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The map label for this gene is mraY

Identifier: 119717290

GI number: 119717290

Start: 3264289

End: 3265383

Strand: Reverse

Name: mraY

Synonym: Noca_3066

Alternate gene names: 119717290

Gene position: 3265383-3264289 (Counterclockwise)

Preceding gene: 119717291

Following gene: 119717289

Centisome position: 65.49

GC content: 67.76

Gene sequence:

>1095_bases
ATGAGAGCCATCCTGTTCGGAGGCGGTCTGGCCCTGCTCGTCTCGCTGCTCGGCACCCGGGTCGCGATCAACCAGTTCAC
GCGGCTGGGCTACGGCCAGGAGATCCGCGACGACGGCCCGACCAGCCACCACACCAAGCGCGGCACGCCGACGATGGGCG
GCGTCGTCATCATCCTCGCGACCGTGGTCGGCTACTTCGGCGCGAAGCTGATCACCGGCGACATGCCGACCGCCTCGGCG
CTGCTCCTGCTGTTCCTGCTCGTCGGGACCGGCCTGGTCGGCTTCGTCGACGACTTCATCAAGATCTCCAAGCAGCGCAG
CCTCGGGCTGCGGAGCAAGGCGAAGATGATCGGGCTCACCGTGGTGGCCCTGGTCTTCGGGATCCTGTCGCTGTCGTCGT
GGCTCGAGGACGACCGCGGGCAGTCGCCGGCGTCCCGGCACATCTCCTTCATCCGTGACATCGGCTGGATCACGCTGCCG
ACCGTCGTCGTCCTGCTGCTGATCTGGCTGATCATCGCGGCCACGTCCAACGGCGTGAACCTCACCGACGGGCTCGACGG
GCTCGCCACGGGCGCCAGCGTGATGGTCTTCGGCGCCTACATGTTCGTGAACATCTGGCAGAACAACCAGTGGTGCGGCC
AGACCGGCCTCGACCAGCCGAACCTGTGCTACGAGGTCCGCGATCCGCTCGACCTGGCGGTCGTGGCCGCCGCGATCACC
GGCGCGTGCTTCGGCTTCCTGTGGTGGAACGCGTCACCCGCCGCGATCTTCATGGGCGACACCGGGTCCCTGGCCCTCGG
CGGTGCGCTCGCCGGCCTGGCCATCCTCACCCGCACCGAGCTGCTCCTGATCATCCTCGGCGGGCTGTTCGTGATGGAGA
CGGTGTCGGTGATGCTGCAGGTCGCCACGTTCAAGGCCACCAAGCGACTGACCGGCACCGGGCGGCGGCTGTTCCGCATC
GCGCCGATCCACCACCACTTCGAGATGCTCGGGTGGGAGCAGGTGACCGTGGTGATCCGGTTCTGGATCATCACCGGGAT
CTGTGTCGCCGCGGGCCTGGGCGTGTTCTACGCGGAATGGGTCGCCGGCATCTGA

Upstream 100 bases:

>100_bases
CCGGTGACGTGGTCCTGGTCAAGGCGTCGCACGGCGTCGCCTTGTGGGAGGTCGCGGACGCACTGCTCGACACCGACCCG
GAGGGAGACCGAACCGAGCC

Downstream 100 bases:

>100_bases
TGGATCTCGATCACCTCGGTCGTCACGACTCCTGGGAAGGGGTCCGCGCCGTCGTCGCCGGCTTCGGCGTCTCCGGCTTC
GCGGCCGCCGACAACCTCAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRAILFGGGLALLVSLLGTRVAINQFTRLGYGQEIRDDGPTSHHTKRGTPTMGGVVIILATVVGYFGAKLITGDMPTASA
LLLLFLLVGTGLVGFVDDFIKISKQRSLGLRSKAKMIGLTVVALVFGILSLSSWLEDDRGQSPASRHISFIRDIGWITLP
TVVVLLLIWLIIAATSNGVNLTDGLDGLATGASVMVFGAYMFVNIWQNNQWCGQTGLDQPNLCYEVRDPLDLAVVAAAIT
GACFGFLWWNASPAAIFMGDTGSLALGGALAGLAILTRTELLLIILGGLFVMETVSVMLQVATFKATKRLTGTGRRLFRI
APIHHHFEMLGWEQVTVVIRFWIITGICVAAGLGVFYAEWVAGI

Sequences:

>Translated_364_residues
MRAILFGGGLALLVSLLGTRVAINQFTRLGYGQEIRDDGPTSHHTKRGTPTMGGVVIILATVVGYFGAKLITGDMPTASA
LLLLFLLVGTGLVGFVDDFIKISKQRSLGLRSKAKMIGLTVVALVFGILSLSSWLEDDRGQSPASRHISFIRDIGWITLP
TVVVLLLIWLIIAATSNGVNLTDGLDGLATGASVMVFGAYMFVNIWQNNQWCGQTGLDQPNLCYEVRDPLDLAVVAAAIT
GACFGFLWWNASPAAIFMGDTGSLALGGALAGLAILTRTELLLIILGGLFVMETVSVMLQVATFKATKRLTGTGRRLFRI
APIHHHFEMLGWEQVTVVIRFWIITGICVAAGLGVFYAEWVAGI
>Mature_364_residues
MRAILFGGGLALLVSLLGTRVAINQFTRLGYGQEIRDDGPTSHHTKRGTPTMGGVVIILATVVGYFGAKLITGDMPTASA
LLLLFLLVGTGLVGFVDDFIKISKQRSLGLRSKAKMIGLTVVALVFGILSLSSWLEDDRGQSPASRHISFIRDIGWITLP
TVVVLLLIWLIIAATSNGVNLTDGLDGLATGASVMVFGAYMFVNIWQNNQWCGQTGLDQPNLCYEVRDPLDLAVVAAAIT
GACFGFLWWNASPAAIFMGDTGSLALGGALAGLAILTRTELLLIILGGLFVMETVSVMLQVATFKATKRLTGTGRRLFRI
APIHHHFEMLGWEQVTVVIRFWIITGICVAAGLGVFYAEWVAGI

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=348, Percent_Identity=41.9540229885057, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_NOCSJ (A1SL83)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924255.1
- STRING:   A1SL83
- GeneID:   4600183
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3066
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- PhylomeDB:   A1SL83
- ProtClustDB:   PRK00108
- BioCyc:   NSP35761:NOCA_3066-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39010; Mature: 39010

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x19434274)-; HASH(0x1a54fae8)-; HASH(0x1a0e8280)-; HASH(0x197d90c4)-; HASH(0x1945ba18)-; HASH(0x19897804)-; HASH(0x199ff34c)-; HASH(0x1a56caa0)-; HASH(0x19dc03ec)-; HASH(0x1a54bfe4)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAILFGGGLALLVSLLGTRVAINQFTRLGYGQEIRDDGPTSHHTKRGTPTMGGVVIILA
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TVVGYFGAKLITGDMPTASALLLLFLLVGTGLVGFVDDFIKISKQRSLGLRSKAKMIGLT
HHHHHHCCEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVALVFGILSLSSWLEDDRGQSPASRHISFIRDIGWITLPTVVVLLLIWLIIAATSNGVN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
LTDGLDGLATGASVMVFGAYMFVNIWQNNQWCGQTGLDQPNLCYEVRDPLDLAVVAAAIT
CCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
GACFGFLWWNASPAAIFMGDTGSLALGGALAGLAILTRTELLLIILGGLFVMETVSVMLQ
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATFKATKRLTGTGRRLFRIAPIHHHFEMLGWEQVTVVIRFWIITGICVAAGLGVFYAEW
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGI
HHCH
>Mature Secondary Structure
MRAILFGGGLALLVSLLGTRVAINQFTRLGYGQEIRDDGPTSHHTKRGTPTMGGVVIILA
CCEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TVVGYFGAKLITGDMPTASALLLLFLLVGTGLVGFVDDFIKISKQRSLGLRSKAKMIGLT
HHHHHHCCEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
VVALVFGILSLSSWLEDDRGQSPASRHISFIRDIGWITLPTVVVLLLIWLIIAATSNGVN
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
LTDGLDGLATGASVMVFGAYMFVNIWQNNQWCGQTGLDQPNLCYEVRDPLDLAVVAAAIT
CCCCCCHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
GACFGFLWWNASPAAIFMGDTGSLALGGALAGLAILTRTELLLIILGGLFVMETVSVMLQ
HHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VATFKATKRLTGTGRRLFRIAPIHHHFEMLGWEQVTVVIRFWIITGICVAAGLGVFYAEW
HHHHHHHHHHCCCCCEEEEECCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGI
HHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA