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The map label for this gene is coaA

Identifier: 119715140

GI number: 119715140

Start: 934760

End: 935749

Strand: Reverse

Name: coaA

Synonym: Noca_0895

Alternate gene names: 119715140

Gene position: 935749-934760 (Counterclockwise)

Preceding gene: 119715143

Following gene: 119715133

Centisome position: 18.77

GC content: 70.2

Gene sequence:

>990_bases
ATGCCTGCCCAAGGGCCGTCCCACGGCGAGCTGCCCCCCGCCGACGCCGGCCGGGAGTCCTCTCCCTACCTGGAGCTGGA
CCGCTCCGCCTGGGCCGCGCTCGCCAGCGAGGTCGAGAACCCCCTCAGCGCCGAGGAGATCCGCCGGCTGCGCGGCCTCG
GCGACCAGCTCGACCTCGACGAGGTGCAGCAGATCTACCTGCCGGTCTCCCGGCTGCTCAGCCTGTACGTCGAGTCCGCG
GGCCGGCTGTACCGCGCCCAGGAGGAGTTCCTGCACCAGGACCAGCCGCCGCGCACCCCGTTCGTGATCGGCCTGGCCGG
CTCGGTCGCGGTCGGCAAGTCCACGACCGCGCGGGTGCTGCAGGAGATGCTGGCCCACTGGCCCCAGCACCCGAACGTCG
CCCTGGTCACCACGGACGGCTTCTTGTACCCCAACGCCGAGCTCGAGCGGCGCGGCCTGCTGGAGCGCAAGGGGTTCCCG
GAGTCCTACGACCGCCGGGCCCTGCTGAAGTTCGTGGTCGACATCAAGTCCGGGAAGGACGAGGTGCTGGCGCCGACGTA
CTCCCACCTCGTCTACGACGTCGTGCCGGACGAGAAGGTCGTCATCCGCCGCCCCGACATCGTCATCGTCGAGGGGCTCA
ACGTGCTCCAGCCGGCCCGGGTGCGCGACGACGGGCGGACCGGCCTGACCTTGAGCGACTTCTTCGACTTCAGCGTGTAC
GTCGACGCCAAGACCAGCACGATCCGCGACTGGTACGTGTCCCGCTTCCTGCGGCTGCGCGAGACGGCGTTCCAGGACAC
CGGCTCCTACTTCGCCAAGTACGCCACCTTGTCGATCGAGGAGGCGATGGCCGAGGCGGAGCGGATCTGGGACACGATCA
ACGGCCCCAACCTGGCCCAGAACGTGCTGCCCACCCGCTCGCGCGCCACGCTGGTGCTGCGCAAGGACCGGGACCACTCG
GTCCGCTACGTCCGCCTGCGCAAGCTATAG

Upstream 100 bases:

>100_bases
CCCTCGACCACGACGTCCTGCGCCGCCTTCTGGCCCACGTAACCGACGATCCCGCACACGGGTGTCACTGTAACGGCGGG
GCTTTGCAAGAATCGCGTCC

Downstream 100 bases:

>100_bases
CAGCAGGCTCGCGACGATCGCCTCGACCCGCTCCGCGGGCAGCGTTCCCGGCGCGCCGGCGTCGGCCACGAGGACCACCC
GGACCTCGCCGGCACGCACC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPAQGPSHGELPPADAGRESSPYLELDRSAWAALASEVENPLSAEEIRRLRGLGDQLDLDEVQQIYLPVSRLLSLYVESA
GRLYRAQEEFLHQDQPPRTPFVIGLAGSVAVGKSTTARVLQEMLAHWPQHPNVALVTTDGFLYPNAELERRGLLERKGFP
ESYDRRALLKFVVDIKSGKDEVLAPTYSHLVYDVVPDEKVVIRRPDIVIVEGLNVLQPARVRDDGRTGLTLSDFFDFSVY
VDAKTSTIRDWYVSRFLRLRETAFQDTGSYFAKYATLSIEEAMAEAERIWDTINGPNLAQNVLPTRSRATLVLRKDRDHS
VRYVRLRKL

Sequences:

>Translated_329_residues
MPAQGPSHGELPPADAGRESSPYLELDRSAWAALASEVENPLSAEEIRRLRGLGDQLDLDEVQQIYLPVSRLLSLYVESA
GRLYRAQEEFLHQDQPPRTPFVIGLAGSVAVGKSTTARVLQEMLAHWPQHPNVALVTTDGFLYPNAELERRGLLERKGFP
ESYDRRALLKFVVDIKSGKDEVLAPTYSHLVYDVVPDEKVVIRRPDIVIVEGLNVLQPARVRDDGRTGLTLSDFFDFSVY
VDAKTSTIRDWYVSRFLRLRETAFQDTGSYFAKYATLSIEEAMAEAERIWDTINGPNLAQNVLPTRSRATLVLRKDRDHS
VRYVRLRKL
>Mature_328_residues
PAQGPSHGELPPADAGRESSPYLELDRSAWAALASEVENPLSAEEIRRLRGLGDQLDLDEVQQIYLPVSRLLSLYVESAG
RLYRAQEEFLHQDQPPRTPFVIGLAGSVAVGKSTTARVLQEMLAHWPQHPNVALVTTDGFLYPNAELERRGLLERKGFPE
SYDRRALLKFVVDIKSGKDEVLAPTYSHLVYDVVPDEKVVIRRPDIVIVEGLNVLQPARVRDDGRTGLTLSDFFDFSVYV
DAKTSTIRDWYVSRFLRLRETAFQDTGSYFAKYATLSIEEAMAEAERIWDTINGPNLAQNVLPTRSRATLVLRKDRDHSV
RYVRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=308, Percent_Identity=53.2467532467532, Blast_Score=330, Evalue=9e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_NOCSJ (A1SF33)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922105.1
- ProteinModelPortal:   A1SF33
- SMR:   A1SF33
- STRING:   A1SF33
- GeneID:   4599902
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_0895
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- PhylomeDB:   A1SF33
- ProtClustDB:   PRK05439
- BioCyc:   NSP35761:NOCA_0895-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 37221; Mature: 37089

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQGPSHGELPPADAGRESSPYLELDRSAWAALASEVENPLSAEEIRRLRGLGDQLDLD
CCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
EVQQIYLPVSRLLSLYVESAGRLYRAQEEFLHQDQPPRTPFVIGLAGSVAVGKSTTARVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCHHHHHH
QEMLAHWPQHPNVALVTTDGFLYPNAELERRGLLERKGFPESYDRRALLKFVVDIKSGKD
HHHHHHCCCCCCEEEEEECCEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCC
EVLAPTYSHLVYDVVPDEKVVIRRPDIVIVEGLNVLQPARVRDDGRTGLTLSDFFDFSVY
CCCCCHHHHHEEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEE
VDAKTSTIRDWYVSRFLRLRETAFQDTGSYFAKYATLSIEEAMAEAERIWDTINGPNLAQ
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NVLPTRSRATLVLRKDRDHSVRYVRLRKL
HHCCCCCCEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
PAQGPSHGELPPADAGRESSPYLELDRSAWAALASEVENPLSAEEIRRLRGLGDQLDLD
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHH
EVQQIYLPVSRLLSLYVESAGRLYRAQEEFLHQDQPPRTPFVIGLAGSVAVGKSTTARVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCCHHHHHH
QEMLAHWPQHPNVALVTTDGFLYPNAELERRGLLERKGFPESYDRRALLKFVVDIKSGKD
HHHHHHCCCCCCEEEEEECCEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHCCCCC
EVLAPTYSHLVYDVVPDEKVVIRRPDIVIVEGLNVLQPARVRDDGRTGLTLSDFFDFSVY
CCCCCHHHHHEEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHCCCEEEE
VDAKTSTIRDWYVSRFLRLRETAFQDTGSYFAKYATLSIEEAMAEAERIWDTINGPNLAQ
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NVLPTRSRATLVLRKDRDHSVRYVRLRKL
HHCCCCCCEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA