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The map label for this gene is ftsW [C]

Identifier: 119717288

GI number: 119717288

Start: 3261527

End: 3262780

Strand: Reverse

Name: ftsW [C]

Synonym: Noca_3064

Alternate gene names: 119717288

Gene position: 3262780-3261527 (Counterclockwise)

Preceding gene: 119717289

Following gene: 119717287

Centisome position: 65.44

GC content: 71.29

Gene sequence:

>1254_bases
ATGACGACCGCGAACCCCCTGGACCCCGTCGAGCGGGCGCGGCCGGTCGGCCGGCGCTCGGTGGGTGGCTGGTACGCCGC
CGTCCGGCATGCGCTGGACCGCCCGCTGACCGCCTACTACCTGCTGCTCGGCGCGTCCGCGCTGCTGCTGACCATCGGGC
TGATCATGGTCCTCAGCGCCTCGAGCGTGTACTCCTACGAGAAGAACGGCAGCTCCTACGCCGTCGTCGAGCGCCAGCTG
CTCTGGGTGCTGATCGGCATCCCGTGCGCCTGGATCGCCTCCCGGTTGCCGCACTCCGTCCTGCGCCGGTTCGCCTGGCT
GGCGCTGATCGTGTCGATCGTGCTGCTCGCGCTGACCCAGCTGGGCCTGGGCCGCACCGTCAACGGCAACACCAACTGGC
TCGGGGTCGGGCCGTTCGTGGTCCAGCCCGCGGAGATCGCGAAGCTCTCGATCGTGCTGTGGGCGGCGCACGTGTACGCG
CTGAAGGAGAAGCGGCTGCGGAGCCTGCACGAGGTCTTCGTGCCGGTGGTGCCCGGCATGCTCGTGGTGGTCGGCCTGGT
CGTCCTCGGCCACGACCTCGGCACCGCGCTGGTGCTGATGGCGATCCTGCTCGCGATGCTGTGGGTGGTGGGCGCGCCCG
GCCGCCTGTTCTCCGTCTCGCTGACCGTGATCGGCGTCGTCGCCATCTGGCTGGCCTCGACCAGCCCCGAGCGGCGCGAG
CGGCTGACGAACTTCGCCGACCCGTTCAAGGACTTCCACAACGCCGGCTGGCAGCCCGCCCACGGCCTGTACGCGCTCTC
GCACGGCGGCGTGTTCGGGCAGGGCCTCGGCGCCAGCCAGCAGAAGTGGGGCAACCTGCCCGAGGCACACACCGACTTCA
TCTTCGCGGTGCTCGGCGAGGAGCTCGGCCTGGTCGGCACCCTGCTGGTGATCGCGCTGTTCCTCACGATCGCGTACGCC
GCGATCCGGGTCGCCGCGCACACGCAGGACGCGTTCGTGCGCTACACGACGTTCGGCATCGTCGTGTGGCTGCTCGGCCA
GATGATCATCAACGTCGGCATGGTGCTCGCGCTGCTGCCGGTCATCGGCATCCCGCTGCCGCTGGTGTCCTACGGCGGCT
CGGCGCTGGTGCCGTCCTTGGTCGCGCTCGGCCTGCTCATCGGGTTCGCGCGCCGCGAGCCGGAGGCCGCCCGCGCCCTG
GCCCAGCGCAAGAAGGCCCGCTCCGCCGGGCTCTCCGCGGGTCGGCTCTCCTAG

Upstream 100 bases:

>100_bases
CACCAACTACGCCGAGCGCGGCGACGCGTTCGCCGACGCCGTACGACGCAGGCTGTAGGCCGACCGCACGCAGACCGGAC
CCGACGGGAGGGGGTGGGGC

Downstream 100 bases:

>100_bases
GCTGGTGCCGATGCGCGTTCTCCTCGCCGGCGGCGGCACCGCCGGCCACACCTCGCCCCTGCTCGCGACCGCCGACGCCC
TGCGCCGCCTCGAGCCCGAC

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTTANPLDPVERARPVGRRSVGGWYAAVRHALDRPLTAYYLLLGASALLLTIGLIMVLSASSVYSYEKNGSSYAVVERQL
LWVLIGIPCAWIASRLPHSVLRRFAWLALIVSIVLLALTQLGLGRTVNGNTNWLGVGPFVVQPAEIAKLSIVLWAAHVYA
LKEKRLRSLHEVFVPVVPGMLVVVGLVVLGHDLGTALVLMAILLAMLWVVGAPGRLFSVSLTVIGVVAIWLASTSPERRE
RLTNFADPFKDFHNAGWQPAHGLYALSHGGVFGQGLGASQQKWGNLPEAHTDFIFAVLGEELGLVGTLLVIALFLTIAYA
AIRVAAHTQDAFVRYTTFGIVVWLLGQMIINVGMVLALLPVIGIPLPLVSYGGSALVPSLVALGLLIGFARREPEAARAL
AQRKKARSAGLSAGRLS

Sequences:

>Translated_417_residues
MTTANPLDPVERARPVGRRSVGGWYAAVRHALDRPLTAYYLLLGASALLLTIGLIMVLSASSVYSYEKNGSSYAVVERQL
LWVLIGIPCAWIASRLPHSVLRRFAWLALIVSIVLLALTQLGLGRTVNGNTNWLGVGPFVVQPAEIAKLSIVLWAAHVYA
LKEKRLRSLHEVFVPVVPGMLVVVGLVVLGHDLGTALVLMAILLAMLWVVGAPGRLFSVSLTVIGVVAIWLASTSPERRE
RLTNFADPFKDFHNAGWQPAHGLYALSHGGVFGQGLGASQQKWGNLPEAHTDFIFAVLGEELGLVGTLLVIALFLTIAYA
AIRVAAHTQDAFVRYTTFGIVVWLLGQMIINVGMVLALLPVIGIPLPLVSYGGSALVPSLVALGLLIGFARREPEAARAL
AQRKKARSAGLSAGRLS
>Mature_416_residues
TTANPLDPVERARPVGRRSVGGWYAAVRHALDRPLTAYYLLLGASALLLTIGLIMVLSASSVYSYEKNGSSYAVVERQLL
WVLIGIPCAWIASRLPHSVLRRFAWLALIVSIVLLALTQLGLGRTVNGNTNWLGVGPFVVQPAEIAKLSIVLWAAHVYAL
KEKRLRSLHEVFVPVVPGMLVVVGLVVLGHDLGTALVLMAILLAMLWVVGAPGRLFSVSLTVIGVVAIWLASTSPERRER
LTNFADPFKDFHNAGWQPAHGLYALSHGGVFGQGLGASQQKWGNLPEAHTDFIFAVLGEELGLVGTLLVIALFLTIAYAA
IRVAAHTQDAFVRYTTFGIVVWLLGQMIINVGMVLALLPVIGIPLPLVSYGGSALVPSLVALGLLIGFARREPEAARALA
QRKKARSAGLSAGRLS

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=373, Percent_Identity=34.0482573726542, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1786853, Length=337, Percent_Identity=31.7507418397626, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44726; Mature: 44594

Theoretical pI: Translated: 10.52; Mature: 10.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANPLDPVERARPVGRRSVGGWYAAVRHALDRPLTAYYLLLGASALLLTIGLIMVLSA
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSVYSYEKNGSSYAVVERQLLWVLIGIPCAWIASRLPHSVLRRFAWLALIVSIVLLALTQ
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGLGRTVNGNTNWLGVGPFVVQPAEIAKLSIVLWAAHVYALKEKRLRSLHEVFVPVVPGM
HCCCCEECCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVVGLVVLGHDLGTALVLMAILLAMLWVVGAPGRLFSVSLTVIGVVAIWLASTSPERRE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RLTNFADPFKDFHNAGWQPAHGLYALSHGGVFGQGLGASQQKWGNLPEAHTDFIFAVLGE
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHH
ELGLVGTLLVIALFLTIAYAAIRVAAHTQDAFVRYTTFGIVVWLLGQMIINVGMVLALLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGIPLPLVSYGGSALVPSLVALGLLIGFARREPEAARALAQRKKARSAGLSAGRLS
HHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTANPLDPVERARPVGRRSVGGWYAAVRHALDRPLTAYYLLLGASALLLTIGLIMVLSA
CCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SSVYSYEKNGSSYAVVERQLLWVLIGIPCAWIASRLPHSVLRRFAWLALIVSIVLLALTQ
HHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGLGRTVNGNTNWLGVGPFVVQPAEIAKLSIVLWAAHVYALKEKRLRSLHEVFVPVVPGM
HCCCCEECCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVVVGLVVLGHDLGTALVLMAILLAMLWVVGAPGRLFSVSLTVIGVVAIWLASTSPERRE
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
RLTNFADPFKDFHNAGWQPAHGLYALSHGGVFGQGLGASQQKWGNLPEAHTDFIFAVLGE
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHH
ELGLVGTLLVIALFLTIAYAAIRVAAHTQDAFVRYTTFGIVVWLLGQMIINVGMVLALLP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGIPLPLVSYGGSALVPSLVALGLLIGFARREPEAARALAQRKKARSAGLSAGRLS
HHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]