Click here to switch to the map view.

The map label for this gene is hblA [H]

Identifier: 118478436

GI number: 118478436

Start: 2966929

End: 2968071

Strand: Reverse

Name: hblA [H]

Synonym: BALH_2804

Alternate gene names: 118478436

Gene position: 2968071-2966929 (Counterclockwise)

Preceding gene: 118478437

Following gene: 118478435

Centisome position: 56.46

GC content: 33.95

Gene sequence:

>1143_bases
TTGGAGGAAAATGAAATGATAAAAAAAATCCCTTACAAATTACTCGCTGTATCGACGTTATTAACTATTACAACCGCTAA
TGTAGTTTCACCTGTAGCAACTTTTGCAAGTGAAATTGAACAAACGAACAATGGAGATACGGCTCTTTCTGCAAATGAAG
CGAAGATGAAAGAAACTTTGCAAAAGGCTGGATTATTTGCAAAATCTATGAATGCCTATTCTTATATGTTAATTAAAAAT
CCTGATGTGAATTTTGAGGGAATTACTATTAATGGATATGTAGATTTACCTGGTAGAATCGTACAAGATCAAAAGAATGC
AAGAGCACATGCTGTTACTTGGGATACGAAAGTGAAAAAACAGCTTTTAGATACATTGACTGGTATTGTTGAATATGATA
CGACGTTTGACAATTATTATGAAACAATGGTAGAGGCAATTAATACAGGGGATGGAGAAACTTTAAAAGAAGGGATTACA
GATTTGCGAGGTGAAATTCAACAAAATCAAAAGTATGCACAACAACTAATAGAAGAATTAACTAAATTAAGAGACTCTAT
TGGACACGATGTTAGAGCATTTGGAAGTAATAAAGAGCTCTTGCAGTCAATTTTAAAAAATCAAGGTGCAGATGTTGATG
CCGATCAAAAGCGTCTAGAAGAAGTATTAGGATCAGTAAACTATTATAAACAATTAGAATCTGATGGGTTTAATGTAATG
AAGGGTGCTATTTTGGGTCTACCAATAATTGGCGGTATCATAGTGGGAGTAGCAAGAGATAATTTAGGTAAGTTAGAGCC
TTTATTAGCAGAATTACGTCAGACCGTGGATTATAAAGTAACCTTAAATCGTGTAGTTGGAGTTGCTTACAGTAATATTA
ATGAAATGCACAAGGCGCTTGATGATGCTATTAACGCTCTTACTTATATGTCCACGCAGTGGCATGATTTAGATTCTCAA
TATTCGGGCGTTCTAGGGCATATTGAGAATGCAGCTCAAAAAGCCGATCAAAATAAATTTAAATTCTTAAAACCTAATTT
AAATGCAGCGAAAGACAGTTGGAAAACATTACGAACAGATGCTGTTACATTAAAAGAAGGAATAAAGGAGTTAAAAGTAG
AAACTGTTACTCCACAAAAATAG

Upstream 100 bases:

>100_bases
AGCCGCTAAAGAAAGTTGGAATGATATTCATAAAGATGCAGAATTCATTTCAAAAGATATTGCTTTTAAACAGGAGTAGA
ACTGAAATTTAAAACCTAAA

Downstream 100 bases:

>100_bases
GGAAATATTAATTCTGTTGTAAAGTGAACTAAAACATAGAAAGTCTATGATTATACTGTTAAACAGAAAAGTGATAATTA
ATAAATCCTTATATAACAGA

Product: hemolysin BL binding component B (hemolytic enterotoxin HBL)

Products: NA

Alternate protein names: Enterotoxin 40 kDa subunit [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MEENEMIKKIPYKLLAVSTLLTITTANVVSPVATFASEIEQTNNGDTALSANEAKMKETLQKAGLFAKSMNAYSYMLIKN
PDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLTGIVEYDTTFDNYYETMVEAINTGDGETLKEGIT
DLRGEIQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVM
KGAILGLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQ
YSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Sequences:

>Translated_380_residues
MEENEMIKKIPYKLLAVSTLLTITTANVVSPVATFASEIEQTNNGDTALSANEAKMKETLQKAGLFAKSMNAYSYMLIKN
PDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLTGIVEYDTTFDNYYETMVEAINTGDGETLKEGIT
DLRGEIQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVM
KGAILGLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQ
YSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK
>Mature_380_residues
MEENEMIKKIPYKLLAVSTLLTITTANVVSPVATFASEIEQTNNGDTALSANEAKMKETLQKAGLFAKSMNAYSYMLIKN
PDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKKQLLDTLTGIVEYDTTFDNYYETMVEAINTGDGETLKEGIT
DLRGEIQQNQKYAQQLIEELTKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVM
KGAILGLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKALDDAINALTYMSTQWHDLDSQ
YSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTDAVTLKEGIKELKVETVTPQK

Specific function: Cytotoxic protein, part of the enterotoxin complex. Responsible for binding to erythrocytes. This enterotoxin is thought to be the cause of the diarrheal form of gastroenteritis caused by food-borne strains of B.cereus [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Host cell membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008414
- InterPro:   IPR010356 [H]

Pfam domain/function: PF05791 Bacillus_HBL [H]

EC number: NA

Molecular weight: Translated: 42241; Mature: 42241

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEENEMIKKIPYKLLAVSTLLTITTANVVSPVATFASEIEQTNNGDTALSANEAKMKETL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHH
QKAGLFAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKK
HHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHH
QLLDTLTGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVM
HHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
KGAILGLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
DDAINALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTD
HHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHH
AVTLKEGIKELKVETVTPQK
HHHHHHHHHHHEECCCCCCC
>Mature Secondary Structure
MEENEMIKKIPYKLLAVSTLLTITTANVVSPVATFASEIEQTNNGDTALSANEAKMKETL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHH
QKAGLFAKSMNAYSYMLIKNPDVNFEGITINGYVDLPGRIVQDQKNARAHAVTWDTKVKK
HHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCHHHCCCCCCCEEEEECHHHHHH
QLLDTLTGIVEYDTTFDNYYETMVEAINTGDGETLKEGITDLRGEIQQNQKYAQQLIEEL
HHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKLRDSIGHDVRAFGSNKELLQSILKNQGADVDADQKRLEEVLGSVNYYKQLESDGFNVM
HHHHHHHCCHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHH
KGAILGLPIIGGIIVGVARDNLGKLEPLLAELRQTVDYKVTLNRVVGVAYSNINEMHKAL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHH
DDAINALTYMSTQWHDLDSQYSGVLGHIENAAQKADQNKFKFLKPNLNAAKDSWKTLRTD
HHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHH
AVTLKEGIKELKVETVTPQK
HHHHHHHHHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7693651; 8319899 [H]