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The map label for this gene is fabZ [H]

Identifier: 118578784

GI number: 118578784

Start: 343587

End: 344030

Strand: Direct

Name: fabZ [H]

Synonym: Ppro_0342

Alternate gene names: 118578784

Gene position: 343587-344030 (Clockwise)

Preceding gene: 118578783

Following gene: 118578785

Centisome position: 8.57

GC content: 56.98

Gene sequence:

>444_bases
ATGTATCTTGACGTTAATGAAATCATGAAGGTTTTACCGCATCGCCCCCCTTTCCTGATGGTTGACCGGATCATCGAGCT
GGAAGGCGGCGAGCGTTGCGTCGGCATCAAGAACACCACCATGGACGAGCACTTCTTCCAGGGACACTTTCCCGGCCATC
CGGTCATGCCCGGGGTTCTGATCGTGGAGGCCATGGCCCAGGTGGCCTGCCTGATGGCCTACAAGGCCGACGGCACTGAT
TATCACAACAAGGTCTGCTACTTCATGGCCATCGACAACGCCAAATTCAGGAAGCCGGTTTTCCCCGGCGACCAGTTGCG
CCTGGAAGTGACCACCCTGCAGCGTCGCCGCGGCGTGTGGGTGATCAGCGGCAAGACCTATGTCGAGGATACTCTGGTTT
GCGAGGCGGATTTCAAGGCAACGCTTGTGGATGCAAACCAATAA

Upstream 100 bases:

>100_bases
AGCTGCCAGGGAGAGGGGGTTTCTTTTGACTTTTTCATAAAGCGCTGATAGCATCGTTCGAATTTTCTGGTATACTCTTT
TTCCTGCGAGGAGGATGTAC

Downstream 100 bases:

>100_bases
TTTGAATACAGAGACGGAGGGAAACGGATGAACTTGGCAAAACAGGACGAATATCTGAATGAATGGCTGGACCACGAGGC
GTGCGCCGAAGAGATGCTTC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MYLDVNEIMKVLPHRPPFLMVDRIIELEGGERCVGIKNTTMDEHFFQGHFPGHPVMPGVLIVEAMAQVACLMAYKADGTD
YHNKVCYFMAIDNAKFRKPVFPGDQLRLEVTTLQRRRGVWVISGKTYVEDTLVCEADFKATLVDANQ

Sequences:

>Translated_147_residues
MYLDVNEIMKVLPHRPPFLMVDRIIELEGGERCVGIKNTTMDEHFFQGHFPGHPVMPGVLIVEAMAQVACLMAYKADGTD
YHNKVCYFMAIDNAKFRKPVFPGDQLRLEVTTLQRRRGVWVISGKTYVEDTLVCEADFKATLVDANQ
>Mature_147_residues
MYLDVNEIMKVLPHRPPFLMVDRIIELEGGERCVGIKNTTMDEHFFQGHFPGHPVMPGVLIVEAMAQVACLMAYKADGTD
YHNKVCYFMAIDNAKFRKPVFPGDQLRLEVTTLQRRRGVWVISGKTYVEDTLVCEADFKATLVDANQ

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=134, Percent_Identity=47.7611940298507, Blast_Score=140, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16722; Mature: 16722

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLDVNEIMKVLPHRPPFLMVDRIIELEGGERCVGIKNTTMDEHFFQGHFPGHPVMPGVL
CEECHHHHHHHCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCHHCCCCCCCCCCCCHHH
IVEAMAQVACLMAYKADGTDYHNKVCYFMAIDNAKFRKPVFPGDQLRLEVTTLQRRRGVW
HHHHHHHHHHHHEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEEHHHCCEE
VISGKTYVEDTLVCEADFKATLVDANQ
EECCCEEECEEEEEECCCEEEEEECCC
>Mature Secondary Structure
MYLDVNEIMKVLPHRPPFLMVDRIIELEGGERCVGIKNTTMDEHFFQGHFPGHPVMPGVL
CEECHHHHHHHCCCCCCEEEEEEEEEECCCCEEEECCCCCCCCHHCCCCCCCCCCCCHHH
IVEAMAQVACLMAYKADGTDYHNKVCYFMAIDNAKFRKPVFPGDQLRLEVTTLQRRRGVW
HHHHHHHHHHHHEECCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEEHHHCCEE
VISGKTYVEDTLVCEADFKATLVDANQ
EECCCEEECEEEEEECCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA