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The map label for this gene is argG [H]

Identifier: 119357136

GI number: 119357136

Start: 1517270

End: 1518472

Strand: Direct

Name: argG [H]

Synonym: Cpha266_1325

Alternate gene names: 119357136

Gene position: 1517270-1518472 (Clockwise)

Preceding gene: 119357135

Following gene: 119357138

Centisome position: 48.41

GC content: 54.61

Gene sequence:

>1203_bases
ATGAGCAAGGAAAAAATCGCCATAGCCTATTCCGGCGGACTTGATACCTCTATCATGATCAAATGGCTTAAAGACAAATA
CGATGCCGAGATCGTTGCCGTTACCGGCAACCTCGGCCAGCAGAAAGAGATCGAAAACCTCGAATCAAAAGCAATAGCCA
CCGGAGCATCGGCATTTCAGTTTGTCGATCTCCGCAAAGAGTTTGTCGAAGAGTACATCTGGAAAGCCCTCAAGGCCGGA
GCCCTCTATGAAGATGTCTACCCCCTGGCAACAGCCCTCGGCCGTCCGCTGCTGGCCAAAGCCATTGTCGATGCCGCACT
TGCCGAAGGGTGCACCATGCTGGCACACGGCTGTACCGGCAAAGGAAACGACCAGGTTCGATTTGAGGTAACCTTTGCCT
CGCTTGCGCCGCATCTCAAAGTGCTTGCTCCGCTACGCGAATGGGAGTTCACCTCGCGTGAGGCAGAGATAGCCTACGCG
CTCGAACACAACATCCCGGTTTCGGCAACAAAGAAAAGCCCCTACTCGATCGACGAGAACATCTGGGGAATCAGCATCGA
GTGCGGCGTGCTTGAAGATCCGATGGTTGCGCCTCCCGAAGATGCCTACCAGATCACCACCTCGCCTGAAAACGCACCTG
ACCGCCCCACCGTTGTGGATATCGAGTTTGTGCAGGGCGTGCCTGTTTCGCTTGACGGAAAAACGATGAGCGGGCTTGAA
CTGATCATGAAACTCAACGAAACCGGAGCCGCAAACGGCGTCGGAAGACTTGATATGATCGAGAACCGCGTTGTCGGCAT
CAAATCGCGCGAGATCTACGAAGCGCCGGCAGCAACAATCCTGCACTTCGCGCACCGCGAACTCGAACGGCTCACGCTTG
AAAAAACCGTTTTCCAGTACAAAAAGAACATCAGCCAGGACTACGCAAACATCATCTATAACGGACTCTGGTTCTCCCCC
ATGCGCCACGCGCTTGACGCCTTTATCGAAGAAACCCAGAAACCGGTAACCGGTCTGGTACGGGTAAAACTCTACAAGGG
GTCGCTTTCGCTGCTCGGCAGAACATCGCCCAACTCGCTCTACAACGAGGAACTGGCAACCTACACCGAAGCCGACACCT
TCAACCACAAAGCCGCCGCCGGGTTTATCCATCTCTACGGCCTTGGCCTGAAAACCTTCAGCGAAGTCAACCCCGCCCGA
TAA

Upstream 100 bases:

>100_bases
CGACACGGTTCTGGTCATTCCCGGTTCGATAAAGCAGATTTCAGAGCTTGTAAGCTATATTAAGGATAATCTTTCACAAA
ACGCATAATCATAAACCCGT

Downstream 100 bases:

>100_bases
CCCTCATCCGTCACTCACTGCGCAGGTCACGTTTTCACCGACCTGCGCATGGCTGGCGCCGGATTGACACAGCAATTGGT
TAAAAGGGGGTAATGGTTAC

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSKEKIAIAYSGGLDTSIMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAIATGASAFQFVDLRKEFVEEYIWKALKAG
ALYEDVYPLATALGRPLLAKAIVDAALAEGCTMLAHGCTGKGNDQVRFEVTFASLAPHLKVLAPLREWEFTSREAEIAYA
LEHNIPVSATKKSPYSIDENIWGISIECGVLEDPMVAPPEDAYQITTSPENAPDRPTVVDIEFVQGVPVSLDGKTMSGLE
LIMKLNETGAANGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQYKKNISQDYANIIYNGLWFSP
MRHALDAFIEETQKPVTGLVRVKLYKGSLSLLGRTSPNSLYNEELATYTEADTFNHKAAAGFIHLYGLGLKTFSEVNPAR

Sequences:

>Translated_400_residues
MSKEKIAIAYSGGLDTSIMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAIATGASAFQFVDLRKEFVEEYIWKALKAG
ALYEDVYPLATALGRPLLAKAIVDAALAEGCTMLAHGCTGKGNDQVRFEVTFASLAPHLKVLAPLREWEFTSREAEIAYA
LEHNIPVSATKKSPYSIDENIWGISIECGVLEDPMVAPPEDAYQITTSPENAPDRPTVVDIEFVQGVPVSLDGKTMSGLE
LIMKLNETGAANGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQYKKNISQDYANIIYNGLWFSP
MRHALDAFIEETQKPVTGLVRVKLYKGSLSLLGRTSPNSLYNEELATYTEADTFNHKAAAGFIHLYGLGLKTFSEVNPAR
>Mature_399_residues
SKEKIAIAYSGGLDTSIMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAIATGASAFQFVDLRKEFVEEYIWKALKAGA
LYEDVYPLATALGRPLLAKAIVDAALAEGCTMLAHGCTGKGNDQVRFEVTFASLAPHLKVLAPLREWEFTSREAEIAYAL
EHNIPVSATKKSPYSIDENIWGISIECGVLEDPMVAPPEDAYQITTSPENAPDRPTVVDIEFVQGVPVSLDGKTMSGLEL
IMKLNETGAANGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQYKKNISQDYANIIYNGLWFSPM
RHALDAFIEETQKPVTGLVRVKLYKGSLSLLGRTSPNSLYNEELATYTEADTFNHKAAAGFIHLYGLGLKTFSEVNPAR

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=406, Percent_Identity=43.5960591133005, Blast_Score=330, Evalue=2e-90,
Organism=Homo sapiens, GI16950633, Length=406, Percent_Identity=43.5960591133005, Blast_Score=330, Evalue=2e-90,
Organism=Escherichia coli, GI1789563, Length=390, Percent_Identity=31.2820512820513, Blast_Score=148, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6324514, Length=410, Percent_Identity=41.219512195122, Blast_Score=322, Evalue=6e-89,
Organism=Drosophila melanogaster, GI21358151, Length=404, Percent_Identity=40.3465346534653, Blast_Score=300, Evalue=1e-81,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 44154; Mature: 44023

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEKIAIAYSGGLDTSIMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAIATGASAFQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHH
FVDLRKEFVEEYIWKALKAGALYEDVYPLATALGRPLLAKAIVDAALAEGCTMLAHGCTG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCC
KGNDQVRFEVTFASLAPHLKVLAPLREWEFTSREAEIAYALEHNIPVSATKKSPYSIDEN
CCCCEEEEEEEHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCC
IWGISIECGVLEDPMVAPPEDAYQITTSPENAPDRPTVVDIEFVQGVPVSLDGKTMSGLE
EEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHH
LIMKLNETGAANGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQY
HHHHHCCCCCCCCCCCHHHHHCCEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
KKNISQDYANIIYNGLWFSPMRHALDAFIEETQKPVTGLVRVKLYKGSLSLLGRTSPNSL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEECCCCCHH
YNEELATYTEADTFNHKAAAGFIHLYGLGLKTFSEVNPAR
HHHHHHHHHCCCCCCCHHHHCEEEEEECCHHHHCCCCCCC
>Mature Secondary Structure 
SKEKIAIAYSGGLDTSIMIKWLKDKYDAEIVAVTGNLGQQKEIENLESKAIATGASAFQ
CCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHH
FVDLRKEFVEEYIWKALKAGALYEDVYPLATALGRPLLAKAIVDAALAEGCTMLAHGCTG
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECCCCC
KGNDQVRFEVTFASLAPHLKVLAPLREWEFTSREAEIAYALEHNIPVSATKKSPYSIDEN
CCCCEEEEEEEHHHHCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCEECCCCCCCCCCC
IWGISIECGVLEDPMVAPPEDAYQITTSPENAPDRPTVVDIEFVQGVPVSLDGKTMSGLE
EEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCEEECCCCHHHHH
LIMKLNETGAANGVGRLDMIENRVVGIKSREIYEAPAATILHFAHRELERLTLEKTVFQY
HHHHHCCCCCCCCCCCHHHHHCCEEECCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
KKNISQDYANIIYNGLWFSPMRHALDAFIEETQKPVTGLVRVKLYKGSLSLLGRTSPNSL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCEEEEECCCCCHH
YNEELATYTEADTFNHKAAAGFIHLYGLGLKTFSEVNPAR
HHHHHHHHHCCCCCCCHHHHCEEEEEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA