Click here to switch to the map view.

The map label for this gene is uvsE [H]

Identifier: 118578581

GI number: 118578581

Start: 146650

End: 147327

Strand: Direct

Name: uvsE [H]

Synonym: Ppro_0136

Alternate gene names: 118578581

Gene position: 146650-147327 (Clockwise)

Preceding gene: 118578557

Following gene: 118578583

Centisome position: 3.66

GC content: 54.87

Gene sequence:

>678_bases
GTGGGCTACGGACTTGCTGAACTCCCCGACGGGGATGCCCTCAGGCACCTGCTCGGCACAATCAGGGTCTTTGCCCGGCA
ACATGACCTCCGCCTCAGCTTTCATCCTGACCAGTTTGTCGTAGTGTCCTCGCCGCATCCTGCGGTAGTTGCCAGCTCAA
TCCGGGAACTGGAGTACCAGGCATACCTGGCTGAGGAAGTGGGGACTGATGTCATCAATATCCATGCCGGCGGGGTTTAT
GGTGACAAACAGACGACTCTCGTAAAATTCTATCAGGTTTTTAGCGATCTGCCGGAAACCATCAGAATTCGGTTGACGCT
GGAAAATGATGATCACAGCTACACTGTGCGCGATCTGTTGCCGGTATGCGCACGGCCTTCCATTCCGTTGGTGTATGATG
TTCACCACCATCGCTGTAATCCAGACGGCCTGTCAATCGAGGATGCGATGCAACTGGCAGCAGAAATCTGGCAGATGACC
GGTCGGGAGCAGTACTGCCATCTGTCATCACCCCGGGCTGGCTGGTTCGCACGAAATCCCAAGCCCCATACCGATTACAT
CGATCTTGCGGATCTGCCCAACTGCTGGCTGGGACGGACAATGACGGTGGATATCGAAGCCAAAGCCAAGGAACTGGCGG
TGGTTACGTTGATGACTGAATTGAAAGGTCTACGGTGA

Upstream 100 bases:

>100_bases
GGTGTCACGACATACTACCTCATTTTTTACACCCTCTATCAATGGCATGGAAACCGAGGCCGGTACGGGGGTATGAGCCC
TACCCGGCAAGTATCCTGAA

Downstream 100 bases:

>100_bases
AGGAGCAGAAATCTGGTTCCATCGCTGGAGGGTGTTTGTCATGGCCTGTGCCGAACTGTTTGGCTATAACAACGGCAATG
AATGGTTTATCGGGCACTAC

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MGYGLAELPDGDALRHLLGTIRVFARQHDLRLSFHPDQFVVVSSPHPAVVASSIRELEYQAYLAEEVGTDVINIHAGGVY
GDKQTTLVKFYQVFSDLPETIRIRLTLENDDHSYTVRDLLPVCARPSIPLVYDVHHHRCNPDGLSIEDAMQLAAEIWQMT
GREQYCHLSSPRAGWFARNPKPHTDYIDLADLPNCWLGRTMTVDIEAKAKELAVVTLMTELKGLR

Sequences:

>Translated_225_residues
MGYGLAELPDGDALRHLLGTIRVFARQHDLRLSFHPDQFVVVSSPHPAVVASSIRELEYQAYLAEEVGTDVINIHAGGVY
GDKQTTLVKFYQVFSDLPETIRIRLTLENDDHSYTVRDLLPVCARPSIPLVYDVHHHRCNPDGLSIEDAMQLAAEIWQMT
GREQYCHLSSPRAGWFARNPKPHTDYIDLADLPNCWLGRTMTVDIEAKAKELAVVTLMTELKGLR
>Mature_224_residues
GYGLAELPDGDALRHLLGTIRVFARQHDLRLSFHPDQFVVVSSPHPAVVASSIRELEYQAYLAEEVGTDVINIHAGGVYG
DKQTTLVKFYQVFSDLPETIRIRLTLENDDHSYTVRDLLPVCARPSIPLVYDVHHHRCNPDGLSIEDAMQLAAEIWQMTG
REQYCHLSSPRAGWFARNPKPHTDYIDLADLPNCWLGRTMTVDIEAKAKELAVVTLMTELKGLR

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 25375; Mature: 25244

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYGLAELPDGDALRHLLGTIRVFARQHDLRLSFHPDQFVVVSSPHPAVVASSIRELEYQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHH
AYLAEEVGTDVINIHAGGVYGDKQTTLVKFYQVFSDLPETIRIRLTLENDDHSYTVRDLL
HHHHHHHCCCEEEEEECCEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHH
PVCARPSIPLVYDVHHHRCNPDGLSIEDAMQLAAEIWQMTGREQYCHLSSPRAGWFARNP
HHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCC
KPHTDYIDLADLPNCWLGRTMTVDIEAKAKELAVVTLMTELKGLR
CCCCCEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GYGLAELPDGDALRHLLGTIRVFARQHDLRLSFHPDQFVVVSSPHPAVVASSIRELEYQ
CCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHH
AYLAEEVGTDVINIHAGGVYGDKQTTLVKFYQVFSDLPETIRIRLTLENDDHSYTVRDLL
HHHHHHHCCCEEEEEECCEECCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEHHHHH
PVCARPSIPLVYDVHHHRCNPDGLSIEDAMQLAAEIWQMTGREQYCHLSSPRAGWFARNP
HHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCC
KPHTDYIDLADLPNCWLGRTMTVDIEAKAKELAVVTLMTELKGLR
CCCCCEEECCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA