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The map label for this gene is ampC [C]

Identifier: 118478118

GI number: 118478118

Start: 2639169

End: 2640224

Strand: Reverse

Name: ampC [C]

Synonym: BALH_2475

Alternate gene names: 118478118

Gene position: 2640224-2639169 (Counterclockwise)

Preceding gene: 118478119

Following gene: 118478116

Centisome position: 50.22

GC content: 33.05

Gene sequence:

>1056_bases
TTGGAATGTTCGCACGAAATTATAAAAACAAACCTGTCAGTTCATTACTGGCAGGTTTGTTTTTTATTTGAACACAAGTA
TGTTTTAATTAAAGCTACAAGATATAATAAATTAGGTAATGATTTAATTGGAGGTAAAGTATTGGATTTCAAGCAGCTAG
AAAATAAATTTGAAAAGAAAAAAGTAAATACATTTCTTGTTTATCAAGAAGGGGAATTAACAACTGAGTATTATAAAACA
CCCGAATGTGCAAATAACTTATATAAAATAAATTCGATTACAAAAAGCATTGTATCTATATTAATAGGTATTGCAATCGA
TAAAGCATATATAAATGATATACATACACCGATTACAGAGTGGATTGAAAATGTATCTAATGAAAAGCGGGATCTGACTC
TTTATCATTTATTAACGATGACTACAGGTGAGGATTGGAAAGAGTTCGGAAATGGAGTAGTGTTCCCAAATGATTTTGTA
GAATCGGATAACTGGGTGCAGTACATATTAGAAAAACCAATGATTGAAGAACCGGCTACAAAAATGAATTATAACTCAGG
CTCTTCGCATTTACTTAGTTACATTATCCAAAAAGCTACTGGAATGTCGACAGAACAGTTTGCGAAAAAATATGTATTTG
ATCCATTAGAAATTACCGAATATGAGTGGCAGCAAGATCCGCAAGGAATACATGTCGGCGGCTTCGGAATGAAAATGAAG
TCTAAAGATTTATTAAAGCTCGGTATATTATGTTTGCAGAATGGATATTGGCAGGGGAATGAAATCATATCATCAAAATG
GTTAGAAGAATCAAGTACGGCTCTATTTGAAACGTATGAACATGTCGGGGCGTATGGATATCACTGGTGGGTATTGAATA
ACGAAAGATTTCACATACCGTACTGTATGTACTTTGCTATGGGATATGGCGGACAATATATCGTTATCATTCCGCAGTTA
GAGGTGGTTGCTGTAATAAGTAGTCATATGCCAAAACGTGGACTTGTACCATTAAAATTATTTATTGAGCATATACAAGA
GAATTGCAATTTTTAA

Upstream 100 bases:

>100_bases
AAACGGTAGAACGCATTATCGGACATAAAATGGGAACAGGCGGCTCTTCAGGTGTATCTTATTTAAAACGAGTACTTGAT
CAACGTTTCTTCCCAGAGCT

Downstream 100 bases:

>100_bases
TAAGGGTACAAGTAAATCTATTCAATCCATTTCAATTGTTTCATTTCTTCACAATTGAAAGTAATTTAGAAATGAAAACC
TCACTGTTTATAATGTGAAC

Product: 6-aminohexanoate-dimer hydrolase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: 6-Aminohexanoate-Dimer Hydrolase; Beta-Lactamase Family Protein; Beta-Lactamase Class C; Hydrolase Transmembrane Protein; Hydrolase; Secreted Beta-Lactamase Family Protein; Beta-Lactamase Class C Family Protein; Beta-Lactamase Class C Protein; Amide Hydrolase; Membrane Or Secreted Beta-Lactamase Family Protein; Exported 6-Aminohexanoate-Dimer Hydrolase Protein; Beta-Lactamase Class C-Like Protein; 6-Aminohexanoate-Dimer Hydrolase Protein; Beta-Lactamase-Like Hydrolase

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MECSHEIIKTNLSVHYWQVCFLFEHKYVLIKATRYNKLGNDLIGGKVLDFKQLENKFEKKKVNTFLVYQEGELTTEYYKT
PECANNLYKINSITKSIVSILIGIAIDKAYINDIHTPITEWIENVSNEKRDLTLYHLLTMTTGEDWKEFGNGVVFPNDFV
ESDNWVQYILEKPMIEEPATKMNYNSGSSHLLSYIIQKATGMSTEQFAKKYVFDPLEITEYEWQQDPQGIHVGGFGMKMK
SKDLLKLGILCLQNGYWQGNEIISSKWLEESSTALFETYEHVGAYGYHWWVLNNERFHIPYCMYFAMGYGGQYIVIIPQL
EVVAVISSHMPKRGLVPLKLFIEHIQENCNF

Sequences:

>Translated_351_residues
MECSHEIIKTNLSVHYWQVCFLFEHKYVLIKATRYNKLGNDLIGGKVLDFKQLENKFEKKKVNTFLVYQEGELTTEYYKT
PECANNLYKINSITKSIVSILIGIAIDKAYINDIHTPITEWIENVSNEKRDLTLYHLLTMTTGEDWKEFGNGVVFPNDFV
ESDNWVQYILEKPMIEEPATKMNYNSGSSHLLSYIIQKATGMSTEQFAKKYVFDPLEITEYEWQQDPQGIHVGGFGMKMK
SKDLLKLGILCLQNGYWQGNEIISSKWLEESSTALFETYEHVGAYGYHWWVLNNERFHIPYCMYFAMGYGGQYIVIIPQL
EVVAVISSHMPKRGLVPLKLFIEHIQENCNF
>Mature_351_residues
MECSHEIIKTNLSVHYWQVCFLFEHKYVLIKATRYNKLGNDLIGGKVLDFKQLENKFEKKKVNTFLVYQEGELTTEYYKT
PECANNLYKINSITKSIVSILIGIAIDKAYINDIHTPITEWIENVSNEKRDLTLYHLLTMTTGEDWKEFGNGVVFPNDFV
ESDNWVQYILEKPMIEEPATKMNYNSGSSHLLSYIIQKATGMSTEQFAKKYVFDPLEITEYEWQQDPQGIHVGGFGMKMK
SKDLLKLGILCLQNGYWQGNEIISSKWLEESSTALFETYEHVGAYGYHWWVLNNERFHIPYCMYFAMGYGGQYIVIIPQL
EVVAVISSHMPKRGLVPLKLFIEHIQENCNF

Specific function: This Protein Is A Serine Beta-Lactamase With A Substrate Specificity For Cephalosporins. [C]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 40837; Mature: 40837

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECSHEIIKTNLSVHYWQVCFLFEHKYVLIKATRYNKLGNDLIGGKVLDFKQLENKFEKK
CCCCHHHHHHCCCCHHEEEEEEEECCEEEEEEECCCCCCCCCCCCCEECHHHHHHHHHHH
KVNTFLVYQEGELTTEYYKTPECANNLYKINSITKSIVSILIGIAIDKAYINDIHTPITE
CCCEEEEEECCCCCHHHHCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIENVSNEKRDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESDNWVQYILEKPMIEEPAT
HHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCH
KMNYNSGSSHLLSYIIQKATGMSTEQFAKKYVFDPLEITEYEWQQDPQGIHVGGFGMKMK
HCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEEECCCCCCCC
SKDLLKLGILCLQNGYWQGNEIISSKWLEESSTALFETYEHVGAYGYHWWVLNNERFHIP
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECH
YCMYFAMGYGGQYIVIIPQLEVVAVISSHMPKRGLVPLKLFIEHIQENCNF
HHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MECSHEIIKTNLSVHYWQVCFLFEHKYVLIKATRYNKLGNDLIGGKVLDFKQLENKFEKK
CCCCHHHHHHCCCCHHEEEEEEEECCEEEEEEECCCCCCCCCCCCCEECHHHHHHHHHHH
KVNTFLVYQEGELTTEYYKTPECANNLYKINSITKSIVSILIGIAIDKAYINDIHTPITE
CCCEEEEEECCCCCHHHHCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIENVSNEKRDLTLYHLLTMTTGEDWKEFGNGVVFPNDFVESDNWVQYILEKPMIEEPAT
HHHHHCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCCHHCCCCHHHHHHHCCCCCCCCCH
KMNYNSGSSHLLSYIIQKATGMSTEQFAKKYVFDPLEITEYEWQQDPQGIHVGGFGMKMK
HCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCCCCCCCCCCCEEECCCCCCCC
SKDLLKLGILCLQNGYWQGNEIISSKWLEESSTALFETYEHVGAYGYHWWVLNNERFHIP
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECH
YCMYFAMGYGGQYIVIIPQLEVVAVISSHMPKRGLVPLKLFIEHIQENCNF
HHHHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA