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The map label for this gene is ispG [H]

Identifier: 119717426

GI number: 119717426

Start: 3401198

End: 3402361

Strand: Reverse

Name: ispG [H]

Synonym: Noca_3202

Alternate gene names: 119717426

Gene position: 3402361-3401198 (Counterclockwise)

Preceding gene: 119717427

Following gene: 119717425

Centisome position: 68.24

GC content: 70.27

Gene sequence:

>1164_bases
ATGAGCACCCCCGCGTCCGCCGTCAGCCTCGGCCTGCCCGAAGCGCCCCCGCCGGTGCTCGCGCCGCGCCGCAAGACCCG
CCAGATCCGGGTCGGCAAGGTCGGCGTCGGCAGCGACTACCCGGTCTCGGTCCAGTCGATGACGACCACGCAGACCTCGG
ACGTCAACAGCACCCTGCAGCAGATCGCCGAGCTCACCGCGACCGGGTGCGACATCGTCCGGGTGGCGTGCCCCAGCCAG
GACGACGCCGACGCGCTGCCGGCGATCGCGCAGAAGTCGCAGATCCCGGTGATCGCCGACATCCACTTCCAGCCGAAGTA
CGTGTTCGCCGCGATCGACGCCGGCTGCGCGGCGGTCCGCGTCAACCCCGGCAACATCCGCAAGTTCGACGACCAGGTCA
AGGAGATCGCCCGCGCGGCCAAGGACCGCGGCACCTCCATCCGGATCGGCGTCAACGCCGGCTCCCTGGACAAGCGGCTG
CTCGAGAAGTACGGCAAGGCCACGCCCGAGGCGCTGGTCGAGTCCGCGGTGTGGGAGGCCAGCCTGTTCGAGGAGCACGA
CTTCCACGACTTCAAGATCTCGGTCAAGCACAACGACCCCGTCGTGATGGTGCGCGCCTACGAGATGCTCGCCGAGCGCG
GGGACTGGCCGCTCCACCTCGGCGTCACCGAGGCGGGGCCGGCGTTCCAGGGCACGATCAAGTCGGCCACGGCCTTCGGC
GCCCTTCTCTCGCAGGGCATCGGCGACACGATCCGGGTCTCGCTGTCCGCGCCGCCGGTCGAGGAGGTCAAGGTCGGCAT
CCAGATCCTCCAGTCGCTCAACCTCCGGCCCCGCAAGCTCGAGATCGTGTCCTGCCCGTCCTGCGGTCGCGCCCAGGTCG
ACGTCTACACGCTGGCCGAGCAGGTGACTGCCGGCCTCGAGGGGCTCGAGGTGCCGTTGCGGGTGGCCGTCATGGGCTGC
GTCGTCAACGGACCGGGGGAGGCCCGCGAGGCCGACCTCGGCGTCGCCTCCGGCAACGGGAAGGGCCAGATCTTCGTCAG
GGGCGAGGTCATCAAGACCGTGCCGGAGTCGAAGATCGTGGAGACCCTGATCGAGGAGGCCATGCGGATCGCGGAGGGCA
TGGAGTCGGTGGACGGCGCCGGCGCCTCGGTCACCGTCAGCTGA

Upstream 100 bases:

>100_bases
TCGCCGCGGTGCTGCTCGTCATGGGCGTGGTGCTGATCGTCGGGGACCTCGTCGTACCCCTGCACCTCGTTTCCTAGGTT
CCGGTCCTAACATCGAAGCC

Downstream 100 bases:

>100_bases
ACGGCCGGAGAACACCGCCGCTCGGGTGGTGACGCGGAGGCCCGTCGCACCGCACACTGCGGCTGTGAGGATCTCCCGCA
GGCAGCTCATCGGTGCGGCA

Product: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase

Products: NA

Alternate protein names: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSTPASAVSLGLPEAPPPVLAPRRKTRQIRVGKVGVGSDYPVSVQSMTTTQTSDVNSTLQQIAELTATGCDIVRVACPSQ
DDADALPAIAQKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIRKFDDQVKEIARAAKDRGTSIRIGVNAGSLDKRL
LEKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPVVMVRAYEMLAERGDWPLHLGVTEAGPAFQGTIKSATAFG
ALLSQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGLEGLEVPLRVAVMGC
VVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESKIVETLIEEAMRIAEGMESVDGAGASVTVS

Sequences:

>Translated_387_residues
MSTPASAVSLGLPEAPPPVLAPRRKTRQIRVGKVGVGSDYPVSVQSMTTTQTSDVNSTLQQIAELTATGCDIVRVACPSQ
DDADALPAIAQKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIRKFDDQVKEIARAAKDRGTSIRIGVNAGSLDKRL
LEKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPVVMVRAYEMLAERGDWPLHLGVTEAGPAFQGTIKSATAFG
ALLSQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGLEGLEVPLRVAVMGC
VVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESKIVETLIEEAMRIAEGMESVDGAGASVTVS
>Mature_386_residues
STPASAVSLGLPEAPPPVLAPRRKTRQIRVGKVGVGSDYPVSVQSMTTTQTSDVNSTLQQIAELTATGCDIVRVACPSQD
DADALPAIAQKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIRKFDDQVKEIARAAKDRGTSIRIGVNAGSLDKRLL
EKYGKATPEALVESAVWEASLFEEHDFHDFKISVKHNDPVVMVRAYEMLAERGDWPLHLGVTEAGPAFQGTIKSATAFGA
LLSQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAEQVTAGLEGLEVPLRVAVMGCV
VNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESKIVETLIEEAMRIAEGMESVDGAGASVTVS

Specific function: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate [H]

COG id: COG0821

COG function: function code I; Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispG family [H]

Homologues:

Organism=Escherichia coli, GI1788863, Length=326, Percent_Identity=46.6257668711656, Blast_Score=307, Evalue=6e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011005
- InterPro:   IPR016425
- InterPro:   IPR004588 [H]

Pfam domain/function: PF04551 GcpE [H]

EC number: =1.17.7.1 [H]

Molecular weight: Translated: 40970; Mature: 40839

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPASAVSLGLPEAPPPVLAPRRKTRQIRVGKVGVGSDYPVSVQSMTTTQTSDVNSTLQ
CCCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHH
QIAELTATGCDIVRVACPSQDDADALPAIAQKSQIPVIADIHFQPKYVFAAIDAGCAAVR
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEEEE
VNPGNIRKFDDQVKEIARAAKDRGTSIRIGVNAGSLDKRLLEKYGKATPEALVESAVWEA
ECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SLFEEHDFHDFKISVKHNDPVVMVRAYEMLAERGDWPLHLGVTEAGPAFQGTIKSATAFG
HHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
ALLSQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAE
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHH
QVTAGLEGLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESKIV
HHHHCCCCCCCHHEEEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECHHEECCCHHHHH
ETLIEEAMRIAEGMESVDGAGASVTVS
HHHHHHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure 
STPASAVSLGLPEAPPPVLAPRRKTRQIRVGKVGVGSDYPVSVQSMTTTQTSDVNSTLQ
CCCCCHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCHHHHHHHH
QIAELTATGCDIVRVACPSQDDADALPAIAQKSQIPVIADIHFQPKYVFAAIDAGCAAVR
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEEEE
VNPGNIRKFDDQVKEIARAAKDRGTSIRIGVNAGSLDKRLLEKYGKATPEALVESAVWEA
ECCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHH
SLFEEHDFHDFKISVKHNDPVVMVRAYEMLAERGDWPLHLGVTEAGPAFQGTIKSATAFG
HHHCCCCCCEEEEEEECCCCEEEEEHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
ALLSQGIGDTIRVSLSAPPVEEVKVGIQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLAE
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEHHHHHHH
QVTAGLEGLEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPESKIV
HHHHCCCCCCCHHEEEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECHHEECCCHHHHH
ETLIEEAMRIAEGMESVDGAGASVTVS
HHHHHHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA