Click here to switch to the map view.

The map label for this gene is htpG

Identifier: 119357004

GI number: 119357004

Start: 1341100

End: 1342980

Strand: Direct

Name: htpG

Synonym: Cpha266_1188

Alternate gene names: 119357004

Gene position: 1341100-1342980 (Clockwise)

Preceding gene: 119357003

Following gene: 119357005

Centisome position: 42.79

GC content: 47.05

Gene sequence:

>1881_bases
ATGACCAACAATGATACTCCGGGAATGCGGGAATATGAATACAAGGCTGAAATGAAACAGCTTCTTGAGCTGATTGTTCA
TTCTCTTTATACCCATCCCGAAATTTTTCTCAGAGAGCTGATTTCCAATGCTTCCGATGCGTTAAGCAAAGTTCGCTTTA
ATGCTCTGACCGATGAGTCAATCATAAACAGTGATGCCGGACTTGCCATCAGAATCACCCTCGATCCTGAAGCTCATACC
ATTGTTATTGAGGATAACGGTACGGGAATGACTGAAGAGGAGTTGATTTTAAATCTCGGAACGGTTGCCCGTTCAGGAAC
ACTCGGTTTCCTGCAGGCCCTCAAGGAGCAGCAGAAAGAGCTTGACGGCAATCTTATCGGACAGTTCGGCGTGGGATTTT
ATTCGGTATTTATGGTAACCGACGAGGTCACTGTTGAAACCAGAAGTTCAGGAGCGGATTCTGCAGGGTATCGCTGGCGT
TCCGGCGCTGCGGGTACCTTTACCATTGAGAGAATCGAAAAAGAGCAGCGCGGCACGAAGATCTCTTTTGCACTGAAGGA
TGAGTTCAAGGAGTTTTCCGAAGCCTACCGGATCGAACAGATAATCAGGAAATACTCTAATTTTGTCGATTTCCCGATTT
TTCTCGGTGATAATCAGATCAATACCATCTCTGCGCTCTGGCAGCGTTCGAAAAACGAGGTGAGCGATGAGGAACGTAAT
GAATTTTACAAGTTTCTCTCCAATGACTTTAATCCTCCGCTTGACTCACTGCATCTGTCAGTTGAGGGAAAAGTCTGCTT
CAAGGCTCTTCTGTTTCTGCCCGAAGAGGCTCCTCCGGAACTTATGTACCGTCAGGGCGATCTCGAAAGCCGCGGTCCGC
AGCTTTATGTGAAAAAGGTGCTGATTCAGCAGGAGTGCCGTGATCTTCTGCCCGAGTATCTGAGATTTGTGGCAGGTGTT
GTCGACACCGAAGATCTTCCGCTCAACGTATCTCGCGAAGTGGTTCAGTCAAGCAAGGTTATGGCAAACATCCGCCAGAT
TCTTACCGGAAAAATTCTTTCGTGGTTTGAATCGATGGCGACAGATCAGCCTGAGAAATTCCGCAAGTTTTACAAGGCGT
TCGGTCCTTTTCTGAAAATCGGACTCAATACCGATTTCACTCATCGCGACAGGATTATCGGGCTCATGCGTTTTGAGAGC
ACCAAAACAGCGGAAGGCGAGTATGTTACCTTCAAAGAGTATGTGGAACGTATGGAGGCCGGGCAAAACGAGATCTACTA
TCACAGCGGCAGCAACCGCATTCAGCTTCTTGCCCATCCCAACCTTGAATATTTCCAGCACAAGGGTATAGAGGTTCTTC
TGTTGAGCGATCCCGTTGATGTTTTTGTTATTCCTTCTATTCATGAGTATGATAAAAAGCCGCTCAAATCCATTGAGAAA
GCAGATATTGACTTCACCCGGACAGGCGATGACAAAACGGAGCCCCCGCTTCCCGAAACGCTCTCTCAGCCGCTGCTTGG
TCTGTTCCGACAGACGATAGGAGATGTCATTGAAGATGTCGTAGAGTCGCATCGTCTTGTCAGCTCTCCGGTTACACTGG
TTTCCGGTAAGGATAGTCTCGACAGCAGTATGGAAAAGATGATGAAAATGATGCATGCGGAGATGCCTGCTGCAAAAAAG
ATACTCGAAGTCAATACTTCACATCCGATTATCAAAAATCTTTCAGGGATGATTATGGCCAATGAGCATAATCCGCTTAT
CAGAACGGTCATTCAGCAGTTGTATGATGGAGCGCTTCTGCATGAAGGCAACCTTGATGCGACCACAGGGTTTCTTCAGA
GAATGAATGAACTGATCGAGGCTGCAACGATGAGCCGATAA

Upstream 100 bases:

>100_bases
TAATCGAGGTTTCTTTCATCACTACGTTTCGCTCAGTTTTTTTCTGCCCGAAGGGATGATTCTTCGGGCCTCTTAATCAA
ACCTAACAAGGTGTTTTCTT

Downstream 100 bases:

>100_bases
TTGAAATGCCGATAACCCAATAACTTTTTAACCTGGAACCGTTGTGAAACAGAGCAGGGATTTTGATGCGAGGCAGGTTG
TTGCTTTTCAGAAAAACGAG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 626; Mature: 625

Protein sequence:

>626_residues
MTNNDTPGMREYEYKAEMKQLLELIVHSLYTHPEIFLRELISNASDALSKVRFNALTDESIINSDAGLAIRITLDPEAHT
IVIEDNGTGMTEEELILNLGTVARSGTLGFLQALKEQQKELDGNLIGQFGVGFYSVFMVTDEVTVETRSSGADSAGYRWR
SGAAGTFTIERIEKEQRGTKISFALKDEFKEFSEAYRIEQIIRKYSNFVDFPIFLGDNQINTISALWQRSKNEVSDEERN
EFYKFLSNDFNPPLDSLHLSVEGKVCFKALLFLPEEAPPELMYRQGDLESRGPQLYVKKVLIQQECRDLLPEYLRFVAGV
VDTEDLPLNVSREVVQSSKVMANIRQILTGKILSWFESMATDQPEKFRKFYKAFGPFLKIGLNTDFTHRDRIIGLMRFES
TKTAEGEYVTFKEYVERMEAGQNEIYYHSGSNRIQLLAHPNLEYFQHKGIEVLLLSDPVDVFVIPSIHEYDKKPLKSIEK
ADIDFTRTGDDKTEPPLPETLSQPLLGLFRQTIGDVIEDVVESHRLVSSPVTLVSGKDSLDSSMEKMMKMMHAEMPAAKK
ILEVNTSHPIIKNLSGMIMANEHNPLIRTVIQQLYDGALLHEGNLDATTGFLQRMNELIEAATMSR

Sequences:

>Translated_626_residues
MTNNDTPGMREYEYKAEMKQLLELIVHSLYTHPEIFLRELISNASDALSKVRFNALTDESIINSDAGLAIRITLDPEAHT
IVIEDNGTGMTEEELILNLGTVARSGTLGFLQALKEQQKELDGNLIGQFGVGFYSVFMVTDEVTVETRSSGADSAGYRWR
SGAAGTFTIERIEKEQRGTKISFALKDEFKEFSEAYRIEQIIRKYSNFVDFPIFLGDNQINTISALWQRSKNEVSDEERN
EFYKFLSNDFNPPLDSLHLSVEGKVCFKALLFLPEEAPPELMYRQGDLESRGPQLYVKKVLIQQECRDLLPEYLRFVAGV
VDTEDLPLNVSREVVQSSKVMANIRQILTGKILSWFESMATDQPEKFRKFYKAFGPFLKIGLNTDFTHRDRIIGLMRFES
TKTAEGEYVTFKEYVERMEAGQNEIYYHSGSNRIQLLAHPNLEYFQHKGIEVLLLSDPVDVFVIPSIHEYDKKPLKSIEK
ADIDFTRTGDDKTEPPLPETLSQPLLGLFRQTIGDVIEDVVESHRLVSSPVTLVSGKDSLDSSMEKMMKMMHAEMPAAKK
ILEVNTSHPIIKNLSGMIMANEHNPLIRTVIQQLYDGALLHEGNLDATTGFLQRMNELIEAATMSR
>Mature_625_residues
TNNDTPGMREYEYKAEMKQLLELIVHSLYTHPEIFLRELISNASDALSKVRFNALTDESIINSDAGLAIRITLDPEAHTI
VIEDNGTGMTEEELILNLGTVARSGTLGFLQALKEQQKELDGNLIGQFGVGFYSVFMVTDEVTVETRSSGADSAGYRWRS
GAAGTFTIERIEKEQRGTKISFALKDEFKEFSEAYRIEQIIRKYSNFVDFPIFLGDNQINTISALWQRSKNEVSDEERNE
FYKFLSNDFNPPLDSLHLSVEGKVCFKALLFLPEEAPPELMYRQGDLESRGPQLYVKKVLIQQECRDLLPEYLRFVAGVV
DTEDLPLNVSREVVQSSKVMANIRQILTGKILSWFESMATDQPEKFRKFYKAFGPFLKIGLNTDFTHRDRIIGLMRFEST
KTAEGEYVTFKEYVERMEAGQNEIYYHSGSNRIQLLAHPNLEYFQHKGIEVLLLSDPVDVFVIPSIHEYDKKPLKSIEKA
DIDFTRTGDDKTEPPLPETLSQPLLGLFRQTIGDVIEDVVESHRLVSSPVTLVSGKDSLDSSMEKMMKMMHAEMPAAKKI
LEVNTSHPIIKNLSGMIMANEHNPLIRTVIQQLYDGALLHEGNLDATTGFLQRMNELIEAATMSR

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=623, Percent_Identity=35.3130016051364, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI4507677, Length=659, Percent_Identity=33.6874051593323, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI20149594, Length=396, Percent_Identity=33.8383838383838, Blast_Score=246, Evalue=5e-65,
Organism=Homo sapiens, GI154146191, Length=396, Percent_Identity=33.5858585858586, Blast_Score=239, Evalue=8e-63,
Organism=Homo sapiens, GI153792590, Length=396, Percent_Identity=33.5858585858586, Blast_Score=236, Evalue=5e-62,
Organism=Escherichia coli, GI1786679, Length=622, Percent_Identity=39.3890675241158, Blast_Score=460, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17559162, Length=648, Percent_Identity=35.6481481481481, Blast_Score=408, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17542208, Length=666, Percent_Identity=34.2342342342342, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI115535205, Length=629, Percent_Identity=33.3863275039746, Blast_Score=340, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=35.6979405034325, Blast_Score=271, Evalue=7e-73,
Organism=Saccharomyces cerevisiae, GI6325016, Length=409, Percent_Identity=35.4523227383863, Blast_Score=254, Evalue=4e-68,
Organism=Saccharomyces cerevisiae, GI6323840, Length=409, Percent_Identity=34.9633251833741, Blast_Score=249, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24586016, Length=639, Percent_Identity=35.8372456964006, Blast_Score=380, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21357739, Length=679, Percent_Identity=33.8733431516937, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI17647529, Length=414, Percent_Identity=32.8502415458937, Blast_Score=246, Evalue=3e-65,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_CHLPD (A1BFP7)

Other databases:

- EMBL:   CP000492
- RefSeq:   YP_911648.1
- ProteinModelPortal:   A1BFP7
- STRING:   A1BFP7
- GeneID:   4569946
- GenomeReviews:   CP000492_GR
- KEGG:   cph:Cpha266_1188
- NMPDR:   fig|290317.7.peg.1261
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71108; Mature: 70977

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNDTPGMREYEYKAEMKQLLELIVHSLYTHPEIFLRELISNASDALSKVRFNALTDES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IINSDAGLAIRITLDPEAHTIVIEDNGTGMTEEELILNLGTVARSGTLGFLQALKEQQKE
HHCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LDGNLIGQFGVGFYSVFMVTDEVTVETRSSGADSAGYRWRSGAAGTFTIERIEKEQRGTK
CCCCEEHHHHHHHEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
ISFALKDEFKEFSEAYRIEQIIRKYSNFVDFPIFLGDNQINTISALWQRSKNEVSDEERN
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHH
EFYKFLSNDFNPPLDSLHLSVEGKVCFKALLFLPEEAPPELMYRQGDLESRGPQLYVKKV
HHHHHHHCCCCCCHHHEEEEECHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHH
LIQQECRDLLPEYLRFVAGVVDTEDLPLNVSREVVQSSKVMANIRQILTGKILSWFESMA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDQPEKFRKFYKAFGPFLKIGLNTDFTHRDRIIGLMRFESTKTAEGEYVTFKEYVERMEA
CCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHEEEEEECCCCCCCCCEEEHHHHHHHHHC
GQNEIYYHSGSNRIQLLAHPNLEYFQHKGIEVLLLSDPVDVFVIPSIHEYDKKPLKSIEK
CCCEEEEECCCCEEEEEECCCHHHHHCCCCEEEEEECCCCEEEECCHHHHCHHHHHHHHH
ADIDFTRTGDDKTEPPLPETLSQPLLGLFRQTIGDVIEDVVESHRLVSSPVTLVSGKDSL
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHH
DSSMEKMMKMMHAEMPAAKKILEVNTSHPIIKNLSGMIMANEHNPLIRTVIQQLYDGALL
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHCCCEE
HEGNLDATTGFLQRMNELIEAATMSR
ECCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNNDTPGMREYEYKAEMKQLLELIVHSLYTHPEIFLRELISNASDALSKVRFNALTDES
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
IINSDAGLAIRITLDPEAHTIVIEDNGTGMTEEELILNLGTVARSGTLGFLQALKEQQKE
HHCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LDGNLIGQFGVGFYSVFMVTDEVTVETRSSGADSAGYRWRSGAAGTFTIERIEKEQRGTK
CCCCEEHHHHHHHEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
ISFALKDEFKEFSEAYRIEQIIRKYSNFVDFPIFLGDNQINTISALWQRSKNEVSDEERN
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHH
EFYKFLSNDFNPPLDSLHLSVEGKVCFKALLFLPEEAPPELMYRQGDLESRGPQLYVKKV
HHHHHHHCCCCCCHHHEEEEECHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCHHHHHHHH
LIQQECRDLLPEYLRFVAGVVDTEDLPLNVSREVVQSSKVMANIRQILTGKILSWFESMA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TDQPEKFRKFYKAFGPFLKIGLNTDFTHRDRIIGLMRFESTKTAEGEYVTFKEYVERMEA
CCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHEEEEEECCCCCCCCCEEEHHHHHHHHHC
GQNEIYYHSGSNRIQLLAHPNLEYFQHKGIEVLLLSDPVDVFVIPSIHEYDKKPLKSIEK
CCCEEEEECCCCEEEEEECCCHHHHHCCCCEEEEEECCCCEEEECCHHHHCHHHHHHHHH
ADIDFTRTGDDKTEPPLPETLSQPLLGLFRQTIGDVIEDVVESHRLVSSPVTLVSGKDSL
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHH
DSSMEKMMKMMHAEMPAAKKILEVNTSHPIIKNLSGMIMANEHNPLIRTVIQQLYDGALL
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHCCCCEEEECCCCHHHHHHHHHHHCCCEE
HEGNLDATTGFLQRMNELIEAATMSR
ECCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA