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The map label for this gene is fno [H]

Identifier: 119715109

GI number: 119715109

Start: 903557

End: 904225

Strand: Direct

Name: fno [H]

Synonym: Noca_0864

Alternate gene names: 119715109

Gene position: 903557-904225 (Clockwise)

Preceding gene: 119715108

Following gene: 119715110

Centisome position: 18.12

GC content: 71.6

Gene sequence:

>669_bases
ATGAGCAGGCAGTCCATCGCGATCATCGGCGGCACCGGCCCGCAGGGCAGGGGCCTGGCCTACCGCCTGGCCACCAGCGG
TCACGAGGTGATCCTCGGCTCCCGTGACGAGGAGCGTGCCCGCTCCGCAGCGGACGAGCTGGCCGTCCGGTTGCCTCCCG
CGGCGTGCATCAGTGGCGCGACCAACCTCGAGGCGGTCCGCAAGGCCGAGGTCGTGCTCCTGGCCGTCCCGTACGACGGC
CACGACGAGCTCGTCGCGTCCCTGCGCGACGTGGTCGAGGGCAAGATCGTCATCAGCTGCGTGAACCCGCTCGGCTTCGA
CAAGCAAGGCCCGTTCGGACTCGACGTGCCCACGGGCAGCGCCGCCGAGTCCGCGGCCGCGCTGTTGCCGGGGTCGGCCG
TGATCGGCGCGTTCCACCACCTCTCCGCGGTCACGTTGATCACCGACGAGGAGCTGCTCGAGGACGTGCTGGTGGTCGGT
GACGACGAGGCGGCCAAGGACGTCGTGATCGAGCTCGCTCGCTCCGTCACCGGCCGCCCCGGTATCGCCGCCGGGCGCCT
GCGCCTGGCGCGCCAGCTCGAGCCGCTGACCGCTGTGCTGATCTCGGTCAACCGGGCGTACAAGGCGCACTCGGGCATCC
GGGTGACCGGGCTCCGACCAGTCGTCTGA

Upstream 100 bases:

>100_bases
CGACGAGCGAGCCGAAGCGGCCCTGAGGTTCGACGGAGCCACCCGGACGCTGCTGCCGATGGTCACCAACGCCCCCTGAG
ATCCACCGAGAGGAACACAG

Downstream 100 bases:

>100_bases
TGGCCCGTTGGTGCGCGGTCGTGCCGCAGAAGGCGCTCGCGAGCGCCAAGAGTCGCACCGGCCTGCCGGACGCACAGCGC
CGAGAGCTCGCCACCGCGTT

Product: reduced coenzyme F420:NADP oxidoreductase

Products: NA

Alternate protein names: F420H2:NADP oxidoreductase [H]

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSRQSIAIIGGTGPQGRGLAYRLATSGHEVILGSRDEERARSAADELAVRLPPAACISGATNLEAVRKAEVVLLAVPYDG
HDELVASLRDVVEGKIVISCVNPLGFDKQGPFGLDVPTGSAAESAAALLPGSAVIGAFHHLSAVTLITDEELLEDVLVVG
DDEAAKDVVIELARSVTGRPGIAAGRLRLARQLEPLTAVLISVNRAYKAHSGIRVTGLRPVV

Sequences:

>Translated_222_residues
MSRQSIAIIGGTGPQGRGLAYRLATSGHEVILGSRDEERARSAADELAVRLPPAACISGATNLEAVRKAEVVLLAVPYDG
HDELVASLRDVVEGKIVISCVNPLGFDKQGPFGLDVPTGSAAESAAALLPGSAVIGAFHHLSAVTLITDEELLEDVLVVG
DDEAAKDVVIELARSVTGRPGIAAGRLRLARQLEPLTAVLISVNRAYKAHSGIRVTGLRPVV
>Mature_221_residues
SRQSIAIIGGTGPQGRGLAYRLATSGHEVILGSRDEERARSAADELAVRLPPAACISGATNLEAVRKAEVVLLAVPYDGH
DELVASLRDVVEGKIVISCVNPLGFDKQGPFGLDVPTGSAAESAAALLPGSAVIGAFHHLSAVTLITDEELLEDVLVVGD
DEAAKDVVIELARSVTGRPGIAAGRLRLARQLEPLTAVLISVNRAYKAHSGIRVTGLRPVV

Specific function: Catalyzes the reduction of NADP(+) with F420H(2) via hydride transfer, and the reverse reaction, i.e. the reduction of F420 with NADPH. Probably functions in the regeneration of NADPH required in biosynthetic reactions [H]

COG id: COG2085

COG function: function code R; Predicted dinucleotide-binding enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the F420-dependent NADP reductase family [H]

Homologues:

Organism=Homo sapiens, GI100815815, Length=204, Percent_Identity=28.4313725490196, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR004455
- InterPro:   IPR010185 [H]

Pfam domain/function: PF03807 F420_oxidored [H]

EC number: NA

Molecular weight: Translated: 23076; Mature: 22945

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQSIAIIGGTGPQGRGLAYRLATSGHEVILGSRDEERARSAADELAVRLPPAACISGA
CCCCEEEEEECCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHEEECCCHHHHCCC
TNLEAVRKAEVVLLAVPYDGHDELVASLRDVVEGKIVISCVNPLGFDKQGPFGLDVPTGS
CCHHHHHCEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCC
AAESAAALLPGSAVIGAFHHLSAVTLITDEELLEDVLVVGDDEAAKDVVIELARSVTGRP
CHHHHHHHCCCHHHHHHHHHHHEEEEEECHHHHHHHEEECCCHHHHHHHHHHHHHHCCCC
GIAAGRLRLARQLEPLTAVLISVNRAYKAHSGIRVTGLRPVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
>Mature Secondary Structure 
SRQSIAIIGGTGPQGRGLAYRLATSGHEVILGSRDEERARSAADELAVRLPPAACISGA
CCCEEEEEECCCCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHEEECCCHHHHCCC
TNLEAVRKAEVVLLAVPYDGHDELVASLRDVVEGKIVISCVNPLGFDKQGPFGLDVPTGS
CCHHHHHCEEEEEEEECCCCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCC
AAESAAALLPGSAVIGAFHHLSAVTLITDEELLEDVLVVGDDEAAKDVVIELARSVTGRP
CHHHHHHHCCCHHHHHHHHHHHEEEEEECHHHHHHHEEECCCHHHHHHHHHHHHHHCCCC
GIAAGRLRLARQLEPLTAVLISVNRAYKAHSGIRVTGLRPVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]