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The map label for this gene is macB [H]

Identifier: 119357470

GI number: 119357470

Start: 1897022

End: 1898284

Strand: Direct

Name: macB [H]

Synonym: Cpha266_1669

Alternate gene names: 119357470

Gene position: 1897022-1898284 (Clockwise)

Preceding gene: 119357469

Following gene: 119357472

Centisome position: 60.53

GC content: 48.14

Gene sequence:

>1263_bases
ATGCACTGCGTTATGAATGAAAAAGGCATGAGTTTACGTGACCTCCTTTCACAGGCGATCTACTCACTGGTCGCAAACAA
GCTCCGCTCCCTGTTGACAACAATGGGCGTTGCGGTTGGCGTGTTTTCGATTATTGCAGTCATGACCGCTCTCCAGGCCA
TCGAACAAAGCGTGGAATCAGGCTTGACCAGTCTTGGTGCAAACACCTTCCAGATCCAGAAACTTCCAGCGACCTTTTTT
GGCGGCGGGCACTCCAGAAGTCTCTATGCCAACAGAAAAGACATCTCCTACAAAGAGGGCTTGATGTTCAGAAAACTCAT
GGAATCAAGAACTAAAACCATAGGGTTCATGATCTCAAGCCAGGCAAAACAGGCAAAATATGCCAACCGTTTCACAAACC
CCGATGTCATTCTGACCGGAGCTGACGATCACTTTGCGATTGCAAACGGCTACGGCATCCGCCTGGGAAGAAACTTCAAT
AACAGCGACATCCAGTATGCCCGAAATTTCGCACTGCTTGGCAGTGAAGTCTCTGAATCACTCTTTCCTGCCACAGAAAA
TCCTCTTCACAAATCAATCAAAATAAACGGAGAGGTCTTCACCGTTGCAGGTGTTTTTGAAAAAAAAGGCGCCGCTTTCG
GCCAGAGTCAGGACAATCTGGTATTGATCCCCATTACCCGGTACCTTGATCATATCAACGAACAAAGCAGCCTGAACATA
ACCATCGAAGCGATCTCGCAGAAACAGTACAAGGAAACCATCGACCAGTCGATCGGAGCCATGAGAATCGCACGCGGGCT
CACCGTAAAAGAGCCCAATGATTTTGAAATCAGAACCAATGAGTCTCTGATTGATTCGTTCCGGGATATTCAGCGGGCAA
TAACCACCGGTGCATTTATTATCAGCTTTATGGCGCTTCTTTCCTCCGGGGTTGGAATCATGAATATCATGCTGGTCAGC
GTTACTGAACGAACAAAAGAGATCGGCATCCGAAAATCCCTTGGAGCGCCACAACAGAGCATCCTGCGACAATTCCTGCT
TGAAGCAGTCATTCTCTCCGTAGCCGGCGGTCTTATCGGCATTATCACCGGCGTCAGCGCGGGAAATATTGTTGCCCTCA
AGTTTAATCTGAACGCAATATTTCCATGGCTGTGGATATTCATTGCCATGGCAGTCTGCTCGATTATTGGAGTGACCTTC
GGACTTTTACCCGCATGGAAAGCCGCAATGCTTGACCCTGTTGAAGCACTTCATCCGAAATAG

Upstream 100 bases:

>100_bases
TCACCTGATCTTGTCATGGCAAGTATCGCGGTATCCCTTATCACCGGCATTATCTCTGGTCTTGCTCCTGCCGTAACGGC
ATCACGGCTTGAGGCTGCAG

Downstream 100 bases:

>100_bases
CCCTATCCCACAACGGTTCAGGCAAAAGAGACAATACGATACAAGTTCTCAGCAAACCGTTTGACATCATGGATCAATGC
CGGCTCACAGGCCGCAAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MHCVMNEKGMSLRDLLSQAIYSLVANKLRSLLTTMGVAVGVFSIIAVMTALQAIEQSVESGLTSLGANTFQIQKLPATFF
GGGHSRSLYANRKDISYKEGLMFRKLMESRTKTIGFMISSQAKQAKYANRFTNPDVILTGADDHFAIANGYGIRLGRNFN
NSDIQYARNFALLGSEVSESLFPATENPLHKSIKINGEVFTVAGVFEKKGAAFGQSQDNLVLIPITRYLDHINEQSSLNI
TIEAISQKQYKETIDQSIGAMRIARGLTVKEPNDFEIRTNESLIDSFRDIQRAITTGAFIISFMALLSSGVGIMNIMLVS
VTERTKEIGIRKSLGAPQQSILRQFLLEAVILSVAGGLIGIITGVSAGNIVALKFNLNAIFPWLWIFIAMAVCSIIGVTF
GLLPAWKAAMLDPVEALHPK

Sequences:

>Translated_420_residues
MHCVMNEKGMSLRDLLSQAIYSLVANKLRSLLTTMGVAVGVFSIIAVMTALQAIEQSVESGLTSLGANTFQIQKLPATFF
GGGHSRSLYANRKDISYKEGLMFRKLMESRTKTIGFMISSQAKQAKYANRFTNPDVILTGADDHFAIANGYGIRLGRNFN
NSDIQYARNFALLGSEVSESLFPATENPLHKSIKINGEVFTVAGVFEKKGAAFGQSQDNLVLIPITRYLDHINEQSSLNI
TIEAISQKQYKETIDQSIGAMRIARGLTVKEPNDFEIRTNESLIDSFRDIQRAITTGAFIISFMALLSSGVGIMNIMLVS
VTERTKEIGIRKSLGAPQQSILRQFLLEAVILSVAGGLIGIITGVSAGNIVALKFNLNAIFPWLWIFIAMAVCSIIGVTF
GLLPAWKAAMLDPVEALHPK
>Mature_420_residues
MHCVMNEKGMSLRDLLSQAIYSLVANKLRSLLTTMGVAVGVFSIIAVMTALQAIEQSVESGLTSLGANTFQIQKLPATFF
GGGHSRSLYANRKDISYKEGLMFRKLMESRTKTIGFMISSQAKQAKYANRFTNPDVILTGADDHFAIANGYGIRLGRNFN
NSDIQYARNFALLGSEVSESLFPATENPLHKSIKINGEVFTVAGVFEKKGAAFGQSQDNLVLIPITRYLDHINEQSSLNI
TIEAISQKQYKETIDQSIGAMRIARGLTVKEPNDFEIRTNESLIDSFRDIQRAITTGAFIISFMALLSSGVGIMNIMLVS
VTERTKEIGIRKSLGAPQQSILRQFLLEAVILSVAGGLIGIITGVSAGNIVALKFNLNAIFPWLWIFIAMAVCSIIGVTF
GLLPAWKAAMLDPVEALHPK

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=416, Percent_Identity=29.8076923076923, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45895; Mature: 45895

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCVMNEKGMSLRDLLSQAIYSLVANKLRSLLTTMGVAVGVFSIIAVMTALQAIEQSVES
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTSLGANTFQIQKLPATFFGGGHSRSLYANRKDISYKEGLMFRKLMESRTKTIGFMISS
HHHHHCCCCEEEEECCHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAKQAKYANRFTNPDVILTGADDHFAIANGYGIRLGRNFNNSDIQYARNFALLGSEVSES
HHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LFPATENPLHKSIKINGEVFTVAGVFEKKGAAFGQSQDNLVLIPITRYLDHINEQSSLNI
HCCCCCCCCCCEEEECCEEEEEEEHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCEE
TIEAISQKQYKETIDQSIGAMRIARGLTVKEPNDFEIRTNESLIDSFRDIQRAITTGAFI
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
ISFMALLSSGVGIMNIMLVSVTERTKEIGIRKSLGAPQQSILRQFLLEAVILSVAGGLIG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHH
IITGVSAGNIVALKFNLNAIFPWLWIFIAMAVCSIIGVTFGLLPAWKAAMLDPVEALHPK
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC
>Mature Secondary Structure
MHCVMNEKGMSLRDLLSQAIYSLVANKLRSLLTTMGVAVGVFSIIAVMTALQAIEQSVES
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLTSLGANTFQIQKLPATFFGGGHSRSLYANRKDISYKEGLMFRKLMESRTKTIGFMISS
HHHHHCCCCEEEEECCHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QAKQAKYANRFTNPDVILTGADDHFAIANGYGIRLGRNFNNSDIQYARNFALLGSEVSES
HHHHHHHHHCCCCCCEEEECCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHH
LFPATENPLHKSIKINGEVFTVAGVFEKKGAAFGQSQDNLVLIPITRYLDHINEQSSLNI
HCCCCCCCCCCEEEECCEEEEEEEHHHHCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCEE
TIEAISQKQYKETIDQSIGAMRIARGLTVKEPNDFEIRTNESLIDSFRDIQRAITTGAFI
EEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHH
ISFMALLSSGVGIMNIMLVSVTERTKEIGIRKSLGAPQQSILRQFLLEAVILSVAGGLIG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHCHHHH
IITGVSAGNIVALKFNLNAIFPWLWIFIAMAVCSIIGVTFGLLPAWKAAMLDPVEALHPK
HHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA