGATTAAACTCCAAGGTTTATACTTGCGCCATTG
TTGGAAATTCGGATTAACAC

Downstream 100 bases:

>100_bases
ACAACTTTCTTCACCTGTTTTTGGAGTCAGCCCCCTGGCTGCTGCTGGGGCTGTTTCTGGCGGGCATGCTGAAAATGTTT
GTGCCCATGGCGTGGATGCA

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MYRIGELASLCEVKADTLRFYEKHGLLAPSMRSDSGYRLYSRDDAARLKFILRAKAVGFSLNEITELLSIELNKAEWACA
DVKGMVDDKLAQVSTKIAELTVFRDSLKRLSDACCGGPESAEHCSILEALETNHQVRAESHGALAKASQEKNSGDNVSTE
HSPAVNAVKPKGHDSCC

Sequences:

>Translated_177_residues
MYRIGELASLCEVKADTLRFYEKHGLLAPSMRSDSGYRLYSRDDAARLKFILRAKAVGFSLNEITELLSIELNKAEWACA
DVKGMVDDKLAQVSTKIAELTVFRDSLKRLSDACCGGPESAEHCSILEALETNHQVRAESHGALAKASQEKNSGDNVSTE
HSPAVNAVKPKGHDSCC
>Mature_177_residues
MYRIGELASLCEVKADTLRFYEKHGLLAPSMRSDSGYRLYSRDDAARLKFILRAKAVGFSLNEITELLSIELNKAEWACA
DVKGMVDDKLAQVSTKIAELTVFRDSLKRLSDACCGGPESAEHCSILEALETNHQVRAESHGALAKASQEKNSGDNVSTE
HSPAVNAVKPKGHDSCC

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=131, Percent_Identity=50.381679389313, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=36.2204724409449, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 19330; Mature: 19330

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELASLCEVKADTLRFYEKHGLLAPSMRSDSGYRLYSRDDAARLKFILRAKAVGFS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
LNEITELLSIELNKAEWACADVKGMVDDKLAQVSTKIAELTVFRDSLKRLSDACCGGPES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALETNHQVRAESHGALAKASQEKNSGDNVSTEHSPAVNAVKPKGHDSCC
HHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYRIGELASLCEVKADTLRFYEKHGLLAPSMRSDSGYRLYSRDDAARLKFILRAKAVGFS
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
LNEITELLSIELNKAEWACADVKGMVDDKLAQVSTKIAELTVFRDSLKRLSDACCGGPES
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALETNHQVRAESHGALAKASQEKNSGDNVSTEHSPAVNAVKPKGHDSCC
HHHHHHHHHHHCCCCCHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]