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The map label for this gene is yaeL [C]

Identifier: 119717427

GI number: 119717427

Start: 3402385

End: 3403746

Strand: Reverse

Name: yaeL [C]

Synonym: Noca_3203

Alternate gene names: 119717427

Gene position: 3403746-3402385 (Counterclockwise)

Preceding gene: 119717428

Following gene: 119717426

Centisome position: 68.27

GC content: 69.24

Gene sequence:

>1362_bases
GTGGAACCGCTCTTCTACCTCCTGGGCGTGGTGATCTTCGTGGTCGCCATCCTGGTCTCGATCGGCCTCCACGAGCTCGG
CCACATGATCCCGGCGAAGCGGTTCGGCGGGAAGGTCACGCAGTACTTCATCGGCTTCGGCCCGACCGTGTGGAGCAAGC
GGGTCGGCGAGACCGAGTGGGGCGTCAAGGCGATCCCGCTGGGCGGCTACGTGAAGATCGTCGGCATGCTCCCGCCCGGC
GCGGAGGAGATCGCCGACGAGGTCACGGTCGACGCGGACGGCAACCAGGTCGTGCGGGTGCGCAAGTCCAACACCGGCAT
GTTCACCCAGCTCATCTCCGACGCCCGCGCGGCGGAGTGGGAGACGATCCGGCCCGAGGACAGCGAACGCCTCTTCTACA
AGATGCCGTGGTGGAAGAAGGTCGTCGTGATGGCGGGCGGGCCGACGGTCAACCTGCTGATCGCGTTCACGATCTTCTGG
GGCATCTTCGGTCTCTACGGCGTGCGCACGGCCGAGCCCGACGCCGGCGCCCCGGTGATCGACGAGGTCTCGCAGTGTGT
GATCCCGTACGCCGAGAGCGGGCGCGAATGCACCGACTCCGACCCGCTCAGCCCGGCGGCCGAGGCGGGCCTGCGGCCCG
GCGACGTGGTCACCACCTTCAACGGCACGGCGATCACCGGCTGGGACCAGCTGCGCAGCGCGATCCGCGGAAACGACGAC
GGCAAGGCGGTCATCGGCTACGAGCGCGACGGCCAGTCGATGACCGGCACCACGAGCACCACCGTCGAGGCGCGCCCGAC
CTCCGCGACCGACGAGACCCTGCACCAGGTCGGCTTCCTCGGCGTCACCCCGACCACCCACGAGGTGACCACCACGGGCG
GCCCGATCTACACCCTCGACCAGATGGGTGAGATGACCGTGGTCACGGTCAAGGCGCTCGGCACGCTCCCGGTCAAGGTG
TGGGGCGTGGCGAAGGCGATCGTGGGTGTGGAGGAACGCTCCATCGACAGCCCGGTGAGCATCGTCGGCGGCGGCCGGAT
CGCCGGCGAGACCGTGTCCCACCAGGACTTCCCGGTGGCCGAGAAGGCCGTCTACCTGCTCTCGCTGATCGCGGGGTTCA
ACTTCTTCATCGGGATGTTCAACTTCATCCCGCTGCTGCCGCTCGACGGGGGCCACATCGCGGGCGCGCTCTGGGAGGCC
GTCCGTCGTGGGTTCGCCCGGCTCCGCGGCCGGCCCGACCCCGGCTACGTCGACGTGGCCAAGCTGCTCCCGATCGCGTA
CGGCGTCGCCGCGGTGCTGCTCGTCATGGGCGTGGTGCTGATCGTCGGGGACCTCGTCGTACCCCTGCACCTCGTTTCCT
AG

Upstream 100 bases:

>100_bases
ACCCTCGGAGGTGACGATCGAGGACATCCTCGCCGCCGACGCCTGGGCCCGCGAGGCCACCCGCACCCGCCTCCGGCCCG
ACCAGATCGAGGACTGACCA

Downstream 100 bases:

>100_bases
GTTCCGGTCCTAACATCGAAGCCATGAGCACCCCCGCGTCCGCCGTCAGCCTCGGCCTGCCCGAAGCGCCCCCGCCGGTG
CTCGCGCCGCGCCGCAAGAC

Product: peptidase M50

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEPLFYLLGVVIFVVAILVSIGLHELGHMIPAKRFGGKVTQYFIGFGPTVWSKRVGETEWGVKAIPLGGYVKIVGMLPPG
AEEIADEVTVDADGNQVVRVRKSNTGMFTQLISDARAAEWETIRPEDSERLFYKMPWWKKVVVMAGGPTVNLLIAFTIFW
GIFGLYGVRTAEPDAGAPVIDEVSQCVIPYAESGRECTDSDPLSPAAEAGLRPGDVVTTFNGTAITGWDQLRSAIRGNDD
GKAVIGYERDGQSMTGTTSTTVEARPTSATDETLHQVGFLGVTPTTHEVTTTGGPIYTLDQMGEMTVVTVKALGTLPVKV
WGVAKAIVGVEERSIDSPVSIVGGGRIAGETVSHQDFPVAEKAVYLLSLIAGFNFFIGMFNFIPLLPLDGGHIAGALWEA
VRRGFARLRGRPDPGYVDVAKLLPIAYGVAAVLLVMGVVLIVGDLVVPLHLVS

Sequences:

>Translated_453_residues
MEPLFYLLGVVIFVVAILVSIGLHELGHMIPAKRFGGKVTQYFIGFGPTVWSKRVGETEWGVKAIPLGGYVKIVGMLPPG
AEEIADEVTVDADGNQVVRVRKSNTGMFTQLISDARAAEWETIRPEDSERLFYKMPWWKKVVVMAGGPTVNLLIAFTIFW
GIFGLYGVRTAEPDAGAPVIDEVSQCVIPYAESGRECTDSDPLSPAAEAGLRPGDVVTTFNGTAITGWDQLRSAIRGNDD
GKAVIGYERDGQSMTGTTSTTVEARPTSATDETLHQVGFLGVTPTTHEVTTTGGPIYTLDQMGEMTVVTVKALGTLPVKV
WGVAKAIVGVEERSIDSPVSIVGGGRIAGETVSHQDFPVAEKAVYLLSLIAGFNFFIGMFNFIPLLPLDGGHIAGALWEA
VRRGFARLRGRPDPGYVDVAKLLPIAYGVAAVLLVMGVVLIVGDLVVPLHLVS
>Mature_453_residues
MEPLFYLLGVVIFVVAILVSIGLHELGHMIPAKRFGGKVTQYFIGFGPTVWSKRVGETEWGVKAIPLGGYVKIVGMLPPG
AEEIADEVTVDADGNQVVRVRKSNTGMFTQLISDARAAEWETIRPEDSERLFYKMPWWKKVVVMAGGPTVNLLIAFTIFW
GIFGLYGVRTAEPDAGAPVIDEVSQCVIPYAESGRECTDSDPLSPAAEAGLRPGDVVTTFNGTAITGWDQLRSAIRGNDD
GKAVIGYERDGQSMTGTTSTTVEARPTSATDETLHQVGFLGVTPTTHEVTTTGGPIYTLDQMGEMTVVTVKALGTLPVKV
WGVAKAIVGVEERSIDSPVSIVGGGRIAGETVSHQDFPVAEKAVYLLSLIAGFNFFIGMFNFIPLLPLDGGHIAGALWEA
VRRGFARLRGRPDPGYVDVAKLLPIAYGVAAVLLVMGVVLIVGDLVVPLHLVS

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=486, Percent_Identity=23.0452674897119, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR008915 [H]

Pfam domain/function: PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 48455; Mature: 48455

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLFYLLGVVIFVVAILVSIGLHELGHMIPAKRFGGKVTQYFIGFGPTVWSKRVGETEW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHEEHHEECCCHHHHHCCCCCCC
GVKAIPLGGYVKIVGMLPPGAEEIADEVTVDADGNQVVRVRKSNTGMFTQLISDARAAEW
CEEEEECCCEEEEEEECCCCHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCC
ETIRPEDSERLFYKMPWWKKVVVMAGGPTVNLLIAFTIFWGIFGLYGVRTAEPDAGAPVI
CCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DEVSQCVIPYAESGRECTDSDPLSPAAEAGLRPGDVVTTFNGTAITGWDQLRSAIRGNDD
HHHHHHCCCHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEEECHHHHHHHHCCCCC
GKAVIGYERDGQSMTGTTSTTVEARPTSATDETLHQVGFLGVTPTTHEVTTTGGPIYTLD
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHCCEECCCCCCEEECCCCCEEECC
QMGEMTVVTVKALGTLPVKVWGVAKAIVGVEERSIDSPVSIVGGGRIAGETVSHQDFPVA
CCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHCCCCCEEEEECCEECCCCCCCCCCCHH
EKAVYLLSLIAGFNFFIGMFNFIPLLPLDGGHIAGALWEAVRRGFARLRGRPDPGYVDVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KLLPIAYGVAAVLLVMGVVLIVGDLVVPLHLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MEPLFYLLGVVIFVVAILVSIGLHELGHMIPAKRFGGKVTQYFIGFGPTVWSKRVGETEW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHEEHHEECCCHHHHHCCCCCCC
GVKAIPLGGYVKIVGMLPPGAEEIADEVTVDADGNQVVRVRKSNTGMFTQLISDARAAEW
CEEEEECCCEEEEEEECCCCHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHHHHHCCC
ETIRPEDSERLFYKMPWWKKVVVMAGGPTVNLLIAFTIFWGIFGLYGVRTAEPDAGAPVI
CCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
DEVSQCVIPYAESGRECTDSDPLSPAAEAGLRPGDVVTTFNGTAITGWDQLRSAIRGNDD
HHHHHHCCCHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCEEECHHHHHHHHCCCCC
GKAVIGYERDGQSMTGTTSTTVEARPTSATDETLHQVGFLGVTPTTHEVTTTGGPIYTLD
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHCCEECCCCCCEEECCCCCEEECC
QMGEMTVVTVKALGTLPVKVWGVAKAIVGVEERSIDSPVSIVGGGRIAGETVSHQDFPVA
CCCCEEEEEEEECCCCCCHHHHHHHHHHCCHHHCCCCCEEEEECCEECCCCCCCCCCCHH
EKAVYLLSLIAGFNFFIGMFNFIPLLPLDGGHIAGALWEAVRRGFARLRGRPDPGYVDVA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
KLLPIAYGVAAVLLVMGVVLIVGDLVVPLHLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]