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The map label for this gene is rocE [H]

Identifier: 118476182

GI number: 118476182

Start: 489589

End: 491067

Strand: Direct

Name: rocE [H]

Synonym: BALH_0430

Alternate gene names: 118476182

Gene position: 489589-491067 (Clockwise)

Preceding gene: 118476181

Following gene: 118476183

Centisome position: 9.31

GC content: 37.05

Gene sequence:

>1479_bases
ATGATTTTAAAAACGCTTACATTAAATGGGTTTCCAAAGGGAAAAGGGGGGGATTATATGATGGATCAAAATAAAGGATT
AAAACGGGAATTGAAAAGCAAGCACATATTTATGATTGCACTTGGAGGAGTTATTGGTACCGGTCTTTTTTTAGGATCTG
GGTATACAATTCATGAAGCTGGGCCTGGAGGAGCGATTGTAGCGTATCTTGTCGGAGGATTTGTTATGTATTTAACGATG
CTCTGTCTTGGAGAGTTAGCTGTTGCAATGCCTGACGCAGGATCTTATCAAACGTATGCTACGAAGCATATTTCCCCTGC
AGCGGGTTATGTAGTCGGATGGATGTCGTGGTTAAACTGGTCGGCTACAATAGGTATTGAACTAATTGCAGTTAGTATTT
TAATGAAACGATGGTTTCCTGATGTACCGTCTTGGATTTGGTGCGTAGTGTTTGCGGTACTACTTTTTGCTATTAACGCG
TTATCTTCAAGAAGTTTTGCAGAAGTTGAATTTTGGTTTGCAAGTATTAAAGTCATTACAATCATTGCATTTATTATTTT
GGGCGGGGCAGCAATGTTTGGTTTTCTAGATATGAAAGGAAATGAACCAGCACCAATGTTTTCTAGCTTTATTGATTATG
GTGGGTTGTTTCCAAATGGATTATCCGCTATTTTAATTACGATGATTGCAGTTAATTTTTCCTTCCAAGGAACGGAACTA
GTCGGTATTGCAGCAGGTGAGAGTGAAAATCCAGAGAAAACGATCCCGAAGGCAATTAATAATACAGTTTGGCGTATACT
CGTGTTCTTTGTATTATCTATTTTCATTCTTGCAGGATTATTCCCTTGGCAACAGGCGGGAGTAATAGAAAGTCCATTCG
TAGTTGTATTTGATAAAATTGGTATTCCTTATGCAGCCGATATTATCAATTTCGTTATTATTACAGCGGTTCTATCCGTT
GCGAATTCAGGATTATATGCAACTTCTCGTATGCTATGGTCTATGTCTAATCAAGGAATGATTAGTCCGATTTTTGGTAA
GTTATCTAAAAATGGTGTTCCTATTTATGCATTGATTGTAAGTACAATTGTAGGTTGCCTTTCATTACTATCAGGTATTT
ATGCGGAAGATACAGTTTATTTATGGCTACTTTCTATTGCCGGGTTCGGAGCGATATTAGTTTGGGCATCTATTGCTCTA
TCTAACTTATTAGCTAGAAGGTCATATATAAAGCAGGGCGGAGATGTGAAAGACTTGAAATTTAAAACACCACTGTATCC
ATTCGTACCGCTGCTTGCATTAGTATTAAATGTAACAGTAATTGTTGGTATGGCCTTTATTCCAGAACAAAGAATGGCGT
TATATTGTGGAATTCCATTTATGATTGTTTGCTTACTGTTTTACCGTGCGACAAGAAATAAGGCACATAAAGTAGAACAT
ATTGAAAAGACAGATACAACAGAAGTAGAAAATTTATAA

Upstream 100 bases:

>100_bases
AAAGTTATTAATAACAGTGAGGGATGATCTTTTAATAACAGGTAGTGATTAATATAAGTGCTATGTATTTTGCTCTTTTT
AATAATTATTTTTATTATGA

Downstream 100 bases:

>100_bases
TACTGAGTAATTTAGAGACTGTAAAATTGTAAACAGTCTCTTTTTTTGTGAAAATAAAGCTGGAAACATACTACGTATGC
AAAGGGGAATTAGCGATGAA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MILKTLTLNGFPKGKGGDYMMDQNKGLKRELKSKHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTM
LCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINA
LSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMKGNEPAPMFSSFIDYGGLFPNGLSAILITMIAVNFSFQGTEL
VGIAAGESENPEKTIPKAINNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSV
ANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIAL
SNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEH
IEKTDTTEVENL

Sequences:

>Translated_492_residues
MILKTLTLNGFPKGKGGDYMMDQNKGLKRELKSKHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTM
LCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINA
LSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMKGNEPAPMFSSFIDYGGLFPNGLSAILITMIAVNFSFQGTEL
VGIAAGESENPEKTIPKAINNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSV
ANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIAL
SNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEH
IEKTDTTEVENL
>Mature_492_residues
MILKTLTLNGFPKGKGGDYMMDQNKGLKRELKSKHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTM
LCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINA
LSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMKGNEPAPMFSSFIDYGGLFPNGLSAILITMIAVNFSFQGTEL
VGIAAGESENPEKTIPKAINNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSV
ANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIAL
SNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEH
IEKTDTTEVENL

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=51.5086206896552, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1788480, Length=476, Percent_Identity=40.9663865546218, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=466, Percent_Identity=38.6266094420601, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI48994972, Length=471, Percent_Identity=36.0934182590234, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1786789, Length=457, Percent_Identity=36.3238512035011, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=36.784140969163, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=36.304347826087, Blast_Score=275, Evalue=5e-75,
Organism=Escherichia coli, GI87081915, Length=426, Percent_Identity=37.0892018779343, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1790653, Length=446, Percent_Identity=35.6502242152466, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI87081869, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082250, Length=447, Percent_Identity=23.9373601789709, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI2367353, Length=350, Percent_Identity=26, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=224, Percent_Identity=27.6785714285714, Blast_Score=68, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=438, Percent_Identity=21.2328767123288, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17533459, Length=448, Percent_Identity=24.1071428571429, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=375, Percent_Identity=22.6666666666667, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324061, Length=497, Percent_Identity=31.58953722334, Blast_Score=246, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6320772, Length=440, Percent_Identity=34.3181818181818, Blast_Score=244, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=33.8271604938272, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6324059, Length=429, Percent_Identity=34.032634032634, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6320717, Length=437, Percent_Identity=30.4347826086957, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6319824, Length=416, Percent_Identity=30.7692307692308, Blast_Score=219, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=409, Percent_Identity=32.7628361858191, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324990, Length=505, Percent_Identity=29.7029702970297, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6319543, Length=428, Percent_Identity=29.4392523364486, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320251, Length=424, Percent_Identity=29.7169811320755, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6321053, Length=423, Percent_Identity=28.6052009456265, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6321629, Length=494, Percent_Identity=27.1255060728745, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319542, Length=436, Percent_Identity=28.6697247706422, Blast_Score=196, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6324924, Length=468, Percent_Identity=29.9145299145299, Blast_Score=196, Evalue=9e-51,
Organism=Saccharomyces cerevisiae, GI6322967, Length=516, Percent_Identity=26.1627906976744, Blast_Score=189, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6324981, Length=504, Percent_Identity=29.5634920634921, Blast_Score=177, Evalue=4e-45,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=25.8660508083141, Blast_Score=166, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6320364, Length=490, Percent_Identity=23.8775510204082, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667468, Length=369, Percent_Identity=22.4932249322493, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666159, Length=436, Percent_Identity=20.4128440366972, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512776, Length=436, Percent_Identity=20.4128440366972, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53633; Mature: 53633

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILKTLTLNGFPKGKGGDYMMDQNKGLKRELKSKHIFMIALGGVIGTGLFLGSGYTIHEA
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHCCCEEEEEC
GPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCC
SATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVIT
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IIAFIILGGAAMFGFLDMKGNEPAPMFSSFIDYGGLFPNGLSAILITMIAVNFSFQGTEL
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEE
VGIAAGESENPEKTIPKAINNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKI
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECC
GIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHH
STIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEH
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHHHCCHHHHHHH
IEKTDTTEVENL
HHCCCCCCCCCC
>Mature Secondary Structure
MILKTLTLNGFPKGKGGDYMMDQNKGLKRELKSKHIFMIALGGVIGTGLFLGSGYTIHEA
CEEEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECHHHHHHHHHCCCEEEEEC
GPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCC
SATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVIT
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
IIAFIILGGAAMFGFLDMKGNEPAPMFSSFIDYGGLFPNGLSAILITMIAVNFSFQGTEL
HHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEE
VGIAAGESENPEKTIPKAINNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKI
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECC
GIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIV
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHH
STIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
FKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEH
ECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHHHHHHHHHHHHHCCHHHHHHH
IEKTDTTEVENL
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704263; 9384377; 8550462; 8867804 [H]