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The map label for this gene is ksdD [H]

Identifier: 119386254

GI number: 119386254

Start: 691538

End: 693247

Strand: Direct

Name: ksdD [H]

Synonym: Pden_3543

Alternate gene names: 119386254

Gene position: 691538-693247 (Clockwise)

Preceding gene: 119386253

Following gene: 119386255

Centisome position: 39.97

GC content: 68.01

Gene sequence:

>1710_bases
ATGCCGAAGCCTGATCTGCCGGACCTGCCCGATACCTGCGACCTTCTGGTCGTGGGTTCGGGTGCCGCGGGCATGGCGGC
GGCGATCTCTGCCCATCATCACGGGTTGAAGCCGGTCATCGTCGAGAAGTCCGAATTCTTCGGCGGCTCCACCGCCGTTT
CCGGCGGCGCGATCTGGGTGCCGTGCAATCCGATCGCCGCGGCGGCCGGCATGACCGACGACCGCGAGGCGGCGCGCGCC
TATATCCGGGGCGAGACGGGCAATCGCTTCAATGCCGAGCTGGTGGACGCCTTTCTCGACAAGAGCCCCGAGGCCATCGG
CTTTTTCCACGAAAGAACCGCGCTCAAGATGGCGCATCGCGCGCTGTCGCCCGACTATCATTCGGATGCGCCGGGTGCGA
CCGAAGGCGGCCGGGCGCTGGACGCGCTGGATTATGACGGCCGCCGGCTGGGGGCGGACCTTTATCGGATGCGCCCGCCC
ATCGCCGATTTCACGATCCTCGGCGGAATGCCGCTGGGGCGCCCGGACATCTTTCACTTCCTGCGCATGACCCGGTCGGT
GAAATCGGCGGCCTATGCGACCGGGGCAGTGCTGCGCTATTTCCGCGACCGGCTGACCTGGGGGCGGAACACGCGGCTGG
TGATGGGCGCGGCGGTCTCGGGGCGCCTGGCCGAGACGGTGTTCGCAAGGAACATCCCGCTTTTTACCGGGCATGAGCTG
GTGCGGCTGCTGCAGGACGAATCCGGGCGGGTCGTCGGGGCCGAACTCAAGGGGCCACGGGGCGTTTGCCGGATCGCGGC
GCATCGCGGCGTGGTTCTTGCGGCGGGCGGCTATCCGCATGATGCGGCGCGTCGGGCGCAAAGCTTCGAGCATGTCAGGC
GCGGCCTGCCGCATTATTCGATGTCGCCGGTCTCGGGCACCGGCGGCGGGATCGCCGCGGCCGAGGCCGTCGGAGCGGCC
TTTGTCGACACCAACCCCAATGCCGGTTTCTGGACGCCGGTTTCGCTCTTGCGCAATGCCGACGGATCGGTGCGGCCCTT
CCCGCATCTTTTCCTGGACCGTGCCAAGCCCGGCGTGATCGCCGTCGGCCATGACGGCCGGCGCTTCGTCAACGAGGCTT
CCAGCTATCATGACTTCGTGCAGGGATTGATCGCGAAGCTGCTGGCCGACGGAGAGAAATCCGCCTGGCTGGTCGCCGAT
CACCGGGCGATGCGGCGCTATGGGCTGGGTGCCGCGCATGCCTTTCCGGCGCGGATCGGCCGGCATGTCGCCAGCGGCTA
TCTGAAGCGCGACGCGACGCTGGAGGGGCTGGCCCGGCAATGCGGCATCGACGTCGCGACGTTCCGGCAGACGGTCGCCC
TGTTCAACGAGGCGGCGGCACGCGGCGAAGACCCGGCCTTCGGCAAGGGATCGACCAGCTATCAGCGCTATCTGGGCGAT
GGCGAGAACCGGCCGAACCCCTGCCTGCGCCCGCTGGAGGGGCCGTTCTACGCCGTCGAGATCTATCCGGGCGACATCGG
CACCTCTATGGGCCTGGACATCACGGCGAAAGGCGAGGTCAGGGACAGCCGGGGCAGGACGATACCCGGCCTCTATGCCT
GCGGCAACGACATCAATTCGGTGATGTCCGGCGCCTATCCCGGGCCGGGCATCACGCTGGGTCCGGCGCTGACCTTCGGA
TATGTCATCGGGCAATCGGCGGCCGCATGA

Upstream 100 bases:

>100_bases
CGCTTCCTCGCCTCGGACGAGGCGTCGTTCATCACCGGCCATGTCCTGACGGTGGACGGGGGCTGGGCCATCGGCCGCTT
CCCGCGCCAGGAGGCCATCC

Downstream 100 bases:

>100_bases
CGTCCGAGCTGATGATCGACCCGGAAGCCGAGCGCGAGATCCGCTTTCTGCTCGGCCGGTATGTGCATCTGCTGGACGCG
GGCGAGGCGACGGCATGGGC

Product: fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein

Products: NA

Alternate protein names: 3-keto-Delta(4)-steroid Delta(1)-dehydrogenase; KSDD; 3-oxo-Delta(4)-steroid 1-dehydrogenase; KSTD [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MPKPDLPDLPDTCDLLVVGSGAAGMAAAISAHHHGLKPVIVEKSEFFGGSTAVSGGAIWVPCNPIAAAAGMTDDREAARA
YIRGETGNRFNAELVDAFLDKSPEAIGFFHERTALKMAHRALSPDYHSDAPGATEGGRALDALDYDGRRLGADLYRMRPP
IADFTILGGMPLGRPDIFHFLRMTRSVKSAAYATGAVLRYFRDRLTWGRNTRLVMGAAVSGRLAETVFARNIPLFTGHEL
VRLLQDESGRVVGAELKGPRGVCRIAAHRGVVLAAGGYPHDAARRAQSFEHVRRGLPHYSMSPVSGTGGGIAAAEAVGAA
FVDTNPNAGFWTPVSLLRNADGSVRPFPHLFLDRAKPGVIAVGHDGRRFVNEASSYHDFVQGLIAKLLADGEKSAWLVAD
HRAMRRYGLGAAHAFPARIGRHVASGYLKRDATLEGLARQCGIDVATFRQTVALFNEAAARGEDPAFGKGSTSYQRYLGD
GENRPNPCLRPLEGPFYAVEIYPGDIGTSMGLDITAKGEVRDSRGRTIPGLYACGNDINSVMSGAYPGPGITLGPALTFG
YVIGQSAAA

Sequences:

>Translated_569_residues
MPKPDLPDLPDTCDLLVVGSGAAGMAAAISAHHHGLKPVIVEKSEFFGGSTAVSGGAIWVPCNPIAAAAGMTDDREAARA
YIRGETGNRFNAELVDAFLDKSPEAIGFFHERTALKMAHRALSPDYHSDAPGATEGGRALDALDYDGRRLGADLYRMRPP
IADFTILGGMPLGRPDIFHFLRMTRSVKSAAYATGAVLRYFRDRLTWGRNTRLVMGAAVSGRLAETVFARNIPLFTGHEL
VRLLQDESGRVVGAELKGPRGVCRIAAHRGVVLAAGGYPHDAARRAQSFEHVRRGLPHYSMSPVSGTGGGIAAAEAVGAA
FVDTNPNAGFWTPVSLLRNADGSVRPFPHLFLDRAKPGVIAVGHDGRRFVNEASSYHDFVQGLIAKLLADGEKSAWLVAD
HRAMRRYGLGAAHAFPARIGRHVASGYLKRDATLEGLARQCGIDVATFRQTVALFNEAAARGEDPAFGKGSTSYQRYLGD
GENRPNPCLRPLEGPFYAVEIYPGDIGTSMGLDITAKGEVRDSRGRTIPGLYACGNDINSVMSGAYPGPGITLGPALTFG
YVIGQSAAA
>Mature_568_residues
PKPDLPDLPDTCDLLVVGSGAAGMAAAISAHHHGLKPVIVEKSEFFGGSTAVSGGAIWVPCNPIAAAAGMTDDREAARAY
IRGETGNRFNAELVDAFLDKSPEAIGFFHERTALKMAHRALSPDYHSDAPGATEGGRALDALDYDGRRLGADLYRMRPPI
ADFTILGGMPLGRPDIFHFLRMTRSVKSAAYATGAVLRYFRDRLTWGRNTRLVMGAAVSGRLAETVFARNIPLFTGHELV
RLLQDESGRVVGAELKGPRGVCRIAAHRGVVLAAGGYPHDAARRAQSFEHVRRGLPHYSMSPVSGTGGGIAAAEAVGAAF
VDTNPNAGFWTPVSLLRNADGSVRPFPHLFLDRAKPGVIAVGHDGRRFVNEASSYHDFVQGLIAKLLADGEKSAWLVADH
RAMRRYGLGAAHAFPARIGRHVASGYLKRDATLEGLARQCGIDVATFRQTVALFNEAAARGEDPAFGKGSTSYQRYLGDG
ENRPNPCLRPLEGPFYAVEIYPGDIGTSMGLDITAKGEVRDSRGRTIPGLYACGNDINSVMSGAYPGPGITLGPALTFGY
VIGQSAAA

Specific function: Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3- ketosteroids. Is also involved in the formation of 1,4- androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to [H]

COG id: COG1053

COG function: function code C; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. 3-oxosteroid dehydrogenase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.3.99.4 [H]

Molecular weight: Translated: 60516; Mature: 60385

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKPDLPDLPDTCDLLVVGSGAAGMAAAISAHHHGLKPVIVEKSEFFGGSTAVSGGAIWV
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEE
PCNPIAAAAGMTDDREAARAYIRGETGNRFNAELVDAFLDKSPEAIGFFHERTALKMAHR
CCCHHHHHCCCCCCHHHHHHEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALSPDYHSDAPGATEGGRALDALDYDGRRLGADLYRMRPPIADFTILGGMPLGRPDIFHF
HCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHCCCCCCEEEECCCCCCCHHHHHH
LRMTRSVKSAAYATGAVLRYFRDRLTWGRNTRLVMGAAVSGRLAETVFARNIPLFTGHEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHH
VRLLQDESGRVVGAELKGPRGVCRIAAHRGVVLAAGGYPHDAARRAQSFEHVRRGLPHYS
HHHHHCCCCCEEEECCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
MSPVSGTGGGIAAAEAVGAAFVDTNPNAGFWTPVSLLRNADGSVRPFPHLFLDRAKPGVI
CCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCCEE
AVGHDGRRFVNEASSYHDFVQGLIAKLLADGEKSAWLVADHRAMRRYGLGAAHAFPARIG
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHH
RHVASGYLKRDATLEGLARQCGIDVATFRQTVALFNEAAARGEDPAFGKGSTSYQRYLGD
HHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
GENRPNPCLRPLEGPFYAVEIYPGDIGTSMGLDITAKGEVRDSRGRTIPGLYACGNDINS
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCHHHH
VMSGAYPGPGITLGPALTFGYVIGQSAAA
HHCCCCCCCCCEECHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKPDLPDLPDTCDLLVVGSGAAGMAAAISAHHHGLKPVIVEKSEFFGGSTAVSGGAIWV
CCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCCCEEEE
PCNPIAAAAGMTDDREAARAYIRGETGNRFNAELVDAFLDKSPEAIGFFHERTALKMAHR
CCCHHHHHCCCCCCHHHHHHEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ALSPDYHSDAPGATEGGRALDALDYDGRRLGADLYRMRPPIADFTILGGMPLGRPDIFHF
HCCCCCCCCCCCCCCCCCEEECCCCCCHHHCCHHHHHCCCCCCEEEECCCCCCCHHHHHH
LRMTRSVKSAAYATGAVLRYFRDRLTWGRNTRLVMGAAVSGRLAETVFARNIPLFTGHEL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCHHHH
VRLLQDESGRVVGAELKGPRGVCRIAAHRGVVLAAGGYPHDAARRAQSFEHVRRGLPHYS
HHHHHCCCCCEEEECCCCCCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCC
MSPVSGTGGGIAAAEAVGAAFVDTNPNAGFWTPVSLLRNADGSVRPFPHLFLDRAKPGVI
CCCCCCCCCCHHHHHHHCEEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCCEE
AVGHDGRRFVNEASSYHDFVQGLIAKLLADGEKSAWLVADHRAMRRYGLGAAHAFPARIG
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCHHHHHHHHHH
RHVASGYLKRDATLEGLARQCGIDVATFRQTVALFNEAAARGEDPAFGKGSTSYQRYLGD
HHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCC
GENRPNPCLRPLEGPFYAVEIYPGDIGTSMGLDITAKGEVRDSRGRTIPGLYACGNDINS
CCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCHHHCCCHHHH
VMSGAYPGPGITLGPALTFGYVIGQSAAA
HHCCCCCCCCCEECHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA