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The map label for this gene is adp [C]

Identifier: 118478619

GI number: 118478619

Start: 3189492

End: 3191654

Strand: Reverse

Name: adp [C]

Synonym: BALH_2998

Alternate gene names: 118478619

Gene position: 3191654-3189492 (Counterclockwise)

Preceding gene: 118478626

Following gene: 118478618

Centisome position: 60.71

GC content: 38.47

Gene sequence:

>2163_bases
ATGAAGTCATTTATCTTAAAAAAAGGAACAGCCCTTACTTTAACAGGAGCAATATTGGTTGGAGCGTTAGCGATACCTTC
TTATGAAAACGCACATGCGGTAAACAAAAGGACATCAATTGAACAAGTTATTGATAAAGCTGCCGATGCAAAGAATATTC
CAGGAGTTATTGTTACTGTGAAAAATGGAGAGGCAAGTTGGGCATATGCTTCTGGTGAAGGTAATATTGAGAGAAATCAT
AAAGTAGATGCTGATTCTGCTTTTAGAATTGGGAGCACAACAAAGACCTTTGTAGCTACAGTAGTATTGCAGCTTGCGGG
TGAAAAGAAGTTAAGTCTTGATGATACGGTAGAGAAATGGTTGCCAGGACTTATTAAAGGGGAAGGCTATGATGGCAGCA
AAATTACGATTCGCCAACTATTAAATCATACAAGTGGAATTGCTGATTACTTGACTCCAGATCTTAAAGAGAAATTAATA
GAGAATCCAAGTGAGAATTATACAGCGGAACAATTAATTTCTCGTGCTTTACAATTGGAACCAGTAAAAGGATGGTCATA
CTCGAATACGAATATGGTTATTATTGGATTAATTATTCAGAAAGTAACAGGGGAATCATATGCTGAGCAGATACAAAAAC
GAATTATTAATCCTCTTAGTTTAAAAGAAACAGTTCTTCCTGGAAGCTCAATGGATATTCCGAAAAAAAATGCCCGTGGC
TATTTAAATACGGGAGATAAATTAGTAGATATTACATTGTTTAATCCATCGTTTGCTAATGCTAGTGGTGAAATGATTTC
GACAGGAGAAGATATGACAACGTTCTTCCGTGCCTTATTAGGTGGTAAATTACTTACACCGGAAATGCAGAAGGAGATGG
TGACTCACACAGTAGATACCCCATTAGGAAAGTATGGACTTGGTATTCACGCAACAAAATTACCAGATGGTACTGAAGTA
TGGGGACATGGTGGTGGTATCCCTGGTTTTACTAACTTTGCTGGTGGAACGAAAGATGGTCAGCATGTTATCTCGATAAA
TATTAATGTATTAGGCGCAGAGAAACAGATTAATAATATTTTAGCTTCAGAATTTGCGGAAAAATCAAAAAAGGAACCCA
CTAATAAGGAAAAGAAAAGCAAACATCGAGAAGAAGTACAAAATGTAATGGATCAAGTAGTAACGAATAAAAAAATTCCT
AGTGTTATAGCTGGCGGATTAAAGGATGGAAAGCGTTGGTCGTATGCTACCGGAACAGCTAGTTACGAGATGCCACGCCC
TGTAGAACCGAATTTTTCGTTCCGTATCGGAAGCATAACGAAGACATTCACTGCTTCTGTTGTACTGCAATTGGCTGAAG
AGAAACAATTAAACCTTGATGATACAGTTGAAAAATGGTTGCCGGGGGTTGTGCAGGGTAACGGATATGATGGGAGTAAA
ATTACAATTCGTCAGTTATTAAACCATACAAGTGGGATTGCAGCATATACTGATTTAGATATGCGAGATATTACATTGCC
TCAAAACCCATTTCGTTATTATAGTACCGATGAGCTCATAAGTTTAGCACTTGCAAAGCCTCCTGTATTTGCACCAGGGG
AGGGCTGGGACTATTCGAACACAAATACTGTTATAGCCGGGGAAATTATTCGGAAGGTAACAGGAGATACGTATGCGGAG
CAAATTAGAAAAAGATTTATTGAACCGCTCGGGTTAAAAGAAACATTCGTAATGGAAGCAAGTTCGCACATCCCGGGTAA
GCATGCTAATGGTTATAACATGGATAGATCAGGTCGTTTATATGATTTGACAGAAATTAATCAGTCATGGGCAAATGCAG
CTGGAGATATGGTTTCAACAGTGGAAGATTTGACTACATTCTTCAGTGCACTGTTAGGTGGGAAGCTCTTAAATCAAGAA
CTAATGAATCAGATGTTAACAACGGTAGATTCACCTATAGGTAAGGTTGGACTGGGAGTTTATGAAGAGAAAACACCAGA
CGGGCAATCGTATTGGGGACATGCTGGTGGGACTTTTGGATTTGAAACAAGGGTCGGTGGACCTATTGGAGGAGAACATA
TATTAGTAACTGCTATTAATGCAGTAGGTCCAGAAGTCATTACAGGCAGGGATAAAATATTTAATAAAGAATTTGGACGT
TAA

Upstream 100 bases:

>100_bases
ATAAATTAAAACGTTTTGTCACTATGTGATTTAACAATATTGAAGGTAAGGTGAGGGAGTGAGGCAACAGAAAAATTGAA
AATAATAGGAGCGATGCATA

Downstream 100 bases:

>100_bases
ATGTAAAATCGGCATTGGGCCTTCCGTTTTAAGGCTCAATGCCGATTTTCTTTATGTGATTTTGAATGTAATGGGAAATG
AAATCTTTGTATGATGATGC

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MKSFILKKGTALTLTGAILVGALAIPSYENAHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGEASWAYASGEGNIERNH
KVDADSAFRIGSTTKTFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGEGYDGSKITIRQLLNHTSGIADYLTPDLKEKLI
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAEKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHIPGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR

Sequences:

>Translated_720_residues
MKSFILKKGTALTLTGAILVGALAIPSYENAHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGEASWAYASGEGNIERNH
KVDADSAFRIGSTTKTFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGEGYDGSKITIRQLLNHTSGIADYLTPDLKEKLI
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAEKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHIPGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
>Mature_720_residues
MKSFILKKGTALTLTGAILVGALAIPSYENAHAVNKRTSIEQVIDKAADAKNIPGVIVTVKNGEASWAYASGEGNIERNH
KVDADSAFRIGSTTKTFVATVVLQLAGEKKLSLDDTVEKWLPGLIKGEGYDGSKITIRQLLNHTSGIADYLTPDLKEKLI
ENPSENYTAEQLISRALQLEPVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDTPLGKYGLGIHATKLPDGTEV
WGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNILASEFAEKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIP
SVIAGGLKDGKRWSYATGTASYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSNTNTVIAGEIIRKVTGDTYAE
QIRKRFIEPLGLKETFVMEASSHIPGKHANGYNMDRSGRLYDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQE
LMNQMLTTVDSPIGKVGLGVYEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=276, Percent_Identity=23.5507246376812, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=259, Percent_Identity=26.6409266409266, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565630, Length=291, Percent_Identity=25.7731958762887, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17550934, Length=211, Percent_Identity=27.4881516587678, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 78408; Mature: 78408

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFILKKGTALTLTGAILVGALAIPSYENAHAVNKRTSIEQVIDKAADAKNIPGVIVTV
CCCCEECCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
KNGEASWAYASGEGNIERNHKVDADSAFRIGSTTKTFVATVVLQLAGEKKLSLDDTVEKW
ECCCCCEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPGLIKGEGYDGSKITIRQLLNHTSGIADYLTPDLKEKLIENPSENYTAEQLISRALQLE
CCHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC
PVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
CCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDT
CCCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLGKYGLGIHATKLPDGTEVWGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNI
CCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHH
LASEFAEKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIPSVIAGGLKDGKRWSYATGTA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCC
SYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCH
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSN
HHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TNTVIAGEIIRKVTGDTYAEQIRKRFIEPLGLKETFVMEASSHIPGKHANGYNMDRSGRL
CCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCCCE
YDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQELMNQMLTTVDSPIGKVGLGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHCCCC
YEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MKSFILKKGTALTLTGAILVGALAIPSYENAHAVNKRTSIEQVIDKAADAKNIPGVIVTV
CCCCEECCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
KNGEASWAYASGEGNIERNHKVDADSAFRIGSTTKTFVATVVLQLAGEKKLSLDDTVEKW
ECCCCCEEEECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHH
LPGLIKGEGYDGSKITIRQLLNHTSGIADYLTPDLKEKLIENPSENYTAEQLISRALQLE
CCHHCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCC
PVKGWSYSNTNMVIIGLIIQKVTGESYAEQIQKRIINPLSLKETVLPGSSMDIPKKNARG
CCCCCCCCCCCEEEEEEHHHHHCCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCC
YLNTGDKLVDITLFNPSFANASGEMISTGEDMTTFFRALLGGKLLTPEMQKEMVTHTVDT
CCCCCCEEEEEEEECCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
PLGKYGLGIHATKLPDGTEVWGHGGGIPGFTNFAGGTKDGQHVISININVLGAEKQINNI
CCCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECHHHHHHH
LASEFAEKSKKEPTNKEKKSKHREEVQNVMDQVVTNKKIPSVIAGGLKDGKRWSYATGTA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCEEEECCCC
SYEMPRPVEPNFSFRIGSITKTFTASVVLQLAEEKQLNLDDTVEKWLPGVVQGNGYDGSK
CCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCCCCCH
ITIRQLLNHTSGIAAYTDLDMRDITLPQNPFRYYSTDELISLALAKPPVFAPGEGWDYSN
HHHHHHHCCCCCEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
TNTVIAGEIIRKVTGDTYAEQIRKRFIEPLGLKETFVMEASSHIPGKHANGYNMDRSGRL
CCEEEHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCCCCCCCCE
YDLTEINQSWANAAGDMVSTVEDLTTFFSALLGGKLLNQELMNQMLTTVDSPIGKVGLGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHCCCC
YEEKTPDGQSYWGHAGGTFGFETRVGGPIGGEHILVTAINAVGPEVITGRDKIFNKEFGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]