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The map label for this gene is hblA [H]

Identifier: 118478435

GI number: 118478435

Start: 2965152

End: 2966585

Strand: Reverse

Name: hblA [H]

Synonym: BALH_2803

Alternate gene names: 118478435

Gene position: 2966585-2965152 (Counterclockwise)

Preceding gene: 118478436

Following gene: 118478434

Centisome position: 56.43

GC content: 32.91

Gene sequence:

>1434_bases
TTGAAACCATACCCTATAGAGGAGGAATACGAAATGATGAAAAAAATCCCTAATAAACTATTCGCTGTATCAGCATTTTT
AACTATAACAACTACTTATGCAGTCATACCAATAGAAACTTTTGCAATTGAAATTGAACAAACGAACACTGAAGATATGT
CTCTTTCAGCAAATGAAGAACAGATGAAAAAAGCTTTGCAAGATGCTGGTTTATTTGCAAAAGCTATGAATGAATATTCT
TATTTGCTAATTCATAATCCAGATGTGAGTTTTGAAGGAATAACTATTAATGGAAATGCAGATTTACCTAGTCAAATTGT
ACAAGATCAAAAGAATGCAAGAGCACATGCTGTTACATGGAATACACACGTAAAAAAACAGCTTTTAGATACATTGACAG
GCATTATAGAATACGATACAAAATTTGAAAATCATTATGAAACATTAGTAGAGGCGATCAATACTGGAAATGGAGATACT
TTAAAAAAAGGGATTACAGATTTACAAGGAGGAATTCAACAAAATCAAAAGTCTGCAAAAGTATTAATAGAAGAATTAAT
TCAATTAAAAAATGCTATTGGAGAAGATGTTAGAACATTTGGAAGTCATAAAGAGACATTGCAATCGATTTTAAAAAACC
AAGGTGCTGATGTGGAGGCTGACCAAAAGCGTCTAGAGGACCTTTTAGGACAAGTAAAATATCAGAAAGACATAGAATCT
AAGGGATTAGACATGGTGAAAATTCCCTTTATTCCAACCTTGATTGCTGGTGGCATAATGATAGGTGATGCAAGAGGTAA
GTTAGGTTGGCTAGAACCTGAATTAGCAAAATTGCGTCAGACTGTAGATTATAAAATAACATTGAATCGTGTAGTTGGAG
TTGCATTTCATAATATTAGTGATATGCATAGTATGCTTGATAGTGCTATCACTGCTCTTACTTATATGTCTACGCAATGG
GAGGATTTAGATTCTCAATATTCGGGTGTACTGAGACATATTGATAAAGCTGATCAAAAAGCTGATCAAAATAAATATAA
ATTCTTAACCCCTAGCTTGAATGCAGCGAAAAACAGTTGGAAAACATTAAAAACAGATGTTGTCACTTTGCAAGAAGGGA
TAAAAATTGCAGAGAAAAAAGAACAGGATTTTTTGAATCAGTTTCGTCCAGCAAACGTTTTCTACTTTTATAAAAAAATT
CATAACGCATACACTTTTGAAATAAAGACGGGAACAAATGCACCAAATGCGTCTTATAAAGTTATGAATTTAACTAAAAA
CACTGTTCATAATATGTGGAGCGGAGGGGCTAATACTAACATGTGGGCTGATTGGCTTTCATTCAATCCAAATGATGAAT
TTGCGGTAGTAGCAGTAGTGGGTGGTAAAGAATATGTTGTGTATAAAGACAAAGTACAAAATATAATGAACTGA

Upstream 100 bases:

>100_bases
ATACTTAATGATTTGAAGACTGCTAAAGAAAGTTCAAACGATACTGATAAAAGATGTAGAACTTATTTTGAAAGACATCG
CTTTTTAATAAGATTAGAAC

Downstream 100 bases:

>100_bases
ATCTGAAAAGTAACGAAGTAATTGGAGCCGGACAATAAACTAGACACCAAGTTAATTGAAAAATTGCAATGGCATATATC
TCCTTATGTCCTAGAATACT

Product: hemolysin BL binding component (hemolytic enterotoxin HBL)

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKPYPIEEEYEMMKKIPNKLFAVSAFLTITTTYAVIPIETFAIEIEQTNTEDMSLSANEEQMKKALQDAGLFAKAMNEYS
YLLIHNPDVSFEGITINGNADLPSQIVQDQKNARAHAVTWNTHVKKQLLDTLTGIIEYDTKFENHYETLVEAINTGNGDT
LKKGITDLQGGIQQNQKSAKVLIEELIQLKNAIGEDVRTFGSHKETLQSILKNQGADVEADQKRLEDLLGQVKYQKDIES
KGLDMVKIPFIPTLIAGGIMIGDARGKLGWLEPELAKLRQTVDYKITLNRVVGVAFHNISDMHSMLDSAITALTYMSTQW
EDLDSQYSGVLRHIDKADQKADQNKYKFLTPSLNAAKNSWKTLKTDVVTLQEGIKIAEKKEQDFLNQFRPANVFYFYKKI
HNAYTFEIKTGTNAPNASYKVMNLTKNTVHNMWSGGANTNMWADWLSFNPNDEFAVVAVVGGKEYVVYKDKVQNIMN

Sequences:

>Translated_477_residues
MKPYPIEEEYEMMKKIPNKLFAVSAFLTITTTYAVIPIETFAIEIEQTNTEDMSLSANEEQMKKALQDAGLFAKAMNEYS
YLLIHNPDVSFEGITINGNADLPSQIVQDQKNARAHAVTWNTHVKKQLLDTLTGIIEYDTKFENHYETLVEAINTGNGDT
LKKGITDLQGGIQQNQKSAKVLIEELIQLKNAIGEDVRTFGSHKETLQSILKNQGADVEADQKRLEDLLGQVKYQKDIES
KGLDMVKIPFIPTLIAGGIMIGDARGKLGWLEPELAKLRQTVDYKITLNRVVGVAFHNISDMHSMLDSAITALTYMSTQW
EDLDSQYSGVLRHIDKADQKADQNKYKFLTPSLNAAKNSWKTLKTDVVTLQEGIKIAEKKEQDFLNQFRPANVFYFYKKI
HNAYTFEIKTGTNAPNASYKVMNLTKNTVHNMWSGGANTNMWADWLSFNPNDEFAVVAVVGGKEYVVYKDKVQNIMN
>Mature_477_residues
MKPYPIEEEYEMMKKIPNKLFAVSAFLTITTTYAVIPIETFAIEIEQTNTEDMSLSANEEQMKKALQDAGLFAKAMNEYS
YLLIHNPDVSFEGITINGNADLPSQIVQDQKNARAHAVTWNTHVKKQLLDTLTGIIEYDTKFENHYETLVEAINTGNGDT
LKKGITDLQGGIQQNQKSAKVLIEELIQLKNAIGEDVRTFGSHKETLQSILKNQGADVEADQKRLEDLLGQVKYQKDIES
KGLDMVKIPFIPTLIAGGIMIGDARGKLGWLEPELAKLRQTVDYKITLNRVVGVAFHNISDMHSMLDSAITALTYMSTQW
EDLDSQYSGVLRHIDKADQKADQNKYKFLTPSLNAAKNSWKTLKTDVVTLQEGIKIAEKKEQDFLNQFRPANVFYFYKKI
HNAYTFEIKTGTNAPNASYKVMNLTKNTVHNMWSGGANTNMWADWLSFNPNDEFAVVAVVGGKEYVVYKDKVQNIMN

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 53832; Mature: 53832

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPYPIEEEYEMMKKIPNKLFAVSAFLTITTTYAVIPIETFAIEIEQTNTEDMSLSANEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCCCCHH
QMKKALQDAGLFAKAMNEYSYLLIHNPDVSFEGITINGNADLPSQIVQDQKNARAHAVTW
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
NTHVKKQLLDTLTGIIEYDTKFENHYETLVEAINTGNGDTLKKGITDLQGGIQQNQKSAK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHH
VLIEELIQLKNAIGEDVRTFGSHKETLQSILKNQGADVEADQKRLEDLLGQVKYQKDIES
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KGLDMVKIPFIPTLIAGGIMIGDARGKLGWLEPELAKLRQTVDYKITLNRVVGVAFHNIS
CCCCEEECCCHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHH
DMHSMLDSAITALTYMSTQWEDLDSQYSGVLRHIDKADQKADQNKYKFLTPSLNAAKNSW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
KTLKTDVVTLQEGIKIAEKKEQDFLNQFRPANVFYFYKKIHNAYTFEIKTGTNAPNASYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCEE
VMNLTKNTVHNMWSGGANTNMWADWLSFNPNDEFAVVAVVGGKEYVVYKDKVQNIMN
EEECHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEEECCCEEEEEHHHHHHHCC
>Mature Secondary Structure
MKPYPIEEEYEMMKKIPNKLFAVSAFLTITTTYAVIPIETFAIEIEQTNTEDMSLSANEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEEECCCCCCCCCCCCHH
QMKKALQDAGLFAKAMNEYSYLLIHNPDVSFEGITINGNADLPSQIVQDQKNARAHAVTW
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEE
NTHVKKQLLDTLTGIIEYDTKFENHYETLVEAINTGNGDTLKKGITDLQGGIQQNQKSAK
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHH
VLIEELIQLKNAIGEDVRTFGSHKETLQSILKNQGADVEADQKRLEDLLGQVKYQKDIES
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KGLDMVKIPFIPTLIAGGIMIGDARGKLGWLEPELAKLRQTVDYKITLNRVVGVAFHNIS
CCCCEEECCCHHHHHHCCEEEECCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHH
DMHSMLDSAITALTYMSTQWEDLDSQYSGVLRHIDKADQKADQNKYKFLTPSLNAAKNSW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHH
KTLKTDVVTLQEGIKIAEKKEQDFLNQFRPANVFYFYKKIHNAYTFEIKTGTNAPNASYK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCCCCCEE
VMNLTKNTVHNMWSGGANTNMWADWLSFNPNDEFAVVAVVGGKEYVVYKDKVQNIMN
EEECHHHHHHHHHCCCCCCCCHHHHHCCCCCCCEEEEEEECCCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]