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The map label for this gene is macB [H]

Identifier: 119357469

GI number: 119357469

Start: 1895776

End: 1897041

Strand: Direct

Name: macB [H]

Synonym: Cpha266_1668

Alternate gene names: 119357469

Gene position: 1895776-1897041 (Clockwise)

Preceding gene: 119357468

Following gene: 119357470

Centisome position: 60.49

GC content: 48.34

Gene sequence:

>1266_bases
ATGAAACCAGCCCGGCAGCAGTTTCGAAATGAAACCATGGAGAGCCTGAACATTGCGGTGTTTCAGATCAAATCCAATAA
ATTCCGGTCCTTTCTCACGGCTCTCGGCGTTATTATCGGCATTGTTGCCATCACCATGATGGGTACGGCAATAAACGGTA
TTGACACCGGATTTGAAAAAAGCCTGGCCATGCTTGGCTACGATGTCGTCTACGTCCAGAAATCCTCATGGAGCACCATG
GGCCAATGGTGGCGTTACAGAAACCGTCCTGACCTCAAAACCGACTATGCGACACAGATCAATCGTATTATTGCCGACAA
TCCGGATTCCGAACTCGAGATAGCCGTTCCCCAGATGTCAACCTACCAGGCTTCGGCAAAATACAGGGAAAAAATTCTTG
AATCGATCTTTTCCCTTGGCACAACCCATGACTACCTTCTGACGGCATCGGGAGATCTTGCTCAAGGCCGATTCTTTACT
CCGCAGGAATCGGCCGGGGGAAACATGGTCTGTGTCATAGGCGATGACATCGCAACAGGACTGTTCCCCCAGGAAAACGC
TCTGGGCAAAACGATTCAGATCAAAAACGGAAAGTTCAGAATTATCGGCATTTTTAAAAAACAGGGGAAATTTCTCGGGC
TCTTCAGTTTTGACAATCAGGCCATCATGCCCCTTGCCGCCTTTGAAAAAGTATATGGACGAAATATGTTTGTAACCATC
CGGGTCAAGATCAGGAATCAGACCCGCATTGCTGCAGCAGAAGAGGAGTTGCGCGGACTCATGAGAAGAATACGACGCCT
TCCTGTCGGCAGGGAGGATGATTTTTCGATAAATGAACAAAAAGCCTTTAAAAGCCAGCTTGATCCAATCAAGAACGGCA
TTGCTGCGGCAGGCATCTTCATTACAGGCATGTCGCTTTTTGTCGGCGCAATCGGGATCATGAACATAACGTTTGTCAGC
GTCAAGGAACGCACGCGGGAAATTGGCTTGCGCAAAGCACTTGGAGCCAGAAGGCGCACCATTCTCATGCAGTTTCTCAT
TGAATCGGTAATGATCTGTATGCTTGGAGGAGTGATCGGGTTGTTTACAGCACTAAGCATTACCTTTGCGCTTCGACTTA
TTGTGCCTGATTTTCCCGTAAAGTTTTCACCTGATCTTGTCATGGCAAGTATCGCGGTATCCCTTATCACCGGCATTATC
TCTGGTCTTGCTCCTGCCGTAACGGCATCACGGCTTGAGGCTGCAGATGCACTGCGTTATGAATGA

Upstream 100 bases:

>100_bases
GCAACACGATTATCCTTATTACGCATGAAGAGGATATCGCCCGCTATACCCACCGCGTCATACGGCTGAGAGATGGAAAA
ATTGAAAGCGACATACCGCA

Downstream 100 bases:

>100_bases
AAAAGGCATGAGTTTACGTGACCTCCTTTCACAGGCGATCTACTCACTGGTCGCAAACAAGCTCCGCTCCCTGTTGACAA
CAATGGGCGTTGCGGTTGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKPARQQFRNETMESLNIAVFQIKSNKFRSFLTALGVIIGIVAITMMGTAINGIDTGFEKSLAMLGYDVVYVQKSSWSTM
GQWWRYRNRPDLKTDYATQINRIIADNPDSELEIAVPQMSTYQASAKYREKILESIFSLGTTHDYLLTASGDLAQGRFFT
PQESAGGNMVCVIGDDIATGLFPQENALGKTIQIKNGKFRIIGIFKKQGKFLGLFSFDNQAIMPLAAFEKVYGRNMFVTI
RVKIRNQTRIAAAEEELRGLMRRIRRLPVGREDDFSINEQKAFKSQLDPIKNGIAAAGIFITGMSLFVGAIGIMNITFVS
VKERTREIGLRKALGARRRTILMQFLIESVMICMLGGVIGLFTALSITFALRLIVPDFPVKFSPDLVMASIAVSLITGII
SGLAPAVTASRLEAADALRYE

Sequences:

>Translated_421_residues
MKPARQQFRNETMESLNIAVFQIKSNKFRSFLTALGVIIGIVAITMMGTAINGIDTGFEKSLAMLGYDVVYVQKSSWSTM
GQWWRYRNRPDLKTDYATQINRIIADNPDSELEIAVPQMSTYQASAKYREKILESIFSLGTTHDYLLTASGDLAQGRFFT
PQESAGGNMVCVIGDDIATGLFPQENALGKTIQIKNGKFRIIGIFKKQGKFLGLFSFDNQAIMPLAAFEKVYGRNMFVTI
RVKIRNQTRIAAAEEELRGLMRRIRRLPVGREDDFSINEQKAFKSQLDPIKNGIAAAGIFITGMSLFVGAIGIMNITFVS
VKERTREIGLRKALGARRRTILMQFLIESVMICMLGGVIGLFTALSITFALRLIVPDFPVKFSPDLVMASIAVSLITGII
SGLAPAVTASRLEAADALRYE
>Mature_421_residues
MKPARQQFRNETMESLNIAVFQIKSNKFRSFLTALGVIIGIVAITMMGTAINGIDTGFEKSLAMLGYDVVYVQKSSWSTM
GQWWRYRNRPDLKTDYATQINRIIADNPDSELEIAVPQMSTYQASAKYREKILESIFSLGTTHDYLLTASGDLAQGRFFT
PQESAGGNMVCVIGDDIATGLFPQENALGKTIQIKNGKFRIIGIFKKQGKFLGLFSFDNQAIMPLAAFEKVYGRNMFVTI
RVKIRNQTRIAAAEEELRGLMRRIRRLPVGREDDFSINEQKAFKSQLDPIKNGIAAAGIFITGMSLFVGAIGIMNITFVS
VKERTREIGLRKALGARRRTILMQFLIESVMICMLGGVIGLFTALSITFALRLIVPDFPVKFSPDLVMASIAVSLITGII
SGLAPAVTASRLEAADALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=422, Percent_Identity=28.9099526066351, Blast_Score=152, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46678; Mature: 46678

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPARQQFRNETMESLNIAVFQIKSNKFRSFLTALGVIIGIVAITMMGTAINGIDTGFEK
CCCHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SLAMLGYDVVYVQKSSWSTMGQWWRYRNRPDLKTDYATQINRIIADNPDSELEIAVPQMS
HHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
TYQASAKYREKILESIFSLGTTHDYLLTASGDLAQGRFFTPQESAGGNMVCVIGDDIATG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCHHHC
LFPQENALGKTIQIKNGKFRIIGIFKKQGKFLGLFSFDNQAIMPLAAFEKVYGRNMFVTI
CCCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEE
RVKIRNQTRIAAAEEELRGLMRRIRRLPVGREDDFSINEQKAFKSQLDPIKNGIAAAGIF
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ITGMSLFVGAIGIMNITFVSVKERTREIGLRKALGARRRTILMQFLIESVMICMLGGVIG
HHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFTALSITFALRLIVPDFPVKFSPDLVMASIAVSLITGIISGLAPAVTASRLEAADALRY
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
E
C
>Mature Secondary Structure
MKPARQQFRNETMESLNIAVFQIKSNKFRSFLTALGVIIGIVAITMMGTAINGIDTGFEK
CCCHHHHHHHHHHHHCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SLAMLGYDVVYVQKSSWSTMGQWWRYRNRPDLKTDYATQINRIIADNPDSELEIAVPQMS
HHHHHCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCH
TYQASAKYREKILESIFSLGTTHDYLLTASGDLAQGRFFTPQESAGGNMVCVIGDDIATG
HHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCHHHC
LFPQENALGKTIQIKNGKFRIIGIFKKQGKFLGLFSFDNQAIMPLAAFEKVYGRNMFVTI
CCCCCCCCCCEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEE
RVKIRNQTRIAAAEEELRGLMRRIRRLPVGREDDFSINEQKAFKSQLDPIKNGIAAAGIF
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ITGMSLFVGAIGIMNITFVSVKERTREIGLRKALGARRRTILMQFLIESVMICMLGGVIG
HHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFTALSITFALRLIVPDFPVKFSPDLVMASIAVSLITGIISGLAPAVTASRLEAADALRY
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA