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The map label for this gene is kynB

Identifier: 118478120

GI number: 118478120

Start: 2641073

End: 2641702

Strand: Reverse

Name: kynB

Synonym: BALH_2477

Alternate gene names: 118478120

Gene position: 2641702-2641073 (Counterclockwise)

Preceding gene: 118478121

Following gene: 118478119

Centisome position: 50.25

GC content: 37.3

Gene sequence:

>630_bases
ATGAAAACATCAGAGTGGATTGATATTTCACAACCGCTAAATAATGATATTGCTACTTGGCCAGGGGATACACCATTCTC
GTATGAAGTTTCATGGTCAAAAGAAGAGAGTGGTTCAGTAAATGTCGGAAAGTTAACGATGAGTATTCATACAGGCACTC
ATATTGATGCACCGTTTCATTTTGATAATGAAGGAAAGAAAGTAATAGACTTAGATGTTCAAGTTTATGTCGGACCAGCG
CGAATCATTGACGTTTCTAATCTTGAAAGCATTGGGAAAAAGGAATTAGAGAAATTTCATTTAGAAGGCGTAGAACGCTT
GTTGTTACGCACATCTTCACATGGTAAAGCGAATGAATTCCCAGATATAATCCCACATTTACGTGCGGATATAGCACCAT
TTCTTTCAGAAAAAGGTATACGTTTAATCGGAGTGGATGTACCATCAGTTGATCCATTAGATGATAAAGAATTAGCAGCG
CATCATCAATTGTTTAAACATGGTATACACATTTTAGAAAATGTCGTACTAGATCATGTAGCAGATGGCGATTACGAACT
AATCGCATTACCACTTGCCTTATCAGATGCAGATGGAAGTCCAGTTCGAGCAGTTATTAGACCAATATAA

Upstream 100 bases:

>100_bases
CATACGAAGAAGTGTGGCATTCTGTTCAAATATTAAAGAAAATCATGAAAGATGAAGAATATAAGCAGTTTGAAAATAAG
CGAGAGGTTGTGGCATAAGT

Downstream 100 bases:

>100_bases
GTAGAAATATATATAAAGGGGCGTTTTGCTAATATGAAAGAAAATGAAAAGGTAATTATGGAAAAAGGGATTCATACGGA
CTTTAAAGAGAATATGACGT

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNEGKKVIDLDVQVYVGPA
RIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEFPDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAA
HHQLFKHGIHILENVVLDHVADGDYELIALPLALSDADGSPVRAVIRPI

Sequences:

>Translated_209_residues
MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNEGKKVIDLDVQVYVGPA
RIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEFPDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAA
HHQLFKHGIHILENVVLDHVADGDYELIALPLALSDADGSPVRAVIRPI
>Mature_209_residues
MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNEGKKVIDLDVQVYVGPA
RIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEFPDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAA
HHQLFKHGIHILENVVLDHVADGDYELIALPLALSDADGSPVRAVIRPI

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KYNB_BACAH (A0REX1)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_895271.1
- ProteinModelPortal:   A0REX1
- SMR:   A0REX1
- STRING:   A0REX1
- EnsemblBacteria:   EBBACT00000070210
- GeneID:   4542618
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_2477
- NMPDR:   fig|412694.5.peg.2405
- eggNOG:   COG1878
- GeneTree:   EBGT00050000003083
- HOGENOM:   HBG686791
- OMA:   FHFDNDG
- ProtClustDB:   CLSK904617
- BioCyc:   BTHU412694:BALH_2477-MONOMER
- InterPro:   IPR017484
- InterPro:   IPR007325
- TIGRFAMs:   TIGR03035

Pfam domain/function: PF04199 Cyclase

EC number: =3.5.1.9

Molecular weight: Translated: 23103; Mature: 23103

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFH
CCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCEECCCEE
FDNEGKKVIDLDVQVYVGPARIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEF
ECCCCCEEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
ADGDYELIALPLALSDADGSPVRAVIRPI
CCCCEEEEEEEEEEECCCCCCHHHEECCC
>Mature Secondary Structure
MKTSEWIDISQPLNNDIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFH
CCCCCCEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEEEEECCCEECCCEE
FDNEGKKVIDLDVQVYVGPARIIDVSNLESIGKKELEKFHLEGVERLLLRTSSHGKANEF
ECCCCCEEEEEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PDIIPHLRADIAPFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
ADGDYELIALPLALSDADGSPVRAVIRPI
CCCCEEEEEEEEEEECCCCCCHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA