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The map label for this gene is cofC [H]

Identifier: 119715110

GI number: 119715110

Start: 904225

End: 904857

Strand: Direct

Name: cofC [H]

Synonym: Noca_0865

Alternate gene names: 119715110

Gene position: 904225-904857 (Clockwise)

Preceding gene: 119715109

Following gene: 119715111

Centisome position: 18.14

GC content: 76.94

Gene sequence:

>633_bases
ATGGCCCGTTGGTGCGCGGTCGTGCCGCAGAAGGCGCTCGCGAGCGCCAAGAGTCGCACCGGCCTGCCGGACGCACAGCG
CCGAGAGCTCGCCACCGCGTTGCTGCGCGACACGGTCGCGGCGCTCGAGGAGACCCCGGCCGTCGATGCGGTCCTGGTGC
TCTGGGACGACGAGCTGGATCGGGTCGTCCTGCCGGCCGTCCGCTCGGTCCCGGTCGCCGGCCTCGGCCTGAACGCCTCT
CTCGAACGAGGCGCTGCGGTCGCGCTCGACCGGCTGCCCGGCCGCGGCATCGTGGTCGTCCCCGGCGACCTACCGGCCCT
CGACCCCGCCGAGCTGGGCCGCTGCCTGGCCGAGGCGGCACGGTTCCGCCGAGCGTTCCTGCCGGACAGGGACGGCACCG
GGACCACCGTGCTGACCGCTGGGGCCGGGGACCTCCGCCCGGCGTACGGCGCGGGCTCCGCCTCCCGGCACGCCGCGACC
GGCGCCGTGTCGTTGGACGTGGCCGGGGTGGACACCGTGCGCGCGGACGTGGACGACCTCGACTCGCTCGCCGCCGTCCT
GGATGGACGCTGCGGTCGGCACACGCGGGCGGCCGCGGCGCGCCTGGGCCCGGCGCTGGAGGCTGTGGGATGA

Upstream 100 bases:

>100_bases
CGCGCCAGCTCGAGCCGCTGACCGCTGTGCTGATCTCGGTCAACCGGGCGTACAAGGCGCACTCGGGCATCCGGGTGACC
GGGCTCCGACCAGTCGTCTG

Downstream 100 bases:

>100_bases
GGCCGGCCACCGGGGAGGTGCCCGTCCGGGTGCGTGCCGAGATCGACCTGACGATGGCGGCCGGCGGCCGGACCCTCCCG
GGCCGGGTACACACGTTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: LP guanylyltransferase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MARWCAVVPQKALASAKSRTGLPDAQRRELATALLRDTVAALEETPAVDAVLVLWDDELDRVVLPAVRSVPVAGLGLNAS
LERGAAVALDRLPGRGIVVVPGDLPALDPAELGRCLAEAARFRRAFLPDRDGTGTTVLTAGAGDLRPAYGAGSASRHAAT
GAVSLDVAGVDTVRADVDDLDSLAAVLDGRCGRHTRAAAARLGPALEAVG

Sequences:

>Translated_210_residues
MARWCAVVPQKALASAKSRTGLPDAQRRELATALLRDTVAALEETPAVDAVLVLWDDELDRVVLPAVRSVPVAGLGLNAS
LERGAAVALDRLPGRGIVVVPGDLPALDPAELGRCLAEAARFRRAFLPDRDGTGTTVLTAGAGDLRPAYGAGSASRHAAT
GAVSLDVAGVDTVRADVDDLDSLAAVLDGRCGRHTRAAAARLGPALEAVG
>Mature_209_residues
ARWCAVVPQKALASAKSRTGLPDAQRRELATALLRDTVAALEETPAVDAVLVLWDDELDRVVLPAVRSVPVAGLGLNASL
ERGAAVALDRLPGRGIVVVPGDLPALDPAELGRCLAEAARFRRAFLPDRDGTGTTVLTAGAGDLRPAYGAGSASRHAATG
AVSLDVAGVDTVRADVDDLDSLAAVLDGRCGRHTRAAAARLGPALEAVG

Specific function: Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor [H]

COG id: COG1920

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CofC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002835 [H]

Pfam domain/function: PF01983 DUF121 [H]

EC number: =2.7.7.68 [H]

Molecular weight: Translated: 21508; Mature: 21376

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARWCAVVPQKALASAKSRTGLPDAQRRELATALLRDTVAALEETPAVDAVLVLWDDELD
CCCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
RVVLPAVRSVPVAGLGLNASLERGAAVALDRLPGRGIVVVPGDLPALDPAELGRCLAEAA
HHHHHHHHHCCCCCCCCCCCHHCCHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
RFRRAFLPDRDGTGTTVLTAGAGDLRPAYGAGSASRHAATGAVSLDVAGVDTVRADVDDL
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCHHHH
DSLAAVLDGRCGRHTRAAAARLGPALEAVG
HHHHHHHCCCCCCHHHHHHHHHCCHHHHCC
>Mature Secondary Structure 
ARWCAVVPQKALASAKSRTGLPDAQRRELATALLRDTVAALEETPAVDAVLVLWDDELD
CCHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCC
RVVLPAVRSVPVAGLGLNASLERGAAVALDRLPGRGIVVVPGDLPALDPAELGRCLAEAA
HHHHHHHHHCCCCCCCCCCCHHCCHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHH
RFRRAFLPDRDGTGTTVLTAGAGDLRPAYGAGSASRHAATGAVSLDVAGVDTVRADVDDL
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHCHHHH
DSLAAVLDGRCGRHTRAAAARLGPALEAVG
HHHHHHHCCCCCCHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]