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The map label for this gene is dxr [H]

Identifier: 119717428

GI number: 119717428

Start: 3403750

End: 3404868

Strand: Reverse

Name: dxr [H]

Synonym: Noca_3204

Alternate gene names: 119717428

Gene position: 3404868-3403750 (Counterclockwise)

Preceding gene: 119717430

Following gene: 119717427

Centisome position: 68.29

GC content: 73.28

Gene sequence:

>1119_bases
GTGAGCAGGCCGGTCAGAGACGTCGCGATCCTCGGCAGCACCGGGTCGATCGGCACCCAGGCGCTCGATCTCGTGCGGGC
CAACCCGGACCGGTTCCGGGTCGTGGCGTTGACCGCCGGCGGCTCGAGCCCCGAGCTGTTCGAGCGCCAGGTGGCCGAGT
TCGCCCCGGCGTACCCCGACCTCTTCTCCGGGCTGGGCGAGGAGGCCTCGGTCGAGGCGGCCACCCGGCCGTGCGACGTC
GTCCTCAACGGCATCACCGGCGCGGTCGGGCTGCGCCCGACCCTGGCCGCCCTCGACGCCGGGCACACGCTCGCGTTGGC
CAACAAGGAGTCGCTGATCATGGGTGGCCCCCTGGTGCTCGAGCGTGCGAAGCCGGGCCAGATCGTGCCGGTCGACTCCG
AGCACAGCGCGATCGCCCAGTGCCTGCGTGGCGGCCGTGCCGACGAGGTACGCCGGCTGGTGCTGACCGCGAGCGGCGGC
CCGTTCCGCGGCCGCACCCGCGAGGAGCTGGCCGACGTGACGCCCGCGCAGGCCATGGCGCACCCGACCTGGGACATGGG
CCCGGTGATCACCATCAACTCGGCGACCCTGGTCAACAAGGGGTTGGAGGTGATCGAGGCGCACCTGCTGTTCGGCATCC
CCTTCGACCGGATCGAGGTCGTGGTGCACCCGACCAGCGTCGTGCACTCGATGGTCGAGTTCGTCGACGGCTCGACGCTG
GTGCAGGCCAGCCCGCCGACCATGCTGATCCCGATCGCGCTCGGCCTGTCCTGGCCGGACCGGGTGCCGGACGCCGCGCC
CCCGGTCGACTGGAGCCGGCCGGAGACCTGGGAGTTCTTCCCGCTCGACGACGCGGCGTTCCCGGCCGTGGCGCTGGCCC
GCGAGGCGGGGCAGCGCGGCGGGACCGCCCCGGCGGTCTACAACGCCGCCAACGAGGTCGCCGTCGACGCCTTCCGCACG
GGCGCGCTGGCGTTCACCGAGATCGTGCCCACGGTTCAGGCCGTTCTCAGCCGGCACGACGTACCCTCGGAGGTGACGAT
CGAGGACATCCTCGCCGCCGACGCCTGGGCCCGCGAGGCCACCCGCACCCGCCTCCGGCCCGACCAGATCGAGGACTGA

Upstream 100 bases:

>100_bases
GTCCGACGGGATCCGTCTCGGGGAGGGGGTCAGGGCGACGATTTCGAAGGCTGGTGCCCCGGATTCCGTCGCGCGGTCCC
CGCTGCGGGAGACTGGACGC

Downstream 100 bases:

>100_bases
CCAGTGGAACCGCTCTTCTACCTCCTGGGCGTGGTGATCTTCGTGGTCGCCATCCTGGTCTCGATCGGCCTCCACGAGCT
CGGCCACATGATCCCGGCGA

Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Products: NA

Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSRPVRDVAILGSTGSIGTQALDLVRANPDRFRVVALTAGGSSPELFERQVAEFAPAYPDLFSGLGEEASVEAATRPCDV
VLNGITGAVGLRPTLAALDAGHTLALANKESLIMGGPLVLERAKPGQIVPVDSEHSAIAQCLRGGRADEVRRLVLTASGG
PFRGRTREELADVTPAQAMAHPTWDMGPVITINSATLVNKGLEVIEAHLLFGIPFDRIEVVVHPTSVVHSMVEFVDGSTL
VQASPPTMLIPIALGLSWPDRVPDAAPPVDWSRPETWEFFPLDDAAFPAVALAREAGQRGGTAPAVYNAANEVAVDAFRT
GALAFTEIVPTVQAVLSRHDVPSEVTIEDILAADAWAREATRTRLRPDQIED

Sequences:

>Translated_372_residues
MSRPVRDVAILGSTGSIGTQALDLVRANPDRFRVVALTAGGSSPELFERQVAEFAPAYPDLFSGLGEEASVEAATRPCDV
VLNGITGAVGLRPTLAALDAGHTLALANKESLIMGGPLVLERAKPGQIVPVDSEHSAIAQCLRGGRADEVRRLVLTASGG
PFRGRTREELADVTPAQAMAHPTWDMGPVITINSATLVNKGLEVIEAHLLFGIPFDRIEVVVHPTSVVHSMVEFVDGSTL
VQASPPTMLIPIALGLSWPDRVPDAAPPVDWSRPETWEFFPLDDAAFPAVALAREAGQRGGTAPAVYNAANEVAVDAFRT
GALAFTEIVPTVQAVLSRHDVPSEVTIEDILAADAWAREATRTRLRPDQIED
>Mature_371_residues
SRPVRDVAILGSTGSIGTQALDLVRANPDRFRVVALTAGGSSPELFERQVAEFAPAYPDLFSGLGEEASVEAATRPCDVV
LNGITGAVGLRPTLAALDAGHTLALANKESLIMGGPLVLERAKPGQIVPVDSEHSAIAQCLRGGRADEVRRLVLTASGGP
FRGRTREELADVTPAQAMAHPTWDMGPVITINSATLVNKGLEVIEAHLLFGIPFDRIEVVVHPTSVVHSMVEFVDGSTLV
QASPPTMLIPIALGLSWPDRVPDAAPPVDWSRPETWEFFPLDDAAFPAVALAREAGQRGGTAPAVYNAANEVAVDAFRTG
ALAFTEIVPTVQAVLSRHDVPSEVTIEDILAADAWAREATRTRLRPDQIED

Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) [H]

COG id: COG0743

COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DXR family [H]

Homologues:

Organism=Escherichia coli, GI1786369, Length=391, Percent_Identity=41.9437340153453, Blast_Score=265, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003821
- InterPro:   IPR013644
- InterPro:   IPR013512
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom [H]

EC number: =1.1.1.267 [H]

Molecular weight: Translated: 39484; Mature: 39353

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPVRDVAILGSTGSIGTQALDLVRANPDRFRVVALTAGGSSPELFERQVAEFAPAYPD
CCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHH
LFSGLGEEASVEAATRPCDVVLNGITGAVGLRPTLAALDAGHTLALANKESLIMGGPLVL
HHHCCCCCCCHHHCCCCHHHEEECCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCCEEE
ERAKPGQIVPVDSEHSAIAQCLRGGRADEVRRLVLTASGGPFRGRTREELADVTPAQAMA
ECCCCCCEEECCCCHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCHHHHHHCCHHHHHC
HPTWDMGPVITINSATLVNKGLEVIEAHLLFGIPFDRIEVVVHPTSVVHSMVEFVDGSTL
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCEE
VQASPPTMLIPIALGLSWPDRVPDAAPPVDWSRPETWEFFPLDDAAFPAVALAREAGQRG
EECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
GTAPAVYNAANEVAVDAFRTGALAFTEIVPTVQAVLSRHDVPSEVTIEDILAADAWAREA
CCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TRTRLRPDQIED
HHHCCCCCCCCC
>Mature Secondary Structure 
SRPVRDVAILGSTGSIGTQALDLVRANPDRFRVVALTAGGSSPELFERQVAEFAPAYPD
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCHH
LFSGLGEEASVEAATRPCDVVLNGITGAVGLRPTLAALDAGHTLALANKESLIMGGPLVL
HHHCCCCCCCHHHCCCCHHHEEECCCCCCCCCHHHHHHCCCCEEEEECCCCEEECCCEEE
ERAKPGQIVPVDSEHSAIAQCLRGGRADEVRRLVLTASGGPFRGRTREELADVTPAQAMA
ECCCCCCEEECCCCHHHHHHHHHCCCHHHEEEEEEEECCCCCCCCCHHHHHHCCHHHHHC
HPTWDMGPVITINSATLVNKGLEVIEAHLLFGIPFDRIEVVVHPTSVVHSMVEFVDGSTL
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCEE
VQASPPTMLIPIALGLSWPDRVPDAAPPVDWSRPETWEFFPLDDAAFPAVALAREAGQRG
EECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCC
GTAPAVYNAANEVAVDAFRTGALAFTEIVPTVQAVLSRHDVPSEVTIEDILAADAWAREA
CCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
TRTRLRPDQIED
HHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA