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The map label for this gene is coaE [H]

Identifier: 119717205

GI number: 119717205

Start: 3169382

End: 3169972

Strand: Reverse

Name: coaE [H]

Synonym: Noca_2981

Alternate gene names: 119717205

Gene position: 3169972-3169382 (Counterclockwise)

Preceding gene: 119717206

Following gene: 119717202

Centisome position: 63.58

GC content: 73.43

Gene sequence:

>591_bases
ATGCGAGTGGGACTCACCGGCGGCATCGCCTCGGGCAAGAGCACGGTGTCGGCGATCCTGGCCGAGCTGGGCGCGGTGGT
CATCGACGCCGACCGGCTGGCCAGGGAGGTGGTCGCGAAGGGCACGCCGGGCCTGGAGCAGGTGGTGGCCGCCTTCGGCC
CCGAGATCCTCGCGGCCGACGGCGAGATGGACCGGGCGGCGGTGGGCCGGATCGTGTTCGCCGACGAGCGCAAGCGCAAG
GTGCTCGAGGCCATCGTGCACCCGCTGGTCTTCGAGCGGTACGCCGAGCTCGAGGCGGCCGCCCCCGTCGACGGGATCGT
GGTCCACGACATCCCGCTGCTCGCGGAGTCCGGCCGGGTCGCGGACTTCGACGCGGTGATCGTCGTCGACGCGCCGCACG
AGACGCAGGTCGACCGGCTGCTCCGCGACCGGGGGATGACGCGCGCGGATGCCGAGTCGCGGATCGCCGCCCAGGCCACC
CGGGAGCAGCGCCGCGCGATCGCGACGTACGTCATCGAGAACACCGGGACGCGCGAAGACCTCCGCCGGCGGGTGGCGGA
GGTCTTCGAGCAGCTGCGCGTAGGCAGCTAG

Upstream 100 bases:

>100_bases
TGCTCGGTCTCTCGGTGGGTGGCCTGGTGCACCGGCTCCGCGACCGCTCGGAGGTCGCCGCCTGACCGACGCGTCGCGGC
GGCTCGGGCAGGATGACCCC

Downstream 100 bases:

>100_bases
TCAGGCGGCCAGATCAGGCCGCGAGGTCCGGGTCGCCCAAGCGGCGGAGCTTCTGCAGCGCCTCGCGTTCGAGCTGGCGC
ACCCGCTCGGCGGAGATGCC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MRVGLTGGIASGKSTVSAILAELGAVVIDADRLAREVVAKGTPGLEQVVAAFGPEILAADGEMDRAAVGRIVFADERKRK
VLEAIVHPLVFERYAELEAAAPVDGIVVHDIPLLAESGRVADFDAVIVVDAPHETQVDRLLRDRGMTRADAESRIAAQAT
REQRRAIATYVIENTGTREDLRRRVAEVFEQLRVGS

Sequences:

>Translated_196_residues
MRVGLTGGIASGKSTVSAILAELGAVVIDADRLAREVVAKGTPGLEQVVAAFGPEILAADGEMDRAAVGRIVFADERKRK
VLEAIVHPLVFERYAELEAAAPVDGIVVHDIPLLAESGRVADFDAVIVVDAPHETQVDRLLRDRGMTRADAESRIAAQAT
REQRRAIATYVIENTGTREDLRRRVAEVFEQLRVGS
>Mature_196_residues
MRVGLTGGIASGKSTVSAILAELGAVVIDADRLAREVVAKGTPGLEQVVAAFGPEILAADGEMDRAAVGRIVFADERKRK
VLEAIVHPLVFERYAELEAAAPVDGIVVHDIPLLAESGRVADFDAVIVVDAPHETQVDRLLRDRGMTRADAESRIAAQAT
REQRRAIATYVIENTGTREDLRRRVAEVFEQLRVGS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=36.2694300518135, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=36.2694300518135, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI110227607, Length=163, Percent_Identity=34.3558282208589, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI110227605, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI110227603, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI110227601, Length=193, Percent_Identity=31.0880829015544, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI205277394, Length=193, Percent_Identity=31.0880829015544, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1786292, Length=186, Percent_Identity=40.3225806451613, Blast_Score=123, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17554944, Length=196, Percent_Identity=38.265306122449, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=34, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644728, Length=194, Percent_Identity=32.4742268041237, Blast_Score=120, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24658602, Length=194, Percent_Identity=30.9278350515464, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21132; Mature: 21132

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGLTGGIASGKSTVSAILAELGAVVIDADRLAREVVAKGTPGLEQVVAAFGPEILAAD
CCCCCCCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC
GEMDRAAVGRIVFADERKRKVLEAIVHPLVFERYAELEAAAPVDGIVVHDIPLLAESGRV
CCCHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCE
ADFDAVIVVDAPHETQVDRLLRDRGMTRADAESRIAAQATREQRRAIATYVIENTGTRED
ECCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRRRVAEVFEQLRVGS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVGLTGGIASGKSTVSAILAELGAVVIDADRLAREVVAKGTPGLEQVVAAFGPEILAAD
CCCCCCCCCCCCHHHHHHHHHHHHHHEECHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC
GEMDRAAVGRIVFADERKRKVLEAIVHPLVFERYAELEAAAPVDGIVVHDIPLLAESGRV
CCCHHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHCCCCE
ADFDAVIVVDAPHETQVDRLLRDRGMTRADAESRIAAQATREQRRAIATYVIENTGTRED
ECCCEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LRRRVAEVFEQLRVGS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]