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The map label for this gene is mrp [H]

Identifier: 118478809

GI number: 118478809

Start: 3393040

End: 3394098

Strand: Reverse

Name: mrp [H]

Synonym: BALH_3203

Alternate gene names: 118478809

Gene position: 3394098-3393040 (Counterclockwise)

Preceding gene: 118478810

Following gene: 118478808

Centisome position: 64.56

GC content: 36.92

Gene sequence:

>1059_bases
ATGAGTTCTATGCTTAATCAAGAACAAATAATGAACGCGTTAAAACATGTAGAGGATCCAGAGTTACACAAAAGTATTGT
AGAATTAAATATGGTTAGAAATATACAAATGAATGGAACAGAGGTTAAACTTGAAGTAGTGCTAACGATTCAAGGTTGTC
CGTTAAAAGCAAAAATTCAACAAGATATTGAAGAATCACTTCATGCAATTGGTGCCTCTAAAGTGGATTTAATATTTGGT
TCTATGACAAGTGAAGAACGTGCAGCTTTAACAGAGAAGTTAAAGAAAAATACTAGAACAGAAACTGGTATGCCGAACAT
GCTTCGCCCTGATTCAGGGGTACAATTTATTACTGTAACGAGCGGAAAAGGTGGAGTCGGAAAATCAACTGTGACAATTA
ATCTTGCAACGGCTTTAGCTCGTATGGGCAAAAAAGTGGGGATATTAGATGCAGATATATATGGTTTTAGCATTCCAGCT
ATGATGGAAACGAATCAAAAACCAACGATGATTGATCAAACGGCAATTCCAGTCGTTAGTCACGGTGTTAAAATTATGTC
TATGGGATTTTTTACAGAAGGAAATAATCCGGTTATGTGGCGCGGACCGATGTTAAATAAATGGATTCAAAATTTCCTTG
CGAATACGCACTGGGGAGAATTAGATTATTTACTTCTTGATTTACCACCTGGTACAGGAGATGTTGCCATTGATGTTGCA
GCAATGATTCCGCAAGCGAAAGAAATTATCGTTACAACTCCGCACAATGTAGCTTCATTCGTAGCATCTAGAGTAGGTGT
AATGGCAAAACATACGAAACATAAGATTTTAGGTATTGTGGAAAATATGGCGTATTTTGAAGAACAAGATGGATCGAAAA
ATTACCTCTTCGGAAAAGGTGGCGGCGAAATGCTTGCAGAACAATTGCAAACAGAAGTAATCGCACAAGTACCCTTTGCA
AAACGTGAAGAAAATAACGGTTCATCTGTATATGATGAAGATTCTCTTGTTGGAGAAGTGTTTACATCGTTAGCGGAAGA
TATTATTTATAAAGGATAG

Upstream 100 bases:

>100_bases
TGGAGATATCGTCGCATTCATCCCACCTGTTAGTGGGGGATAATAAGCGTTTCTTGAAACGATAAGAAGATGCTATATAT
AAATTCGAATACGAGAAGGG

Downstream 100 bases:

>100_bases
AGGAGGAATTTTATTATGGGGTGTAATATCGATCATTCTATTGAAGATGTAATGAGTAAGCTTGAAAGTCAAAAGAGTTT
TTTACCGGAAGTGATTTTTA

Product: ATP-binding mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSSMLNQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLHAIGASKVDLIFG
SMTSEERAALTEKLKKNTRTETGMPNMLRPDSGVQFITVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPA
MMETNQKPTMIDQTAIPVVSHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVA
AMIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHKILGIVENMAYFEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFA
KREENNGSSVYDEDSLVGEVFTSLAEDIIYKG

Sequences:

>Translated_352_residues
MSSMLNQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLHAIGASKVDLIFG
SMTSEERAALTEKLKKNTRTETGMPNMLRPDSGVQFITVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPA
MMETNQKPTMIDQTAIPVVSHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVA
AMIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHKILGIVENMAYFEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFA
KREENNGSSVYDEDSLVGEVFTSLAEDIIYKG
>Mature_351_residues
SSMLNQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQQDIEESLHAIGASKVDLIFGS
MTSEERAALTEKLKKNTRTETGMPNMLRPDSGVQFITVTSGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAM
METNQKPTMIDQTAIPVVSHGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVAA
MIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHKILGIVENMAYFEEQDGSKNYLFGKGGGEMLAEQLQTEVIAQVPFAK
REENNGSSVYDEDSLVGEVFTSLAEDIIYKG

Specific function: Negatively regulates the expression of hpr/scoC. The effect on hpr/scoC may be indirect [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family [H]

Homologues:

Organism=Homo sapiens, GI157384956, Length=234, Percent_Identity=40.1709401709402, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI6912540, Length=214, Percent_Identity=39.2523364485981, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI118572611, Length=215, Percent_Identity=35.3488372093023, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI87082045, Length=234, Percent_Identity=44.017094017094, Blast_Score=177, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI25143050, Length=251, Percent_Identity=37.0517928286853, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322188, Length=244, Percent_Identity=38.1147540983607, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321347, Length=284, Percent_Identity=32.0422535211268, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI221511043, Length=253, Percent_Identity=39.5256916996047, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24667611, Length=246, Percent_Identity=38.6178861788618, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI19921440, Length=222, Percent_Identity=32.8828828828829, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019591
- InterPro:   IPR000808 [H]

Pfam domain/function: PF10609 ParA [H]

EC number: NA

Molecular weight: Translated: 38528; Mature: 38397

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSMLNQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQ
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCHHHHH
QDIEESLHAIGASKVDLIFGSMTSEERAALTEKLKKNTRTETGMPNMLRPDSGVQFITVT
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
SGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQKPTMIDQTAIPVVS
CCCCCCCCEEEEEEHHHHHHHCCCCCCEEECCCCCEECCHHHCCCCCCCEECHHCCHHHH
HGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVA
CCEEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHH
AMIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHKILGIVENMAYFEEQDGSKNYLFGKG
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GGEMLAEQLQTEVIAQVPFAKREENNGSSVYDEDSLVGEVFTSLAEDIIYKG
CHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSMLNQEQIMNALKHVEDPELHKSIVELNMVRNIQMNGTEVKLEVVLTIQGCPLKAKIQ
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCEEEEEEEEEEECCCCHHHHH
QDIEESLHAIGASKVDLIFGSMTSEERAALTEKLKKNTRTETGMPNMLRPDSGVQFITVT
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEE
SGKGGVGKSTVTINLATALARMGKKVGILDADIYGFSIPAMMETNQKPTMIDQTAIPVVS
CCCCCCCCEEEEEEHHHHHHHCCCCCCEEECCCCCEECCHHHCCCCCCCEECHHCCHHHH
HGVKIMSMGFFTEGNNPVMWRGPMLNKWIQNFLANTHWGELDYLLLDLPPGTGDVAIDVA
CCEEEEEEEEEECCCCEEEEECHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEHH
AMIPQAKEIIVTTPHNVASFVASRVGVMAKHTKHKILGIVENMAYFEEQDGSKNYLFGKG
HHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
GGEMLAEQLQTEVIAQVPFAKREENNGSSVYDEDSLVGEVFTSLAEDIIYKG
CHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7559346; 8969501; 9384377; 2517635 [H]