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The map label for this gene is murG

Identifier: 119717287

GI number: 119717287

Start: 3260419

End: 3261516

Strand: Reverse

Name: murG

Synonym: Noca_3063

Alternate gene names: 119717287

Gene position: 3261516-3260419 (Counterclockwise)

Preceding gene: 119717288

Following gene: 119717286

Centisome position: 65.42

GC content: 76.14

Gene sequence:

>1098_bases
ATGCGCGTTCTCCTCGCCGGCGGCGGCACCGCCGGCCACACCTCGCCCCTGCTCGCGACCGCCGACGCCCTGCGCCGCCT
CGAGCCCGACGTCGAGATCACCTGTCTCGGGACGCCCCGCGGCCTGGAGAACAAGGTGGTCCCCGAGGCGGGCTACCCGC
TCGAGCTGATCCCGCCGGTGCCGCTGCCGCGCCGGCCCGGCGCCGACCTGCTCAAGGTCCCGTTCCGGCTGCGGGCGGCG
GTCCGGGCGACGCATGCCGTGCTCGACCGGGTCCGGCCCGACGTGGTCGTCGGCTACGGCGGCTACGTCTCCATGCCGGC
GTACGTCGCGACCCGCAAGCGGGGGATCCCGCTGGTCGTCCACGAGCAGAACACCGTGCCCGGGCTGGCCAACCGCGCAG
GCGCGCGGTTCGCGCAGCGGGTCGCGGTGAGCTTCCCGGACACGCCGTTGCGCAACGCCGAGTACGTCGGGCTCCCCATC
CGTCCGATGATCTCCGGCCTGGACCGCGCGGCCCGGCGGGCCGAGGCGCGGGCCTTCTTCGGGCTCGACCCCGACCGCCC
CACGCTGCTGGTCACCGGCGGCTCCCAGGGTGCCCGCCGGCTCAACCAGGCGGTCTCGGCCGCCGCGGGGGCGCTCGCCG
CCACCGGTGTCCAGGTGCTGCACGCCCAGGGCAAGCACGGCGGCGCCGACCCGCAGCCGGGTGCCGAGGAGACCGGCGTC
CCCTACGTCGTCGTGGAGTACATCGACCGGATGGACCTCGCCTACGCCGCGGCCGACCTGGTGATCTGCCGGGCCGGCGC
CAACAGCGTGACCGAGGCGGCAGCCGTCGGCCTGCCCGCGGTCTTCGTGCCGCTGCCGATCGGCAACGGCGAGCAGGAAC
GCAACGCGCGGCCGGTGATCGACGCCGGCGGCGGGATCCTCGTCAAGGACGCCGACCTCACCACCGACTGGGTGGTCGGC
ACCGTCCCGCCCCTCGTCGCCGACGCCGAGCGGCTGGCCGCGATGGGTGCCGCCGCGGCCGCGCTGATCCCGCGCGACGC
CGACGAGCGGCTGGCCCGGATCGTGCTCGAGCTCGGCCTCGGATCGTCCGCCCGATGA

Upstream 100 bases:

>100_bases
TTCGCGCGCCGCGAGCCGGAGGCCGCCCGCGCCCTGGCCCAGCGCAAGAAGGCCCGCTCCGCCGGGCTCTCCGCGGGTCG
GCTCTCCTAGGCTGGTGCCG

Downstream 100 bases:

>100_bases
GGCTGCCCGTCCCCGACCAGGTGCTGCCCGCCGACCGGCTCGGACGGGTGCACTTCGTCGGCATCGGTGGCGCCGGCCTG
TCCGGCATCGCCCGGATCAT

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MRVLLAGGGTAGHTSPLLATADALRRLEPDVEITCLGTPRGLENKVVPEAGYPLELIPPVPLPRRPGADLLKVPFRLRAA
VRATHAVLDRVRPDVVVGYGGYVSMPAYVATRKRGIPLVVHEQNTVPGLANRAGARFAQRVAVSFPDTPLRNAEYVGLPI
RPMISGLDRAARRAEARAFFGLDPDRPTLLVTGGSQGARRLNQAVSAAAGALAATGVQVLHAQGKHGGADPQPGAEETGV
PYVVVEYIDRMDLAYAAADLVICRAGANSVTEAAAVGLPAVFVPLPIGNGEQERNARPVIDAGGGILVKDADLTTDWVVG
TVPPLVADAERLAAMGAAAAALIPRDADERLARIVLELGLGSSAR

Sequences:

>Translated_365_residues
MRVLLAGGGTAGHTSPLLATADALRRLEPDVEITCLGTPRGLENKVVPEAGYPLELIPPVPLPRRPGADLLKVPFRLRAA
VRATHAVLDRVRPDVVVGYGGYVSMPAYVATRKRGIPLVVHEQNTVPGLANRAGARFAQRVAVSFPDTPLRNAEYVGLPI
RPMISGLDRAARRAEARAFFGLDPDRPTLLVTGGSQGARRLNQAVSAAAGALAATGVQVLHAQGKHGGADPQPGAEETGV
PYVVVEYIDRMDLAYAAADLVICRAGANSVTEAAAVGLPAVFVPLPIGNGEQERNARPVIDAGGGILVKDADLTTDWVVG
TVPPLVADAERLAAMGAAAAALIPRDADERLARIVLELGLGSSAR
>Mature_365_residues
MRVLLAGGGTAGHTSPLLATADALRRLEPDVEITCLGTPRGLENKVVPEAGYPLELIPPVPLPRRPGADLLKVPFRLRAA
VRATHAVLDRVRPDVVVGYGGYVSMPAYVATRKRGIPLVVHEQNTVPGLANRAGARFAQRVAVSFPDTPLRNAEYVGLPI
RPMISGLDRAARRAEARAFFGLDPDRPTLLVTGGSQGARRLNQAVSAAAGALAATGVQVLHAQGKHGGADPQPGAEETGV
PYVVVEYIDRMDLAYAAADLVICRAGANSVTEAAAVGLPAVFVPLPIGNGEQERNARPVIDAGGGILVKDADLTTDWVVG
TVPPLVADAERLAAMGAAAAALIPRDADERLARIVLELGLGSSAR

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=360, Percent_Identity=38.3333333333333, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_NOCSJ (A1SL80)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_924252.1
- ProteinModelPortal:   A1SL80
- STRING:   A1SL80
- GeneID:   4600180
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_3063
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- PhylomeDB:   A1SL80
- BioCyc:   NSP35761:NOCA_3063-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38009; Mature: 38009

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLAGGGTAGHTSPLLATADALRRLEPDVEITCLGTPRGLENKVVPEAGYPLELIPPV
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCC
PLPRRPGADLLKVPFRLRAAVRATHAVLDRVRPDVVVGYGGYVSMPAYVATRKRGIPLVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHCCCCEEEE
HEQNTVPGLANRAGARFAQRVAVSFPDTPLRNAEYVGLPIRPMISGLDRAARRAEARAFF
ECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHEEE
GLDPDRPTLLVTGGSQGARRLNQAVSAAAGALAATGVQVLHAQGKHGGADPQPGAEETGV
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCCCCC
PYVVVEYIDRMDLAYAAADLVICRAGANSVTEAAAVGLPAVFVPLPIGNGEQERNARPVI
CEEHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHCCCCCEE
DAGGGILVKDADLTTDWVVGTVPPLVADAERLAAMGAAAAALIPRDADERLARIVLELGL
ECCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GSSAR
CCCCC
>Mature Secondary Structure
MRVLLAGGGTAGHTSPLLATADALRRLEPDVEITCLGTPRGLENKVVPEAGYPLELIPPV
CEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCC
PLPRRPGADLLKVPFRLRAAVRATHAVLDRVRPDVVVGYGGYVSMPAYVATRKRGIPLVV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCHHHHHHCCCCEEEE
HEQNTVPGLANRAGARFAQRVAVSFPDTPLRNAEYVGLPIRPMISGLDRAARRAEARAFF
ECCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHEEE
GLDPDRPTLLVTGGSQGARRLNQAVSAAAGALAATGVQVLHAQGKHGGADPQPGAEETGV
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCHHEEEECCCCCCCCCCCCCCCCCC
PYVVVEYIDRMDLAYAAADLVICRAGANSVTEAAAVGLPAVFVPLPIGNGEQERNARPVI
CEEHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHCCCCCEE
DAGGGILVKDADLTTDWVVGTVPPLVADAERLAAMGAAAAALIPRDADERLARIVLELGL
ECCCCEEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
GSSAR
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA