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The map label for this gene is pcaI [H]

Identifier: 119715255

GI number: 119715255

Start: 1066499

End: 1067158

Strand: Direct

Name: pcaI [H]

Synonym: Noca_1014

Alternate gene names: 119715255

Gene position: 1066499-1067158 (Clockwise)

Preceding gene: 119715254

Following gene: 119715256

Centisome position: 21.39

GC content: 72.88

Gene sequence:

>660_bases
GTGACCGCCACCATCTGCGCCACGGCCGCGGAGGCGGTGGCCGACATCCGGGACGGCGCCGTCGTCCTCGTCGGCGGCTT
CGGCATGGCCGGGATGCCGGTCGAGCTGGTCGACGCCGTCATCGAGCAGGGCGCCACCGACCTCACCGTGGTCTCGAACA
ACGCCGGGAACGGCGACACCGGCCTGGCCGCGCTGCTGGCGAAGGGCCGGGTCCGCAAGGTCGTCTGCTCGTTCCCACGC
CAGCACGACTCGTGGGTCTTCGACGAGCTCTACCGCACGGGCCGGATCGAGCTGGAGCTGGTGCCGCAGGGCAACCTCGC
CGAGCGGCTGCGCGCCGCCGGTGCGGGCATCGGCGCGTTCTTCACCCCGACCGGCGCAGGCACCCCGCTGGCCGAGGGCA
AGGAGACCCGCGAGATCGACGGGCGCCTGCACGTGCTGGAGCTCCCGATCCGCGGCGATGTCGCCCTGGTCGCGGCGCAC
CGGGCCGACCGGATGGGCAACCTCGTGTACCGCAAGACCGCTCGCAACTTCGGCCCGGTGATGGCGACCGCCGCGAGCAG
CACGGTGGTCCAGGTGCGCGAGGTCGTCGAGCCCGGCGCGCTCGACCCTGAGGCGATCGTCACGCCGAGCATCTACGTCG
ACAAGGTGGTGGCGGTGTGA

Upstream 100 bases:

>100_bases
AGTCCGGCGAGCGCTGGGGCGTGGCCGCGATCTGCATCGGGGTCGGCCAGGCCCTGGCCGTCGTCCTGGAGAACGTGTCC
ACGCAGACCGGGGCGCGGGC

Downstream 100 bases:

>100_bases
GCGGCGGGCAGGCACTGACCCGGGACGACATGGCGGCGCTGGTCGCGCGCGACATCCCGCCCGGCTCTTACGTCAATCTC
GGCATCGGCCTGCCCACGCT

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTATICATAAEAVADIRDGAVVLVGGFGMAGMPVELVDAVIEQGATDLTVVSNNAGNGDTGLAALLAKGRVRKVVCSFPR
QHDSWVFDELYRTGRIELELVPQGNLAERLRAAGAGIGAFFTPTGAGTPLAEGKETREIDGRLHVLELPIRGDVALVAAH
RADRMGNLVYRKTARNFGPVMATAASSTVVQVREVVEPGALDPEAIVTPSIYVDKVVAV

Sequences:

>Translated_219_residues
MTATICATAAEAVADIRDGAVVLVGGFGMAGMPVELVDAVIEQGATDLTVVSNNAGNGDTGLAALLAKGRVRKVVCSFPR
QHDSWVFDELYRTGRIELELVPQGNLAERLRAAGAGIGAFFTPTGAGTPLAEGKETREIDGRLHVLELPIRGDVALVAAH
RADRMGNLVYRKTARNFGPVMATAASSTVVQVREVVEPGALDPEAIVTPSIYVDKVVAV
>Mature_218_residues
TATICATAAEAVADIRDGAVVLVGGFGMAGMPVELVDAVIEQGATDLTVVSNNAGNGDTGLAALLAKGRVRKVVCSFPRQ
HDSWVFDELYRTGRIELELVPQGNLAERLRAAGAGIGAFFTPTGAGTPLAEGKETREIDGRLHVLELPIRGDVALVAAHR
ADRMGNLVYRKTARNFGPVMATAASSTVVQVREVVEPGALDPEAIVTPSIYVDKVVAV

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=46.6666666666667, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI11545841, Length=235, Percent_Identity=45.531914893617, Blast_Score=180, Evalue=9e-46,
Organism=Escherichia coli, GI1788551, Length=218, Percent_Identity=43.5779816513761, Blast_Score=183, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=237, Percent_Identity=43.0379746835443, Blast_Score=189, Evalue=7e-49,
Organism=Drosophila melanogaster, GI21358325, Length=230, Percent_Identity=41.7391304347826, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24655794, Length=230, Percent_Identity=41.7391304347826, Blast_Score=178, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 22904; Mature: 22772

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATICATAAEAVADIRDGAVVLVGGFGMAGMPVELVDAVIEQGATDLTVVSNNAGNGDT
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCH
GLAALLAKGRVRKVVCSFPRQHDSWVFDELYRTGRIELELVPQGNLAERLRAAGAGIGAF
HHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCEE
FTPTGAGTPLAEGKETREIDGRLHVLELPIRGDVALVAAHRADRMGNLVYRKTARNFGPV
ECCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEEHHHHHHCCHHHHHHHHCCCCE
MATAASSTVVQVREVVEPGALDPEAIVTPSIYVDKVVAV
EEHHCCHHHHHHHHHHCCCCCCCCCEECCCHHHHHEECC
>Mature Secondary Structure 
TATICATAAEAVADIRDGAVVLVGGFGMAGMPVELVDAVIEQGATDLTVVSNNAGNGDT
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCH
GLAALLAKGRVRKVVCSFPRQHDSWVFDELYRTGRIELELVPQGNLAERLRAAGAGIGAF
HHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCEE
FTPTGAGTPLAEGKETREIDGRLHVLELPIRGDVALVAAHRADRMGNLVYRKTARNFGPV
ECCCCCCCCCCCCCCCHHHCCEEEEEEECCCCCEEEEEEHHHHHHCCHHHHHHHHCCCCE
MATAASSTVVQVREVVEPGALDPEAIVTPSIYVDKVVAV
EEHHCCHHHHHHHHHHCCCCCCCCCEECCCHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]