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The map label for this gene is argE [H]

Identifier: 118476183

GI number: 118476183

Start: 491115

End: 492437

Strand: Direct

Name: argE [H]

Synonym: BALH_0431

Alternate gene names: 118476183

Gene position: 491115-492437 (Clockwise)

Preceding gene: 118476182

Following gene: 118476186

Centisome position: 9.34

GC content: 39.15

Gene sequence:

>1323_bases
GTGAAAATAAAGCTGGAAACATACTACGTATGCAAAGGGGAATTAGCGATGAATCCAGAAGTTTCACAGTTATTAGAACA
GATTGAACTACGAAAAGATGAGTTACTAGAGCTTACAAAAACTTTAATTCGTTTTGAAACACCAGCACCGCCGGCGAGAA
ATACAAATGAGGCACAACAATTTGTTGCAGATTTTCTAAGAAAAAGAAATTTTAGTGTTGATAAATGGGATGTATATCCG
AATGATCCGAACGTTGTTGGGGTCAAAAAAGGGATAGAAAGTGAAACACATAAAAGTCTTATTATTAATGGACATATGGA
TGTAGCTGAAGTGTCAGCAGATGAGGCGTGGGAAAAAAATCCGTTTGAGCCATTTATAAAAGATGGTTGGTTAGTTGGAC
GTGGTGCAGCTGATATGAAAGGGGGACTAGCTGGAGCGCTATTTGCTATTCAGCTTTTAGAAGAAGCTGGCATTGAATTA
CCTGGAGATTTAATCTTTCAATCCGTAATTGGAGAAGAAGTTGGAGAGGCAGGTACACTTCAATGCTGTAGGCGAGGTTA
TGATGCTGATTTTGCAGTCGTAGTGGATACGAGTGATTTACATATGCAAGGACAGGGCGGCGTAATTACTGGGTGGATTA
CTGTGAAAAGCCCCCAAACGTTTCATGATGCAACGCGCAGACAAATGATCCATGCTGGAGGACGTTTATTCGGAGCGAGC
GCGATTGAAAAAATGATGAAAATTGTGCAAAGCTTACAAGAATTAGAGCGTCACTGGGCAGTCATGAAAACATATGAAGG
TTATCCGTCTGGAACAACAACAATTAATCCAGCTGTTATAGAAGGTGGACGGCATGCAGCGTTTATTGCGGATGAGTGCC
GTTTGTGGATAACAGTGCACTTTTATCCGAATGAAACACATGAACAAATAATAAAAGAAATTGAAGAGTATATCGGGAAA
GTAGCAGCTGCTGACCCATGGTTAAGTGAAAATCCACCACAATTTAAGTGGGGTGGAGAATCAATGATTGTGGATCGTGG
CGAAATTTTCCCTTCTTTAGAAATAGATAGTGAACATGCAGCTGTAAAAACGCTTAGCTCAGTACACGAATCAGTTCTTT
CTAAACATGCAATTTTAGATATGTCTGCAACGGTAACGGATGGTGGTTGGTTTAGTGAATTTCATATTCCGGCTGTTATT
TACGGACCAGGTACATTAGAAGAAGCTCATTCAATAAATGAGAAAGTTGAAGTAGAACAGTTAATTGAATTTACAAAAGT
AATAACAGCATTTATATATGAATGGTGTCATACGAAAAAATAG

Upstream 100 bases:

>100_bases
ATAAAGTAGAACATATTGAAAAGACAGATACAACAGAAGTAGAAAATTTATAATACTGAGTAATTTAGAGACTGTAAAAT
TGTAAACAGTCTCTTTTTTT

Downstream 100 bases:

>100_bases
ATTAGTATGTTGAAATCGTACAGGTATGTATACTTGTACGATTTTTTAGTGAACTATTTCAGAGTTGAATAGAAACAACT
GAAATAGTTCTTTATTTTTC

Product: acetylornithine deacetylase

Products: acetate; L-ornithine

Alternate protein names: Amidohydrolase; Formylaminopyrimidine deformylase [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKIKLETYYVCKGELAMNPEVSQLLEQIELRKDELLELTKTLIRFETPAPPARNTNEAQQFVADFLRKRNFSVDKWDVYP
NDPNVVGVKKGIESETHKSLIINGHMDVAEVSADEAWEKNPFEPFIKDGWLVGRGAADMKGGLAGALFAIQLLEEAGIEL
PGDLIFQSVIGEEVGEAGTLQCCRRGYDADFAVVVDTSDLHMQGQGGVITGWITVKSPQTFHDATRRQMIHAGGRLFGAS
AIEKMMKIVQSLQELERHWAVMKTYEGYPSGTTTINPAVIEGGRHAAFIADECRLWITVHFYPNETHEQIIKEIEEYIGK
VAAADPWLSENPPQFKWGGESMIVDRGEIFPSLEIDSEHAAVKTLSSVHESVLSKHAILDMSATVTDGGWFSEFHIPAVI
YGPGTLEEAHSINEKVEVEQLIEFTKVITAFIYEWCHTKK

Sequences:

>Translated_440_residues
MKIKLETYYVCKGELAMNPEVSQLLEQIELRKDELLELTKTLIRFETPAPPARNTNEAQQFVADFLRKRNFSVDKWDVYP
NDPNVVGVKKGIESETHKSLIINGHMDVAEVSADEAWEKNPFEPFIKDGWLVGRGAADMKGGLAGALFAIQLLEEAGIEL
PGDLIFQSVIGEEVGEAGTLQCCRRGYDADFAVVVDTSDLHMQGQGGVITGWITVKSPQTFHDATRRQMIHAGGRLFGAS
AIEKMMKIVQSLQELERHWAVMKTYEGYPSGTTTINPAVIEGGRHAAFIADECRLWITVHFYPNETHEQIIKEIEEYIGK
VAAADPWLSENPPQFKWGGESMIVDRGEIFPSLEIDSEHAAVKTLSSVHESVLSKHAILDMSATVTDGGWFSEFHIPAVI
YGPGTLEEAHSINEKVEVEQLIEFTKVITAFIYEWCHTKK
>Mature_440_residues
MKIKLETYYVCKGELAMNPEVSQLLEQIELRKDELLELTKTLIRFETPAPPARNTNEAQQFVADFLRKRNFSVDKWDVYP
NDPNVVGVKKGIESETHKSLIINGHMDVAEVSADEAWEKNPFEPFIKDGWLVGRGAADMKGGLAGALFAIQLLEEAGIEL
PGDLIFQSVIGEEVGEAGTLQCCRRGYDADFAVVVDTSDLHMQGQGGVITGWITVKSPQTFHDATRRQMIHAGGRLFGAS
AIEKMMKIVQSLQELERHWAVMKTYEGYPSGTTTINPAVIEGGRHAAFIADECRLWITVHFYPNETHEQIIKEIEEYIGK
VAAADPWLSENPPQFKWGGESMIVDRGEIFPSLEIDSEHAAVKTLSSVHESVLSKHAILDMSATVTDGGWFSEFHIPAVI
YGPGTLEEAHSINEKVEVEQLIEFTKVITAFIYEWCHTKK

Specific function: Catalyzed the deformylation of formylaminopyrimidine to give aminopyrimidine [H]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

Organism=Escherichia coli, GI1789236, Length=347, Percent_Identity=25.3602305475504, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=21.957671957672, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI193211059, Length=172, Percent_Identity=27.3255813953488, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010182
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: 3.5.1.16

Molecular weight: Translated: 49147; Mature: 49147

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKLETYYVCKGELAMNPEVSQLLEQIELRKDELLELTKTLIRFETPAPPARNTNEAQQ
CEEEEEEEEEEECCEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FVADFLRKRNFSVDKWDVYPNDPNVVGVKKGIESETHKSLIINGHMDVAEVSADEAWEKN
HHHHHHHHCCCCCCEEECCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHCCCHHCCCCC
PFEPFIKDGWLVGRGAADMKGGLAGALFAIQLLEEAGIELPGDLIFQSVIGEEVGEAGTL
CCCCHHHCCEEEECCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
QCCRRGYDADFAVVVDTSDLHMQGQGGVITGWITVKSPQTFHDATRRQMIHAGGRLFGAS
HHHHCCCCCCEEEEEECCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEECHH
AIEKMMKIVQSLQELERHWAVMKTYEGYPSGTTTINPAVIEGGRHAAFIADECRLWITVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCEEEEEECCCEEEEEEE
FYPNETHEQIIKEIEEYIGKVAAADPWLSENPPQFKWGGESMIVDRGEIFPSLEIDSEHA
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEEEECCCCCCCEEECCHHH
AVKTLSSVHESVLSKHAILDMSATVTDGGWFSEFHIPAVIYGPGTLEEAHSINEKVEVEQ
HHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEEEECCCCHHHHHHCHHHHHHHH
LIEFTKVITAFIYEWCHTKK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIKLETYYVCKGELAMNPEVSQLLEQIELRKDELLELTKTLIRFETPAPPARNTNEAQQ
CEEEEEEEEEEECCEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
FVADFLRKRNFSVDKWDVYPNDPNVVGVKKGIESETHKSLIINGHMDVAEVSADEAWEKN
HHHHHHHHCCCCCCEEECCCCCCCEEEECCCCCCCCCCEEEEECCCCHHHCCCHHCCCCC
PFEPFIKDGWLVGRGAADMKGGLAGALFAIQLLEEAGIELPGDLIFQSVIGEEVGEAGTL
CCCCHHHCCEEEECCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
QCCRRGYDADFAVVVDTSDLHMQGQGGVITGWITVKSPQTFHDATRRQMIHAGGRLFGAS
HHHHCCCCCCEEEEEECCCEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCEECHH
AIEKMMKIVQSLQELERHWAVMKTYEGYPSGTTTINPAVIEGGRHAAFIADECRLWITVH
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEECCCCEEEEEECCCEEEEEEE
FYPNETHEQIIKEIEEYIGKVAAADPWLSENPPQFKWGGESMIVDRGEIFPSLEIDSEHA
ECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEEEECCCCCCCEEECCHHH
AVKTLSSVHESVLSKHAILDMSATVTDGGWFSEFHIPAVIYGPGTLEEAHSINEKVEVEQ
HHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEEEECCCCHHHHHHCHHHHHHHH
LIEFTKVITAFIYEWCHTKK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N2-acetyl-L-ornithine; H2O

Specific reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]