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The map label for this gene is siaT [H]

Identifier: 119386141

GI number: 119386141

Start: 571452

End: 572753

Strand: Direct

Name: siaT [H]

Synonym: Pden_3429

Alternate gene names: 119386141

Gene position: 571452-572753 (Clockwise)

Preceding gene: 119386140

Following gene: 119386142

Centisome position: 33.03

GC content: 64.75

Gene sequence:

>1302_bases
ATGGCAACGATCGTCTTTACCCTGCTTTTCCTGATGGCCGTCCTGCTGGGGTCGGGCATGTGGATCGGCATCGGCCTGAT
CGGCACCGGCATCGGCCTGGTCGAGATATTCAAGCCCAACCTTCCGGCGCTGAAACTGCTGTCGCAGCAAAGCTGGAACA
CCGTGGTCTCGCCCGAGTTGCTGGCGCTGCCGCTGTTCATCCTGATGGCCGAGATCCTGTTTCGCACCCGCATCTCCGAG
GCGCTGTTCAGCGGGCTGTCGCCCTGGCTGCGCCGGGTGCCGGGCCGGTTGAGCCATCTGACGGTGCTGGGCTGCACGCT
GTTCGCCTCGGTCTGCGGCTCGTCGGCGGCGACCACGGCCACGGTCGGGCGCATCACCGCAAAGGAGCTGATCGACCGCG
GCTACAACCGCGATCTGGTCACCGGCAGCCTTGCCGGGGCGGGCACGCTGGGCTTTCTGATCCCGCCCTCGACCATCATG
ATCATCTATGGCGTGATGGCCGAGGAATCGATCCTGAAGCTGTTCATCGCGGGCATCCTGCCCGGCTTCATGCTGGCTGC
GGCCTATATGGGCTATCTGGCGATCCGCTCGATGATGAACCCGTCGCTGGTGGGTGCCCCGCCGCCGCCCAGTTCGCTTT
GGGACAAGATCGTGGCGCTGAAGGACCTGGGTCCGCTGCTGCTCCTGATCCTGGGTGTCATCGGCTCGATGTATGGCGGC
ATTGCCACGCCGACCGAGGCGGCCGCCGTGGGCGTCGCCGCCTCGATGCTGATCGGCTTCCTGCAGCGGACGCTGGACCT
GAAGGGCGTGCTGATCGCCGCCCGGCATGCCGCCGAAAGTTGCGCGATGATCGGGCTGATCATGATCGGCGCCATGTTCC
TGTCCACCGCCATCGGCTATCTGGGCGTGCCGCGCTATATCGCCTCGGAAATCCAGGGCTGGGGCATGTCGCCCTTCATG
CTGATCGTCGTGCTGCTGATCTTCTACGTCATCCTCGGCACGGTGATGGAGGGGCTGGGCATCATCGTCATGACCCTGCC
GATCACCCTGCCTCTGGTCCTGGCGGCCGGCTACGACAAGGTCTGGTTCGGGATCTTCCTGGTGATCGTGGTCGAGATGG
CGCAGATCACCCCGCCGGTGGGCTTCAACCTGACGGTGATCCAGCGTCTGACGGGCGACAGCATGGGGCGCATCACCCGC
GCCACGATGCCGTTCTTCTACATCATGTCGGCATTCGTGCTGCTGATCGCGGTCTTTCCGGGGATCATCGACCTGCTGCC
CGGCATGATGGCGGGACGATAG

Upstream 100 bases:

>100_bases
TGCGGTGCTGTTGACGCTGCAATGCCTGGCGCAGGTCCTGCGCCTGCTGCGCGGCGAGGCGCTGACCTCCGGTCCCGGTC
TGGAATAGGGGAAGCCTCGC

Downstream 100 bases:

>100_bases
GGCAGGGATGCCCGCGGCCCGCACGGGGCCGCGGCGCACGTCACCAGAACAAGAAGAAATGATGCAACCCAAGATCCTAC
CCTGCGGCGATACCGCGCTT

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MATIVFTLLFLMAVLLGSGMWIGIGLIGTGIGLVEIFKPNLPALKLLSQQSWNTVVSPELLALPLFILMAEILFRTRISE
ALFSGLSPWLRRVPGRLSHLTVLGCTLFASVCGSSAATTATVGRITAKELIDRGYNRDLVTGSLAGAGTLGFLIPPSTIM
IIYGVMAEESILKLFIAGILPGFMLAAAYMGYLAIRSMMNPSLVGAPPPPSSLWDKIVALKDLGPLLLLILGVIGSMYGG
IATPTEAAAVGVAASMLIGFLQRTLDLKGVLIAARHAAESCAMIGLIMIGAMFLSTAIGYLGVPRYIASEIQGWGMSPFM
LIVVLLIFYVILGTVMEGLGIIVMTLPITLPLVLAAGYDKVWFGIFLVIVVEMAQITPPVGFNLTVIQRLTGDSMGRITR
ATMPFFYIMSAFVLLIAVFPGIIDLLPGMMAGR

Sequences:

>Translated_433_residues
MATIVFTLLFLMAVLLGSGMWIGIGLIGTGIGLVEIFKPNLPALKLLSQQSWNTVVSPELLALPLFILMAEILFRTRISE
ALFSGLSPWLRRVPGRLSHLTVLGCTLFASVCGSSAATTATVGRITAKELIDRGYNRDLVTGSLAGAGTLGFLIPPSTIM
IIYGVMAEESILKLFIAGILPGFMLAAAYMGYLAIRSMMNPSLVGAPPPPSSLWDKIVALKDLGPLLLLILGVIGSMYGG
IATPTEAAAVGVAASMLIGFLQRTLDLKGVLIAARHAAESCAMIGLIMIGAMFLSTAIGYLGVPRYIASEIQGWGMSPFM
LIVVLLIFYVILGTVMEGLGIIVMTLPITLPLVLAAGYDKVWFGIFLVIVVEMAQITPPVGFNLTVIQRLTGDSMGRITR
ATMPFFYIMSAFVLLIAVFPGIIDLLPGMMAGR
>Mature_432_residues
ATIVFTLLFLMAVLLGSGMWIGIGLIGTGIGLVEIFKPNLPALKLLSQQSWNTVVSPELLALPLFILMAEILFRTRISEA
LFSGLSPWLRRVPGRLSHLTVLGCTLFASVCGSSAATTATVGRITAKELIDRGYNRDLVTGSLAGAGTLGFLIPPSTIMI
IYGVMAEESILKLFIAGILPGFMLAAAYMGYLAIRSMMNPSLVGAPPPPSSLWDKIVALKDLGPLLLLILGVIGSMYGGI
ATPTEAAAVGVAASMLIGFLQRTLDLKGVLIAARHAAESCAMIGLIMIGAMFLSTAIGYLGVPRYIASEIQGWGMSPFML
IVVLLIFYVILGTVMEGLGIIVMTLPITLPLVLAAGYDKVWFGIFLVIVVEMAQITPPVGFNLTVIQRLTGDSMGRITRA
TMPFFYIMSAFVLLIAVFPGIIDLLPGMMAGR

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=364, Percent_Identity=28.2967032967033, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46003; Mature: 45871

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIVFTLLFLMAVLLGSGMWIGIGLIGTGIGLVEIFKPNLPALKLLSQQSWNTVVSPEL
CHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHH
LALPLFILMAEILFRTRISEALFSGLSPWLRRVPGRLSHLTVLGCTLFASVCGSSAATTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
TVGRITAKELIDRGYNRDLVTGSLAGAGTLGFLIPPSTIMIIYGVMAEESILKLFIAGIL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
PGFMLAAAYMGYLAIRSMMNPSLVGAPPPPSSLWDKIVALKDLGPLLLLILGVIGSMYGG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IATPTEAAAVGVAASMLIGFLQRTLDLKGVLIAARHAAESCAMIGLIMIGAMFLSTAIGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVPRYIASEIQGWGMSPFMLIVVLLIFYVILGTVMEGLGIIVMTLPITLPLVLAAGYDK
HCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VWFGIFLVIVVEMAQITPPVGFNLTVIQRLTGDSMGRITRATMPFFYIMSAFVLLIAVFP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIIDLLPGMMAGR
HHHHHHHHHHCCC
>Mature Secondary Structure 
ATIVFTLLFLMAVLLGSGMWIGIGLIGTGIGLVEIFKPNLPALKLLSQQSWNTVVSPEL
HHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCCCCHHH
LALPLFILMAEILFRTRISEALFSGLSPWLRRVPGRLSHLTVLGCTLFASVCGSSAATTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHH
TVGRITAKELIDRGYNRDLVTGSLAGAGTLGFLIPPSTIMIIYGVMAEESILKLFIAGIL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHH
PGFMLAAAYMGYLAIRSMMNPSLVGAPPPPSSLWDKIVALKDLGPLLLLILGVIGSMYGG
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IATPTEAAAVGVAASMLIGFLQRTLDLKGVLIAARHAAESCAMIGLIMIGAMFLSTAIGY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVPRYIASEIQGWGMSPFMLIVVLLIFYVILGTVMEGLGIIVMTLPITLPLVLAAGYDK
HCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
VWFGIFLVIVVEMAQITPPVGFNLTVIQRLTGDSMGRITRATMPFFYIMSAFVLLIAVFP
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIIDLLPGMMAGR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]