Click here to switch to the map view.

The map label for this gene is moaE [H]

Identifier: 118478810

GI number: 118478810

Start: 3394397

End: 3394870

Strand: Reverse

Name: moaE [H]

Synonym: BALH_3204

Alternate gene names: 118478810

Gene position: 3394870-3394397 (Counterclockwise)

Preceding gene: 118478811

Following gene: 118478809

Centisome position: 64.58

GC content: 39.03

Gene sequence:

>474_bases
GTGATTCTAATGGGGCAAGTGCTATTTGAAATTGTAGATATACCGATTGTAGTTGAAGAAGTAACGAATAAGGTTGCAAG
AAGAGACGCAGGTGCGATTACAACTTTTATTGGTACAGTGAGAGAATTAACAAAAGGAAAACGAACACTGCATTTAGAGT
ATGAAGCATATAAACCGATGGCAGTAAAACAACTTACGAGAATTGGGGAAGAAATAAATGAAAAGTGGCCAGACGCAAAA
GTAGCAATTACGCACCGAGTAGGACGGCTAGAAATAATGGATATTGCGGTAGTCATTGCAGTTTCATCACCGCATCGCAA
AGTAGCTTATGAAGCGAATGAATACGCAATTGAACGTATAAAGCGAATTGTCCCAATATGGAAAAAAGAATTTTGGGAAG
ATGGAACGATGTGGATTGGAGACCAGCTTGAAAATACACCTTATCCAGAAGGAAAACCGAAGAAGGAAGAATGA

Upstream 100 bases:

>100_bases
GGTGGTACGAGAGGTTATAAAAAAGGTATGTTCGTAGATGTGCTCTTGTTGGAAGATAACGAAGGTAGTGAATGGCCTTG
GACATTTTATAAAGTGAGAG

Downstream 100 bases:

>100_bases
GAAAATGATTACAATTTTACTGTTTGCAAATTTGCGTGAGGAAGTCGGATTAGATCGATTAGTAATTTCCGAAAAACAAG
AAATGACTGTGCAGCAATTA

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MILMGQVLFEIVDIPIVVEEVTNKVARRDAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAK
VAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPEGKPKKEE

Sequences:

>Translated_157_residues
MILMGQVLFEIVDIPIVVEEVTNKVARRDAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAK
VAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPEGKPKKEE
>Mature_157_residues
MILMGQVLFEIVDIPIVVEEVTNKVARRDAGAITTFIGTVRELTKGKRTLHLEYEAYKPMAVKQLTRIGEEINEKWPDAK
VAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERIKRIVPIWKKEFWEDGTMWIGDQLENTPYPEGKPKKEE

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=127, Percent_Identity=42.5196850393701, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI1787003, Length=126, Percent_Identity=35.7142857142857, Blast_Score=80, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17509279, Length=127, Percent_Identity=37.7952755905512, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356259, Length=125, Percent_Identity=40.8, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18073; Mature: 18073

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMGQVLFEIVDIPIVVEEVTNKVARRDAGAITTFIGTVRELTKGKRTLHLEYEAYKPM
CEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
AVKQLTRIGEEINEKWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERI
HHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHH
KRIVPIWKKEFWEDGTMWIGDQLENTPYPEGKPKKEE
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILMGQVLFEIVDIPIVVEEVTNKVARRDAGAITTFIGTVRELTKGKRTLHLEYEAYKPM
CEEHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCH
AVKQLTRIGEEINEKWPDAKVAITHRVGRLEIMDIAVVIAVSSPHRKVAYEANEYAIERI
HHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECHHHHHHHHH
KRIVPIWKKEFWEDGTMWIGDQLENTPYPEGKPKKEE
HHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]