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The map label for this gene is llrF [H]

Identifier: 118476259

GI number: 118476259

Start: 590330

End: 591028

Strand: Direct

Name: llrF [H]

Synonym: BALH_0511

Alternate gene names: 118476259

Gene position: 590330-591028 (Clockwise)

Preceding gene: 118476258

Following gene: 118476260

Centisome position: 11.23

GC content: 34.62

Gene sequence:

>699_bases
TTGAACAATATGGTGGAAGGTGAGAATATGCGCTTACTCGTAGTAGAAGATAATGCTTCTTTATTAGAATCTATTGTCCA
AATATTACACGACGAATTTGAAGTAGATACAGCATTGAATGGAGAAGAGGGATTATTTCTAGCATTACAAAATATATATG
ACGTAATTTTGCTTGATGTGATGATGCCAGAAATGGACGGTTTTGAAGTGATTCAAAAAATACGTGATGAAAAGATTGAA
ACACCAGTCCTATTTTTAACAGCGAGAGATTCTTTAGAAGATCGGGTGAAGGGATTGGATTTTGGTGGAGATGACTATAT
TGTTAAGCCATTTCAGGCTCCTGAATTAAAAGCGAGAATTCGTGCTTTACTACGCAGAAGTGGTAGTTTAACAACAAAGC
AAACCATTCGCTATAAAGGGATTGAACTGTTCGGAAAAGATAAAGATGTTCAAGTAAATGGACAAAGTATGAAGTTAACA
TTAAAACAATATGAGCTTCTAGAGTACCTTGTTCAAAATAGCGGAAAGATTTTAATGAGGGAACAAATTTTTGATCGTGT
CTGGGGATTCGATTCAGATACGACAGTAGCGATTGTAGAAGTGTATGTACATCATTTACGTAAAAAATTAGAGCCATTCG
GTTATCAGAAAGATATTCAAACCGTTCGTGGTATTGGATATATATTAAAAGAACAATGA

Upstream 100 bases:

>100_bases
TCTTTCAACTTTTTATTAAGCAAAATTTAAGGAAGAGTTTTTATAATAAGTCTTTCAAATTTTATATCAAAAAAACGTTA
AAATGTAATTATAAATAGAA

Downstream 100 bases:

>100_bases
AAAAGGGAAGCATGTTTCAGAAGACGCGTATTCGATTGACTATATTGAATTCATTAGTATTTATCATTTTGATAGGCGTA
TTAGGTAGTATCATTTATTC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNNMVEGENMRLLVVEDNASLLESIVQILHDEFEVDTALNGEEGLFLALQNIYDVILLDVMMPEMDGFEVIQKIRDEKIE
TPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGSLTTKQTIRYKGIELFGKDKDVQVNGQSMKLT
LKQYELLEYLVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ

Sequences:

>Translated_232_residues
MNNMVEGENMRLLVVEDNASLLESIVQILHDEFEVDTALNGEEGLFLALQNIYDVILLDVMMPEMDGFEVIQKIRDEKIE
TPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGSLTTKQTIRYKGIELFGKDKDVQVNGQSMKLT
LKQYELLEYLVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
>Mature_232_residues
MNNMVEGENMRLLVVEDNASLLESIVQILHDEFEVDTALNGEEGLFLALQNIYDVILLDVMMPEMDGFEVIQKIRDEKIE
TPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARIRALLRRSGSLTTKQTIRYKGIELFGKDKDVQVNGQSMKLT
LKQYELLEYLVQNSGKILMREQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ

Specific function: Member of the two-component regulatory system CiaH/CiaR. Involved in early steps of competence regulation and in penicillin susceptibility [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=41.8918918918919, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=39.2857142857143, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=37.0535714285714, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=37.0535714285714, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=35, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=33.7837837837838, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=36.036036036036, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.2727272727273, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.1991341991342, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=29.8701298701299, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=27.4336283185841, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1787229, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=38.8888888888889, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693140, Length=240, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=32.8, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788713, Length=91, Percent_Identity=35.1648351648352, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26748; Mature: 26748

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMVEGENMRLLVVEDNASLLESIVQILHDEFEVDTALNGEEGLFLALQNIYDVILLDV
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
MMPEMDGFEVIQKIRDEKIETPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARI
HCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCCCHHHHHH
RALLRRSGSLTTKQTIRYKGIELFGKDKDVQVNGQSMKLTLKQYELLEYLVQNSGKILMR
HHHHHHCCCCCHHHHHHCCCEEEECCCCCEEECCCEEEEHHHHHHHHHHHHHCCCCEEHH
EQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNMVEGENMRLLVVEDNASLLESIVQILHDEFEVDTALNGEEGLFLALQNIYDVILLDV
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
MMPEMDGFEVIQKIRDEKIETPVLFLTARDSLEDRVKGLDFGGDDYIVKPFQAPELKARI
HCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCEECCCCCCHHHHHH
RALLRRSGSLTTKQTIRYKGIELFGKDKDVQVNGQSMKLTLKQYELLEYLVQNSGKILMR
HHHHHHCCCCCHHHHHHCCCEEEECCCCCEEECCCEEEEHHHHHHHHHHHHHCCCCEEHH
EQIFDRVWGFDSDTTVAIVEVYVHHLRKKLEPFGYQKDIQTVRGIGYILKEQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]